2-Aminoethanol hydrochloride supplier

Name
ETHANOLAMINE HYDROCHLORIDE
EINECS
CAS No. 2002-24-6
Article Data9
CAS DataBase
Density
Solubility almost transparency
Melting Point 82-84oC(lit.)
Formula C₂H₇NO•ClH
Boiling Point 170.9°C at 760 mmHg
Molecular Weight 97.5446
Flash Point 93.3°C
Transport Information
Appearance White or slightly beige agglomerating crystals
Safety Mildly toxic by subcutaneous route. When heated to decomposition it emits toxic vapors of NO_x, HCl, and Cl⁻.
Risk Codes R36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms MEA hydrochloride;Ethanolamine HCl;2-Aminoethanol hydrochloride;2-ethanolamine hydrochloride;monoethanolamine hydrochloride;Ethanolamine hydrochloride;Ethanolamine chloride;N-(2-hydroxyethyl)-ammonium chloride;Ethanol,2-amino-,hydrochloride;2-hydroxyethylamino hydrochloride;ethan-1-ol-2-amine hydrochloride;2-Hydroxyethylamine Hydrochloride;Colamine hydrochloride;Ethanol, 2-amino-, hydrochloride;
PSA 46.25000
LogP 0.43970

Synthetic route

: 141-43-5
ethanolamine

: 2002-24-6
2-amino-ethanol hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride for 6h;	100%
With hydrogenchloride In water at 40℃; for 0.333333h; pH=2; Concentration;	99%
With hydrogenchloride In water at 0 - 60℃; for 3h;	90%
With hydrogenchloride

: 625-48-9
2-nitro-1-ethanol

: 2002-24-6
2-amino-ethanol hydrochloride

Conditions

Conditions	Yield
Stage #1: 2-nitro-1-ethanol With C36H56Cl3CrN2O; magnesium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane In tetrahydrofuran at 60℃; for 24h; Inert atmosphere; Schlenk technique; Stage #2: With hydrogenchloride In tetrahydrofuran; water; ethyl acetate at 20℃;	85%

: 23213-96-9
ethyl 2,2,2-trichloroacetimidate

: 2002-24-6
2-amino-ethanol hydrochloride

Conditions

Conditions	Yield
Stage #1: ethyl 2,2,2-trichloroacetimidate With N-iodo-succinimide In 1,2-dichloro-ethane at 110℃; for 3h; Inert atmosphere; Sealed tube; Stage #2: With hydrogenchloride In tetrahydrofuran; water; 1,2-dichloro-ethane at 20℃; for 5h; Inert atmosphere; Sealed tube;	63%

: 1258431-65-0
1-(thien-2-yl)-3,4,4-trichloro-3-buten-1-one

: 141-43-5
ethanolamine

A: 1258431-70-7
4,4-dichloro-3-(2-hydroxyethylamino)-1-(thien-2-yl)-2-buten-1-one

B: 2002-24-6
2-amino-ethanol hydrochloride

Conditions

Conditions	Yield
In diethyl ether at 15℃; Reflux;	A 48% B n/a

...Expand

: 1258431-66-1
1-(4-hydroxyphenyl)-3,4,4-trichloro-3-buten-1-one

: 141-43-5
ethanolamine

A: 1258431-73-0
4,4-dichloro-3-(2-hydroxyethylamino)-1-(4-hydroxyphenyl)-2-buten-1-one

B: 2002-24-6
2-amino-ethanol hydrochloride

Conditions

Conditions	Yield
In diethyl ether at 15℃; Reflux;	A 20% B n/a

...Expand

: C44H36N4O12P2(2-)*C2H7NO*H(1+)

A: 2002-24-6
2-amino-ethanol hydrochloride

B: C44H36N4O12P2(2-)

Conditions

Conditions	Yield
In d(4)-methanol; water-d2 Equilibrium constant;

: 2002-24-6
2-amino-ethanol hydrochloride

: 870-24-6
2-chloroethanamine hydrochloride

Conditions

Conditions	Yield
With thionyl chloride In chloroform for 5h; Heating;	100%
With thionyl chloride In N-methyl-acetamide; water; benzene	98%
With thionyl chloride In toluene at 75℃; for 3h; Temperature; Concentration;	95%

: 2002-24-6
2-amino-ethanol hydrochloride

: sodium; (4-nitro-phenylsulfanyl)-acetate

: 105892-18-0
2-hydroxyethylammonium 4-nitrophenylsulfanylacetate

Conditions

Conditions	Yield
Stage #1: sodium; (4-nitro-phenylsulfanyl)-acetate for 1h; Reflux; Alkaline conditions; Stage #2: 2-amino-ethanol hydrochloride for 2h;	99.6%

: 2002-24-6
2-amino-ethanol hydrochloride

: 920-46-7
Methacryloyl chloride

: 2-aminoethylmethacrylate hydrochloride

Conditions

Conditions	Yield
In neat (no solvent) at 80℃; for 2h;	99%
In toluene at 110℃; for 3.5h;
With hydroquinone at 100℃;

4,5-dihydroxyornithine-N2 -[4'-n-octyloxy[1,1'-biphenyl]-4-carbonyl]pneumocandin B0: 4,5-dihydroxyornithine-N2 -[4'-n-octyloxy[1,1'-biphenyl]-4-carbonyl]pneumocandin B0

: 2002-24-6
2-amino-ethanol hydrochloride

: 75-05-8
acetonitrile

: 624-86-2
O-ethyl hydroxylamine

Conditions

Conditions	Yield
With camphor-10-sulfonic acid In 4,5-Dihydroxyomithine-N2[-4'-n-octyloxy[1,1'-biphenyl]-4-carbonyl]Pneumocandin B0; dimethyl sulfoxide	98%

...Expand

4,5-dihydroxyornithine-N2 -[4'-n-pentyloxy-[1,1':4',1"-terphenyl]-4-carbonyl]pneumocandin B0: 4,5-dihydroxyornithine-N2 -[4'-n-pentyloxy-[1,1':4',1"-terphenyl]-4-carbonyl]pneumocandin B0

: 2002-24-6
2-amino-ethanol hydrochloride

: 75-05-8
acetonitrile

: aminoethyl Ether

Conditions

Conditions	Yield
With camphor-10-sulfonic acid In 4,5-Dihydroxyomithine-N2 -[4'-n-pentyloxy-[1,1',4',1"-terphenyl]-4-carbonyl]Pneumocandin B0; dimethyl sulfoxide	98%

...Expand

: 116-11-0
2-Methoxypropene

: 2002-24-6
2-amino-ethanol hydrochloride

: 127090-71-5
2-[1-(2-aminoethoxy)-1-methylethoxy]ethylamine

Conditions

Conditions	Yield
Stage #1: 2-amino-ethanol hydrochloride With toluene-4-sulfonic acid In dimethyl sulfoxide; acetone Stage #2: 2-Methoxypropene at 35℃; under 760.051 Torr; Solvent; Temperature; Inert atmosphere;	97.6%
With polystyrene sulfonic acid In N,N-dimethyl-formamide at 25 - 35℃; for 5h; Temperature; Solvent; Inert atmosphere;	97.1%

: 7719-09-7
thionyl chloride

: 2002-24-6
2-amino-ethanol hydrochloride

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 870-24-6
2-chloroethanamine hydrochloride

Conditions

Conditions	Yield
In benzene	97%

...Expand

: 2-(4-(methoxycarbonyl)-5-methylthiophen-2-yl)benzoic acid

: 2002-24-6
2-amino-ethanol hydrochloride

: methyl 5-(2-((2-hydroxyethyl)carbamoyl)phenyl)-2-methylthiophene-3-carboxylate

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h;	96%

: 2002-24-6
2-amino-ethanol hydrochloride

: 107-06-2
1,2-dichloro-ethane

: di-β-aminoethyl oxalate dihydrochloride

Conditions

Conditions	Yield
With oxalic acid	95%

: 24424-99-5
di-tert-butyl dicarbonate

: 2002-24-6
2-amino-ethanol hydrochloride

: 26690-80-2
2-(N-tert-butoxycarbonylamino)ethanol

Conditions

Conditions	Yield
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃;	95%
With pyridine at 0℃; for 0.5h; Inert atmosphere;	90%

: 2002-24-6
2-amino-ethanol hydrochloride

: 3282-30-2
pivaloyl chloride

: 25632-56-8
2-(pivaloyloxy)ethan-1-aminium chloride

Conditions

Conditions	Yield
at 20 - 90℃; for 19h;	94%
at 90℃; for 4h;

: 2002-24-6
2-amino-ethanol hydrochloride

: 814-68-6
acryloyl chloride

: 2-aminoethyl acrylate hydrochloride

Conditions

Conditions	Yield
In neat (no solvent) at 80℃; for 2h;	92%

: 64670-84-4
1-nitro-9-phenoxyacridine

: 2002-24-6
2-amino-ethanol hydrochloride

: 77280-93-4
1-nitro-9-(2-hydroxyethylamino)-acridine hydrochloride

: 1-nitro-9-hydroxyethylaminoacridine

Conditions

Conditions	Yield
With hydrogenchloride In phenol	91%

...Expand

: 2002-24-6
2-amino-ethanol hydrochloride

: 102862-46-4
3-p-Tolyl-oxirane-2,2-dicarbonitrile

: 103807-60-9
2-Chloro-N-(2-hydroxy-ethyl)-2-p-tolyl-acetamide

Conditions

Conditions	Yield
In acetonitrile for 1h; Heating;	90%

: 2002-24-6
2-amino-ethanol hydrochloride

: 473807-32-8
5-{3-dimethylamino-1-[2-(dimethylamino)vinyl]prop-2-enylidene}-3-methyl-2-thioxo-1,3-thiazolidin-4-one

: 5-[1-(2-hydroxyethyl)pyridin-4(1H)-ylidene]-3-methyl-2-thioxo-1,3-thiazolidin-4-one

Conditions

Conditions	Yield
In ethanol for 1h; Heating;	90%

: 14283-99-9, 36186-03-5
bis(N-salicylaldimino)nickel(II)

: 2002-24-6
2-amino-ethanol hydrochloride

A: 92280-97-2, 137736-86-8
Ni(C6H4(O)CHNC2H4OH)2

B: ammonium chloride

Conditions

Conditions	Yield
In methanol stirring the soln. for 30 min between room temp. and 60°C, pptn.; filtration, washing with water, recrystn. from acetone;	A 90% B n/a

...Expand

: 2002-24-6
2-amino-ethanol hydrochloride

: 1493-27-2
ortho-nitrofluorobenzene

: 4926-55-0
2-[(2-nitrophenyl)amino]ethanol

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 82℃; for 6h;	89%

: 2002-24-6
2-amino-ethanol hydrochloride

: 81054-77-5
Triethylammonium-

: 2-<α,α-Bis-(2-hydroethylamino)-methyliden>-indan-1,3-dion

Conditions

Conditions	Yield
With triethylamine In methanol	87%

: 2002-24-6
2-amino-ethanol hydrochloride

: 75-36-5
acetyl chloride

: 20739-39-3
1-acetoxy-2-aminoethane hydrochloride

Conditions

Conditions	Yield
In acetic acid at 20℃;	86.25%

: 7-Methoxy-4-methyl-1-nitro-9-phenoxyacridine

: 2002-24-6
2-amino-ethanol hydrochloride

: 9-(2'-hydroxyethylamino)-7-methoxy-4-methyl-1-nitroacridine monohydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In phenol	86%
With hydrogenchloride In phenol	86%
With hydrogenchloride In phenol	86%

: 110-86-1
pyridine

: 2002-24-6
2-amino-ethanol hydrochloride

: 45705-58-6
N-(2-Aminoethyl)pyridinium chloride

Conditions

Conditions	Yield
In water for 18h; Heating;	85%

: 9-phenoxy-4-methyl-1-niroacridine

: 2002-24-6
2-amino-ethanol hydrochloride

: 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine monohydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In phenol	84%
With hydrogenchloride In phenol	84%
With hydrogenchloride In phenol	84%

: 2002-24-6
2-amino-ethanol hydrochloride

: 102699-82-1
(E)-1-Chloro-3-methyl-oct-2-en-6-yne

: 102699-83-2
2-<(3'-methyl-2'-octen-6'-ynyl)amino>ethanol

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 65℃; for 12h;	83%

: 111585-55-8
7-methoxy-1-nitro-9-phenoxy-acridine

: 2002-24-6
2-amino-ethanol hydrochloride

: 9-(2'-hydroxyethylamino)-7-methoxy-1-nitroacridine monohydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In phenol	83%
With hydrogenchloride In phenol	83%
With hydrogenchloride In phenol	83%

: 2002-24-6
2-amino-ethanol hydrochloride

: Vancomycin hydrochloride

: C68H80Cl2N10O24

Conditions

Conditions	Yield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide; N,N-dimethyl-formamide for 7h; Ambient temperature;	80%

: 355384-71-3
4-methoxy-1-nitro-9-phenoxy-acridine

: 2002-24-6
2-amino-ethanol hydrochloride

: 9-(2'-hydroxyethylamino)-4-methoxy-1-nitroacridine monohydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In phenol	77%

: 355384-71-3
4-methoxy-1-nitro-9-phenoxy-acridine

: 2002-24-6
2-amino-ethanol hydrochloride

A: 1-nitro-9-hydroxyethylaminoacridine

B: 9-(2'-hydroxyethylamino)-4-methoxy-1-nitroacridine monohydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In phenol	A 77% B n/a

...Expand

: 2002-24-6
2-amino-ethanol hydrochloride

: 108-24-7
acetic anhydride

: 20739-39-3
1-acetoxy-2-aminoethane hydrochloride

Conditions

Conditions	Yield
at 80℃; for 2h;	75%

2-Aminoethanol hydrochloride Chemical Properties

Empirical Formula: C₂H₈ClNO
Molecular Weight: 97.544
Flash Point: 93.3 °C
Enthalpy of Vaporization: 47.43 kJ/mol
Boiling Point: 170.9 °C at 760 mmHg
Vapour Pressure: 0.458 mmHg at 25 °C
EINECS: 217-900-6
storage temp.: Store at RT.
Sensitive: Hygroscopic
Melting point: 82-84 °C(lit.)
Appearance: White or slightly beige agglomerating crystals
Product Categories of Ethanolamine hydrochloride (CAS NO.2002-24-6): omega-Aminoalkanols;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
Structure of Ethanolamine hydrochloride (CAS NO.2002-24-6):

IUPAC Name: 2-Aminoethanol hydrochloride
Canonical SMILES: C(CO)N.Cl
InChI: InChI=1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H
InChIKey: PMUNIMVZCACZBB-UHFFFAOYSA-N

2-Aminoethanol hydrochloride Toxicity Data With Reference

scu-mus LD50:4053 mg/kg

ARZNAD Arzneimittel-Forschung. Drug Research. 4 (1954),649.

Ethanolamine hydrochloride (CAS NO.2002-24-6) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.

2-Aminoethanol hydrochloride Consensus Reports

Reported in EPA TSCA Inventory.

2-Aminoethanol hydrochloride Safety Profile

Mildly toxic by subcutaneous route. When heated to decomposition it emits toxic vapors of NO_x, HCl, and Cl⁻.

Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.

2-Aminoethanol hydrochloride Specification

Ethanolamine hydrochloride ,its cas register number is 2002-24-6. It also can be called Ethanolamine HCl ; Ethanol, 2-amino-, hydrochloride ; Monoethanolamine hydrochloride ; and 2-Aminoethanol hydrochloride . It is hazardous,so the first aid measures and others should be known. Such as: When on the skin: first,should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly,Get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.Notes to physician: Treat supportively and symptomatically.
In addition, Ethanolamine hydrochloride (CAS NO.2002-24-6) is not compatible with strong oxidizing agents, bases, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Product Name

ETHANOLAMINE HYDROCHLORIDE

Synthetic route

2-Aminoethanol hydrochloride Chemical Properties

2-Aminoethanol hydrochloride Toxicity Data With Reference

2-Aminoethanol hydrochloride Consensus Reports

2-Aminoethanol hydrochloride Safety Profile

2-Aminoethanol hydrochloride Specification

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