2-Deoxy-D-glucose supplier

Name
2-Deoxy-D-glucose
EINECS 205-823-0
CAS No. 154-17-6
Article Data24
CAS DataBase
Density 1.533 g/cm³
Solubility water: 50 mg/mL, clear, colorless to faintly yellow
Melting Point 146-147 °C(lit.)
Formula C₆H₁₂O₅
Boiling Point 411 °C at 760 mmHg
Molecular Weight 164.158
Flash Point 202.3 °C
Transport Information
Appearance white to light yellow crystal powder
Safety 24/25-37/39-36-26
Risk Codes 20/21/22-36/37/38
Molecular Structure
Hazard Symbols Xn,Xi
Synonyms D-Glucose, 2-deoxy-;Deoxyglucose;2-DG;2-Deoxy-D-arabino-hexose;
PSA 97.99000
LogP -2.34960

2-Deoxy-D-glucose Chemical Properties

Molecular structure of 2-Deoxy-D-glucose (CAS NO.154-17-6) is:

Product Name: 2-Deoxy-D-glucose
CAS Registry Number: 154-17-6
IUPAC Name: (4R,5S,6R)-6-(hydroxymethyl)oxane-2,4,5-triol
Molecular Weight: 164.15648 [g/mol]
Molecular Formula: C₆H₁₂O₅
XLogP3-AA: -1.6
H-Bond Donor: 4
H-Bond Acceptor: 5
EINECS: 205-823-0
Melting Point: 146-147 °C(lit.)
Refractive index: 46.5 ° (C=1, H₂O)
Storage temp.: 0-6°C
Solubility: H₂O: 50 mg/mL, clear, colorless to faintly yellow
Surface Tension: 66.8 dyne/cm
Density: 1.533 g/cm³
Flash Point: 202.3 °C
Enthalpy of Vaporization: 76.65 kJ/mol
Boiling Point: 411 °C at 760 mmHg
Vapour Pressure: 1.8E-08 mmHg at 25°C
Product Categories: Pharmaceutical Raw Materials;chiral;Biochemistry;Deoxysugars;Glucose;Sugars;Carbohydrates & Derivatives

2-Deoxy-D-glucose Uses

2-Deoxy-D-glucose (CAS NO.154-17-6) has been used as a targeted optical imaging agent for fluorescent in vivo imaging. And it is a glucose antimetabolite, inhibiting glycolysis, it is a widely used research tool to study glucose-dependent or -mediated reactions.

2-Deoxy-D-glucose Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	intraperitoneal	2gm/kg (2000mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 17, Pg. 814, 1965.
rat	LD50	subcutaneous	250mg/kg (250mg/kg)		Annales Pharmaceutiques Francaises. Vol. 39, Pg. 327, 1981.

2-Deoxy-D-glucose Consensus Reports

Reported in EPA TSCA Inventory.

2-Deoxy-D-glucose Safety Profile

Poison by subcutaneous route. Moderately toxic by intraperitoneal route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes.
Hazard Codes: Harmful Xn,Xi
Risk Statements: 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-37/39-36-26
S24/25:Avoid contact with skin and eyes.
S37/39:Wear suitable gloves and eye/face protection.
S36:Wear suitable protective clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: MQ3325000
F: 3-10

2-Deoxy-D-glucose Specification

2-Deoxy-D-glucose , its cas register number is . It also can be called Deoxyglucose ; 2-DG ; 2-Deoxy-D-arabino-hexose ; 2-Deoxy-D-glucose ; 2-Deoxy-D-mannose ; 2-Desoxy-D-glucose ; D-2-Deoxyglucose ; D-Arabino-hexose, 2-deoxy- ; D-Glucose, 2-deoxy- .It is a white to light yellow crystal powder.It is uptaken by the glucose transporters of the cell.

Product Name

2-Deoxy-D-glucose