2-AMINOINDAN-2-CARBOXYLIC ACID

The 1H-Indene-2-carboxylicacid, 2-amino-2,3-dihydro-, with the CAS registry number 27473-62-7, is also known as 2-Amino-2-carboxyindan. It belongs to the product categories of Pharmacetical; Carboxylic Acids; Carboxylic Acids; Fused Ring Systems. This chemical's molecular formula is C₁₀H₁₁NO₂ and molecular weight is 177.2. What's more, its IUPAC name is 2-amino-1,3-dihydroindene-2-carboxylic acid. 

Physical properties of 1H-Indene-2-carboxylicacid, 2-amino-2,3-dihydro- are: (1)ACD/LogP: 1.45; (2)# of Rule of 5 Violations: 0; (3)ACD/BCF (pH 5.5): 1; (4)ACD/KOC (pH 5.5): 1; (5)#H bond acceptors: 3; (6)#H bond donors: 3; (7)#Freely Rotating Bonds: 2; (8)Polar Surface Area: 29.54 Å²; (9)Index of Refraction: 1.619; (10)Molar Refractivity: 47.99 cm³; (11)Molar Volume: 136.7 cm³; (12)Surface Tension: 60 dyne/cm; (13)Density: 1.295 g/cm³; (14)Flash Point: 169.8 °C; (15)Enthalpy of Vaporization: 63.57 kJ/mol; (16)Boiling Point: 357.1 °C at 760 mmHg; (17)Vapour Pressure: 1.02E-05 mmHg at 25°C.

Preparation: this chemical can be prepared by spiro[imidazolidine-4,2'-indan]-2,5-dione by heating. This reaction will need reagent 40% aq. NaOH and various solvent(s) with the reaction time of 24 hours. The yield is about 82%.

Uses of 1H-Indene-2-carboxylicacid, 2-amino-2,3-dihydro-: it can be used to produce Na-Fmoc-2-aminoindan-2-carboxylic acid at the temperature of 0 °C. It will need reagent 10% aq. Na₂CO₃ and solvent dioxane with the reaction time of 2 hours. The yield is about 81%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1C2=CC=CC=C2CC1(C(=O)O)N
(2)InChI: InChI=1S/C10H11NO2/c11-10(9(12)13)5-7-3-1-2-4-8(7)6-10/h1-4H,5-6,11H2,(H,12,13)
(3)InChIKey: UHQFXIWMAQOCAN-UHFFFAOYSA-N