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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Imidazo[1,2-a]pyridine Manufacturer/High quality/Best price/In stock

Cas:274-76-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Imidazo[1,2-A]Pyridine supplier in China

Cas:274-76-0

Min.Order:1 Kilogram

Negotiable

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Large Stock 99.0% imidazo(1,2-A)pyridine 274-76-0 Producer

Cas:274-76-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 274-76-0 with best quality

Cas:274-76-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Imidazo[1,2-a]pyridine/ LIDE PHARMA- Factory supply / Best price

Cas:274-76-0

Min.Order:0

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Imidazo[1,2-a]pyridine CAS:274-76-0

Cas:274-76-0

Min.Order:1 Kilogram

FOB Price: $30.0 / 40.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Imidazo[1,2-a]pyridine 274-76-0

Cas:274-76-0

Min.Order:1 Kilogram

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:274-76-0

Cas:274-76-0

Min.Order:0

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Imidazo[1,2-A]Pyridine

Cas:274-76-0

Min.Order:0

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Type:Manufacturers

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Imidazo[1,2-a]pyridine

Cas:274-76-0

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Henan Tianfu Chemical Co., Ltd.

Imidazo[1,2-a]pyridine Imidazo[1,2-a]pyridine CAS No.: 274-76-0 Synonyms: imidazo[1,2-a]-pyridine; 1H-imidazo[1,2-a]pyridine; Formula: C7H6N2 Exact Mass: 118.05300 Molecular Weight: 118.13600 PSA: 17.30000 LogP: 1.33430 Properties D

CAS274-76-0 Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:1 Kilogram

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TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:1 Kilogram

FOB Price: $2.0

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

274-76-0 CAS NO.274-76-0

Cas:274-76-0

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:100 Gram

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

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Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Imidazo[1, 2-a]pyridine cas no. 274-76-0 98%

Cas:274-76-0

Min.Order:0

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Greenutra Resource Inc

imidazo(1,2-A)pyridineAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

imidazo(1,2-A)pyridine

Cas:274-76-0

Min.Order:0

Negotiable

Type:Trading Company

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Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

imidazo(1,2-A)pyridine

Cas:274-76-0

Min.Order:0

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Type:Other

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

IMidazo[1,2-a]pyridine

Cas:274-76-0

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GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

Negotiable

Type:Manufacturers

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Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Imidazo[1,2-A]Pyridine

Cas:274-76-0

Min.Order:0

Negotiable

Type:Manufacturers

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Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

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Type:Trading Company

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

IMidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

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HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

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Type:Trading Company

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BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white to yellow powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as

Imidazo[1,2-a]pyridine

Cas:274-76-0

Min.Order:0

Negotiable

Type:Trading Company

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Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

274-76-0

Cas:274-76-0

Min.Order:0

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Hangzhou Fandachem Co.,Ltd

Imidazo[1,2-a]pyridine cas 274-76-0Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Imidazo[1,2-a]pyridine cas 274-76-0

Cas:274-76-0

Min.Order:0

Negotiable

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Best quality with low price Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Shanghai

imidazo(1,2-A)pyridine

Cas:274-76-0

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Synthetic route

2-aminopyridine
504-29-0

2-aminopyridine

2-chloroethanal
107-20-0

2-chloroethanal

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
at 70℃;100%
With sodium hydrogencarbonate In ethanol for 2h; Heating;90%
In water; butan-1-ol at 130℃; for 12h;90%
imidazo[1,2-a]pyridine-3-carboxylic acid
6200-60-8

imidazo[1,2-a]pyridine-3-carboxylic acid

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With C46H48N6O5Pd; potassium acetate In N,N-dimethyl acetamide at 160℃; for 24h; Inert atmosphere;99%
3-bromoimidazo[1,2-a]pyridine
4926-47-0

3-bromoimidazo[1,2-a]pyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; palladium diacetate; triphenylphosphine In tetrahydrofuran at 25℃; for 2h; Inert atmosphere;83%
7,7-(3-Oxa-1,5-pentanediyl)-7,8-dihydroimidazo<1,2-a>pyrazinium perchlorate

7,7-(3-Oxa-1,5-pentanediyl)-7,8-dihydroimidazo<1,2-a>pyrazinium perchlorate

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sodium hydroxide In methanol for 2h; Heating;72%
2-aminopyridine
504-29-0

2-aminopyridine

Bromoacetaldehyde diethyl acetal
2032-35-1

Bromoacetaldehyde diethyl acetal

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Stage #1: Bromoacetaldehyde diethyl acetal With hydrogenchloride In ethanol for 1.5h; Reflux;
Stage #2: 2-aminopyridine With sodium hydrogencarbonate at 20℃; for 2h; pH=Ca. 7;
62.2%
Stage #1: Bromoacetaldehyde diethyl acetal With hydrogenchloride In water at 80℃; for 0.5h;
Stage #2: 2-aminopyridine With sodium hydrogencarbonate In water at 20℃; for 2h; pH=7;
55.9%
With sodium carbonate In 1,4-dioxane; water for 22h; Cyclization; Tschitschibabin reaction; Heating;19%
3,5-dibromoimidazo<1,2-a>pyridine
69214-12-6

3,5-dibromoimidazo<1,2-a>pyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With hydrazine hydrate In ethanol for 12h; Heating;34%
With hydrazine hydrate In ethanol for 12h; Product distribution; Heating; various solvents and reaction conditions;
5-bromo-3-nitroimidazo<1,2-a>pyridine
111753-05-0

5-bromo-3-nitroimidazo<1,2-a>pyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With hydrazine hydrate In ethanol for 0.5h; Heating;20%
With hydrazine hydrate In ethanol for 0.5h; Product distribution; Heating; various solvents and reaction conditions;
5-chloro-2-pyridylamine
1072-98-6

5-chloro-2-pyridylamine

3-chloro-2-hydroxy-naphthalene-1,4-dione
1526-73-4

3-chloro-2-hydroxy-naphthalene-1,4-dione

A

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

B

2-chloro-6,11-dihydro-6,11-dioxo-naphtho-[2',3':4,5]imidazo[1,2-a]pyridine
192654-05-0

2-chloro-6,11-dihydro-6,11-dioxo-naphtho-[2',3':4,5]imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sodium bicarbonate; sodium chloride In 1,2-dimethoxyethane; dichloromethane; waterA n/a
B 4%
2,3-Dichloro-1,4-naphthoquinone
117-80-6

2,3-Dichloro-1,4-naphthoquinone

2-Amino-4-chloropyridine
19798-80-2

2-Amino-4-chloropyridine

A

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

B

10-chloro-5,6-dihydro-5,6-dioxonaphtho-[1',2':4,5]imidazo[1,2-a]pyridine
192654-11-8

10-chloro-5,6-dihydro-5,6-dioxonaphtho-[1',2':4,5]imidazo[1,2-a]pyridine

Conditions
ConditionsYield
In methanol; glycerolA n/a
B 2%
1,2-dihydro-1,2-dioxo-4-sulfonate of potassium naphthalene

1,2-dihydro-1,2-dioxo-4-sulfonate of potassium naphthalene

2-amino-5-fluoropyridine
21717-96-4

2-amino-5-fluoropyridine

A

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

B

5,6-Dihydro-5,6-dioxo-5-fluoro-naphtho[1',2':4,5]imidazo[1,2-a] pyridine

5,6-Dihydro-5,6-dioxo-5-fluoro-naphtho[1',2':4,5]imidazo[1,2-a] pyridine

Conditions
ConditionsYield
In waterA n/a
B 2%
2-aminopyridine
504-29-0

2-aminopyridine

1-bromo-2,2-dimethoxyethane
7252-83-7

1-bromo-2,2-dimethoxyethane

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
at 150 - 160℃; im Rohr;
Stage #1: 2-aminopyridine; 1-bromo-2,2-dimethoxyethane With hydrogenchloride In 1,4-dioxane; water Reflux;
Stage #2: With sodium hydrogencarbonate In 1,4-dioxane; water for 22h; Reflux;
Stage #1: 2-aminopyridine; 1-bromo-2,2-dimethoxyethane With hydrogenchloride In 1,4-dioxane; water Reflux;
Stage #2: With sodium hydrogencarbonate In 1,4-dioxane; water for 22h; Reflux;
Stage #1: 2-aminopyridine; 1-bromo-2,2-dimethoxyethane With hydrogenchloride In water Reflux;
Stage #2: With sodium hydrogencarbonate In 1,4-dioxane; water for 22h; Reflux;
Stage #1: 2-aminopyridine; 1-bromo-2,2-dimethoxyethane With hydrogenchloride In 1,4-dioxane; water Reflux;
Stage #2: With sodium hydrogencarbonate In 1,4-dioxane; water for 22h; Reflux;
2-aminopyridine
504-29-0

2-aminopyridine

bromoacetaldehyde
17157-48-1

bromoacetaldehyde

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
at 200 - 210℃; im Rohr;
In ethanol Heating;
2-Morpholinomethyl-1-(2-propynyl)-imidazole
85102-38-1

2-Morpholinomethyl-1-(2-propynyl)-imidazole

A

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

B

7,7-(3-Oxa-1,5-pentanediyl)-7,8-dihydroimidazo<1,2-a>pyrazinium perchlorate

7,7-(3-Oxa-1,5-pentanediyl)-7,8-dihydroimidazo<1,2-a>pyrazinium perchlorate

Conditions
ConditionsYield
With perchloric acid; water 1.) MeOH, 5 h, reflux; Yield given. Multistep reaction. Yields of byproduct given;
With perchloric acid; water In methanol Mechanism; Product distribution;
With perchloric acid; water 1.) MeOH, 50 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
1H-imidazo<1,2-a>pyridinium-8-carboxylate
74149-50-1

1H-imidazo<1,2-a>pyridinium-8-carboxylate

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
at 250 - 270℃; for 4h;
2,3-dihydro-imidazole<1,2-α>pyridine

2,3-dihydro-imidazole<1,2-α>pyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With water; sodium hydrogencarbonate; potassium hexacyanoferrate(III)
With lead(IV) acetate; benzene
2-Amino-6-bromopyridine
19798-81-3

2-Amino-6-bromopyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 79 percent / ethanol / 6 h / Heating
2: 90 percent / fuming nitric acid, conc. sulphuric acid
3: hydrazine hydrate / ethanol / 0.5 h / Heating; various solvents and reaction conditions
View Scheme
Multi-step reaction with 3 steps
1: 79 percent / ethanol / 6 h / Heating
2: 80 percent / N-bromosuccinimide / CH2Cl2; CHCl3 / Ambient temperature
3: hydrazine hydrate / ethanol / 12 h / Heating; various solvents and reaction conditions
View Scheme
5-bromoimidazo<1,2-a>pyridine
69214-09-1

5-bromoimidazo<1,2-a>pyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / fuming nitric acid, conc. sulphuric acid
2: hydrazine hydrate / ethanol / 0.5 h / Heating; various solvents and reaction conditions
View Scheme
Multi-step reaction with 2 steps
1: 80 percent / N-bromosuccinimide / CH2Cl2; CHCl3 / Ambient temperature
2: hydrazine hydrate / ethanol / 12 h / Heating; various solvents and reaction conditions
View Scheme
2-chloro-3-pyridinecarbonitrile
6602-54-6

2-chloro-3-pyridinecarbonitrile

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 3.8 g / 0.08 h / 130 °C
2: 1.) aq. sodium hydroxide, 2.) aq. HCl / 1.) reflux, 3 - 4 h, 2.) heating, 10 min
3: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
4: 4 h / 250 - 270 °C
View Scheme
Multi-step reaction with 5 steps
1: 3.8 g / 0.08 h / 130 °C
2: 8.3 g / aq. sodium hydroxide, hydrogen peroxide / ethanol / 1 h / 50 °C
3: 1.) aq. HCl, 2.) aq. sodium nitrite / 1.) 50 deg C, 1 h, 2.) 30 min, reflux
4: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
5: 4 h / 250 - 270 °C
View Scheme
Multi-step reaction with 5 steps
1: 3.8 g / 0.08 h / 130 °C
2: 4.2 g / Ba(OH)2*8H2O / H2O / 4 h / Heating
3: 1.7 g / aq. HCl / H2O / 0.25 h / Heating
4: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
5: 4 h / 250 - 270 °C
View Scheme
N-(3-carboxy-2-pyridyl)aminoacetaldehyde
74149-49-8

N-(3-carboxy-2-pyridyl)aminoacetaldehyde

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
2: 4 h / 250 - 270 °C
View Scheme
N-(3-cyano-2-pyridyl)aminoacetaldehyde dimethyl acetal
74149-44-3

N-(3-cyano-2-pyridyl)aminoacetaldehyde dimethyl acetal

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) aq. sodium hydroxide, 2.) aq. HCl / 1.) reflux, 3 - 4 h, 2.) heating, 10 min
2: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
3: 4 h / 250 - 270 °C
View Scheme
Multi-step reaction with 4 steps
1: 8.3 g / aq. sodium hydroxide, hydrogen peroxide / ethanol / 1 h / 50 °C
2: 1.) aq. HCl, 2.) aq. sodium nitrite / 1.) 50 deg C, 1 h, 2.) 30 min, reflux
3: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
4: 4 h / 250 - 270 °C
View Scheme
Multi-step reaction with 4 steps
1: 4.2 g / Ba(OH)2*8H2O / H2O / 4 h / Heating
2: 1.7 g / aq. HCl / H2O / 0.25 h / Heating
3: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
4: 4 h / 250 - 270 °C
View Scheme
N-(3-carboxamido-2-pyridyl)aminoacetaldehyde dimethyl acetal
74149-47-6

N-(3-carboxamido-2-pyridyl)aminoacetaldehyde dimethyl acetal

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) aq. HCl, 2.) aq. sodium nitrite / 1.) 50 deg C, 1 h, 2.) 30 min, reflux
2: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
3: 4 h / 250 - 270 °C
View Scheme
N-(3-carboxy-2-pyridyl)aminoacetaldehyde dimethyl acetal
74149-46-5

N-(3-carboxy-2-pyridyl)aminoacetaldehyde dimethyl acetal

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.7 g / aq. HCl / H2O / 0.25 h / Heating
2: 0.9 g / sodium acetate, acetic anhydride / 0.5 h / Heating
3: 4 h / 250 - 270 °C
View Scheme
2-Morpholinomethyl-1-(2-propynyl)-imidazole
85102-38-1

2-Morpholinomethyl-1-(2-propynyl)-imidazole

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) water, 2.) HClO4 / 1.) MeOH, 50 deg C, 2 h
2: 72 percent / aq. NaOH / methanol / 2 h / Heating
View Scheme
2-aminopyridine
504-29-0

2-aminopyridine

aqueous chloroacetaldehyde

aqueous chloroacetaldehyde

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With ammonia In methanol
2-chloropyridine
109-09-1

2-chloropyridine

5-chloro-2-pyridylamine
1072-98-6

5-chloro-2-pyridylamine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With trichlorophosphate
1,2,3-triazole
288-36-8

1,2,3-triazole

2-bromo-pyridine
109-04-6

2-bromo-pyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Conditions
ConditionsYield
at 160℃; for 14h;
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

3-(4-methoxylphenyl)imidazo[1,2-a]pyridine
1338248-76-2

3-(4-methoxylphenyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With C27H22N4O2Pd; potassium acetate In N,N-dimethyl acetamide at 140℃; for 18h; Catalytic behavior; Schlenk technique; Inert atmosphere;100%
With palladium 10% on activated carbon; potassium acetate In i-Amyl alcohol at 150℃; for 16h; Inert atmosphere; Green chemistry;93%
With palladium diacetate; potassium hydroxide In water at 100℃; for 24h; Inert atmosphere;80%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

4-bromobenzenecarbonitrile
623-00-7

4-bromobenzenecarbonitrile

4-(imidazo[1,2-a]pyridin-3-yl)benzonitrile
59182-08-0

4-(imidazo[1,2-a]pyridin-3-yl)benzonitrile

Conditions
ConditionsYield
With C27H22N4O2Pd; potassium acetate In N,N-dimethyl acetamide at 140℃; for 18h; Catalytic behavior; Schlenk technique; Inert atmosphere;100%
With sodium acetate In N,N-dimethyl acetamide at 166℃; for 12h; Inert atmosphere; Sonication; regioselective reaction;95%
With palladium 10% on activated carbon; potassium acetate In N,N-dimethyl acetamide at 150℃; for 16h; Solvent; Inert atmosphere;94%
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;80%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

para-bromoacetophenone
99-90-1

para-bromoacetophenone

1-(4-(imidazo[1,2-a]pyridin-3-yl)phenyl)ethan-1-one
59182-04-6

1-(4-(imidazo[1,2-a]pyridin-3-yl)phenyl)ethan-1-one

Conditions
ConditionsYield
With C26H22Cl2FN3OPd; potassium acetate In N,N-dimethyl acetamide at 140℃; for 18h; Heck Reaction; Schlenk technique; Inert atmosphere;100%
With C27H22N4O2Pd; potassium acetate In N,N-dimethyl acetamide at 140℃; for 18h; Catalytic behavior; Schlenk technique; Inert atmosphere;100%
With palladium 10% on activated carbon; potassium acetate In i-Amyl alcohol at 150℃; for 16h; Inert atmosphere; Green chemistry;96%
With sodium acetate In N,N-dimethyl acetamide at 166℃; for 12h; Inert atmosphere; Sonication; regioselective reaction;94%
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;92%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

bromobenzene
108-86-1

bromobenzene

3-phenylimidazo[1,2-a]pyridine
92961-15-4

3-phenylimidazo[1,2-a]pyridine

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide Inert atmosphere; Schlenk technique;100%
With C26H22Cl2FN3OPd; potassium acetate In N,N-dimethyl acetamide at 140℃; for 18h; Reagent/catalyst; Heck Reaction; Schlenk technique; Inert atmosphere;99%
With palladium diacetate; potassium hydroxide In water at 100℃; for 24h; Inert atmosphere;58%
With potassium acetate; palladium diacetate In N,N-dimethyl-formamide at 160℃; for 1h; Microwave irradiation; Inert atmosphere;58%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

1,2-benzenedithiole
17534-15-5

1,2-benzenedithiole

imidazolium[1,2-a]pyridine benzene 1-thiol 2-thiolate

imidazolium[1,2-a]pyridine benzene 1-thiol 2-thiolate

Conditions
ConditionsYield
at 5 - 8℃; Inert atmosphere; Glovebox; Sealed tube; Sonication; Green chemistry;100%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

3-methoxyphenyl bromide
2398-37-0

3-methoxyphenyl bromide

3-(3-methoxyphenyl)imidazo[1,2-a]pyridine
1338248-69-3

3-(3-methoxyphenyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With C27H22N4O2Pd; potassium acetate In N,N-dimethyl acetamide at 140℃; for 18h; Catalytic behavior; Schlenk technique; Inert atmosphere;100%
With palladium diacetate; potassium hydroxide In water at 100℃; for 24h; Inert atmosphere;53%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

1-tert-butyl-4-iodobenzene
35779-04-5

1-tert-butyl-4-iodobenzene

2,3-bis((4-tert-butylphenyl)thio)imidazo[1,2-a]pyridine

2,3-bis((4-tert-butylphenyl)thio)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sulfur; copper(l) iodide; potassium tert-butylate In acetic acid; N,N-dimethyl-formamide at 130℃; for 24h; Sealed tube;99%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

toluene-4-sulfonic acid hydrazide
1576-35-8

toluene-4-sulfonic acid hydrazide

3-(p-tolylthio)imidazo[1,2-a]pyridine

3-(p-tolylthio)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; propylene glycol dimethyl ether dimer at 100℃; for 12h; Schlenk technique;99%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

1-benzyl-5-(2-bromophenyl)tetrazole

1-benzyl-5-(2-bromophenyl)tetrazole

3-(2-(1-benzyltetrazol-5-yl)phenyl)imidazo[1,2-a]pyridine

3-(2-(1-benzyltetrazol-5-yl)phenyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With PdCl(1,4-bis(diphenylphosphino)butane)(C3H5); potassium pivalate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere; Schlenk technique;98%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

3-nitrosoimidazo[1,2-a]pyridine

3-nitrosoimidazo[1,2-a]pyridine

Conditions
ConditionsYield
With tert.-butylnitrite In acetonitrile at 70℃; for 0.25h; regioselective reaction;97%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

2-Bromobiphenyl
2052-07-5

2-Bromobiphenyl

3-([1,1'-biphenyl]-2-yl)imidazo[1,2-a]pyridine

3-([1,1'-biphenyl]-2-yl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With PdCl(1,4-bis(diphenylphosphino)butane)(C3H5); potassium acetate at 150℃; for 16h; Inert atmosphere; Schlenk technique;96%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

2-((difluoromethyl)thio)isoindoline-1,3-dione

2-((difluoromethyl)thio)isoindoline-1,3-dione

3-[(difluoromethyl)thio]-imidazo[1,2-a]pyridine

3-[(difluoromethyl)thio]-imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sodium chloride In N,N-dimethyl-formamide at 80℃; for 16h; Schlenk technique; Inert atmosphere;95%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

diphenyl diselenide
1666-13-3

diphenyl diselenide

3-(phenylselanyl)imidazo[1,2-a]pyridine

3-(phenylselanyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With potassium iodate; glycerol In neat (no solvent) at 110℃; for 3h; Inert atmosphere; Schlenk technique; regioselective reaction;95%
With ammonium iodide In acetonitrile at 20℃; for 18h;89%
With bis-[(trifluoroacetoxy)iodo]benzene In dichloromethane at 20℃; for 0.0833333h; regioselective reaction;88%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

sodium S-(6-chloro-1H-indol-3-yl) thiosulfate

sodium S-(6-chloro-1H-indol-3-yl) thiosulfate

3-((6-chloro-1H-indol-3-yl)thio)imidazo[1,2-a]pyridine

3-((6-chloro-1H-indol-3-yl)thio)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With iodine In dimethyl sulfoxide at 80℃; for 24h; Schlenk technique; Sealed tube; Inert atmosphere; regioselective reaction;95%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

1-bromo-4-(trifluoromethoxy)benzene
407-14-7

1-bromo-4-(trifluoromethoxy)benzene

3-(4-(trifluoromethoxy)phenyl)imidazo[1,2-a]pyridine

3-(4-(trifluoromethoxy)phenyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;95%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

3-bromoquinoline
5332-24-1

3-bromoquinoline

3-(imidazo[1,2-a]pyridin-3-yl)quinoline
1373494-56-4

3-(imidazo[1,2-a]pyridin-3-yl)quinoline

Conditions
ConditionsYield
With palladium 10% on activated carbon; potassium acetate In i-Amyl alcohol at 150℃; for 16h; Inert atmosphere; Green chemistry;94%
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;73%
With palladium diacetate; potassium hydroxide In water at 100℃; for 24h; Inert atmosphere;61%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

3-cyanobromobenzene
6952-59-6

3-cyanobromobenzene

3-(imidazo[1,2-a]pyridin-2-yl)benzonitrile
1373494-46-2

3-(imidazo[1,2-a]pyridin-2-yl)benzonitrile

Conditions
ConditionsYield
With sodium acetate In N,N-dimethyl acetamide at 166℃; for 12h; Inert atmosphere; Sonication; regioselective reaction;94%
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;93%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

thiophenol
108-98-5

thiophenol

3-(phenylthio)imidazo[1,2-a]pyridine
1609583-33-6

3-(phenylthio)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
Stage #1: thiophenol With N-chloro-succinimide In dichloromethane at 20℃; for 0.5h; Inert atmosphere;
Stage #2: imidazo[1,2-a]pyridine In dichloromethane at 20℃; for 0.5h; Inert atmosphere; regioselective reaction;
94%
With rose bengal In dimethyl sulfoxide for 6h; Irradiation; Molecular sieve; regioselective reaction;85%
With 5-ethyl-10-(2-hydroxylethyl)-7,8-dimethylisoalloxazinium triflate; iodine; oxygen In acetonitrile at 50℃; under 760.051 Torr; for 16h; Green chemistry; chemoselective reaction;70%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

sodium 4-bromobenzylsulfanesulfonate

sodium 4-bromobenzylsulfanesulfonate

3-((4-bromobenzyl)thio)imidazo[1,2-a]pyridine

3-((4-bromobenzyl)thio)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With iodine In dimethyl sulfoxide at 80℃; for 24h; Schlenk technique; Sealed tube; Inert atmosphere; regioselective reaction;94%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

Trichloroacetyl chloride
76-02-8

Trichloroacetyl chloride

3-(trichloroacetyl)imidazo[1,2-a]pyridine

3-(trichloroacetyl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With dmap In tetrahydrofuran for 12h; Acetylation; Heating;93%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

iodobenzene
591-50-4

iodobenzene

3-phenylimidazo[1,2-a]pyridine
92961-15-4

3-phenylimidazo[1,2-a]pyridine

Conditions
ConditionsYield
With palladium(II) complex with imidazolyl carbene ligandO; cesium acetate In N,N-dimethyl acetamide at 125℃; for 24h;93%
With cobalt(II) chloride hexahydrate; potassium acetate In N,N-dimethyl-formamide at 150℃; for 24h; Catalytic behavior; Reagent/catalyst; Solvent;92%
With palladium diacetate; potassium hydroxide In water at 100℃; for 24h; Inert atmosphere;65%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

4-methoxycarbonylphenyl bromide
619-42-1

4-methoxycarbonylphenyl bromide

methyl 4-(imidazo[1,2-a]pyridin-3-yl)benzoate
1373494-42-8

methyl 4-(imidazo[1,2-a]pyridin-3-yl)benzoate

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;93%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

1-dodecylthiol
112-55-0

1-dodecylthiol

C19H30N2S

C19H30N2S

Conditions
ConditionsYield
With copper(l) iodide; oxygen In dimethyl sulfoxide at 100℃; regioselective reaction;93%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

4-ethylacetophenone
937-30-4

4-ethylacetophenone

1-(4-ethylphenyl)-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,2-dione

1-(4-ethylphenyl)-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,2-dione

Conditions
ConditionsYield
With oxygen; copper diacetate; acetic acid In toluene at 140℃; for 12h; Schlenk technique; Sealed tube; regioselective reaction;93%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

4-fluoro-1-iodobenzene
352-34-1

4-fluoro-1-iodobenzene

2,3-bis((4-fluorophenyl)thio)imidazo[1,2-a]pyridine

2,3-bis((4-fluorophenyl)thio)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With sulfur; copper(l) iodide; potassium tert-butylate In acetic acid; N,N-dimethyl-formamide at 130℃; for 24h; Sealed tube;93%
3-Bromopyridine
626-55-1

3-Bromopyridine

imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

3-(pyridin-3-yl)imidazo[1,2-a]pyridine
930113-28-3

3-(pyridin-3-yl)imidazo[1,2-a]pyridine

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;92%
With potassium carbonate; triphenylphosphine; palladium diacetate In 1,4-dioxane; ethanol at 130℃; for 1h; microwave irradiation;90%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

2-(imidazo[1,2-a]pyridin-3-yl)benzonitrile
1373494-50-8

2-(imidazo[1,2-a]pyridin-3-yl)benzonitrile

Conditions
ConditionsYield
With potassium acetate; palladium diacetate In N,N-dimethyl acetamide at 150℃; for 16h; Inert atmosphere;92%
With palladium 10% on activated carbon; potassium acetate In pentan-1-ol at 150℃; for 16h; Solvent; Inert atmosphere; Green chemistry;92%
imidazo[1,2-a]pyridine
274-76-0

imidazo[1,2-a]pyridine

chlorobenzene
108-90-7

chlorobenzene

3-phenylimidazo[1,2-a]pyridine
92961-15-4

3-phenylimidazo[1,2-a]pyridine

Conditions
ConditionsYield
With NHC-Pd(II)-Im; sodium t-butanolate In tetrahydrofuran at 120℃; for 12h; Catalytic behavior; Reagent/catalyst; Solvent; Inert atmosphere;92%
With NHC-Pd(II)-Im; sodium t-butanolate In tetrahydrofuran at 120℃; for 12h; Reagent/catalyst; Solvent; Inert atmosphere;92%
With palladium diacetate; potassium hydroxide In water at 100℃; for 24h; Inert atmosphere;54%

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