2-Amino-4-nitro anisidine supplier

Name
2-Amino-4-nitro anisidine
EINECS 202-770-5
CAS No. 99-59-2
Article Data40
CAS DataBase
Density 1.318 g/cm³
Solubility Slightly soluble in water: <0.01 g/100 mL at 19.5 °C
Melting Point 117-119 °C(lit.)
Formula C₇H₈N₂O₃
Boiling Point 351.794 °C at 760 mmHg
Molecular Weight 168.152
Flash Point 166.559 °C
Transport Information
Appearance orange to brown powder
Safety 26-36-45-36/37
Risk Codes 36/37/38-20/21/22
Molecular Structure
Hazard Symbols Xi,Xn
Synonyms o-Anisidine,5-nitro- (8CI);(2-Methoxy-5-nitrophenyl)amine;1-Amino-2-methoxy-5-nitrobenzene;1-Methoxy-2-amino-4-nitrobenzene;2-(Methyloxy)-5-nitroaniline;2-Amino-1-methoxy-4-nitrobenzene;2-Amino-4-nitroanisole;2-Methoxy-5-nitroaniline;2-Methoxy-5-nitrobenzenamine;3-Nitro-6-methoxyaniline;4-Nitro-2-aminoanisole;5-Nitro-2-methoxyaniline;5-Nitro-o-anisidine;Azoamine Scarlet K;NSC 5510;
PSA 81.07000
LogP 2.29000

2-Amino-4-nitro anisidine Chemical Properties

IUPAC Name: 2-Methoxy-5-nitroaniline
The molecular formula of 5-Nitro-o-anisidine (CAS NO.99-59-2) is C₇H₈N₂O₃.

The molecular weight of 5-Nitro-o-anisidine (CAS NO.99-59-2) is 168.150020.
Synonyms of 5-Nitro-o-anisidine (CAS NO.99-59-2): 1-Amino-2-methoxy-5-nitrobenzene ; 1-Methoxy-2-amino-4-nitrobenzene ; 2-Methoxy-5-nitro-anilin ; 2-Methoxy-5-nitrobenzamine ; 2-Methoxy-5-nitro-benzenamin
Product Categories: Intermediates of Dyes and Pigments
Stability: Stable, but may be moisture sensitive. Incompatible with water, acids, strong oxidizing agents, acid chlorides, acid anhydrides, chloroformates
Apperance: orange to brown powder
Melting Point: 117-119 °C
Density: 1.2068
Colour Index: 37130
Water Solubility: Slightly soluble
BRN: 879620
EINECS: 202-770-5

2-Amino-4-nitro anisidine Uses

5-Nitro-o-anisidine (CAS NO.99-59-2) is used as a dye, pigment and organic synthesis intermediates.

2-Amino-4-nitro anisidine Production

Derived from 2,4-Dinitrochlorobenzene by the reaction of methoxy and restore.

2-Amino-4-nitro anisidine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	oral	1060mg/kg (1060mg/kg)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
rabbit	LD50	oral	1gm/kg (1000mg/kg)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(3), Pg. 48, 1988.
rat	LD50	oral	2250mg/kg (2250mg/kg)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(3), Pg. 48, 1988.

2-Amino-4-nitro anisidine Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 ,1982,p. 133.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-127 ,1978. . Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. Community Right-To-Know List.

2-Amino-4-nitro anisidine Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.Safety information of 5-Nitro-o-anisidine (CAS NO.99-59-2):
Hazard Codes Irritant Xi,Xn
Risk Statements 36/37/38-20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-45-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany 2
RTECS BZ7175000
Hazard Note Irritant

Product Name

2-Amino-4-nitro anisidine