Analytical Methods: | | For occupational chemical analysis use NIOSH: Ethylene Chlorohydrin, 2513.
Risk Codes
R26/27/28
Molecular Structure
Hazard Symbols
Synonyms
1-Chloro-2-hydroxyethane;2-Chloro-1-ethanol; 2-Chloro-1-hydroxyethane; 2-Chloroethanol; 2-Chloroethylalcohol; 2-Hydroxyethyl chloride; Chloroethanol; Ethene chlorohydrin;Ethylchlorohydrin; Ethylene chlorhydrin; Ethylene chlorohydrin; Glycolchlorohydrin; Glycol monochlorohydrin; NSC 122289; b-Chloroethanol; b-Chloroethyl alcohol; b-Hydroxyethyl chloride
PSA
20.23000
LogP
0.21750
2-Chloroethanol Chemical PropertiesMF: C2H5ClO MW: 80.51 EINECS: 203-459-7 ETHYLENE CHLOROHYDRIN,it's melting point is about -63 °C ,boiling point is 129 °C(lit.),density is 1.201 g/mL at 25 °C(lit.).It is colorless liquid with a pleasant ether-like odor. It is miscible with water. 2-Chloroethanol UsesETHYLENE CHLOROHYDRIN is a building block in the production of pharmaceuticals, biocides and plasticizers. It is also used for manufacture of thiodiglycol. It is a solvent for cellulose acetate and ethyl cellulose, textile printing dyes, extraction of pine lignin, in dewaxing, refining of rosin, and the cleaning of machines. Several dyes are prepared by the alkylation of aniline derivatives with chloroethanol. 2-Chloroethanol ProductionETHYLENE CHLOROHYDRIN is produced by treating ethylene with hypochlorous acid: CH2=CH2 + HOCl → HOCH2CH2Cl 2-Chloroethanol Toxicity Data With Reference1. | | skn-rbt 200 mg/2H MLD | | TXAPA9 Toxicology and Applied Pharmacology. 16 (1970),382. | 2. | | eye-rbt 2 mg SEV | | AJOPAA American Journal of Ophthalmology. 29 (1946),1363. | 3. | | eye-rbt 33 mg MOD | | TXAPA9 Toxicology and Applied Pharmacology. 16 (1970),382. | 4. | | eye-rbt 9 mg/6H MOD | | BUYRAI Bulletin of Parenteral Drug Association. 31 (1977),25. | 5. | | sln-asn 74,500 µmol/L | | MUREAV Mutation Research. 138 (1984),33. | 6. | | oms-rat:lvr 12 g/L | | JACTDZ Journal of the American College of Toxicology. 1 (3)(1982),37. | 7. | | ihl-man LCLo:305 ppm/2H | | JIHTAB Journal of Industrial Hygiene and Toxicology. 26 (1944),277. | 8. | | orl-rat LD50:71 mg/kg | | HYSAAV Hygiene and Sanitation: English Translation of Gigiena Sanitariya. 36 (1971),376. | 9. | | ihl-rat LC50:290 mg/m3 | | HYSAAV Hygiene and Sanitation: English Translation of Gigiena Sanitariya. 26 (1971),376. | 10. | | ipr-rat LD50:58 mg/kg | | TXAPA9 Toxicology and Applied Pharmacology. 21 (1972),454. |
RTECS :KK0875000 |
ETHYLENE CHLOROHYDRIN is toxic with an LD50 of 89 mg/kg in rats. 2-Chloroethanol Consensus ReportsNTP Carcinogenesis Studies (dermal); No Evidence: mouse, rat NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-275 ,1985. ; Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List. 2-Chloroethanol Safety ProfileA poison by ingestion, inhalation, skin contact, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by inhalation. It can affect the nervous system, liver, spleen, and lungs. An experimental teratogen. Mutation data reported. A severe eye and mild skin irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, CO 2, dry chemical. Violent reaction with chlorosulfonic acid, ethylene diamine, sodium hydroxide. Reacts with water or steam to produce toxic and corrosive fumes. Potentially violent reaction with oxidizing materials. When heated to decomposition it emits highly toxic fumes of Cl − and phosgene. See also CHLORINATED HYDROCARBONS, ALIPHATIC. |
Like most organochlorine compounds, ETHYLENE CHLOROHYDRIN combusts to yield hydrogen chloride and phosgene. Hazard Codes: T+,T,F Risk Statements : 26/27/28-39/23/24/25-11 Safety Statements : 28-45-7/9-28A-36/37-16 RIDADR :UN 1135 6.1/PG 1 WGK Germany 3
2-Chloroethanol Standards and RecommendationsOSHA PEL: CL 1 ppm (skin) ACGIH TLV: CL 1 ppm (skin); Not Classifiable as a Human Carcinogen DFG MAK: 1 ppm (3.3 mg/m2) DOT Classification: 6.1; Label: Poison 2-Chloroethanol Analytical MethodsFor occupational chemical analysis use NIOSH: Ethylene Chlorohydrin, 2513. 2-Chloroethanol Specification Other names of ETHYLENE CHLOROHYDRIN :2-chloroethyl alcohol, ethylene chlorohydrin, 2-chloro-1-ethanol, 2-monochloroethanol,glycol chlorohydrin, 2-hydroxyethyl chloride, β-hydroxyethyl chloride, β-chloroethanol,chloroethanol,ethylchlorhydrin, δ-chloroethanol, ethylene chlorohydrin, glycol monochlorohydrin.
Related Products
Hot Products
|