Product Name

  • Name

    2-PIPERIDYLMETHYLAMINE

  • EINECS 245-371-1
  • CAS No. 22990-77-8
  • Article Data12
  • CAS DataBase
  • Density 0.897 g/cm3
  • Solubility
  • Melting Point
  • Formula C6H14N2
  • Boiling Point 176.9 °C at 760 mmHg
  • Molecular Weight 114.191
  • Flash Point 66.7 °C
  • Transport Information UN 2735
  • Appearance Colorless clear liquid.
  • Safety 26-36/37/39-45
  • Risk Codes 34
  • Molecular Structure Molecular Structure of 22990-77-8 (2-PIPERIDYLMETHYLAMINE)
  • Hazard Symbols CorrosiveC
  • Synonyms Piperidine,2-(aminomethyl)- (6CI,7CI,8CI);
  • PSA 38.05000
  • LogP 1.11630

Synthetic route

(2-aminomethylpyridine)
3731-51-9

(2-aminomethylpyridine)

C-piperidin-2-yl-methylamine
22990-77-8

C-piperidin-2-yl-methylamine

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; platinum(IV) oxide In ethanol; water for 2.5h; Ambient temperature;28.1%
With acetic acid; platinum Hydrogenation;
With hydrogen; Ra-Ni at 160 - 200℃; under 135014 - 150015 Torr; Product distribution / selectivity;
With hydrogen; Ni-Fe-6606 at 160℃; under 150015 Torr; Product distribution / selectivity;
(+-)-6-oxo-piperidine-2-carboxylic acid amide

(+-)-6-oxo-piperidine-2-carboxylic acid amide

C-piperidin-2-yl-methylamine
22990-77-8

C-piperidin-2-yl-methylamine

Conditions
ConditionsYield
With tetrahydrofuran; lithium aluminium tetrahydride
(+-)-<1-acetyl-<2>piperidyl>-acetone oxime

(+-)-<1-acetyl-<2>piperidyl>-acetone oxime

C-piperidin-2-yl-methylamine
22990-77-8

C-piperidin-2-yl-methylamine

Conditions
ConditionsYield
With hydrogenchloride; diethyl ether; phosphorus pentachloride
(+-)-N-<2>piperidylmethyl-acetamide

(+-)-N-<2>piperidylmethyl-acetamide

C-piperidin-2-yl-methylamine
22990-77-8

C-piperidin-2-yl-methylamine

Conditions
ConditionsYield
With hydrogenchloride
hydrogenchloride
7647-01-0

hydrogenchloride

(1-acetyl-[2]piperidyl)-acetone oxime

(1-acetyl-[2]piperidyl)-acetone oxime

diethyl ether
60-29-7

diethyl ether

phosphorus pentachloride
10026-13-8, 874483-75-7

phosphorus pentachloride

water
7732-18-5

water

C-piperidin-2-yl-methylamine
22990-77-8

C-piperidin-2-yl-methylamine

2-Cyanopyridine
100-70-9

2-Cyanopyridine

C-piperidin-2-yl-methylamine
22990-77-8

C-piperidin-2-yl-methylamine

Conditions
ConditionsYield
With ammonia; hydrogen; Ni-5584 In ethanol at 180℃; under 135014 Torr; for 6h; Product distribution / selectivity;

2-(Aminomethyl)piperidine Chemical Properties

Molecular Formula: C6H14N2
Formula Weight: 114.19
bp of 2-PIPERIDYLMETHYLAMINE (22990-77-8): 63-66°C/12mm
Density: 0.897 g/cm3 
refractive index : 1.4850
Fp of 2-PIPERIDYLMETHYLAMINE (22990-77-8): 63-66°C/12mm
Vapour Pressure: 1.07 mmHg at 25°
Specific Gravity(20/4°C): 0.941
Solubility: ≥100g/100g Water at 25°C
Appearance of 2-PIPERIDYLMETHYLAMINE (22990-77-8): Colorless clear liquid.

2-(Aminomethyl)piperidine Toxicity Data With Reference

LD50 Oral Mouse (mg/kg): 1440

2-(Aminomethyl)piperidine Safety Profile

Safety: DANGER: CORROSIVE, burns skin and eyes
Hazard Codes : C (Corrosive)
Risk Statements : 34 (Causes burns)
Safety Statements : 26-36/37/39-45 (In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing, gloves and eye/face protection; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible))
RIDADR : 2735
HazardClass : 8
PackingGroup : III

2-(Aminomethyl)piperidine Standards and Recommendations

Purity of 2-PIPERIDYLMETHYLAMINE (22990-77-8) (GC%): 99.0 min.
Moisture (%): 0.1 max.
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