Product Name

  • Name

    3-Hydroxytyramine hydrochloride

  • EINECS 200-527-8
  • CAS No. 62-31-7
  • Article Data12
  • CAS DataBase
  • Density 1.4 g/cm3
  • Solubility Soluble in water
  • Melting Point 248-250 °C(lit.)
  • Formula C8H12ClNO2
  • Boiling Point 337.7 °C at 760 mmHg
  • Molecular Weight 189.642
  • Flash Point 158 °C
  • Transport Information
  • Appearance off-white crystals
  • Safety 26-36
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 62-31-7 (3-Hydroxytyramine hydrochloride)
  • Hazard Symbols IrritantXi
  • Synonyms 1,2-Benzenediol,4-(2-aminoethyl)-, hydrochloride (9CI);Pyrocatechol, 4-(2-aminoethyl)-,hydrochloride (8CI);2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride;3,4-Dihydroxy-b-phenethylaminehydrochloride;3,4-Dihydroxyphenethylamine hydrochloride;4-(2-Aminoethyl)-1,2-benzenediol hydrochloride;ASL 279;Cardiosteril;Dopamine chloride;Dopamine hydrochloride;Dopastat;Revivan;Tensamin;m-Hydroxytyramine hydrochloride;b-(3,4-Dihydroxyphenyl)ethylaminehydrochloride;
  • PSA 66.48000
  • LogP 2.10130

Synthetic route

N-(tert-butoxycarbonyl)dopamine
37034-31-4

N-(tert-butoxycarbonyl)dopamine

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
With methanol; chloro-trimethyl-silane for 3h; Reflux;100%
3,4-bis(benzyloxy)-β-nitrostyrene
1699-54-3

3,4-bis(benzyloxy)-β-nitrostyrene

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; hydrogen; palladium on activated charcoal In ethanol under 760 Torr; for 24h; Ambient temperature;99%
2-(3,4-dimethoxyphenyl)-ethylamine
120-20-7

2-(3,4-dimethoxyphenyl)-ethylamine

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; acetic acid In water at 160℃; for 6h; Inert atmosphere;98.6%
With hydrogenchloride; water at 100℃; for 144h;76%
With hydrogenchloride; sodium hypophosphite; ion-exchanger Dowex 50 X2-200; hydrogen bromide; isobutyric Acid for 2h; Heating;
Multi-step reaction with 3 steps
1: hydrogen bromide / ethanol / 0.5 h / 50 °C
2: hydrogen bromide / 5 h / 110 - 115 °C / Inert atmosphere
3: hydrogenchloride / isopropyl alcohol / 1 h / 80 °C / Inert atmosphere; Reflux
View Scheme
3-hydroxytyramine hydrobromide
645-31-8

3-hydroxytyramine hydrobromide

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol at 70 - 80℃; Inert atmosphere;93%
With hydrogenchloride In isopropyl alcohol at 80℃; for 1h; Solvent; Inert atmosphere; Reflux;90.6%
3-Methoxytyramine hydrochloride
1477-68-5

3-Methoxytyramine hydrochloride

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
Stage #1: 3-Methoxytyramine hydrochloride With hydrogen bromide for 6h; Reflux;
Stage #2: With hydrogenchloride In water		69.81%
C8H11NO2*C7H8N2O*2ClH

C8H11NO2*C7H8N2O*2ClH

A

dopamine hydrochloride
62-31-7

dopamine hydrochloride

B

N-methylnicotinamide hydrochloride
29711-57-7

N-methylnicotinamide hydrochloride

Conditions
ConditionsYield
at 28℃; Equilibrium constant; Thermodynamic data; association enthalpy: ΔH0 (kcal mol-1) = -3.2 (pH=1);
N-(N-acetyl-L-methionyl)-O,O-bis(ethoxycarbonyl)dopamine

N-(N-acetyl-L-methionyl)-O,O-bis(ethoxycarbonyl)dopamine

A

3,4-dihydroxyphenylacetate
102-32-9

3,4-dihydroxyphenylacetate

B

dopamine hydrochloride
62-31-7

dopamine hydrochloride

C

dopamine-30-sulfate

dopamine-30-sulfate

Conditions
ConditionsYield
at 37℃; pharmacokinetic; concentrations of products in plasma after oral administration of title compound to dogs;
...Expand
C44H36N4O12P2(2-)*C8H11NO2*H(1+)

C44H36N4O12P2(2-)*C8H11NO2*H(1+)

A

dopamine hydrochloride
62-31-7

dopamine hydrochloride

B

C44H36N4O12P2(2-)

C44H36N4O12P2(2-)

Conditions
ConditionsYield
In d(4)-methanol; water-d2 Equilibrium constant;
3,4-dimethoxyphenylacetonitrile
93-17-4

3,4-dimethoxyphenylacetonitrile

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: diborane / tetrahydrofuran / 16 h / 55 °C / Inert atmosphere
1.2: 0 - 20 °C
2.1: hydrogenchloride; water / 144 h / 100 °C
View Scheme
C23H35NO8

C23H35NO8

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
Stage #1: C23H35NO8 With trifluoroacetic acid In dichloromethane
Stage #2: With hydrogenchloride In methanol; diethyl ether regioselective reaction;
1,2-dimethoxy-4-(2-nitro-vinyl)-benzene
4230-93-7

1,2-dimethoxy-4-(2-nitro-vinyl)-benzene

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: ammonium formate; 5%-palladium/activated carbon / methanol / 60 - 65 °C / Inert atmosphere
2: hydrogen bromide / water / 110 - 120 °C / Inert atmosphere
3: hydrogenchloride / water; isopropyl alcohol / 70 - 80 °C / Inert atmosphere
View Scheme
3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

dopamine hydrochloride
62-31-7

dopamine hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: methylamine hydrochloride; triethylamine / ethanol / 20 °C
2: ammonium formate; 5%-palladium/activated carbon / methanol / 60 - 65 °C / Inert atmosphere
3: hydrogen bromide / water / 110 - 120 °C / Inert atmosphere
4: hydrogenchloride / water; isopropyl alcohol / 70 - 80 °C / Inert atmosphere
View Scheme
dopamine hydrochloride
62-31-7

dopamine hydrochloride

3-(3,4-dihydroxyphenyl)propanoic acid pentafluorophenyl ester
169232-24-0

3-(3,4-dihydroxyphenyl)propanoic acid pentafluorophenyl ester

N-(3,4-dihydroxyhydrocinnamoyl)dopamine

N-(3,4-dihydroxyhydrocinnamoyl)dopamine

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 2h;100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

dopamine hydrochloride
62-31-7

dopamine hydrochloride

N-(tert-butoxycarbonyl)dopamine
37034-31-4

N-(tert-butoxycarbonyl)dopamine

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 2h;100%
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 2h;100%
With triethylamine In methanol99%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

acryloyl chloride
814-68-6

acryloyl chloride

N-[2-(3,4-Dihydroxy-phenyl)-ethyl]acrylamide
201610-44-8

N-[2-(3,4-Dihydroxy-phenyl)-ethyl]acrylamide

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran; methanol at 0 - 20℃; for 2h;100%
With triethylamine In tetrahydrofuran; methanol at 20℃; pH=9; Cooling with ice;65%
With triethylamine In tetrahydrofuran; methanol for 1h; Cooling with ice;57%
With borax; sodium hydrogencarbonate; sodium hydroxide In tetrahydrofuran; water at 20℃; for 14h; pH=8; Inert atmosphere;54%
With triethylamine In tetrahydrofuran; methanol at 20℃; for 1h;
dopamine hydrochloride
62-31-7

dopamine hydrochloride

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

ethyl (3,4-dihydroxyphenethyl)carbamate
36205-85-3

ethyl (3,4-dihydroxyphenethyl)carbamate

Conditions
ConditionsYield
Stage #1: dopamine hydrochloride With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 1h;
Stage #2: chloroformic acid ethyl ester In tetrahydrofuran; water at 20℃; for 5h;		100%
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

dopamine hydrochloride
62-31-7

dopamine hydrochloride

C23H35NO8

C23H35NO8

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 16h; Inert atmosphere;100%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

2,5-anhydro-D-mannose
495-75-0

2,5-anhydro-D-mannose

1-(α-D-arabinofuranosyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
87943-09-7, 87984-47-2

1-(α-D-arabinofuranosyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride

Conditions
ConditionsYield
In water for 48h; Ambient temperature;98%
for 48h; Ambient temperature;98%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

3,4-dichlorobenzaldehyde
6287-38-3

3,4-dichlorobenzaldehyde

1-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol; hydrochloride

1-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol; hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol for 12h; Heating;98%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

stearic acid
57-11-4

stearic acid

N-stearoyldopamine
105955-10-0

N-stearoyldopamine

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In tetrahydrofuran Ambient temperature;98%
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In dichloromethane; ethyl acetate at 0 - 20℃; for 0.5h; Inert atmosphere;35%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-(3,4-bis((tert-butyldimethylsilyl)oxy)phenyl)ethan-1-amine
165749-18-8

2-(3,4-bis((tert-butyldimethylsilyl)oxy)phenyl)ethan-1-amine

Conditions
ConditionsYield
With 1H-imidazole In dichloromethane at 20℃; for 16h; Inert atmosphere;98%
With 1H-imidazole In dichloromethane at 20℃; for 2h;95.8%
With 1H-imidazole In dichloromethane at 20℃; Inert atmosphere;86%
trifluoroacetic acid-methyl ester
431-47-0

trifluoroacetic acid-methyl ester

dopamine hydrochloride
62-31-7

dopamine hydrochloride

N-<2-(3,4-Dihydroxyphenyl)ethyl>trifluoracetamid
65846-04-0

N-<2-(3,4-Dihydroxyphenyl)ethyl>trifluoracetamid

Conditions
ConditionsYield
With triethylamine In methanol at 20℃; Inert atmosphere;98%
With triethylamine In methanol at 20℃;98%
With triethylamine In methanol at 30℃; for 16h;92%
With triethylamine In methanol at 20℃; for 12h;86%
With triethylamine In methanol at 20℃; Sealed tube;82.2%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

4-methyl-1H-imidazole-5-carbaldehyde
68282-53-1

4-methyl-1H-imidazole-5-carbaldehyde

4-(2-(((4-methyl-1H-imidazol-5-yl)methylene)amino)ethyl)benzene-1,2-diol
1363301-25-0

4-(2-(((4-methyl-1H-imidazol-5-yl)methylene)amino)ethyl)benzene-1,2-diol

Conditions
ConditionsYield
Stage #1: dopamine hydrochloride With triethylamine In ethanol for 0.5h;
Stage #2: 4-methyl-1H-imidazole-5-carbaldehyde In ethanol for 4h; Reflux;		98%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

3-methoxy-benzaldehyde
591-31-1

3-methoxy-benzaldehyde

1-(3-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol; hydrochloride

1-(3-Methoxy-phenyl)-1,2,3,4-tetrahydro-isoquinoline-6,7-diol; hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In methanol for 12h; Heating;97%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

6,7-dihydroxy-1-(2-methoxyphenyl)-1,2,3,4-tetrahydroisoquinolinium chloride

6,7-dihydroxy-1-(2-methoxyphenyl)-1,2,3,4-tetrahydroisoquinolinium chloride

Conditions
ConditionsYield
With hydrogenchloride In methanol for 12h; Heating;97%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

3-(3,5-Dihydroxy-phenyl)-propionic acid pentafluorophenyl ester
188662-00-2

3-(3,5-Dihydroxy-phenyl)-propionic acid pentafluorophenyl ester

3-(3,5-Dihydroxy-phenyl)-N-[2-(3,4-dihydroxy-phenyl)-ethyl]-propionamide

3-(3,5-Dihydroxy-phenyl)-N-[2-(3,4-dihydroxy-phenyl)-ethyl]-propionamide

Conditions
ConditionsYield
With triethylamine In chloroform; N,N-dimethyl-formamide for 2h; Ambient temperature;97%
cis-Octadecenoic acid
112-80-1

cis-Octadecenoic acid

dopamine hydrochloride
62-31-7

dopamine hydrochloride

N-oleoyldopamine
105955-11-1

N-oleoyldopamine

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In tetrahydrofuran Ambient temperature;97%
Stage #1: cis-Octadecenoic acid With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; for 0.5h;
Stage #2: dopamine hydrochloride In dichloromethane for 12h;		58%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

C26H53NO2Si3

C26H53NO2Si3

Conditions
ConditionsYield
With triethylamine In acetonitrile at 0 - 20℃; Inert atmosphere;97%
1-[(2-oxazepan-1-yl)carbonyl]azepan-2-one
19494-73-6

1-[(2-oxazepan-1-yl)carbonyl]azepan-2-one

dopamine hydrochloride
62-31-7

dopamine hydrochloride

N-(3,4-dihydroxyphenethyl)-2-oxoazepane-1-carboxamide

N-(3,4-dihydroxyphenethyl)-2-oxoazepane-1-carboxamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 80℃; for 24h; Inert atmosphere;97%
cyclo-[2,6-{CH3N(CH2CH2)2NCH2}2C6H3]2Sb2O2

cyclo-[2,6-{CH3N(CH2CH2)2NCH2}2C6H3]2Sb2O2

dopamine hydrochloride
62-31-7

dopamine hydrochloride

[2,6-{CH3N(CH2CH2)2NCH2}2C6H3Sb(1,2-O2-C6H3-4-(CH2)2NH3)]Cl

[2,6-{CH3N(CH2CH2)2NCH2}2C6H3Sb(1,2-O2-C6H3-4-(CH2)2NH3)]Cl

Conditions
ConditionsYield
In ethanol at 20℃; for 24h;96%
ethylenediaminetetraacetic dianhydride
23911-25-3

ethylenediaminetetraacetic dianhydride

dopamine hydrochloride
62-31-7

dopamine hydrochloride

C26H34N4O10
1357356-94-5

C26H34N4O10

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 70℃; for 18h; Inert atmosphere;95%
linoleic acid
60-33-3

linoleic acid

dopamine hydrochloride
62-31-7

dopamine hydrochloride

(Z,Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]-octadeca-9,12-dienamide
105955-12-2

(Z,Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]-octadeca-9,12-dienamide

Conditions
ConditionsYield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In tetrahydrofuran Ambient temperature;94%
terephthalic acid
100-21-0

terephthalic acid

dopamine hydrochloride
62-31-7

dopamine hydrochloride

N1,N4-bis(3,4-dihydroxyphenethyl)terephthalamide

N1,N4-bis(3,4-dihydroxyphenethyl)terephthalamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h; Inert atmosphere;94%
dopamine hydrochloride
62-31-7

dopamine hydrochloride

C8H7NO2

C8H7NO2

Conditions
ConditionsYield
With sodium hydrogencarbonate; potassium hexacyanoferrate(III) In water at 20 - 68℃; for 2h; Inert atmosphere;93.6%
D-Glyceraldehyde
453-17-8

D-Glyceraldehyde

dopamine hydrochloride
62-31-7

dopamine hydrochloride

(1'S)-1-(1',2'-dihydroxyethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
259183-94-3

(1'S)-1-(1',2'-dihydroxyethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline

Conditions
ConditionsYield
In methanol Heating;93%
In methanol 1) RT, overnight, 2) reflux, 2 d;93%
C32H47NO7

C32H47NO7

dopamine hydrochloride
62-31-7

dopamine hydrochloride

C56H74N4O10

C56H74N4O10

Conditions
ConditionsYield
Stage #1: C32H47NO7 With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 0℃; for 0.05h;
Stage #2: dopamine hydrochloride In N,N-dimethyl-formamide at 20℃; for 72h;		93%
D-Glucose
2280-44-6

D-Glucose

dopamine hydrochloride
62-31-7

dopamine hydrochloride

6,7-dihydroxy-1-(D-gluco-pentitol-1'-yl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
87943-10-0, 87984-48-3

6,7-dihydroxy-1-(D-gluco-pentitol-1'-yl)-1,2,3,4-tetrahydroisoquinoline hydrochloride

Conditions
ConditionsYield
In water for 48h; Heating;92%
D-glucose
50-99-7

D-glucose

dopamine hydrochloride
62-31-7

dopamine hydrochloride

6,7-dihydroxy-1-(D-gluco-pentitol-1'-yl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
87943-10-0, 87984-48-3

6,7-dihydroxy-1-(D-gluco-pentitol-1'-yl)-1,2,3,4-tetrahydroisoquinoline hydrochloride

Conditions
ConditionsYield
In water for 48h; Heating;92%

3-Hydroxytyramine hydrochloride Chemical Properties

Molecular Structure of 3-Hydroxytyramine hydrochloride (CAS NO.62-31-7):

IUPAC Name: 4-(2-aminoethyl)benzene-1,2-diol hydrochloride 
Empirical Formula: C8H12ClNO2
Molecular Weight: 189.6394
H bond acceptors: 3
H bond donors: 4
Freely Rotating Bonds: 5
Polar Surface Area: 21.7Å2
Flash Point: 158 °C
Enthalpy of Vaporization: 60.4 kJ/mol
Boiling Point: 337.7 °C at 760 mmHg
Vapour Pressure: 5.27E-05 mmHg at 25°C
Melting point: 248-250 °C(lit.)
Solubility alcohol: 20 mg/mL
Water Solubility: soluble
Sensitive: Air & Light Sensitive
Merck: 14,3421
BRN: 3656720
EINECS: 200-527-8
Product Categories: Anilines, Aromatic Amines and Nitro Compounds; Dopamine receptor
Stability: Stable. Incompatible with strong oxidizing agents. Combustible.
InChI
InChI=1/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
Smiles
c1(cc(c(O)cc1)O)CCN.Cl

3-Hydroxytyramine hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 79mg/kg (79mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: ATAXIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 2208, 1978.
man TDLo intravenous 1429ug/kg (1.429mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE Critical Care Medicine. Vol. 9, Pg. 658, 1981.
mouse LD50 intraperitoneal 914mg/kg (914mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
mouse LD50 intravenous 156mg/kg (156mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
mouse LD50 oral 4361mg/kg (4361mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
mouse LD50 subcutaneous 1366mg/kg (1366mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
rabbit LD50 intravenous 90mg/kg (90mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
rat LD50 intraperitoneal 597mg/kg (597mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
rat LD50 intravenous 4800ug/kg (4.8mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
rat LD50 oral 2859mg/kg (2859mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.
rat LD50 subcutaneous 647mg/kg (647mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 2311, 1974.

3-Hydroxytyramine hydrochloride Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany: 2
RTECS: UX1092000
F: 8-10-23
Hazard Note: Irritant
HS Code: 29222900

3-Hydroxytyramine hydrochloride Specification

  3-Hydroxytyramine hydrochloride , with CAS number of 62-31-7, can be called .beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride ; 1,2-Benzenediol, 4- (2-aminoethyl)-, hydrochloride ; 1,2-benzenediol, 4-(2-aminoethyl)-, hydrochloride (1:1) ; 4-(2-aminoéthyl)benzène-1,2-diol chlorhydrate ; 4-(2-aminoethyl)-Pyrocatechol hydrochloride . It is an off-white crystal.

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