2-Amino-4-ethylpyridine

The 2-Amino-4-ethylpyridine, with the CAS registry number 33252-32-3, is also known as (4-Ethylpyridin-2-yl)amine. It belongs to the product categories of Pharmacetical; Pyridine; Aromatics Compounds; Aromatics; Drug Analogues; Intermediates; Amines; Heterocycles. Its EINECS number is 251-430-2. This chemical's molecular formula is C₇H₁₀N₂ and molecular weight is 122.17. What's more, its systematic name is 4-Ethyl-2-pyridinamine. This chemical should be sealed and stored in a cool and dry place. Moreover, it should be protected from oxides. It should be ensured that the workshop is well ventilated or equipped with exhaust devices. This substance is an analogue of pirlimycin and an antibiotic.

Physical properties of 2-Amino-4-ethylpyridine are: (1)ACD/LogP: 1.403; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.32; (4)ACD/LogD (pH 7.4): 1.15; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 3.86; (7)ACD/KOC (pH 5.5): 2.62; (8)ACD/KOC (pH 7.4): 77.68; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 38.91 Å²; (13)Index of Refraction: 1.561; (14)Molar Refractivity: 38.129 cm³; (15)Molar Volume: 117.755 cm³; (16)Polarizability: 15.116×10^-24cm³; (17)Surface Tension: 44.3 dyne/cm; (18)Density: 1.037 g/cm³; (19)Flash Point: 123.479 °C; (20)Enthalpy of Vaporization: 47.913 kJ/mol; (21)Boiling Point: 242.153 °C at 760 mmHg; (22)Vapour Pressure: 0.03 mmHg at 25°C.

Preparation: this chemical can be prepared by 2-(2,5-dimethylpyrrol-1-yl)-4-ethylpyridine by heating. This reaction will need reagent H₂NOH·HCl and solvents ethanol, H₂O with the reaction time of 1 day. The yield is about 90%.

Uses of 2-Amino-4-ethylpyridine: it can be used to produce 1-ethyl-3-[5-(7-ethyl-imidazo[1,2-a]pyridin-2-yl)-2-hydroxy-phenyl]-urea at the ambient temperature. It will need solvent ethanol with the reaction time of 3.5 hours. The yield is about 59%.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)SMILES: n1ccc(cc1N)CC
(2)Std. InChI: InChI=1S/C7H10N2/c1-2-6-3-4-9-7(8)5-6/h3-5H,2H2,1H3,(H2,8,9)
(3)Std. InChIKey: SJWHILBZPGQBJE-UHFFFAOYSA-N