2-(2-azidoethoxy)ethanol
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With water; triphenylphosphine In tetrahydrofuran for 4h; Ambient temperature; | 99% |
With 10% palladium on activated charcoal; hydrogen In methanol under 760.051 Torr; for 8h; | 98.3% |
With palladium on activated charcoal; hydrogen In methanol | 19.4 g |
2-(2-phthalimidoethoxy)ethanol
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With hydrazine hydrate In ethanol at 90℃; for 24h; | 74% |
C23H21F17N2O7
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With benzylamine In dichloromethane for 1.5h; UV-irradiation; | 15% |
N-(2-(2-hydroxyethoxy)ethyl)acetamide
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With hydrogenchloride; ethanol |
Conditions | Yield |
---|---|
With nickel kieselguhr; ammonia at 205℃; | |
iron-containing catalyst Product distribution / selectivity; | |
With ammonia; hydrogen; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In toluene at 155℃; under 44254.4 Torr; for 12h; Product distribution / selectivity; Autoclave; Cooling; |
2-(2-nitro-ethoxy)-ethanol
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With hydrogen; nickel In ethanol |
Conditions | Yield |
---|---|
With ammonia In ethanol |
Conditions | Yield |
---|---|
In water at 33.6 - 75.9℃; Thermodynamic data; Equilibrium constant; ΔH,ΔG, ΔS; |
B
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With water at 95℃; Rate constant; |
ammonia
diethylene glycol
A
morpholine
B
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
at 205℃; |
Conditions | Yield |
---|---|
In water at 26.85℃; Equilibrium constant; Further Variations:; Temperatures; |
diethylene glycol
A
morpholine
B
2-methoxy-ethanol
C
ethylamine
D
2-methoxyethylamine
E
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With ammonia; hydrogen In water at 190℃; Product distribution / selectivity; | |
With ammonia; hydrogen In water at 200℃; Product distribution / selectivity; |
ethenol
sodium carbonate
2-(2-Chloroethoxy)ethanol
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With ammonia | 16.4 g (43%) |
Conditions | Yield |
---|---|
With ammonia; hydrogen; catalyst containing 28.1percent by weight of Ni, calculated as NiO; 27.7percent by weight of Co, calculated as CoO; 13.1percent by weight of Cu, calculated as CuO; 31.2percent by weight of Zr, calculated as ZrO2 mixed with graphite at 192 - 198℃; under 150015 Torr; Product distribution / selectivity; | |
With ammonia; hydrogen; catalyst comprising 20.3 weight percent Ni, 20.2 weight percent Co, 10.6 weight percent Cu, 7.5 weight percent Mo, reminder up to 100percent is ZrO2 at 200℃; under 135014 - 150015 Torr; for 12h; Product distribution / selectivity; Autoclave; | |
With ammonia; hydrogen; 22.0 wtpercent NiO/21.5 wtpercent CoO/10.5 wtpercent CuO/0.6 wtpercent Bi2O3/ZrO2 at 200℃; under 135014 - 150015 Torr; for 10h; Product distribution / selectivity; | A 20.9 %Chromat. B 34.6 %Chromat. |
diethylene glycol
A
morpholine
B
N-ethylmorpholine;
C
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With ammonia; fixed-bed catalyst at 215℃; under 150015 Torr; Hydrogen atmosphere; |
diethylene glycol
A
morpholine
B
2-methoxy-ethanol
C
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With ammonia; hydrogen at 200℃; under 135014 - 150015 Torr; for 12h; Autoclave; | A 18.2 %Chromat. B 0.2 %Chromat. C 26.3 %Chromat. |
diethylene glycol
A
morpholine
B
2,2'-diaminodiethyl ether
C
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With ammonia; C28H44BNOP2Ru In toluene at 155℃; under 30528.1 Torr; for 12h; Product distribution / selectivity; Autoclave; Inert atmosphere; | |
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In para-xylene at 155℃; under 33003.3 Torr; for 24h; Product distribution / selectivity; Autoclave; Inert atmosphere; | |
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 155℃; under 32253.2 Torr; for 12h; Product distribution / selectivity; Autoclave; |
diethylene glycol
A
2,2'-diaminodiethyl ether
B
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With ammonia; hydrogen; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 135℃; under 42829.3 Torr; for 12h; Product distribution / selectivity; Autoclave; Cooling; | |
With chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); ammonia at 155℃; for 12h; Inert atmosphere; Autoclave; |
phthalic anhydride
2-(2-Aminoethoxy)ethanol
2-(2-phthalimidoethoxy)ethanol
Conditions | Yield |
---|---|
In toluene for 4h; Heating; | 100% |
In toluene for 4h; Reflux; | 100% |
In toluene for 24h; Reflux; | 100% |
di-tert-butyl dicarbonate
2-(2-Aminoethoxy)ethanol
2-(2-tert-butyloxycarbonylaminoethoxy)ethanol
Conditions | Yield |
---|---|
In dichloromethane at 20℃; | 100% |
In tetrahydrofuran; water at 20℃; for 16h; | 100% |
In ethanol at 0 - 20℃; for 2h; Inert atmosphere; | 100% |
benzyl chloroformate
2-(2-Aminoethoxy)ethanol
2-<2-N-(benzyloxycarbonyl)aminoethoxy>ethanol
Conditions | Yield |
---|---|
In 2-methyl-THF at 10 - 20℃; | 100% |
With triethylamine In dichloromethane at 0 - 20℃; for 20h; | 97% |
With triethylamine In tetrahydrofuran at 20℃; for 1h; Inert atmosphere; | 96% |
2-([(tert-butoxy)carbonyl]{2-[(4-methoxybenzyl)amino]-2-oxoethyl}amino)acetic acid
2-(2-Aminoethoxy)ethanol
{[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution; | 100% |
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h; | 7% |
N-((tert-butyloxy)carbonyl)-N'-(2-(3-methoxyphenyl)ethyl)iminodiacetic acid monoamide
2-(2-Aminoethoxy)ethanol
{[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-{[2-(3-methoxy-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution; | 100% |
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h; | 13% |
N-((tert-butyloxy)carbonyl)-N'-(5-((benzyloxycarbonyl)amino)-5-(methoxycarbonyl)pentyl)iminodiacetic acid monoamide
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution; | 100% |
N-((tert-butyloxy)carbonyl)-N'-(4-(1',4'-dioxolano)piperidino)iminodiacetic acid monoamide
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution; | 100% |
ethyl trifluoroacetate,
2-(2-Aminoethoxy)ethanol
2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)-ethyl]acetamide
Conditions | Yield |
---|---|
In methanol | 100% |
With triethylamine In methanol at 20℃; | 83% |
In methanol at 20℃; for 3h; | 80% |
With triethylamine In methanol at 20℃; for 3h; | 80% |
With triethylamine for 24h; | 161 g |
benzyl bromide
2-(2-Aminoethoxy)ethanol
2-(N,N-dibenzyl-2-aminoethoxy)ethanol
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile for 2h; Reflux; | 100% |
With potassium carbonate In acetonitrile at 50 - 55℃; for 3.5h; | 97% |
With potassium carbonate In acetonitrile Reflux; | 89.2% |
acrylic acid methyl ester
2-(2-Aminoethoxy)ethanol
3-[[2-(2-hydroxy-ethoxy)-ethyl]-(2-methoxycarbonyl-ethyl)-amino]-propionoic acid methyl ester
Conditions | Yield |
---|---|
In methanol at 20℃; for 48h; Michael addition; | 100% |
In methanol at 30℃; for 72h; Inert atmosphere; | 99% |
2-(2-Aminoethoxy)ethanol
2-(2-aminoethoxy)ethanol hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In ethanol at 0℃; for 0.5h; | 100% |
With hydrogenchloride In methanol for 0.5h; |
di-tert-butyl dicarbonate
2-(2-Aminoethoxy)ethanol
2-(2-tert-butyloxycarbonylaminoethoxy)ethanol
Conditions | Yield |
---|---|
In tetrahydrofuran | 100% |
2-(2-Aminoethoxy)ethanol
n-hexadecanoyl chloride
N-(ω-hydroxyethoxyethyl)hexadecanamide
Conditions | Yield |
---|---|
Stage #1: 2-(2-Aminoethoxy)ethanol With magnesium oxide In tetrahydrofuran; water at 5℃; for 0.5h; Stage #2: n-hexadecanoyl chloride In tetrahydrofuran; water at 5 - 10℃; for 2h; | 100% |
With triethylamine In dichloromethane at 0℃; for 4h; | 92% |
With magnesium oxide In tetrahydrofuran; water |
Conditions | Yield |
---|---|
Stage #1: 4-carboxybenzophenone With ammonium bicarbonate In 1,4-dioxane for 2h; Stage #2: 2-(2-Aminoethoxy)ethanol In 1,4-dioxane for 2h; | 100% |
Conditions | Yield |
---|---|
In methanol at 20℃; for 0.5h; | 100% |
Conditions | Yield |
---|---|
In chloroform | 99% |
perylene-3,4,9,10-tetracarboxylic acid 3,4:9,10-dianhydride
2-(2-Aminoethoxy)ethanol
2,9-bis(2-(2-hydroxyethoxy)ethyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 200℃; for 0.966667h; Microwave irradiation; | 99% |
at 130℃; for 3h; | 94% |
at 130℃; for 3h; Inert atmosphere; | |
With N,N-dimethyl acetamide; zinc diacetate at 160℃; for 8h; Inert atmosphere; |
ethyl 1-(2-bromoethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxylate
2-(2-Aminoethoxy)ethanol
5-(2-(2-hydroxyethoxy)ethyl)-2-(4-methoxyphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
Conditions | Yield |
---|---|
With potassium iodide for 0.0166667h; Microwave irradiation; | 99% |
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine In dichloromethane | 99% |
Conditions | Yield |
---|---|
at 90℃; for 6h; | 99% |
at 90℃; for 6h; Inert atmosphere; | 99% |
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 0.5h; | 98.8% |
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 0.5h; | 98.8% |
acetic anhydride
2-(2-Aminoethoxy)ethanol
N-(2-(2-hydroxyethoxy)ethyl)acetamide
Conditions | Yield |
---|---|
In ethanol for 0.5h; Heating; | 98% |
In ethanol at 40℃; for 0.25h; | 97% |
With dmap; triethylamine In chloroform at 65℃; for 2.5h; | 92% |
tert-butylchlorodiphenylsilane
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With 1H-imidazole for 18h; | 98% |
p-methyl red
2-(2-Aminoethoxy)ethanol
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide Acylation; | 98% |
Stage #1: p-methyl red With triethylamine; isobutyl chloroformate In tetrahydrofuran at 20℃; for 2h; Stage #2: 2-(2-Aminoethoxy)ethanol In tetrahydrofuran for 0.5h; |
1,4,5,8-naphthalenetetracarboxylic dianhydride
2-(2-Aminoethoxy)ethanol
2,7-bis(2-(2-hydroxyethoxy)ethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone
Conditions | Yield |
---|---|
In 1-methyl-pyrrolidin-2-one at 100℃; for 2h; | 98% |
In ethanol Reflux; | 89.1% |
With pyridine; zinc diacetate amidation; Heating; | 70% |
Conditions | Yield |
---|---|
Stage #1: 4-cyanobenzoic Acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 2h; Stage #2: 2-(2-Aminoethoxy)ethanol With sodium carbonate In water for 1h; Further stages.; | 98% |
4-bromo-1,8-naphthalenedicarboxylic anhydride
2-(2-Aminoethoxy)ethanol
2-[2-(2-hydroxy-ethoxy)-ethyl]-6-[2-(2-hydroxy-ethoxy)-ethylamino]-benzo[de]isoquinoline-1,3-dione
Conditions | Yield |
---|---|
In 1-methyl-pyrrolidin-2-one at 110℃; for 2h; | 98% |
Conditions | Yield |
---|---|
In hydrogenchloride | 98% |
The 2-(2-Aminoethoxy)ethanol, with the CAS registry number 929-06-6 and EINECS registry number 213-195-4, is also called β-(β-Hydroxyethoxy)ethylamine. And the molecular formula of this chemical is C4H11NO2. It is a kind of colourless to faintly yellow liquid, and belongs to the following product categries: Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols.
The physical properties of 2-(2-Aminoethoxy)ethanol are as following: (1)ACD/LogP: -1.37; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.22; (4)ACD/LogD (pH 7.4): -2.69; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 21.7 Å2; (13)Index of Refraction: 1.449; (14)Molar Refractivity: 27.39 cm3; (15)Molar Volume: 102.1 cm3; (16)Polarizability: 10.86×10-24cm3; (17)Surface Tension: 39.9 dyne/cm; (18)Density: 1.029 g/cm3; (19)Flash Point: 76.6 °C; (20)Enthalpy of Vaporization: 53.19 kJ/mol; (21)Boiling Point: 221 °C at 760 mmHg; (22)Vapour Pressure: 0.0227 mmHg at 25°C.
Preparation and uses of 2-(2-Aminoethoxy)ethanol: It is metabolite of morpholine degradation in Mycobacterium aurum, and it also can be prepared by DGA. What's more, it is used as acid gas absorber, and it is also used as surface active agent and wetting agent. It is used as the material of polymer as well.
You should be cautious while dealing with this chemical. It is harmful in contact with skin, and may also cause burns. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; Avoid contact with skin and eyes; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
You can still convert the following datas into molecular structure:
(1)SMILES: OCCOCCN
(2)InChI: InChI=1/C4H11NO2/c5-1-3-7-4-2-6/h6H,1-5H2
(3)InChIKey: GIAFURWZWWWBQT-UHFFFAOYAI
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | 2825mg/kg (2825mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(9), Pg. 50, 1988. |
rabbit | LD50 | skin | 1190uL/kg (1.19mL/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951. | |
rat | LD50 | oral | 3gm/kg (3000mg/kg) | BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(9), Pg. 50, 1988. |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View