2-Naphthyl acrylate supplier | CasNO.52684-34-1

Name
2-Naphthyl acrylate
EINECS
CAS No. 52684-34-1
Article Data6
CAS DataBase
Density 1.147 g/cm³
Solubility
Melting Point 38-42 °C
Formula C₁₃H₁₀O₂
Boiling Point 345.426 °C at 760 mmHg
Molecular Weight 198.221
Flash Point 143.685 °C
Transport Information
Appearance
Safety 26
Risk Codes 36
Molecular Structure
Hazard Symbols Xi
Synonyms 2-Naphthyl acrylate;
PSA 26.30000
LogP 2.93120

Synthetic route

: 79-10-7
acrylic acid

: 135-19-3
β-naphthol

: 52684-34-1
2-naphthyl acrylate

Conditions

Conditions	Yield
With magnesium hydroxide; di-tert-butyl dicarbonate; lithium carbonate at 25℃; for 24h; Reagent/catalyst;	95%

: 814-68-6
acryloyl chloride

: 135-19-3
β-naphthol

: 52684-34-1
2-naphthyl acrylate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; Inert atmosphere;	82%
With triethylamine In acetone at 20℃; for 0.5h; Inert atmosphere;	1.32 g
With triethylamine In acetone at 20℃; for 0.5h; Inert atmosphere;	1.32 g

: 79-10-7
acrylic acid

: 135-19-3
β-naphthol

A: 52684-34-1
2-naphthyl acrylate

B: 111709-01-4
β-Naphthyl-β-chlorpropionat

Conditions

Conditions	Yield
With phosphorus pentachloride In neat (no solvent) 1.) 110-120 deg C, 1 h, 2.) room temp., 2.5 h then 90 deg C, 3 h;	A n/a B 43%

...Expand

: 814-68-6
acryloyl chloride

: 135-19-3
β-naphthol

A: 52684-34-1
2-naphthyl acrylate

B: 111709-01-4
β-Naphthyl-β-chlorpropionat

Conditions

Conditions	Yield
With aluminium trichloride In neat (no solvent) 1.) 80-90 deg C, 3 h, 2.) 100 deg C, 1 h;	A n/a B 43%

...Expand

: 1056904-02-9
N-(4-chlorobenzylidene)-4-methoxybenzenesulfonamide

: 52684-34-1
2-naphthyl acrylate

: 1268833-26-6
(R)-naphthalen-2-yl 2-((4-chlorophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With tert-butyl (2-((4-((1R)-7-ethylhexahydro-1H-3,7-methanopyrrolo[2,1-c][1,4]oxazin-1-yl)quinolin-6-yl)amino)-2-oxoethyl)carbamate; β-naphthol In dichloromethane at -30℃; for 48h; Morita-Baylis-Hillman Alkylation; Inert atmosphere; enantioselective reaction;	100%

: 52684-34-1
2-naphthyl acrylate

: 1241834-17-2
C16H29NO4S2Si

: 1241833-84-0
C23H33NO4SSi

Conditions

Conditions	Yield
With C26H27N3O2; β-naphthol In dichloromethane at 10℃; for 12h; Aza-Morita-Baylis-Hillman reaction; Molecular sieve; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

: 52684-34-1
2-naphthyl acrylate

: 1241834-07-0
C18H23NO5S2

A: 1056904-26-7
C25H27NO5S

B: 1241833-79-3
C19H16O4S

Conditions

Conditions	Yield
With C26H27N3O2; β-naphthol In dichloromethane at 10℃; for 12h; Aza-Morita-Baylis-Hillman reaction; Molecular sieve; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	A 99% B n/a

...Expand

: 52684-34-1
2-naphthyl acrylate

: 73845-05-3
(E)-N-benzylidenemethanesulfonamide

: 1268833-10-8
C21H19NO4S

Conditions

Conditions	Yield
With (S)-N-(1-(diphenylphosphanyl)-3-methylbutan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at 20℃; for 24h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

: 1217-89-6
1-benzylisatin

: 52684-34-1
2-naphthyl acrylate

: 1263090-11-4
C28H21NO4

Conditions

Conditions	Yield
With 4-(3-ethyl-4-oxa-1-azatricyclo[4,4,0,0(3,8)]dec-5-yl)quinolin-6-ol In dichloromethane at 20℃; for 40h; asymmetric Morita-Baylis-Hillman reaction; optical yield given as %ee; enantioselective reaction;	97%

: 52684-34-1
2-naphthyl acrylate

: N-[1-(4-Fluoro-phenyl)-meth-(E)-ylidene]-4-methoxy-benzenesulfonamide

: 1268833-24-4
(R)-naphthalen-2-yl 2-((4-fluorophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	96%

: 1056904-04-1
C15H15NO3S

: 52684-34-1
2-naphthyl acrylate

: 1056904-18-7
C28H25NO5S

Conditions

Conditions	Yield
With 6'-N-boc-glycine-β-ICD; β-naphthol In dichloromethane at -30℃; for 68h; Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: 52960-60-8
N-benzylidene-4-methoxy-benzenesulfonamide

: 1056904-12-1
naphthalen-2-yl (S)-2-((4-Methoxyphenylsulfonamido)(phenylmethyl))acrylate

Conditions

Conditions	Yield
With 6'-N-boc-glycine-β-ICD; β-naphthol In dichloromethane at -30℃; Reactivity; Reagent/catalyst; Solvent; Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: 1241834-11-6
C21H27NO5S2

: 1056904-27-8
C28H31NO5S

Conditions

Conditions	Yield
With C26H27N3O2; β-naphthol In dichloromethane at 10℃; for 12h; Aza-Morita-Baylis-Hillman reaction; Molecular sieve; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: C15H12F3NO3S

: 1268833-30-2
(R)-naphthalen-2-yl 2-((4-methoxyphenylsulfonamido)(2-(trifluoromethyl)phenyl)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: C14H12ClNO3S

: 1268833-31-3
(S)-naphthalen-2-yl 2-((2-chlorophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: C14H12FNO3S

: 1268833-33-5
(S)-naphthalen-2-yl 2-((2-fluorophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: C12H11NO3S2

: 1268833-35-7
(S)-naphthalen-2-yl 2-((4-methoxyphenylsulfonamido)(thiophen-2-yl)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: 52684-34-1
2-naphthyl acrylate

: C14H12BrNO3S

: 1268833-25-5
(R)-naphthalen-2-yl 2-((4-bromophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	95%

: (E)-N-(furan-2-ylmethylene)-4-methoxybenzenesulfonamide

: 52684-34-1
2-naphthyl acrylate

: 1268833-34-6
(S)-naphthalen-2-yl 2-(furan-2-yl(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	93%

: 52684-34-1
2-naphthyl acrylate

: 1191127-92-0
C15H12F3NO3S

: 1268833-27-7
(R)-naphthalen-2-yl 2-((4-methoxyphenylsulfonamido)(4-(trifluoromethyl)phenyl)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	93%

: 52684-34-1
2-naphthyl acrylate

: 1191127-96-4
C14H12BrNO3S

: 1268833-32-4
(S)-naphthalen-2-yl 2-((2-bromophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	93%

: 861145-19-9
(E)-4-methoxy-N-((E)-p-tolylethylidene)benzenesulfonamide

: 52684-34-1
2-naphthyl acrylate

: 1268833-22-2
(R)-naphthalen-2-yl 2-((4-methoxyphenylsulfonamido)(p-tolyl)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	91%

: 1056904-01-8
4-methoxy-N-(4-methylbenzylidene)benzenesulfonamide

: 52684-34-1
2-naphthyl acrylate

: 1056904-13-2
C28H25NO5S

Conditions

Conditions	Yield
With 6'-N-boc-glycine-β-ICD; β-naphthol In dichloromethane at -30℃; for 67h; Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	90%

: 52684-34-1
2-naphthyl acrylate

: C16H17NO3S

: 1268833-23-3
(R)-naphthalen-2-yl 2-((4-ethylphenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	90%

: 52684-34-1
2-naphthyl acrylate

: (E)-N-benzylidene-4-methoxybenzene sulfonamide

: 1268833-09-5
(R)-naphthalen-2-yl 2-((4-methoxyphenylsulfonamido)(phenyl)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	89%

: 52684-34-1
2-naphthyl acrylate

: 63160-16-7
4-nitro-N-[(1E)-phenylmethylidene]benzene-1-sulfonamide

: 1268849-55-3
C26H20N2O6S

Conditions

Conditions	Yield
With (S)-N-(1-(diphenylphosphanyl)-3-methylbutan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at 20℃; for 24h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	88%

: 52684-34-1
2-naphthyl acrylate

: C14H12ClNO3S

: 1268833-29-9
(R)-naphthalen-2-yl 2-((3-chlorophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	85%

: 4290-94-2
N-ethylisatin

: 52684-34-1
2-naphthyl acrylate

: 1392206-63-1
naphthalen-2-yl 2-(1-ethyl-3-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)acrylate

Conditions

Conditions	Yield
With BF4(1-)*C9H19N2O(1+); 1,8-diazabicyclo[5.4.0]undec-7-ene at 20℃; for 0.416667h; Baylis-Hillman reaction;	85%

: 52684-34-1
2-naphthyl acrylate

: N,N-di(buta-2,3-dien-1-yl)-4-methylbenzenesulfonamide

: C28H27NO4S

Conditions

Conditions	Yield
With (R)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(bis(3,5-di-t-butyl-4-methoxyphenyl))phosphine; bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; hydrogen In tetrahydrofuran; dichloromethane at 40℃; for 16h; regioselective reaction;	85%

: 1056904-03-0
C14H12BrNO3S

: 52684-34-1
2-naphthyl acrylate

: 1056904-17-6
naphthalen-2-yl (S)-2-((3-bromophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With 6'-N-boc-glycine-β-ICD; β-naphthol In dichloromethane at -30℃; for 72h; Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	84%

: 52684-34-1
2-naphthyl acrylate

: 73845-03-1
4-Methoxy-N-[1-(4-methoxy-phenyl)-meth-(E)-ylidene]-benzenesulfonamide

: 1056904-16-5
naphthalen-2-yl (S)-2-((4-methoxyphenyl)(4-methoxyphenylsulfonamido)methyl)-acrylate

Conditions

Conditions	Yield
With 6'-N-boc-glycine-β-ICD; β-naphthol In dichloromethane at -30℃; for 80h; Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	84%

: 52684-34-1
2-naphthyl acrylate

: 1191127-93-1
C14H12ClNO3S

: 1268833-26-6
(R)-naphthalen-2-yl 2-((4-chlorophenyl)(4-methoxyphenylsulfonamido)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	84%

: 52684-34-1
2-naphthyl acrylate

: 1312951-18-0
C14H12N2O5S

: 1268849-56-4
(R)-naphthalen-2-yl 2-((4-methoxyphenylsulfonamido)(4-nitrophenyl)methyl)acrylate

Conditions

Conditions	Yield
With N-((2S,3R)-3-((2,3-dimethylbutan-2-yl)dimethylsilyloxy)-1-(diphenylphosphino)butan-2-yl)-4-methylbenzenesulfonamide In tetrahydrofuran at -30℃; for 48h; Aza-Morita-Baylis-Hillman reaction; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	84%

2-Naphthyl acrylate Specification

The 2-Propenoic acid, 2-naphthalenyl ester, with the CAS registry number 52684-34-1, is also known as 2-Naphthyl acrylate. It belongs to the product categories of Monomer; C12 to C63 Photonic and Optical Materials; Carbonyl Compounds; Esters; Photoluminescent Materials > Fluorescent Monomers. This chemical's molecular formula is C₁₃H₁₀O₂ and molecular weight is 198.22. What's more, its IUPAC name is called 2-Naphthyl acrylate.

Physical properties about 2-Propenoic acid, 2-naphthalenyl ester are: (1)ACD/LogP: 3.171; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.17; (4)ACD/LogD (pH 7.4): 3.17; (5)ACD/BCF (pH 5.5): 151.26; (6)ACD/BCF (pH 7.4): 151.26; (7)ACD/KOC (pH 5.5): 1264.33; (8)ACD/KOC (pH 7.4): 1264.33; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 26.3 Å²; (13)Index of Refraction: 1.609; (14)Molar Refractivity: 59.795 cm³; (15)Molar Volume: 172.778 cm³; (16)Polarizability: 23.704×10^-24cm³; (17)Surface Tension: 42.602 dyne/cm; (18)Density: 1.147 g/cm³; (19)Flash Point: 143.685 °C; (20)Enthalpy of Vaporization: 58.949 kJ/mol; (21)Boiling Point: 345.426 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25 °C.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin, eyes and respiratory system or other mucous membranes. In case of contacting with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(Oc2ccc1c(cccc1)c2)\C=C
(2) InChI: InChI=1S/C13H10O2/c1-2-13(14)15-12-8-7-10-5-3-4-6-11(10)9-12/h2-9H,1H2
(3) InChIKey: SLVJUZOHXPZVLR-UHFFFAOYSA-N

Product Name

2-Naphthyl acrylate

Synthetic route

2-Naphthyl acrylate Specification

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