2,5-Dimethylfuran supplier

Name
2,5-Dimethylfuran
EINECS 210-914-3
CAS No. 625-86-5
Article Data164
CAS DataBase
Density 0.917 g/cm³
Solubility Slightly miscible with water. Miscible with ethanol and fats.
Melting Point -62 °C
Formula C₆H₈O
Boiling Point 93.089 °C at 760 mmHg
Molecular Weight 96.1289
Flash Point 29°F
Transport Information UN 1993 3/PG 2
Appearance clear colorless to amber liquid
Safety 16
Risk Codes 11
Molecular Structure
Hazard Symbols F
Synonyms Furan, 2,5-dimethyl-;2.5-Dimethyl furan;2,5-Dimthylfuran;
PSA 13.14000
LogP 1.89640

Synthetic route

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With hydrogen under 2250.23 Torr; for 15h;	100%
With CuZnCo-2.5 In ethanol at 200℃; for 0.5h; Temperature; Reagent/catalyst; Solvent; Autoclave;	99.8%
With hydrogen at 160℃; under 7500.75 Torr; for 1.5h; Catalytic behavior; Time; chemoselective reaction;	98.1%

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 625-86-5
2,5-dimethylfuran

B: 1333-74-0
hydrogen

Conditions

Conditions	Yield
With ethanol at 210℃; for 5h; Reagent/catalyst; Autoclave;	A 99% B n/a

: 110-13-4
2,5-hexanedione

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With MCM-36_M56 zeolite at 349.84℃; under 760.051 Torr; for 0.5h;	98%
With choline chloride; urea at 80℃; for 12h; Paal-Knorr Furan Synthesis;	95%
η-benzene-η-pentamethylcyclopentadienylrhodium(III) tetrafluoroborate at 200℃; for 5h; aldol condensation;	90%

: 1883-75-6
2,5-bis-(hydroxymethyl)furan

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With tetradecane; hydrogen In ethanol at 200℃; under 22502.3 Torr; for 15h; Reagent/catalyst; Temperature; Pressure;	97.6%
With formic acid; sulfuric acid; palladium on carbon In tetrahydrofuran for 15h; Reflux;
With formic acid; sulfuric acid; palladium on activated charcoal In tetrahydrofuran for 15h; Reflux;

: 620-02-0
5-Methylfurfural

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With hydrogen; pyrographite; N,N-dimethyl-formamide; palladium dichloride under 2585.81 Torr; for 1.75h;	96%
With methanol; Cu/Al2O3 at 240℃; for 6h; Reagent/catalyst; Sealed tube;	72.8%
With potassium tert-butylate; hydrazine hydrate In iso-butanol at 120℃; for 4h; Wolff-Kishner Reduction;	62%

: 18091-24-2
5-methyl-2-furfuryl acetate

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With methanol; sodium tetrahydroborate; nickel dichloride at 0℃; for 3h;	95%

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 534-22-5
2-methylfuran

B: 98-00-0
(2-furyl)methyl alcohol

C: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 180℃; under 11251.1 Torr; for 2h; Catalytic behavior;	A n/a B n/a C 93.4%

...Expand

: 1623-88-7
5-chloromethylfurfural

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen; N,N-dimethyl-formamide In toluene at 35 - 43℃; under 258.581 - 2585.81 Torr; Reagent/catalyst; Solvent; Pressure; Temperature;	93%
With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; palladium/alumina; hydrogen In toluene at 30 - 35℃; under 2828.7 - 3345.86 Torr; for 2h; Reagent/catalyst; Solvent;	84%
With palladium on activated charcoal; hydrogen

: 5426-09-5
7-oxanorborn-5-ene-2,3-dicarboxylic anhydride

: 74-88-4
methyl iodide

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With aluminum (III) chloride at 120℃; for 2h; Reagent/catalyst; Temperature;	93%

: 61973-96-4
N-(5-methyl-2-furanylmethylene)-aniline

A: 625-86-5
2,5-dimethylfuran

B: 62-53-3
aniline

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In diethyl ether under 1535.79 Torr; for 0.666667h; Solvent;	A n/a B 92%

: 69924-30-7
5-hydroxymethyl-tetrahydrofuran-2-carbaldehyde

A: 1003-38-9
2,5-dimethyltetrahydrofuran

B: 104-80-3, 1122-89-0, 2144-40-3, 81370-88-9, 81370-89-0
tetrahydrofuran-2,5-dimethanol

C: 625-86-5
2,5-dimethylfuran

D: 110-13-4
2,5-hexanedione

E: 37493-29-1
5-methyltetrahydro-2-furaldehyde

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 180℃; under 9000.9 Torr; for 4h; Catalytic behavior; Overall yield = 100 %;	A 1.4% B 3.6% C 91.5% D 3.2% E n/a
With hydrogen In 1,4-dioxane at 180℃; under 9000.9 Torr; for 4h; Catalytic behavior; Overall yield = 100 %;	A 9.5% B 4.9% C 80.1% D 3.4% E n/a

...Expand

: 116340-28-4
2,5-bis(trimethylsilyloxy)hexa-2,4-diene

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid at 140℃; for 3.5h;	90%

: 110-13-4
2,5-hexanedione

A: 625-86-5
2,5-dimethylfuran

B: 2758-18-1
3-Methyl-2-cyclopenten-1-one

Conditions

Conditions	Yield
Amberlite IR-120 at 180℃; for 12h;	A 89% B 0.2%
Amberlite IR-120 at 180℃; for 12h; Product distribution; various temperatures, also with Nafion-H;	A 89% B 0.2%
Nafion-H at 180℃; for 12h;	A 30% B 3%

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 1003-38-9
2,5-dimethyltetrahydrofuran

B: 625-86-5
2,5-dimethylfuran

C: 626-93-7
n-hexan-2-ol

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 180℃; under 11251.1 Torr; for 15h; Temperature; Sealed tube;	A n/a B 88.5% C n/a

...Expand

: 5076-10-8
2,5-bis(hydroxymethyl)furan diacetate

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With hydrogen; 2 wt% Pd/C In tetrahydrofuran at 90℃; under 7757.43 Torr; for 2h;	86%
With methanol; sodium tetrahydroborate; nickel dichloride at 0℃; for 3h;	67%
With palladium on carbon; hydrogen In tetrahydrofuran at 90℃; under 2585.81 Torr; for 4h;
With hydrogen; Pd/C under 25858.1 Torr; Product distribution / selectivity;

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 1003-38-9
2,5-dimethyltetrahydrofuran

B: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With isopropyl alcohol In decane at 160℃; under 15001.5 Torr; for 8h; Reagent/catalyst; Temperature; Solvent; Pressure; Autoclave; Inert atmosphere;	A 8% B 84%
With hydrogen In tetrahydrofuran at 220℃; under 11251.1 Torr; for 2.5h; Time;	A 6.4% B 67.5%
With rhodium on carbon; hydrogen; 1-butyl-3-methylimidazolium chloride In tetrahydrofuran; water at 220℃; under 37503.8 Torr; for 5h; Solvent; Reagent/catalyst; Autoclave;	A 20% B 47%

: 126080-78-2
2-(chloromethyl)-5-(dibutoxymethyl)furan

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen In pentane for 0.5h;	82%
With 5%-palladium/activated carbon; hydrogen In pentane under 1277.21 Torr; for 0.666667h; Solvent;	93 %Chromat.

: 1883-75-6
2,5-bis-(hydroxymethyl)furan

A: 625-86-5
2,5-dimethylfuran

B: 620-02-0
5-Methylfurfural

C: 823-82-5
2,5-diformylfurane

Conditions

Conditions	Yield
With iodine at 60℃; for 10h; Inert atmosphere; Sealed tube;	A 5% B 80% C 6%

...Expand

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 625-86-5
2,5-dimethylfuran

B: 620-02-0
5-Methylfurfural

C: 1883-75-6
2,5-bis-(hydroxymethyl)furan

D: C7H10O

E: 121709-55-5
2,2′-(1,2-ethanediyl)bis [5-methylfuran]

Conditions

Conditions	Yield
With hydrogen In tetrahydrofuran at 130℃; under 7500.75 Torr; for 24h; Pressure; Temperature; Reagent/catalyst; Time; Autoclave; High pressure;	A 76% B n/a C n/a D n/a E n/a

...Expand

: exo/endo-2,2-Dichlor-1,4-dimethyl-3-neopentyl-7-oxa-2-silabicyclo<2.2.1>hex-5-en

A: 625-86-5
2,5-dimethylfuran

B: 118853-33-1
(E)-1,1,3,3-Tetrachlor-2,4-dineopentyl-1,3-disilacyclobutan

C: 148728-63-6
3,3-Dichlor-4-trichlorsilyl-6,6-dimethyl-3-silahept-1-en

D: 2,2-Dichlor-4,7-dimethyl-3-neopentyl-1-oxa-2-silacyclohepta-4,6-dien

Conditions

Conditions	Yield
In neat (no solvent) at 170℃; for 72h; vacuum; Further byproducts given;	A n/a B n/a C n/a D 75%

...Expand

: (4-Fluoro-phenyl)-[1-(5-methyl-furan-2-yl)-meth-(E)-ylidene]-amine

A: 625-86-5
2,5-dimethylfuran

B: C12H16FNO

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen; acetic acid In N,N-dimethyl-formamide at 20℃; under 1535.79 Torr;	A 74% B n/a

: C16H19NO

A: 625-86-5
2,5-dimethylfuran

B: C16H25NO

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen; acetic acid In N,N-dimethyl-formamide at 20℃; under 1535.79 Torr;	A 73% B n/a

: C16H19NO

A: 625-86-5
2,5-dimethylfuran

B: 769-92-6
4-tert-Butylaniline

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen; acetic acid under 1535.79 Torr;	A 72% B n/a

: 3031-66-1
3-hexyn-2,5-diol

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tributylphosphine; perfluorinated resinsulfonic acid (Nafion-H type) at 130℃; for 5h;	71%

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 625-86-5
2,5-dimethylfuran

B: 620-02-0
5-Methylfurfural

Conditions

Conditions	Yield
With hydrogen; Al(OH)(2,2'-bipyridine-5,5'-dicarboxylic acid)0.81(PdCl2)0.48(OTf)0.38 at 150℃; under 15001.5 Torr; for 24h;	A 71% B 29%
With awaruite; hydrogen at 160℃; under 7500.75 Torr; for 2h; Catalytic behavior; Time; chemoselective reaction;	A 15.7% B 19.8%
With hydrogenchloride; hydrogen In tetrahydrofuran at 60℃; under 760.051 Torr; for 6h; Reagent/catalyst; Schlenk technique;	A 8 %Chromat. B 7 %Chromat.

: 69924-30-7
5-hydroxymethyl-tetrahydrofuran-2-carbaldehyde

A: 1003-38-9
2,5-dimethyltetrahydrofuran

B: 104-80-3, 1122-89-0, 2144-40-3, 81370-88-9, 81370-89-0
tetrahydrofuran-2,5-dimethanol

C: 625-86-5
2,5-dimethylfuran

D: 3857-25-8
2-hydroxymethyl-5-methylfuran

E: 37493-29-1
5-methyltetrahydro-2-furaldehyde

Conditions

Conditions	Yield
With hydrogen In 1,4-dioxane at 180℃; under 9000.9 Torr; for 4h; Catalytic behavior; Reagent/catalyst; Overall yield = 100 %;	A 25.4% B 3.1% C 66.4% D 2.8% E n/a

...Expand

: 57-48-7
D-Fructose

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With aluminum (III) chloride; phosphoric acid; 5 wt% ruthenium/carbon; sulfuric acid; hydrogen In N,N-dimethyl-formamide at 200℃; under 11251.1 Torr; for 12h; Reagent/catalyst; Autoclave;	66.3%
With palladium on activated charcoal; hydrogen; zinc(II) chloride In tetrahydrofuran; water at 150℃; under 6000.6 Torr; for 9.5h;	19%
Multi-step reaction with 2 steps 1: Amb-70; Sn-β / water; tetrahydrofuran; 2-methyltetrahydrofuran / 0.67 h / 130 °C 2: SnRu/C; hydrogen / water / 4 h / 200 °C View Scheme

: 110-00-9
furan

: 74-88-4
methyl iodide

: 625-86-5
2,5-dimethylfuran

Conditions

Conditions	Yield
With sulfuric acid at 80℃; for 10h; Reagent/catalyst; Temperature;	64%

: 67-47-0
5-hydroxymethyl-2-furfuraldehyde

A: 625-86-5
2,5-dimethylfuran

B: 3857-25-8
2-hydroxymethyl-5-methylfuran

Conditions

Conditions	Yield
With hydrogen In tetrahydrofuran at 220℃; under 11251.1 Torr; for 2h;	A 62.3% B 9.3%
With hydrogenchloride; palladium on activated charcoal; hydrogen In tetrahydrofuran at 60℃; under 760.051 Torr; for 12h; Reagent/catalyst; Schlenk technique;
With hydrogen In ethanol at 230℃; under 37503.8 Torr; for 6h;	A 85.9 %Chromat. B 10.6 %Chromat.

: 625-86-5
2,5-dimethylfuran

: 110-13-4
2,5-hexanedione

Conditions

Conditions	Yield
With water at 100℃; for 2h;	100%
With carbon dioxide In water at 150℃; under 30003 Torr; for 15h; Autoclave;	95%
With carbon dioxide In water at 150℃; under 30003 Torr; for 15h; Autoclave;	95%

: 625-86-5
2,5-dimethylfuran

: 3298-40-6
mesoxalate de methyle

: 89215-47-4
2-Hydroxy-2-(5-methyl-furan-2-ylmethyl)-malonic acid dimethyl ester

Conditions

Conditions	Yield
In dichloromethane at 20℃; under 6375510 Torr; for 24h;	100%
In dichloromethane at 25℃; under 7500600 Torr; for 20h;	80%
In dichloromethane at 25℃; under 7500600 Torr;	80%

: 625-86-5
2,5-dimethylfuran

: 130223-65-3
α-chloroacetophenone benzoylhydrazone

: 130223-66-4
1-benzoyl-4a,6-dimethyl-3-phenyl,1,4,4a,7a-tetrahydrofuro<2,3-e>pyridazine

Conditions

Conditions	Yield
With sodium carbonate In dichloromethane for 12h;	100%

: 625-86-5
2,5-dimethylfuran

: 762-42-5
dimethyl acetylenedicarboxylate

: 18063-93-9
dimethyl 1,4-dimethyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

Conditions

Conditions	Yield
In 1,4-dioxane at 103℃;	100%
In dichloromethane under 7500600 Torr; for 20h; Ambient temperature;	95%
In 1,4-dioxane at 101℃; for 17.5h;	81%

: 625-86-5
2,5-dimethylfuran

: 762-42-5
dimethyl acetylenedicarboxylate

: 18063-93-9
dimethyl 1,4-dimethyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

Conditions

Conditions	Yield
at 100℃; for 21h;	100%
at 100℃; for 2h; Sealed tube;	78%
In 1,4-dioxane at 100℃; for 24h; Diels-Alder reaction;
In toluene at 150℃; Diels-Alder reaction; Microwave irradiation;

: 625-86-5
2,5-dimethylfuran

: 45722-89-2
1,4-dimethyl-2,3,7-trioxa-bicyclo[2.2.1]hept-5-ene

Conditions

Conditions	Yield
With oxygen In chloroform at -60℃;	100%
With oxygen In dichloromethane Rate constant;
With oxygen In dichloromethane Rate constant; Mechanism; Irradiation; further furans and cyclopentadienes;

: 625-86-5
2,5-dimethylfuran

: 1391764-29-6
2,5-dimethoxyphenyl triflate

: 5,8-dimethoxy-1,4-dimethyl-1,4-epoxy-1,4-dihydronaphthalene

Conditions

Conditions	Yield
With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at -78 - 25℃;	100%

: 625-86-5
2,5-dimethylfuran

: sodium 2-(4-chlorophenyl)diazene-1-sulfonate

: 76-05-1
trifluoroacetic acid

: 1-(4-chlorophenyl)-3,6-dimethylpyridazin-1-ium trifluoroacetate

Conditions

Conditions	Yield
In acetonitrile at 20 - 40℃; for 0.583333h; Schlenk technique; Inert atmosphere;	100%

...Expand

: 625-86-5
2,5-dimethylfuran

: 5354-81-4
sodium 2-(4-methoxyphenyl)diazene-1-sulfonate

: 76-05-1
trifluoroacetic acid

: 1-(4-methoxyphenyl)-3,6-dimethylpyridazin-1-ium trifluoroacetate

Conditions

Conditions	Yield
In acetonitrile at 20 - 40℃; for 0.583333h; Schlenk technique; Inert atmosphere;	100%

...Expand

: 625-86-5
2,5-dimethylfuran

: 17559-81-8
(Z)-hex-3-ene-2,5-dione

Conditions

Conditions	Yield
With magnesium monoperoxyphthalate hexahydrate In ethanol; water for 0.25h; Ambient temperature;	99%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at -10 - 20℃;	99%
With monoperoxyphthalic acid magnesium salt hexahydrate In ethanol; water at 20℃; for 0.25h; Inert atmosphere;	99%

: 625-86-5
2,5-dimethylfuran

: 6262-42-6
1,2,3,3-tetrachlorocyclopropene

: 724423-64-7
2,3,4,4-tetrachloro-1,5-dimethyl-8-oxa-bicyclo-[3.2.1]octa-2,6-diene

Conditions

Conditions	Yield
In benzene at 80℃; Diels-Alder cycloaddition;	99%
In toluene for 16h; Diels-Alder Reaction; Heating / reflux;	95.9%
In toluene for 16h; Heating / reflux;

: 625-86-5
2,5-dimethylfuran

: 91-01-0
1,1-Diphenylmethanol

: 3-(diphenylmethyl)-2,5-dimethylfuran

Conditions

Conditions	Yield
With tin(IV) chloride; bis(1,5-cyclooctadiene)diiridium(I) dichloride at 90℃; for 0.166667h;	99%
With [Cp*Ir(SnCl3)2{SnCl2(H2O)2}] In 1,2-dichloro-ethane at 70℃; Schlenk technique; Inert atmosphere; regioselective reaction;	96%
With copper(ll) bromide In 1,2-dichloro-ethane at 85℃; for 3h; Friedel-Crafts Alkylation;	85%

: 625-86-5
2,5-dimethylfuran

: 73183-34-3
bis(pinacol)diborane

: 1025718-96-0
2-(2,5-dimethylfuran-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
Stage #1: bis(pinacol)diborane With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine In tert-butyl methyl ether Inert atmosphere; Stage #2: 2,5-dimethylfuran In tert-butyl methyl ether at 80℃; for 0.0333333h; Inert atmosphere; Microwave irradiation;	99%

: 625-86-5
2,5-dimethylfuran

: 6262-42-6
1,2,3,3-tetrachlorocyclopropene

: C9H8Cl4O

Conditions

Conditions	Yield
In toluene Diels-Alder Cycloaddition; Reflux;	99%

: 625-86-5
2,5-dimethylfuran

: 762-42-5
dimethyl acetylenedicarboxylate

: 24736-84-3
diethyl 1,4-dimethyl-7-oxabicyclo[2,2,1]hepta-2,5-diene-2,3-dicarboxylate

Conditions

Conditions	Yield
In 1,4-dioxane at 100℃; for 24h; Diels-Alder Cycloaddition; Inert atmosphere;	99%

: 625-86-5
2,5-dimethylfuran

: 89670-33-7, 221527-96-4, 1197054-73-1
ferrocenyl(2-methylphenyl)methanol

: 2-methyl-5-(2-(ferrocenyl)-2-(o-tolyl)ethyl)furan

Conditions

Conditions	Yield
With camphor-10-sulfonic acid In 1,2-dichloro-ethane at 20℃; chemospecific reaction;	99%

: 625-86-5
2,5-dimethylfuran

: 96735-23-8
benzo[1,4]dithiin-1,1,4,4-tetraoxide

: 97984-16-2
C14H14O5S2

Conditions

Conditions	Yield
In dichloromethane for 20h; Ambient temperature;	98%

: 625-86-5
2,5-dimethylfuran

: 23488-38-2
2,3,5,6-tetrabromo-p-xylene

: 75670-39-2
6,7-dibromo-1,4,5,8-tetramethyl-1,4-dihydronaphthlene-1,4-endoxide

Conditions

Conditions	Yield
With n-butyllithium In hexane; toluene at -78℃; for 2h;	98%

: 625-86-5
2,5-dimethylfuran

: 3005-27-4
3,4-dibromo-1-methyl-2,5-dihydropyrrole-2,5-dione

: 155793-98-9
2,6-dibromo-1,4,7-trimethyl-10-oxa-4-azatricyclo<5.2.1.02,6>dec-8-ene-3,5-dione

Conditions

Conditions	Yield
at 70℃; for 18h;	98%

: 625-86-5
2,5-dimethylfuran

: 62-53-3
aniline

: 83-24-9
2,5-dimethyl-1-phenyl-1H-pyrrole

Conditions

Conditions	Yield
With Hf/SBA-15(20) at 150℃; for 6h; Reagent/catalyst; Temperature; Inert atmosphere;	98%
With solid acid H form zeolite Y with 2.6 Si/Al catalyst In toluene at 150℃; under 3750.38 Torr; for 0.5h; Inert atmosphere;	93%
With Fe3O4atSiO2atCS-SO3H In methanol; water at 170℃; for 3h; Temperature; Solvent; Autoclave;	79.9 %Chromat.

: 625-86-5
2,5-dimethylfuran

: 624-48-6
dimethyl cis-but-2-ene-1,4-dioate

: (1S,2S,3R,4R)-1,4-Dimethyl-7-oxa-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid dimethyl ester

Conditions

Conditions	Yield
With hafnium tetrachloride In dichloromethane at -30℃; for 11h;	97%

: 625-86-5
2,5-dimethylfuran

: 74-85-1
ethene

: 106-42-3
para-xylene

Conditions

Conditions	Yield
With P-containing zeolite Beta In n-heptane at 250℃; under 46504.7 Torr; Reagent/catalyst; Diels-Alder Cycloaddition;	97%
With benzoic acid anhydride In acetic acid at 280℃; under 63006.3 Torr; for 8h; Pressure; Reagent/catalyst; Solvent; Temperature; Time;	92.3%
With copper(II) bis(trifluoromethanesulfonate) In tetrahydrofuran at 270℃; under 26892.4 - 82745.9 Torr; for 5h; Catalytic behavior; Reagent/catalyst; Solvent; Inert atmosphere;	91%

: 625-86-5
2,5-dimethylfuran

: 1427026-26-3
1-(4-methylbenzenesulfonyl)-4-(4-fluorobenzene)-1H-1,2,3-triazole

: 1427026-31-0
1-(4-(4-fluorophenyl)-2-methyl-1-tosyl-1H-pyrrol-3-yl)propan-2-one

Conditions

Conditions	Yield
With Rh2[(N-(4-dodecylphenyl)sulfonyl)-(S)-prolinate]4 In 1,2-dichloro-ethane at 70℃; for 6h; Inert atmosphere;	97%

: 625-86-5
2,5-dimethylfuran

: 14181-73-8
α-bromomethyl p-nitrophenyl ketoxime

: 4a,6-dimethyl-3-(p-nitrophenyl)-4a,7a-dihydro-4H-furo-[2,3-e][1,2]oxazine

Conditions

Conditions	Yield
With sodium carbonate In dichloromethane at 20℃; for 17.5h;	97%

: 625-86-5
2,5-dimethylfuran

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 4705-93-5
1,4-dihydro-1,4-dimethyl-1,4-epoxynaphthalene

Conditions

Conditions	Yield
With cesium fluoride In acetonitrile at 20℃; for 16h; Diels-Alder Cycloaddition;	97%

: 625-86-5
2,5-dimethylfuran

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 4705-93-5
1,4-dimethyl-1,4-dihydro-1,4-epoxynaphthalene

Conditions

Conditions	Yield
With cesium fluoride In acetonitrile at 20℃; for 16h; Diels-Alder Cycloaddition;	97%

2,5-Dimethylfuran Chemical Properties

Molecular Structure of 2,5-Dimethyl furane (CAS NO.625-86-5):

IUPAC Name: 2,5-Dimethylfuran
Molecular Formula: C₆H₈O
Molecular Weight: 96.13
EINECS: 210-914-3
Melting Point: -62 °C
Index of Refraction: 1.45
Molar Refractivity: 28.2 cm³
Molar Volume: 104.7 cm³
Surface Tension: 25.9 dyne/cm
Density: 0.917 g/cm³
Flash Point: 29 °F
Enthalpy of Vaporization: 31.91 kJ/mol
Boiling Point: 93.1 °C at 760 mmHg
Vapour Pressure: 57.1 mmHg at 25 °C
storage temp.: Flammables area
Classification Code: Mutation data
Appearance: clear colorless to amber liquid
Canonical SMILES: CC1=CC=C(O1)C
InChI: InChI=1S/C6H8O/c1-5-3-4-6(2)7-5/h3-4H,1-2H3
InChIKey: GSNUFIFRDBKVIE-UHFFFAOYSA-N
Product Categories: Furans; furnan Flavor; Building Blocks; Heterocyclic Building Blocks
Air & Water Reactions: Highly flammable, Insoluble in water

2,5-Dimethylfuran Uses

2,5-Dimethyl furane (CAS NO.625-86-5) is used as a pharmaceutical intermediate and potential biofuel and used for organic synthesis.

2,5-Dimethylfuran Toxicity Data With Reference

1.	dnr-bcs 190 µg/disc	DFSCDX Developments in Food Science. 13 (1986),353.
2.	cyt-ham:ovr 8 mmol/L	CALEDQ Cancer Letters (Shannon, Ireland). 13 (1981),89.
3.	ihl-rat LCLo:500 ppm/4H	JIHTAB Journal of Industrial Hygiene and Toxicology. 31 (1949),343.

2,5-Dimethylfuran Consensus Reports

Reported in EPA TSCA Inventory.

2,5-Dimethylfuran Safety Profile

Moderately toxic by inhalation. Mutation data reported. A very dangerous fire hazard when exposed to heat or flame; can react vigorously with oxidizing materials. Keep away from heat and open flame. To fight fire, use alcohol foam, foam, CO₂, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Information of 2,5-Dimethyl furane (CAS NO.625-86-5):
Hazard Codes: F, Harmful Xn
Risk Statements: 11-22
R11:Highly flammable.
R22:Harmful if swallowed.
Safety Statements: 16
S16:Keep away from sources of ignition.
RIDADR: UN 1993 3/PG 2
WGK Germany: 3
RTECS: LU0875000
F: 8
Hazard Note: Harmful/Flammable
HazardClass: 3
PackingGroup: II

2,5-Dimethylfuran Specification

2,5-Dimethyl furane (CAS NO.625-86-5), its Synonyms are 2,5-Dimethylfuran ; Furan, 2,5-dimethyl- ; 2.5-Dimethyl furan .

Product Name

2,5-Dimethylfuran

Synthetic route

2,5-Dimethylfuran Chemical Properties

2,5-Dimethylfuran Uses

2,5-Dimethylfuran Toxicity Data With Reference

2,5-Dimethylfuran Consensus Reports

2,5-Dimethylfuran Safety Profile

2,5-Dimethylfuran Specification

Related Products

Hot Products