Product Name

  • Name

    2-Aminoethoxyethanol

  • EINECS 213-195-4
  • CAS No. 929-06-6
  • Article Data38
  • CAS DataBase
  • Density 1.029 g/cm3
  • Solubility miscible in water
  • Melting Point -12.5 °C
  • Formula C4H11NO2
  • Boiling Point 221 °C at 760 mmHg
  • Molecular Weight 105.137
  • Flash Point 76.6 °C
  • Transport Information UN 3055 8/PG 3
  • Appearance colourless to faintly yellow liquid
  • Safety 26-36/37/39-45-24/25
  • Risk Codes 21-34
  • Molecular Structure Molecular Structure of 929-06-6 (2-Aminoethoxyethanol)
  • Hazard Symbols CorrosiveC
  • Synonyms 1-Amino-2-(2-hydroxyethoxy)ethane;2-(2-Aminoethoxy)ethanol;2-(2-Hydroxyethoxy)ethylamine;2-(Hydroxyethoxy)ethylamine;2-Amino-2'-hydroxydiethyl ether;2-Aminoethyl2-hydroxyethyl ether;5-Amino-3-oxapentan-1-ol;5-Hydroxy-3-oxapentylamine;Diethylene glycol amine;Diethylene glycol monoamine;Diglycolamine;Diglycolamine Agent;NSC 86108;b-(b-Hydroxyethoxy)ethylamine;b-Hydroxy-b'-aminodiethyl ether;
  • PSA 55.48000
  • LogP -0.34570

Synthetic route

2-(2-azidoethoxy)ethanol
139115-90-5

2-(2-azidoethoxy)ethanol

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With water; triphenylphosphine In tetrahydrofuran for 4h; Ambient temperature;99%
With 10% palladium on activated charcoal; hydrogen In methanol under 760.051 Torr; for 8h;98.3%
With palladium on activated charcoal; hydrogen In methanol19.4 g
2-(2-phthalimidoethoxy)ethanol
69676-63-7

2-(2-phthalimidoethoxy)ethanol

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With hydrazine hydrate In ethanol at 90℃; for 24h;74%
C23H21F17N2O7
1548723-17-6

C23H21F17N2O7

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With benzylamine In dichloromethane for 1.5h; UV-irradiation;15%
N-(2-(2-hydroxyethoxy)ethyl)acetamide
118974-46-2

N-(2-(2-hydroxyethoxy)ethyl)acetamide

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With hydrogenchloride; ethanol
diethylene glycol
111-46-6

diethylene glycol

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With nickel kieselguhr; ammonia at 205℃;
iron-containing catalyst Product distribution / selectivity;
With ammonia; hydrogen; (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine] In toluene at 155℃; under 44254.4 Torr; for 12h; Product distribution / selectivity; Autoclave; Cooling;
2-(2-nitro-ethoxy)-ethanol
20132-16-5

2-(2-nitro-ethoxy)-ethanol

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With hydrogen; nickel In ethanol
2-(2-Chloroethoxy)ethanol
628-89-7

2-(2-Chloroethoxy)ethanol

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia In ethanol
C5H10NO4(1-)
207116-18-5

C5H10NO4(1-)

A

carbon dioxide
124-38-9

carbon dioxide

B

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
In water at 33.6 - 75.9℃; Thermodynamic data; Equilibrium constant; ΔH,ΔG, ΔS;
N,N'-bis(2,3-dihydroxypropyl)-5-(2-{[2-(2-hydroxyethoxy)ethyl]amino}-2-oxoethoxy)-1,3-benzenedicarboxamide

N,N'-bis(2,3-dihydroxypropyl)-5-(2-{[2-(2-hydroxyethoxy)ethyl]amino}-2-oxoethoxy)-1,3-benzenedicarboxamide

A

[3,5-Bis-(2,3-dihydroxy-propylcarbamoyl)-phenoxy]-acetic acid

[3,5-Bis-(2,3-dihydroxy-propylcarbamoyl)-phenoxy]-acetic acid

B

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With water at 95℃; Rate constant;
ammonia
7664-41-7

ammonia

diethylene glycol
111-46-6

diethylene glycol

nickel

nickel

kieselguhr

kieselguhr

A

morpholine
110-91-8

morpholine

B

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C

amine

amine

Conditions
ConditionsYield
at 205℃;
C5H10NO4(1-)
207116-18-5

C5H10NO4(1-)

A

hydrogen carbonate
71-52-3

hydrogen carbonate

B

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
In water at 26.85℃; Equilibrium constant; Further Variations:; Temperatures;
diethylene glycol
111-46-6

diethylene glycol

A

morpholine
110-91-8

morpholine

B

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

C

ethylamine
75-04-7

ethylamine

D

2-methoxyethylamine
109-85-3

2-methoxyethylamine

E

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia; hydrogen In water at 190℃; Product distribution / selectivity;
With ammonia; hydrogen In water at 200℃; Product distribution / selectivity;
ethenol
557-75-5

ethenol

sodium carbonate
497-19-8

sodium carbonate

2-(2-Chloroethoxy)ethanol
628-89-7

2-(2-Chloroethoxy)ethanol

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia16.4 g (43%)
diethylene glycol
111-46-6

diethylene glycol

A

morpholine
110-91-8

morpholine

B

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia; hydrogen; catalyst containing 28.1percent by weight of Ni, calculated as NiO; 27.7percent by weight of Co, calculated as CoO; 13.1percent by weight of Cu, calculated as CuO; 31.2percent by weight of Zr, calculated as ZrO2 mixed with graphite at 192 - 198℃; under 150015 Torr; Product distribution / selectivity;
With ammonia; hydrogen; catalyst comprising 20.3 weight percent Ni, 20.2 weight percent Co, 10.6 weight percent Cu, 7.5 weight percent Mo, reminder up to 100percent is ZrO2 at 200℃; under 135014 - 150015 Torr; for 12h; Product distribution / selectivity; Autoclave;
With ammonia; hydrogen; 22.0 wtpercent NiO/21.5 wtpercent CoO/10.5 wtpercent CuO/0.6 wtpercent Bi2O3/ZrO2 at 200℃; under 135014 - 150015 Torr; for 10h; Product distribution / selectivity;A 20.9 %Chromat.
B 34.6 %Chromat.
diethylene glycol
111-46-6

diethylene glycol

A

morpholine
110-91-8

morpholine

B

N-ethylmorpholine;
100-74-3

N-ethylmorpholine;

C

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia; fixed-bed catalyst at 215℃; under 150015 Torr; Hydrogen atmosphere;
diethylene glycol
111-46-6

diethylene glycol

A

morpholine
110-91-8

morpholine

B

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

C

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia; hydrogen at 200℃; under 135014 - 150015 Torr; for 12h; Autoclave;A 18.2 %Chromat.
B 0.2 %Chromat.
C 26.3 %Chromat.
diethylene glycol
111-46-6

diethylene glycol

A

morpholine
110-91-8

morpholine

B

2,2'-diaminodiethyl ether
2752-17-2

2,2'-diaminodiethyl ether

C

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia; C28H44BNOP2Ru In toluene at 155℃; under 30528.1 Torr; for 12h; Product distribution / selectivity; Autoclave; Inert atmosphere;
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In para-xylene at 155℃; under 33003.3 Torr; for 24h; Product distribution / selectivity; Autoclave; Inert atmosphere;
With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 155℃; under 32253.2 Torr; for 12h; Product distribution / selectivity; Autoclave;
diethylene glycol
111-46-6

diethylene glycol

A

2,2'-diaminodiethyl ether
2752-17-2

2,2'-diaminodiethyl ether

B

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

Conditions
ConditionsYield
With ammonia; hydrogen; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II) In toluene at 135℃; under 42829.3 Torr; for 12h; Product distribution / selectivity; Autoclave; Cooling;
With chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); ammonia at 155℃; for 12h; Inert atmosphere; Autoclave;
phthalic anhydride
85-44-9

phthalic anhydride

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(2-phthalimidoethoxy)ethanol
69676-63-7

2-(2-phthalimidoethoxy)ethanol

Conditions
ConditionsYield
In toluene for 4h; Heating;100%
In toluene for 4h; Reflux;100%
In toluene for 24h; Reflux;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(2-tert-butyloxycarbonylaminoethoxy)ethanol
139115-91-6

2-(2-tert-butyloxycarbonylaminoethoxy)ethanol

Conditions
ConditionsYield
In dichloromethane at 20℃;100%
In tetrahydrofuran; water at 20℃; for 16h;100%
In ethanol at 0 - 20℃; for 2h; Inert atmosphere;100%
benzyl chloroformate
501-53-1

benzyl chloroformate

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-<2-N-(benzyloxycarbonyl)aminoethoxy>ethanol
145881-74-9

2-<2-N-(benzyloxycarbonyl)aminoethoxy>ethanol

Conditions
ConditionsYield
In 2-methyl-THF at 10 - 20℃;100%
With triethylamine In dichloromethane at 0 - 20℃; for 20h;97%
With triethylamine In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;96%
2-([(tert-butoxy)carbonyl]{2-[(4-methoxybenzyl)amino]-2-oxoethyl}amino)acetic acid
194996-03-7

2-([(tert-butoxy)carbonyl]{2-[(4-methoxybenzyl)amino]-2-oxoethyl}amino)acetic acid

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

{[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester
194996-45-7

{[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-[(4-methoxy-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h;7%
N-((tert-butyloxy)carbonyl)-N'-(2-(3-methoxyphenyl)ethyl)iminodiacetic acid monoamide
188625-13-0

N-((tert-butyloxy)carbonyl)-N'-(2-(3-methoxyphenyl)ethyl)iminodiacetic acid monoamide

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

{[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-{[2-(3-methoxy-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester
194996-44-6

{[2-(2-Hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-{[2-(3-methoxy-phenyl)-ethylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h;13%
N-((tert-butyloxy)carbonyl)-N'-(5-((benzyloxycarbonyl)amino)-5-(methoxycarbonyl)pentyl)iminodiacetic acid monoamide
206867-09-6

N-((tert-butyloxy)carbonyl)-N'-(5-((benzyloxycarbonyl)amino)-5-(methoxycarbonyl)pentyl)iminodiacetic acid monoamide

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-benzyloxycarbonylamino-6-[2-(tert-butoxycarbonyl-{[2-(2-hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-amino)-acetylamino]-hexanoic acid methyl ester

2-benzyloxycarbonylamino-6-[2-(tert-butoxycarbonyl-{[2-(2-hydroxy-ethoxy)-ethylcarbamoyl]-methyl}-amino)-acetylamino]-hexanoic acid methyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
N-((tert-butyloxy)carbonyl)-N'-(4-(1',4'-dioxolano)piperidino)iminodiacetic acid monoamide
215161-22-1

N-((tert-butyloxy)carbonyl)-N'-(4-(1',4'-dioxolano)piperidino)iminodiacetic acid monoamide

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

[2-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-2-oxo-ethyl]-{[(3-hydroxy-propoxymethyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester

[2-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-2-oxo-ethyl]-{[(3-hydroxy-propoxymethyl)-carbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
ethyl trifluoroacetate,
383-63-1

ethyl trifluoroacetate,

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)-ethyl]acetamide
302331-18-6

2,2,2-trifluoro-N-[2-(2-hydroxyethoxy)-ethyl]acetamide

Conditions
ConditionsYield
In methanol100%
With triethylamine In methanol at 20℃;83%
In methanol at 20℃; for 3h;80%
With triethylamine In methanol at 20℃; for 3h;80%
With triethylamine for 24h;161 g
benzyl bromide
100-39-0

benzyl bromide

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(N,N-dibenzyl-2-aminoethoxy)ethanol
136533-09-0

2-(N,N-dibenzyl-2-aminoethoxy)ethanol

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 2h; Reflux;100%
With potassium carbonate In acetonitrile at 50 - 55℃; for 3.5h;97%
With potassium carbonate In acetonitrile Reflux;89.2%
acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

3-[[2-(2-hydroxy-ethoxy)-ethyl]-(2-methoxycarbonyl-ethyl)-amino]-propionoic acid methyl ester
921227-43-2

3-[[2-(2-hydroxy-ethoxy)-ethyl]-(2-methoxycarbonyl-ethyl)-amino]-propionoic acid methyl ester

Conditions
ConditionsYield
In methanol at 20℃; for 48h; Michael addition;100%
In methanol at 30℃; for 72h; Inert atmosphere;99%
2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(2-aminoethoxy)ethanol hydrochloride
40321-53-7

2-(2-aminoethoxy)ethanol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 0℃; for 0.5h;100%
With hydrogenchloride In methanol for 0.5h;
NaHCO3 (saturated)

NaHCO3 (saturated)

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(2-tert-butyloxycarbonylaminoethoxy)ethanol
139115-91-6

2-(2-tert-butyloxycarbonylaminoethoxy)ethanol

Conditions
ConditionsYield
In tetrahydrofuran100%
2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

n-hexadecanoyl chloride
112-67-4

n-hexadecanoyl chloride

N-(ω-hydroxyethoxyethyl)hexadecanamide
20138-27-6

N-(ω-hydroxyethoxyethyl)hexadecanamide

Conditions
ConditionsYield
Stage #1: 2-(2-Aminoethoxy)ethanol With magnesium oxide In tetrahydrofuran; water at 5℃; for 0.5h;
Stage #2: n-hexadecanoyl chloride In tetrahydrofuran; water at 5 - 10℃; for 2h;
100%
With triethylamine In dichloromethane at 0℃; for 4h;92%
With magnesium oxide In tetrahydrofuran; water
4-carboxybenzophenone
611-95-0

4-carboxybenzophenone

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C18H19NO4
1579942-48-5

C18H19NO4

Conditions
ConditionsYield
Stage #1: 4-carboxybenzophenone With ammonium bicarbonate In 1,4-dioxane for 2h;
Stage #2: 2-(2-Aminoethoxy)ethanol In 1,4-dioxane for 2h;
100%
C18H21N3O4

C18H21N3O4

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C13H19NO3

C13H19NO3

Conditions
ConditionsYield
In methanol at 20℃; for 0.5h;100%
tert-butyldicarbonate
34619-03-9

tert-butyldicarbonate

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(2-Boc-aminoethoxy)-ethanol

2-(2-Boc-aminoethoxy)-ethanol

Conditions
ConditionsYield
In chloroform99%
perylene-3,4,9,10-tetracarboxylic acid 3,4:9,10-dianhydride
128-69-8

perylene-3,4,9,10-tetracarboxylic acid 3,4:9,10-dianhydride

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2,9-bis(2-(2-hydroxyethoxy)ethyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone
238755-74-3

2,9-bis(2-(2-hydroxyethoxy)ethyl)anthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-1,3,8,10(2H,9H)-tetraone

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 200℃; for 0.966667h; Microwave irradiation;99%
at 130℃; for 3h;94%
at 130℃; for 3h; Inert atmosphere;
With N,N-dimethyl acetamide; zinc diacetate at 160℃; for 8h; Inert atmosphere;
ethyl 1-(2-bromoethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxylate
1101861-36-2

ethyl 1-(2-bromoethyl)-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxylate

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

5-(2-(2-hydroxyethoxy)ethyl)-2-(4-methoxyphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
1310071-15-8

5-(2-(2-hydroxyethoxy)ethyl)-2-(4-methoxyphenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one

Conditions
ConditionsYield
With potassium iodide for 0.0166667h; Microwave irradiation;99%
(adamant-1-yl)-acetic acid
4942-47-6

(adamant-1-yl)-acetic acid

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C16H27NO3

C16H27NO3

Conditions
ConditionsYield
With benzotriazol-1-ol; 1,2-dichloro-ethane; N-ethyl-N,N-diisopropylamine In dichloromethane99%
2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

formic acid ethyl ester
109-94-4

formic acid ethyl ester

N-[2-(2-hydroxyethoxy)ethyl]formamide

N-[2-(2-hydroxyethoxy)ethyl]formamide

Conditions
ConditionsYield
at 90℃; for 6h;99%
at 90℃; for 6h; Inert atmosphere;99%
trans-4-cycloocten-yl 2,5-dioxo-1-pyrrolidinyl ester carbonic acid

trans-4-cycloocten-yl 2,5-dioxo-1-pyrrolidinyl ester carbonic acid

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C13H23NO4

C13H23NO4

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.5h;98.8%
C13H17NO5

C13H17NO5

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

C13H23NO4

C13H23NO4

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 0.5h;98.8%
acetic anhydride
108-24-7

acetic anhydride

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

N-(2-(2-hydroxyethoxy)ethyl)acetamide
118974-46-2

N-(2-(2-hydroxyethoxy)ethyl)acetamide

Conditions
ConditionsYield
In ethanol for 0.5h; Heating;98%
In ethanol at 40℃; for 0.25h;97%
With dmap; triethylamine In chloroform at 65℃; for 2.5h;92%
tert-butylchlorodiphenylsilane
58479-61-1

tert-butylchlorodiphenylsilane

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-(2'-tert-butyldiphenylsiloxyethoxy)ethylamine

2-(2'-tert-butyldiphenylsiloxyethoxy)ethylamine

Conditions
ConditionsYield
With 1H-imidazole for 18h;98%
p-methyl red
201858-51-7

p-methyl red

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

4-(4-dimethylamino-phenylazo)-N-[2-(2-hydroxy-ethoxy)-ethyl]-benzamide

4-(4-dimethylamino-phenylazo)-N-[2-(2-hydroxy-ethoxy)-ethyl]-benzamide

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide Acylation;98%
Stage #1: p-methyl red With triethylamine; isobutyl chloroformate In tetrahydrofuran at 20℃; for 2h;
Stage #2: 2-(2-Aminoethoxy)ethanol In tetrahydrofuran for 0.5h;
1,4,5,8-naphthalenetetracarboxylic dianhydride
81-30-1

1,4,5,8-naphthalenetetracarboxylic dianhydride

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2,7-bis(2-(2-hydroxyethoxy)ethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone
164932-87-0

2,7-bis(2-(2-hydroxyethoxy)ethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone

Conditions
ConditionsYield
In 1-methyl-pyrrolidin-2-one at 100℃; for 2h;98%
In ethanol Reflux;89.1%
With pyridine; zinc diacetate amidation; Heating;70%
4-cyanobenzoic Acid
619-65-8

4-cyanobenzoic Acid

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

4-cyano-N-[2-(2-hydroxy-ethoxy)-ethyl]-benzamide

4-cyano-N-[2-(2-hydroxy-ethoxy)-ethyl]-benzamide

Conditions
ConditionsYield
Stage #1: 4-cyanobenzoic Acid With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 2h;
Stage #2: 2-(2-Aminoethoxy)ethanol With sodium carbonate In water for 1h; Further stages.;
98%
4-bromo-1,8-naphthalenedicarboxylic anhydride
81-86-7

4-bromo-1,8-naphthalenedicarboxylic anhydride

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

2-[2-(2-hydroxy-ethoxy)-ethyl]-6-[2-(2-hydroxy-ethoxy)-ethylamino]-benzo[de]isoquinoline-1,3-dione
903499-39-8

2-[2-(2-hydroxy-ethoxy)-ethyl]-6-[2-(2-hydroxy-ethoxy)-ethylamino]-benzo[de]isoquinoline-1,3-dione

Conditions
ConditionsYield
In 1-methyl-pyrrolidin-2-one at 110℃; for 2h;98%
Adipic acid
124-04-9

Adipic acid

di-β-aminoethyl oxalate dihydrochloride

di-β-aminoethyl oxalate dihydrochloride

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

2-(2-Aminoethoxy)ethanol
929-06-6

2-(2-Aminoethoxy)ethanol

di-β-(β-ethoxy)-ethyl adipate dihydrochloride

di-β-(β-ethoxy)-ethyl adipate dihydrochloride

Conditions
ConditionsYield
In hydrogenchloride98%

2-(2-Aminoethoxy)ethanol Consensus Reports

Reported in EPA TSCA Inventory.

2-(2-Aminoethoxy)ethanol Standards and Recommendations

DOT Classification:  8; Label: Corrosive

2-(2-Aminoethoxy)ethanol Specification

The 2-(2-Aminoethoxy)ethanol, with the CAS registry number 929-06-6 and EINECS registry number 213-195-4, is also called β-(β-Hydroxyethoxy)ethylamine. And the molecular formula of this chemical is C4H11NO2. It is a kind of colourless to faintly yellow liquid, and belongs to the following product categries: Ethylene Glycols & Monofunctional Ethylene Glycols;Monofunctional Ethylene Glycols.

The physical properties of 2-(2-Aminoethoxy)ethanol are as following: (1)ACD/LogP: -1.37; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.22; (4)ACD/LogD (pH 7.4): -2.69; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 3; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 6; (12)Polar Surface Area: 21.7 Å2; (13)Index of Refraction: 1.449; (14)Molar Refractivity: 27.39 cm3; (15)Molar Volume: 102.1 cm3; (16)Polarizability: 10.86×10-24cm3; (17)Surface Tension: 39.9 dyne/cm; (18)Density: 1.029 g/cm3; (19)Flash Point: 76.6 °C; (20)Enthalpy of Vaporization: 53.19 kJ/mol; (21)Boiling Point: 221 °C at 760 mmHg; (22)Vapour Pressure: 0.0227 mmHg at 25°C.

Preparation and uses of 2-(2-Aminoethoxy)ethanol: It is metabolite of morpholine degradation in Mycobacterium aurum, and it also can be prepared by DGA. What's more, it is used as acid gas absorber, and it is also used as surface active agent and wetting agent. It is used as the material of polymer as well.

You should be cautious while dealing with this chemical. It is harmful in contact with skin, and may also cause burns. Therefore, you had better take the following instructions: Wear suitable protective clothing, gloves and eye/face protection, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; Avoid contact with skin and eyes; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: OCCOCCN
(2)InChI: InChI=1/C4H11NO2/c5-1-3-7-4-2-6/h6H,1-5H2
(3)InChIKey: GIAFURWZWWWBQT-UHFFFAOYAI

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 2825mg/kg (2825mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(9), Pg. 50, 1988.
rabbit LD50 skin 1190uL/kg (1.19mL/kg)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat LD50 oral 3gm/kg (3000mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(9), Pg. 50, 1988.

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