2,2'-Thiodiethanol supplier

Name
2,2'-Thiodiethanol
EINECS 203-874-3
CAS No. 111-48-8
Article Data56
CAS DataBase
Density 1.18 g/cm³
Solubility
Melting Point -16 ºC(lit.)
Formula C₄H₁₀O₂S
Boiling Point 282 ºC at 760 mmHg
Molecular Weight 122.188
Flash Point 139.5 ºC
Transport Information
Appearance colourless liquid with characteristic odour
Safety 23-26-36/37/39-45
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Ethanol,2,2'-thiodi- (6CI,8CI);1,5-Dihydroxy-3-thiapentane;2,2'-Dihydroxydiethylsulfide;2,2'-Thiobisethanol;2,2'-Thiodiglycol;3-Thiapentane-1,5-diol;Bis(2-hydroxyethyl) sulfide;Bis(2-hydroxyethyl)thioether;Bis(b-hydroxyethyl)sulfide;Di(2-hydroxyethyl) sulfide;Diethanol sulfide;Kromfax Solvent;NSC6289;Tedegyl;Thiodiethylene glycol;Thiodiglycol;b,b'-Dihydroxydiethyl sulfide;b,b'-Dihydroxyethyl sulfide;b-Thiodiglycol;
PSA 65.76000
LogP -0.29580

Synthetic route

: 75-21-8
oxirane

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With hydrogen sulfide at 20℃; Temperature;	99.5%
With hydrogen sulfide

: 60-24-2
2-hydroxyethanethiol

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With dihydrogen peroxide In ethanol; water at 20℃; for 0.0833333h; Green chemistry;	98%
With dihydrogen peroxide In ethanol at 20℃; for 0.5h; Green chemistry;	97%
With dihydrogen peroxide In ethanol at 20℃; for 1h; Catalytic behavior; Reagent/catalyst; Green chemistry; chemoselective reaction;	90%
With dihydrogen peroxide In neat (no solvent, solid phase) at 20℃; for 0.583333h; Catalytic behavior; Green chemistry;	76%
With dihydrogen peroxide In water at 20℃; for 0.1h; Rate constant; Mechanism; Thermodynamic data; ΔH(excit.), ΔS(excit.), stoichiometry, various pH, various concentrations;

: 96-49-1
[1,3]-dioxolan-2-one

: 60-24-2
2-hydroxyethanethiol

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
at 120 - 125℃;
With potassium carbonate In neat (no solvent) at 120℃; for 0.29h; Catalytic behavior; Temperature;

: 505-60-2
bis (2-chloroethyl) sulphide

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With water; zinc(II) oxide
With water In ethanol Kinetics;

: 60-24-2
2-hydroxyethanethiol

: 107-07-3
2-chloro-ethanol

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With sodium carbonate

: 107-07-3
2-chloro-ethanol

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With potassium hydrosulfide at 0℃;
With sodium hydrogensulfide at 25℃;
With sodium sulfide; water Darstellung;
With potassium sulfide; water
With sodium sulfide; water

: 75-21-8
oxirane

: 60-24-2
2-hydroxyethanethiol

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With triethylamine at 15℃; Rate constant; Mechanism; Thermodynamic data; other temperature, E(a);

: 693-30-1
mustard chlorohydrin

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With water In ethanol at 25℃; Rate constant; further solvents, var. water concentration; charge separation in the transition state;
With water

: 505-60-2
bis (2-chloroethyl) sulphide

A: 111-48-8
2,2'-thiobis-ethanol

B: 64036-92-6
bis-(2-hydroxy-ethyl)-[2-(2-hydroxy-ethylsulfanyl)-ethyl]-sulfonium

C: C12H28O4S3(2+)

Conditions

Conditions	Yield
In water Title compound not separated from byproducts;

...Expand

: 64036-92-6
bis-(2-hydroxy-ethyl)-[2-(2-hydroxy-ethylsulfanyl)-ethyl]-sulfonium

A: 111-48-8
2,2'-thiobis-ethanol

B: 693-30-1
mustard chlorohydrin

C: 505-60-2
bis (2-chloroethyl) sulphide

Conditions

Conditions	Yield
With hydrogenchloride In water Product distribution; Mechanism;	A 25.3 % Chromat. B 64.8 % Chromat. C 3.8 % Chromat.

...Expand

: C12H28O4S3(2+)

A: 505-29-3
1,4-Dithiane

B: 111-48-8
2,2'-thiobis-ethanol

C: 693-30-1
mustard chlorohydrin

D: 505-60-2
bis (2-chloroethyl) sulphide

Conditions

Conditions	Yield
With hydrogenchloride In water Product distribution; Mechanism;	A 11.6 % Chromat. B 15.1 % Chromat. C 49.3 % Chromat. D 20.2 % Chromat.

...Expand

: 95239-71-7
1-(p-Cyanophenyl)-3-triazene

A: 111-48-8
2,2'-thiobis-ethanol

B: 505-60-2
bis (2-chloroethyl) sulphide

C: N-

D: N-

E: 873-74-5
4-Aminobenzonitrile

Conditions

Conditions	Yield
With water at 37℃; Product distribution; Mechanism; pH 7.2, phosphate buffer; also with 1-(p-cyanophenyl)-3-triazene: deuterium distribution;

...Expand

: 182503-68-0
(S)-2-tert-Butoxycarbonylamino-3-{[2-(2-tert-butoxy-ethylsulfanyl)-ethoxy]-hydroxy-phosphoryloxy}-propionic acid tert-butyl ester

A: 111-48-8
2,2'-thiobis-ethanol

B: C3H6NO6P(2-)

Conditions

Conditions	Yield
With trifluoroacetic acid for 2h;

: (S)-3-{Benzyloxy-[2-(2-tert-butoxy-ethylsulfanyl)-ethoxy]-phosphoryloxy}-2-tert-butoxycarbonylamino-propionic acid tert-butyl ester

A: 111-48-8
2,2'-thiobis-ethanol

B: C3H6NO6P(2-)

Conditions

Conditions	Yield
With trifluoroacetic acid for 2h;

: 75-21-8
oxirane

: 7732-18-5
water

: 60-24-2
2-hydroxyethanethiol

: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
at 20℃; Kinetics; auch in Gegenwart von Bis-<2-hydroxy-aethyl>-sulfid, sowie in Bis-<2-hydroxy-aethyl-sulfid>;

...Expand

: 288-32-4
1H-imidazole

: 505-60-2
bis (2-chloroethyl) sulphide

A: 111-48-8
2,2'-thiobis-ethanol

B: 2-[(2-imidazolylethyl)thio]ethanol

C 8-thia-2-aza-5-azonia-spiro<4.5>deca-1,3-diene chloride: 8-thia-2-aza-5-azonia-spiro<4.5>deca-1,3-diene chloride

Conditions

Conditions	Yield
wss. Loesung vom pH 8.5;

...Expand

: 7732-18-5
water

: 7722-84-1
dihydrogen peroxide

: 60-24-2
2-hydroxyethanethiol

: 111-48-8
2,2'-thiobis-ethanol

...Expand

: 7732-18-5
water

: 7705-08-0
iron(III) chloride

: 60-24-2
2-hydroxyethanethiol

: 111-48-8
2,2'-thiobis-ethanol

...Expand

: 7732-18-5
water

: 60-24-2
2-hydroxyethanethiol

sodium hypobromite: sodium hypobromite

: 111-48-8
2,2'-thiobis-ethanol

...Expand

: 64-17-5
ethanol

: potassium hydrosulfide

: 107-07-3
2-chloro-ethanol

A: 111-48-8
2,2'-thiobis-ethanol

B: 1892-29-1
bis(2-hydroxyethyl) disulfide

C: 60-24-2
2-hydroxyethanethiol

D diethylene disulfide: diethylene disulfide

Conditions

Conditions	Yield
at 0℃;

...Expand

: 505-60-2
bis (2-chloroethyl) sulphide

A: 7647-01-0
hydrogenchloride

B: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
With water Hydrolysis;

: 505-60-2
bis (2-chloroethyl) sulphide

: 7732-18-5
water

zinc oxide: zinc oxide

: 111-48-8
2,2'-thiobis-ethanol

...Expand

: 505-60-2
bis (2-chloroethyl) sulphide

: 7732-18-5
water

A: 7647-01-0
hydrogenchloride

B: 111-48-8
2,2'-thiobis-ethanol

Conditions

Conditions	Yield
at 25℃;

...Expand

: 64-17-5
ethanol

: 505-60-2
bis (2-chloroethyl) sulphide

zinc: zinc

A: 111-48-8
2,2'-thiobis-ethanol

B: 41719-25-9
bis(2-ethoxyethyl)sulfide

C: 874529-11-0
2-(2-ethoxy-ethylsulfanyl)-ethanol

D: 14440-87-0
1,2-bis-(2-ethoxy-ethylsulfanyl)-ethane

Conditions

Conditions	Yield
anderen Produkte: Aethylendimercaptan; Diaethylendisulfid; Aethylen; Schwefelwasserstoff; Chlorwasserstoff; Diaethylsulfid; Aethylvinylsulfid;

...Expand

: 505-60-2
bis (2-chloroethyl) sulphide

water(2.25 mol): water(2.25 mol)

A: 111-48-8
2,2'-thiobis-ethanol

B 1-chloro-1-<2-hydroxy-ethyl>-<1,4>dithiane: 1-chloro-1-<2-hydroxy-ethyl>-<1,4>dithiane

...Expand

: 288-32-4
1H-imidazole

: 505-60-2
bis (2-chloroethyl) sulphide

A: 111-48-8
2,2'-thiobis-ethanol

B 2'-hydroxy-2--diethyl sulfide: 2'-hydroxy-2--diethyl sulfide

C 8-thia-2-aza-5-azonia-spiro<4.5>deca-1,3-diene chloride: 8-thia-2-aza-5-azonia-spiro<4.5>deca-1,3-diene chloride

Conditions

Conditions	Yield
bei pH 8;

...Expand

: 505-60-2
bis (2-chloroethyl) sulphide

: 63918-89-8
bis(2-chloroethylthioethyl)ether

: 7732-18-5
water

A: 111-48-8
2,2'-thiobis-ethanol

B bis-<2-hydroxy-ethyl>-<2-(2-hydroxy-ethylsulfanyl)-ethyl>-sulfonium chloride: bis-<2-hydroxy-ethyl>-<2-(2-hydroxy-ethylsulfanyl)-ethyl>-sulfonium chloride

...Expand

: 111-48-8
2,2'-thiobis-ethanol

: 2Al(3+)*2C5H7O2(1-)*4C3H7O(1-)=[Al(C5H7O2)(C3H7O)2]2

: 172702-72-6
[(C5H7O2)2Al(C3H7O)2AlO(CH2)2S(CH2)2O]2

Conditions

Conditions	Yield
In benzene reflux (3h, C3H7OH distd. off with benzene); solvent evapn.; elem. anal.;	100%

: 111-48-8
2,2'-thiobis-ethanol

: 6386-38-5
methyl 3-(4-hydroxy-3,5-di-tert-butyl)phenylpropanoate

: 41484-35-9
2-[2-[3-(4-hydroxy-3,5-di-tert-butyl-phenyl)propanoyloxy]ethylsulfanyl]ethyl 3-(4-hydroxy-3,5-di-tert-butyl-phenyl)propanoate

Conditions

Conditions	Yield
With alumina-supported potassium hydroxide at 120 - 160℃; for 0.5h; Catalytic behavior; Temperature; Inert atmosphere;	99.3%

: 111-48-8
2,2'-thiobis-ethanol

: 15980-15-1
1,4-Oxathiane

Conditions

Conditions	Yield
With copper(ll) bromide at 175℃; for 4h; Inert atmosphere; Sealed tube;	99%
With Trichlorbutylstannan for 0.16h;	42%
With sulfuric acid at 180℃;

: 111-48-8
2,2'-thiobis-ethanol

: 2Al(3+)*2C6H9O3(1-)*4C3H7O(1-)=[Al(C6H9O3)(C3H7O)2]2

: 172702-73-7
(C6H9O3)2Al(C3H7O)2AlO(CH2)2S(CH2)2O

Conditions

Conditions	Yield
In benzene reflux (3h, C3H7OH distd. off with benzene); solvent evapn.; elem. anal.;	99%

: 111-48-8
2,2'-thiobis-ethanol

: 1134503-88-0
germanium tetra-isopropoxide

: C10H22GeO4S

Conditions

Conditions	Yield
In benzene Reflux;	99%

: 111-48-8
2,2'-thiobis-ethanol

: antimony(III) isopropoxide

: {HO(CH2)2S(CH2)2O}Sb{O(CH2)2S(CH2)2O}

Conditions

Conditions	Yield
In benzene byproducts: isopropanol; anhydrous atmosphere; molar ratio 1 : 2, refluxing (7 h); solvent removal (reduced pressure, pptn.), recrystn. (DMSO/benzene); elem. anal.;	98%

: 111-48-8
2,2'-thiobis-ethanol

: 14165-55-0
tetraethoxygermanium

: C8H18GeO4S

Conditions

Conditions	Yield
In benzene for 6h; Reflux;	98%

: 111-48-8
2,2'-thiobis-ethanol

: 3085-45-8
bis(2-hydroxyethyl)sulfoxide

Conditions

Conditions	Yield
With dihydrogen peroxide for 72h; Ambient temperature;	97%
With dinitrogen tetraoxide; pyrographite In dichloromethane at 20℃; for 0.133333h;	95%
With N-(tert-butyl)-N-chloro-cyanamide In water; acetonitrile at 25℃;	92%

: 111-48-8
2,2'-thiobis-ethanol

: 14165-55-0
tetraethoxygermanium

: C8H16GeO4S2

Conditions

Conditions	Yield
In benzene Reflux;	97%

: 111-48-8
2,2'-thiobis-ethanol

: 57-11-4
stearic acid

: 4275-32-5
bis-(2-stearoyloxy-ethyl)-sulfide

Conditions

Conditions	Yield
With immobilized p-TsOH on activated carbon In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 2h; chemoselective reaction;	96%
at 160 - 180℃;

: 111-48-8
2,2'-thiobis-ethanol

: 16753-62-1
methylvinyldimethoxysilane

: 116393-20-5
2-methyl-2-vinyl-1,3-dioxa-6-thia-2-silacyclooctane

Conditions

Conditions	Yield
With sodium methylate In methanol; benzene for 8h; Heating;	95%

: 111-48-8
2,2'-thiobis-ethanol

: 5512-70-9
thiomorpholine-3-one

Conditions

Conditions	Yield
With pyridine; 4-AcNH-1-oxo-2,2,6,6-tetramethylpiperidinium tetrafluoroborate In dichloromethane at 20℃; for 3h;	95%

: 111-48-8
2,2'-thiobis-ethanol

: antimony(III) isopropoxide

: 135876-85-6
(i-Pr-O)Sb{O(CH2)2S(CH2)2O}

Conditions

Conditions	Yield
In benzene byproducts: isopropanol; anhydrous conditions; molar ratio 1:1, refluxing (4 h, distn. off of i-PrOH, crystn.); recrystn. (DMSO/benzene); elem. anal.;	95%

: 111-48-8
2,2'-thiobis-ethanol

: 544-63-8
n-tetradecanoic acid

: 68818-42-8
C32H62O4S

Conditions

Conditions	Yield
With immobilized p-TsOH on activated carbon In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 2h; chemoselective reaction;	95%

: 111-48-8
2,2'-thiobis-ethanol

: 2580-77-0
sulfonyldiethanol

Conditions

Conditions	Yield
With 5,10,15,20-tetrakis(pentafluorophenyl)-21H,23H-porphyrin iron(III) chloride; dihydrogen peroxide In ethanol at 20℃; for 0.25h;	94%
With water; ozone
With dihydrogen peroxide; acetone
With Perbenzoic acid; ethanol; chloroform
With dihydrogen peroxide; acetic acid

: 75-77-4
chloro-trimethyl-silane

: 111-48-8
2,2'-thiobis-ethanol

: 20486-03-7
bis(2-trimethylsiloxyethyl)sulfide

Conditions

Conditions	Yield
With urea at 20 - 25℃; for 6h;	93%
	76%
With triethylamine In toluene at 20℃; for 24h;

: 111-48-8
2,2'-thiobis-ethanol

A: 3570-55-6
3-thiapentan-1,5-dithiol

B: bis-mercaptodiethylsulphide

Conditions

Conditions	Yield
With hydrogenchloride; hydrazine hydrate; thiourea In 5,5-dimethyl-1,3-cyclohexadiene; water	A n/a B 93%

: 111-48-8
2,2'-thiobis-ethanol

: sodium tetrachloroaurate(III) dihydrate

: 1663-45-2
1,2-bis-(diphenylphosphino)ethane

: 18024-34-5
1,2-bis(diphenylphosphino)ethane digold(I) dichloride

Conditions

Conditions	Yield
In water; acetone Au-complex was reduced to Au(I) by thiodiglycol in aq. acetone, ligand in acetone was added dropwise over 5 min, stirred for 1 h; ppt. was filtered off, washed with H2O and acetone; elem. anal.;	93%

...Expand

: 143-07-7
lauric acid

: 111-48-8
2,2'-thiobis-ethanol

: 4275-31-4
bis-(2-lauroyloxy-ethyl)-sulfide

Conditions

Conditions	Yield
With immobilized p-TsOH on activated carbon In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 2h; Reagent/catalyst; Concentration; Solvent; chemoselective reaction;	92%
at 180℃;

: 111-48-8
2,2'-thiobis-ethanol

: 96-99-1
4-chloro-3-nitrobenzoate

: 2840-28-0
3-amino-4-chloro-benzoic acid

Conditions

Conditions	Yield
In methanol; water	92%

: 111-48-8
2,2'-thiobis-ethanol

: chloroauric acid

: 701-73-5
methyl N-phenyldithiocarbamate

: AuCl(C6H5NHC(S)SCH3)

Conditions

Conditions	Yield
In acetone dissolution of HAuCl4 in acetone, addn. of S(CH2CH2OH)2, reacting (30 min), addn. of soln. of dithio-compd. in acetone; crystn. (2 weeks, -33°C); elem. anal.;	91.3%

...Expand

: 111-48-8
2,2'-thiobis-ethanol

: 57-10-3
1-hexadecylcarboxylic acid

: 68818-43-9
C36H70O4S

Conditions

Conditions	Yield
With immobilized p-TsOH on activated carbon In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 2h; chemoselective reaction;	91%

: 111-48-8
2,2'-thiobis-ethanol

: 182496-55-5
tert-butylthiacalix[4]arene

: 827618-86-0
TIMEOUT: 5s

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In toluene at 20℃; for 1h; Mitsunobu reaction;	90%

: potassium cyanide

: 111-48-8
2,2'-thiobis-ethanol

: chloroauric acid

: 603-35-0
triphenylphosphine

: cyano(triphenylphosphine)gold(I)

Conditions

Conditions	Yield
In water byproducts: KCl; reduction of HAuCl4 with thiodiglycol at 0°C, followed by the phosphine addition; intermediate complex was washed several times with EtOH and then reacted with KCN; elem. anal.;	90%

...Expand

: 111-48-8
2,2'-thiobis-ethanol

: 105-58-8
Diethyl carbonate

: 500798-11-8
bis-(2-ethylcarbonate)ethyl sulfide

Conditions

Conditions	Yield
for 17h; Reflux;	90%

: 111-48-8
2,2'-thiobis-ethanol

: sodium tetrachloroaurate(III)*0.5H2O

: 983-80-2
cis-1,2-bis-(diphenylphosphino)ethene

: 102532-72-9
{Au(cis-bis(diphenylphosphino)ethylene)2}Cl

Conditions

Conditions	Yield
In water; acetone addn. of thiodiglycol to NaAuCl4 in H2O/Me2CO, then addn. of phosphine in Me2CO (molar ratio Au : phosphine = 1 : 3); elem. anal.;	88%

...Expand

: 111-48-8
2,2'-thiobis-ethanol

: cobalt(II) chloride hexahydrate

: 35872-09-4, 74779-08-1
dichlorobis(2,2'-thiodiethanol)cobalt(II)

Conditions

Conditions	Yield
In methanol under N2 atm. to soln. CoCl2*6H2O in MeOH soln. 2,2'-thiodiethanol in methanol was added, mixt. was stirred for 1 day; soln. was concd. in vacuo; Et2O vapor diffusion; elem. anal.;	87%

: 111-48-8
2,2'-thiobis-ethanol

A: 2580-77-0
sulfonyldiethanol

B: 87220-53-9
4,4-Dioxo-4λ6-[1,4]oxathian-2-one

Conditions

Conditions	Yield
With sodium bromite In water; acetic acid for 10h; Ambient temperature;	A 12% B 86%

2,2'-Thiodiethanol Consensus Reports

Reported in EPA TSCA Inventory.

2,2'-Thiodiethanol Specification

The β-Thiodiglycol, with the CAS registry number 111-48-8, is also known as 2,2'-Sulfanediyldiethanol. It belongs to the product category of Organics. Its EINECS registry number is 203-874-3. This chemical's molecular formula is C₄H₁₀O₂S and molecular weight is 122.19. What's more, its IUPAC name is called 2-(2-Hydroxyethylsulfanyl)ethanol. β-Thiodiglycol is a viscous, clear to pale-yellow liquid. It is used as a solvent in a variety of applications ranging from dyeing textiles to inks in some ballpoint pens. In chemical synthesis, the production is used as a building block for protection products, dispersants, fibers, plasticizers, rubber accelerators, pesticides, dyes, and various other organic chemicals. In the manufacture of polymers, this chemical is used as a chain transfer agent. As an antioxidant, it is used as an additive in lubricants.

Physical properties about β-Thiodiglycol are: (1)# of Rule of 5 Violations: 0; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 9.75; (5)ACD/KOC (pH 7.4): 9.75; (6)#H bond acceptors: 2; (7)#H bond donors: 2; (8)#Freely Rotating Bonds: 6; (9)Polar Surface Area: 65.76 Å²; (10)Index of Refraction: 1.523; (11)Molar Refractivity: 31.64 cm³; (12)Molar Volume: 103.5 cm³; (13)Surface Tension: 50 dyne/cm; (14)Density: 1.18 g/cm³; (15)Flash Point: 139.5 °C; (16)Enthalpy of Vaporization: 60.45 kJ/mol; (17)Boiling Point: 282 °C at 760 mmHg; (18)Vapour Pressure: 0.000407 mmHg at 25 °C.

Preparation of β-Thiodiglycol: this chemical can be prepared by Chlorohydrin with Sodium sulfide. This reaction needs reagent sulfuric acid at temperature of 90-95 °C.

2CH₂Cl-CH₂OH + Na₂S → (CH₂CH₂OH)₂S + 2NaCl

Uses of β-Thiodiglycol: it is used to produce other chemicals. For example, it can react with Methanol to get Bis-(2-methoxy-ethyl)-sulfane. The reaction occurs with reagent p-Toluenesulfonic acid monohydrate at temperature of 150 °C. The reaction time is 10 hours. The yield is 66 %.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin, eyes and respiratory system or other mucous membranes. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. And in case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: OCCSCCO
(2) InChI: InChI=1S/C4H10O2S/c5-1-3-7-4-2-6/h5-6H,1-4H2
(3) InChIKey: YODZTKMDCQEPHD-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	3960mg/kg (3960mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
mouse	LD50	subcutaneous	4gm/kg (4000mg/kg)	GASTROINTESTINAL: OTHER CHANGES LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE" ENDOCRINE: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rabbit	LD50	intravenous	3gm/kg (3000mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.
rabbit	LD50	skin	20mL/kg (20mL/kg)		Union Carbide Data Sheet. Vol. 11/3/1971,
rat	LD50	oral	6610mg/kg (6610mg/kg)		Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
rat	LD50	subcutaneous	4gm/kg (4000mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 1, 1948.

Product Name

2,2'-Thiodiethanol

Synthetic route

2,2'-Thiodiethanol Consensus Reports

2,2'-Thiodiethanol Specification

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