2-Hydroxy-6-aminopurine supplier

Name
6-Amino-3,7-dihydro-2H-purin-2-one
EINECS 222-157-6
CAS No. 3373-53-3
Article Data24
CAS DataBase
Density 2.19 g/cm³
Solubility slightly soluble in water
Melting Point 300 °C
Formula C₅H₅N₅O
Boiling Point 273.11°C (rough estimate)
Molecular Weight 151.128
Flash Point
Transport Information
Appearance white to light yellow crystal powder
Safety 24/25
Risk Codes 22
Molecular Structure
Hazard Symbols Xn
Synonyms 2H-Purin-2-one,6-amino-1,3-dihydro- (9CI);Isoguanine (6CI,7CI,8CI);2-Hydroxyadenine;2-Oxoadenine;2-Oxyadenine;6-Amino-2-hydroxypurine;Guanopterin;NSC 241501;
PSA 100.71000
LogP 0.22190

Synthetic route

: 1198-83-0
2-(methylthio)-7H-purin-6-amine

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With ethanol; dihydrogen peroxide
Multi-step reaction with 2 steps 1: chlorine; H2O 2: aq. NaOH solution View Scheme

: 22715-34-0
4,5,6-triamino-1H-pyrimidin-2-one

: 77287-34-4, 77287-35-5, 60100-09-6
formamide

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With formic acid at 160℃;

: 7357-53-1
2-methanesulfonyl-7(9)H-purin-6-ylamine

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With sodium hydroxide

: 1839-18-5
6-Amino-2-chlorpurin

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With hydrogenchloride

5-amino-1(3)H-imidazole-4-carboxamidine dihydrochloride: 5-amino-1(3)H-imidazole-4-carboxamidine dihydrochloride

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With urea at 180℃;
With sodium hydroxide

8-chloro-2-ethoxy-6-amino-purine: 8-chloro-2-ethoxy-6-amino-purine

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With phosphonium iodide; hydrogen iodide at 30 - 40℃;

crotonoside: crotonoside

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
With sulfuric acid Hydrogenation;

: 2914-09-2
2,8-dichloro-7(9)H-purin-6-ylamine

: 3373-53-3
isoguanine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: palladium/BaSO4; aq. NaOH solution 2: aqueous HCl View Scheme

: 3373-53-3
isoguanine

: 69-89-6
xanthin

Conditions

Conditions	Yield
With genes from Klebsiella pneumoniae subsp. pneumoniae In aq. buffer at 30℃; pH=7.5; Kinetics; Temperature; Reagent/catalyst; Enzymatic reaction;

: 3373-53-3
isoguanine

: 6-amino-2-oxo-1H,7H-purin-3-ium chloride

Conditions

Conditions	Yield
With hydrogenchloride In water

: 3373-53-3
isoguanine

A: 1,N6-etheno-N9β-D-ribofuranosylisoguanosine

B: 1,N6-etheno-N7β-D-ribofuranosylisoguanosine

C: 1,N6-etheno-N6β-D-ribofuranosylisoguanosine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride; sodium hydrogencarbonate / water / pH Ca. 2 2: ammonium hydroxide; calf spleen purine-nucleoside phosphorylase wild type / aq. buffer / 72 h / 30 °C / pH 7 / Enzymatic reaction View Scheme

...Expand

: 3373-53-3
isoguanine

: 1,N6-etheno-N6β-D-ribofuranosylisoguanosine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: hydrogenchloride; sodium hydrogencarbonate / water / pH Ca. 2 2: ammonium hydroxide; calf spleen purine-nucleoside phosphorylase-N243D / aq. buffer / 72 h / 30 °C / pH 7 / Enzymatic reaction View Scheme

: 107-20-0
2-chloroethanal

: 3373-53-3
isoguanine

: 1,5,9-dihydro-9-oximidazo[1,2-a]purine

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydrogencarbonate In water pH=Ca. 2;

2-Hydroxy-6-aminopurine Chemical Properties

IUPAC Name: 6-Amino-1,7-dihydropurin-2-one
CAS: 3373-53-3
Formula: C₅H₅N₅O
Molecular Structure of 6-Amino-1,7-dihydropurin-2-one (3373-53-3):

Molecular Weight: 151.13
Melting Point: 300 °C
Water Solubility: 1e+006(mg/L) at 25°C
Index of Refraction: 2.047
Molar Refractivity: 35.46 cm³
Molar Volume: 68.8 cm³
Polarizability: 14.06 10^-24cm³
Surface Tension: 124 dyne/cm
Density: 2.19 g/cm³
Appearance: white to light yellow crystal powder
The classification of 6-Amino-1,7-dihydropurin-2-one (3373-53-3) are purine;nucleotides and nucleosides;purines;biochemistry;nucleobases and their analogs;nucleosides, nucleotides & related
reagents;nucleic acids;bases & related reagents;intermediates & fine chemicals;nucleotides;pharmaceuticals.

2-Hydroxy-6-aminopurine Safety Profile

Safety statements about 6-Amino-1,7-dihydropurin-2-one (3373-53-3):
S24/25: Avoid contact with skin and eyes.

2-Hydroxy-6-aminopurine Specification

The chemical synonyms of 6-Amino-1,7-dihydropurin-2-one (3373-53-3) are 2-Hydroxy-6-aminopurine ; 6-Amino-1,3-dihydro-2h-purin-2-one ; Isoguanine ; 6-Amino-3,7-dihydro-2h-purin-2-one ; 6-Amino-1,7-dihydropurin-2-one .
The product of 6-Amino-1,7-dihydropurin-2-one (3373-53-3) can be used a nucleotide base as immunostimulator agent.
Handling and Storage of 6-amino-1,7-dihydropurin-2-one (3373-53-3): Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store in a cool, dry place. Store in a tightly closed container. Personal protective equipment: Wear chemical splash goggles.Wear appropriate protective gloves to prevent skin exposure and wear appropriate protective clothing to prevent skin exposure. Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.

Product Name

6-Amino-3,7-dihydro-2H-purin-2-one

Synthetic route

2-Hydroxy-6-aminopurine Chemical Properties

2-Hydroxy-6-aminopurine Safety Profile

2-Hydroxy-6-aminopurine Specification

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