Conditions | Yield |
---|---|
With silica-supported Jones reagent In dichloromethane for 0.00269444h; | 100% |
With Oxone; potassium bromide In water; acetonitrile at 20℃; for 3h; Reagent/catalyst; Solvent; | 99% |
With iodine pentoxide; potassium bromide In water at 20℃; for 12h; | 98% |
2-methyl-2-(4-nitrophenyl)-1,3-dithiane
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With water; silver (I) ion In 1,4-dioxane at 25℃; Kinetics; Product distribution; var. temp.; | 100% |
With dihydrogen peroxide; niobium pentachloride; sodium iodide In water; ethyl acetate at 20℃; for 5h; | 100% |
With iron(III)-acetylacetonate; dihydrogen peroxide; sodium iodide In water; ethyl acetate at 20℃; for 18.4h; | 92% |
Conditions | Yield |
---|---|
With bis(η3-allyl-μ-chloropalladium(II)) In N,N,N,N,N,N-hexamethylphosphoric triamide at 20℃; for 0.166667h; Mechanism; | 100% |
With bis(η3-allyl-μ-chloropalladium(II)) In N,N,N,N,N,N-hexamethylphosphoric triamide at 20℃; for 0.166667h; | 100% |
With benzoylchlorobis(triphenylphosphine)palladium(II) In chloroform at 65℃; for 24h; | 95% |
With N,N,N,N,N,N-hexamethylphosphoric triamide; poly-γ-(diphenylphosphino)propylsiloxane palladium(0) at 65℃; for 20h; | 83% |
1,1-dimethoxy-1-(4-nitrophenyl)ethane
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With water at 80℃; for 2h; | 100% |
With carbon tetrabromide In water; acetonitrile at 80℃; for 2h; | 97% |
1-(4-nitrophenyl)-2-(phenylselanyl)ethan-1-one
A
diphenyl diselenide
B
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With GLUTATHIONE In methanol Product distribution; Mechanism; 0.1 M phosphate buffer, pH=6.9; differnt quantity of glutathione; relative reactivity to α-(phenylselenenyl)acetophenone; | A 99% B 87% |
Conditions | Yield |
---|---|
With water at 60℃; for 20h; Sealed tube; | 99% |
With C22H20AuN3O2P(1+)*CF3O3S(1-); water; silver trifluoromethanesulfonate; acetic acid at 100℃; for 10h; | 98% |
With chloro(1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene)gold(I) In methanol; water at 120℃; for 6h; Schlenk technique; regioselective reaction; | 94% |
Conditions | Yield |
---|---|
With nickel-doped graphene carbon nitride nanoparticles; air In ethanol at 25℃; for 8h; Irradiation; Green chemistry; | 98% |
With tert.-butylhydroperoxide; phosphomolybdic acid; copper(II) acetate monohydrate In water; acetonitrile at 90℃; for 10h; Sealed tube; | 97% |
With Oxone; water; potassium bromide In dichloromethane at 20℃; for 16h; Time; Irradiation; Sealed tube; | 96% |
p-nitroacetophenone oxime
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With water; oxygen In acetonitrile at 60℃; under 760.051 Torr; for 2h; Autoclave; Green chemistry; | 98% |
With Dess-Martin periodane In dichloromethane; water for 0.25h; | 96% |
With sodium tungstate; dihydrogen peroxide In water; acetone at -5 - 20℃; for 5h; | 96% |
2-methyl-2-(4-nitrophenyl)-1,3-oxathiolane
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With t-butyl thionitrite In acetonitrile at 0℃; for 0.6h; | 98% |
With N-Bromosuccinimide; water In acetone at 20℃; for 6h; Hydrolysis; | 88% |
With eosin Y disodium salt In acetonitrile at 20℃; for 3h; Irradiation; | 68% |
With oxygen; Rose Bengal lactone In ethanol pH=7.4; Kinetics; | 50% |
1-(4-nitro-phenyl)-ethanone-diethylacetal
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With water at 80℃; for 2h; | 98% |
With carbon tetrabromide In water; acetonitrile at 80℃; for 2h; Product distribution; other reaction conditions; |
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With silica-OSO3H; silica gel In toluene at 60 - 70℃; for 1h; | 98% |
With tetrachlorosilane; silica gel In toluene at 60 - 70℃; for 1.33333h; | 93% |
With potassium sulfate; potassium hydrogensulfate; potassium peroxomonosulfate; aluminium trichloride In acetonitrile Heating; |
4-methyl-N'-(1-(4-nitrophenyl)ethylidene)benzenesulfonohydrazide
A
(4-nitrophenyl)ethanone
B
4-nitro-benzoic acid
Conditions | Yield |
---|---|
With silica-supported selenamide; dihydrogen peroxide In tert-butyl alcohol at 55℃; for 20h; | A 98% B 2% |
α,α-dibromo-4-nitroethylbenzene
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With water In dichloromethane at 20℃; for 24h; visible light irradiation; | 98% |
2-methyl-2-(4-nitrophenyl)-1,3-dithiane
B
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With Methylthio(bismethylthio)sulfonium hexachloroantimonate In dichloromethane at -77℃; for 0.0166667h; Yields of byproduct given; | A n/a B 97% |
Conditions | Yield |
---|---|
With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-d6-formamide at 20℃; for 4h; Irradiation; | 97% |
With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate In 2,2,2-trifluoroethanol at 20℃; for 4h; UV-irradiation; Sealed tube; Green chemistry; | 96% |
With bismuth; ammonium fluoride-hydrogen fluoride In water at 20℃; for 3h; | 94% |
2-(4-nitrophenyl)-2-methyl-1,3-dioxolane
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With Montmorillonite K 10; water In acetone for 5.5h; Heating; | 97% |
With carbon tetrabromide In water; acetonitrile at 80℃; for 6h; | 96% |
With erbium(III) triflate In nitromethane at 20℃; for 96h; | 94% |
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With tert.-butylhydroperoxide; vanadia In water at 100℃; for 7h; | 97% |
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With 1-amino-3-methylbutane; ammonium chlorate; potassium bromide at 50 - 57℃; for 1h; Temperature; | 97% |
α-(2,4-dinitrophenyl)ethyl nitrate
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With sodium ethanolate; acetic acid In ethanol at 22 - 25℃; for 0.333333h; pH=7; | 96% |
With sodium methylate; potassium carbonate oder mit anderen Basen; | |
With sodium methylate; potassium carbonate oder mit anderen Basen; |
1-(4-nitrophenyl)ethanone hydrazone
A
(4-nitrophenyl)ethanone
B
1-(4-nitrophenyl)-1-diazoethane
Conditions | Yield |
---|---|
1-methylimidazole ligand In acetonitrile for 0.0833333h; | A 4% B 96% |
Conditions | Yield |
---|---|
With water; fluorine In chloroform; acetonitrile at -15℃; for 0.0333333h; Product distribution; other substituted anilines; | 95% |
With water; fluorine In chloroform; acetonitrile at -15℃; for 0.0333333h; | 95% |
With 1,9-diperoxynonanedioic acid In acetonitrile at 50℃; for 0.5h; | 94% |
p-nitrobenzene iodide
carbon monoxide
tetramethylstannane
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
bis(η3-allyl-μ-chloropalladium(II)) In N,N,N,N,N,N-hexamethylphosphoric triamide at 20℃; for 30h; | 95% |
With MCM-41-supported bidentate phosphine palladium(0) complex In N,N-dimethyl-formamide at 70℃; under 760.051 Torr; for 10h; Stille carbonylative cross-coupling; | 84% |
4-ethylnitrobenzene
A
1-[4-nitrophenyl]-1-ethanol
B
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With cerium(III) sulfate; barium bromate In water; acetonitrile for 24h; Heating; Title compound not separated from byproducts; | A n/a B 95% |
With N-hydroxyphthalimide; oxygen; acetaldehyde In acetonitrile Ambient temperature; | A 2 % Chromat. B 22 % Chromat. |
With oxygen under 760.051 Torr; Heating; | A 16.5 %Chromat. B 83.5 %Chromat. |
1-(4-nitro-phenyl)-ethylamine
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With 4-phenylnaphthalene-1,2-dione In acetonitrile at 80℃; for 36h; | 95% |
Multi-step reaction with 3 steps 1: N-chloro-succinimide / 0.17 h / 20 °C / Milling 2: triethylamine / 0.17 h / 20 °C / Milling 3: water; hydrogenchloride / tetrahydrofuran / 2 h / 20 °C View Scheme |
1-(4-nitrophenyl)-1-diazoethane
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With N,N'-bis(salicylidene)ethylenediaminatocobalt(III) hydroxide; oxygen In acetonitrile | 94% |
4-acetylphenylboronic acid
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With N-Bromosuccinimide; [bis(trifluoroacetoxy)iodo]benzene; sodium nitrite In acetonitrile at 20℃; for 3h; regioselective reaction; | 94% |
With bismuth (III) nitrate pentahydrate In toluene at 70 - 80℃; for 2h; Inert atmosphere; | 87% |
With 1,3-disulfonic acid imidazolium nitrate In neat (no solvent) at 20℃; for 0.0166667h; | 78% |
With dipotassium peroxodisulfate; bismuth (III) nitrate pentahydrate In benzene at 70℃; for 12h; Inert atmosphere; | 70% |
1,2-bis(1-(4-nitrophenyl)ethylidene)hydrazine
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With ammonium cerium(IV) nitrate In water; acetonitrile at 50℃; for 16h; Oxidation; | 93% |
With 2-phenyl-1,2-benzoisoselenazol-3(2H)-one; dihydrogen peroxide In methanol; water at 65℃; for 72h; | 90% |
With HOF* CH3CN In dichloromethane at 0℃; for 0.0166667h; | 90% |
With sulfuric acid; silica gel In hexane for 1h; | 86% |
4-nitro-(1-bromoethyl)benzene
A
(4-nitrophenyl)ethanone
B
4-nitro-benzoic acid
Conditions | Yield |
---|---|
With Oxone In water; acetonitrile at 20℃; for 5.5h; | A 93% B 5% |
p-nitrobenzene iodide
carbon monoxide
methylmercury(II) iodide
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
dichloro bis(acetonitrile) palladium(II) In N,N,N,N,N,N-hexamethylphosphoric triamide at 20℃; under 760 Torr; for 1.5h; Product distribution; various solvents, Pd-catalysts and reaction conditions; | 92% |
With tetra-(n-butyl)ammonium iodide; dichloro bis(acetonitrile) palladium(II) In N,N,N,N,N,N-hexamethylphosphoric triamide at 20℃; under 760 Torr; for 1.5h; | 85% |
(4-nitrophenyl)ethanone
p-nitroacetophenone oxime
Conditions | Yield |
---|---|
With hydroxylamine hydrochloride | 100% |
With hydroxylamine hydrochloride; sodium acetate In ethanol for 0.0166667h; Condensation; Irradiation; | 98% |
With hydroxylamine hydrochloride; silica gel for 0.1h; | 95% |
(4-nitrophenyl)ethanone
N-(4-acetylphenyl)hydroxylamine
Conditions | Yield |
---|---|
With 5% rhodium-on-charcoal; hydrazine hydrate In tetrahydrofuran at 0℃; for 3.5h; Inert atmosphere; | 100% |
With 5% rhodium-on-charcoal; hydrazine hydrate In tetrahydrofuran at 0℃; Inert atmosphere; | 100% |
With rhodium contaminated with carbon; hydrazine hydrate In tetrahydrofuran at 0℃; for 3.5h; Inert atmosphere; | 100% |
Conditions | Yield |
---|---|
With methyltriphenylphosphonium tetrahydroborate In dichloromethane Reduction; | 100% |
Stage #1: (4-nitrophenyl)ethanone With sodium tetrahydroborate at 25℃; for 0.5h; Ball milling; neat (no solvent); Stage #2: With water regiospecific reaction; | 100% |
With C40H37ClN2PRuS(1+)*C24H20B(1-); isopropyl alcohol; potassium hydroxide at 82℃; for 2h; Catalytic behavior; | 100% |
Conditions | Yield |
---|---|
With bromine In 1,4-dioxane; diethyl ether for 0.5h; Ambient temperature; | 100% |
With copper(ll) bromide In ethyl acetate at 60 - 65℃; for 8h; | 99% |
With copper(ll) bromide In ethyl acetate at 60 - 65℃; for 8h; | 99% |
Conditions | Yield |
---|---|
With hydrogen In methanol at 20℃; under 760.051 Torr; for 9h; | 100% |
With hydrogenchloride; ammonium chloride In tetrahydrofuran; water at 45℃; for 2h; Sealed tube; Green chemistry; | 100% |
With hydrogen In water at 50℃; under 750.075 Torr; for 1.5h; | 100% |
(4-nitrophenyl)ethanone
trimethyl orthoformate
1,1-dimethoxy-1-(4-nitrophenyl)ethane
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In methanol for 72h; | 100% |
With toluene-4-sulfonic acid In methanol at 20℃; | 95% |
With toluene-4-sulfonic acid In methanol at 20℃; for 48h; | 58% |
4-chlorobenzaldehyde
(4-nitrophenyl)ethanone
3-(4-chlorophenyl)-1-(4-nitrophenyl)-2-propen-1-one
Conditions | Yield |
---|---|
With potassium hydroxide In methanol; water at 20℃; for 0.5h; | 100% |
Stage #1: 4-chlorobenzaldehyde; (4-nitrophenyl)ethanone With calcium hydroxyapatite In methanol at 20℃; for 0.0833333h; Stage #2: With water for 1h; Claisen Schmidt condensation; Microwave irradiation; | 93% |
With sodium hydroxide In ethanol at 20℃; | 85% |
ethylene glycol
(4-nitrophenyl)ethanone
2-(4-nitrophenyl)-2-methyl-1,3-dioxolane
Conditions | Yield |
---|---|
With zeolite HSZ-360 In toluene for 1h; Heating; | 100% |
With cyclohexane at 105℃; for 1h; Dean-Stark; | 100% |
With ammonium bisulphate for 6h; Concentration; Reagent/catalyst; Dean-Stark; Reflux; Green chemistry; | 99% |
(4-nitrophenyl)ethanone
4-nitroacetophenone oxime
Conditions | Yield |
---|---|
With hydroxylamine hydrochloride; sodium acetate In methanol; water Reflux; | 100% |
With hydroxylamine hydrochloride; sodium acetate In methanol Reflux; | 100% |
With N-hydroxyphthalimide In water at 90℃; for 10h; Sealed tube; | 98% |
(4-nitrophenyl)ethanone
(1R)-1-(4-nitrophenyl)ethanol
Conditions | Yield |
---|---|
With (S,S)-RuCl2(2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl)(1,1-dianisyl-2-isopropyl-1,2-ethylenediamine); potassium tert-butylate; hydrogen In isopropyl alcohol at 26 - 30℃; under 6080 Torr; for 15h; | 100% |
With N(CH2)3CHCPh2OBO(n-Oct) | 100% |
With sodium tetrahydroborate; chloro-trimethyl-silane; polymer-supported chiral sulfonamide In tetrahydrofuran Heating; | 99% |
(4-nitrophenyl)ethanone
(S)-1-[4-nitrophenyl]ethanol
Conditions | Yield |
---|---|
With glucose dehydrogenase; D-glucose; ketoreductase from Pichia glucozyma; nicotinamide adenine dinucleotide phosphate In aq. buffer at 30℃; pH=8; Enzymatic reaction; enantioselective reaction; | 100% |
With D-glucose at 30℃; for 72h; pH=6.5; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee; enantioselective reaction; | 99% |
With D-glucose In aq. phosphate buffer at 25℃; for 24h; pH=7.0; stereoselective reaction; | 99% |
(4-nitrophenyl)ethanone
9-oxo-4,9-dihydro-pyrazolo[5,1-b]quinazoline-3-carbaldehyde
3-[(E)-3-(4-Nitro-phenyl)-3-oxo-propenyl]-4H-pyrazolo[5,1-b]quinazolin-9-one
Conditions | Yield |
---|---|
With piperidine In acetic acid; benzene for 24h; Heating; | 100% |
Conditions | Yield |
---|---|
With lithium tetrafluoroborate In acetonitrile at 20℃; for 7h; | 100% |
With potassium phtalimide at 20℃; for 1.5h; solvent-free; | 99% |
With rasta resin-PPh3BnCl In chloroform at 50℃; for 1.5h; Inert atmosphere; | 99% |
N-(2-bromobenzyl)-2-aminoethanol
(4-nitrophenyl)ethanone
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In benzene cyclocondensation; Heating; | 100% |
With p-toluenesulfonic acid monohydrate In benzene for 12h; Heating; | 100% |
Conditions | Yield |
---|---|
2,6-dimethylpyridine; zinc trifluoromethanesulfonate In dichloromethane at 20℃; for 24h; | 100% |
With C20H32N2O10 In water at 25℃; for 24h; | 97% |
With gadolinium(III) chloride In acetonitrile at 20℃; for 3h; | 85% |
(4-nitrophenyl)ethanone
(E)-N-[4-(1-{diaminomethylene}hydrazono)ethyl]-4-nitrobenzene hydrochloride
Conditions | Yield |
---|---|
With hydrogenchloride In methanol; water for 1h; Heating / reflux; | 100% |
formaldehyd
4-benzylpyperidine
(4-nitrophenyl)ethanone
C34H41N3O3
Conditions | Yield |
---|---|
With hydrogenchloride In ethanol Mannich reaction; Heating; | 100% |
4-nitrobenzaldehdye
ethyl 2-cyanoacetate
(4-nitrophenyl)ethanone
2-cyano-3-(4-nitrophenyl)-2-propenoic acid ethyl ester
Conditions | Yield |
---|---|
With SBA-15-supported poly(4-methylvinylpyridinium hydroxide) composite In water Knoevenagel condensation; Reflux; | 100% |
((1E,3E)-4-nitrobuta-1,3-dien-1-yl)benzene
(4-nitrophenyl)ethanone
(S,E)-3-(nitromethyl)-1-(4-nitrophenyl)-5-phenylpent-4-en-1-one
Conditions | Yield |
---|---|
With (S)-di-tert-butyl 2-{3-[(1R,2R)-2-amino-1,2-diphenylethyl]thioureido}succinate In chloroform at 80℃; for 72h; Michael reaction; optical yield given as %ee; enantioselective reaction; | 100% |
With 1-((1R,2R)-2-aminocyclohexyl)-3-(((1R,4aS,10ar)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)thiourea; p-Toluic acid In dichloromethane at 25℃; for 168h; Michael Addition; enantioselective reaction; | 80% |
Conditions | Yield |
---|---|
In ethanol for 6h; Reflux; | 100% |
Conditions | Yield |
---|---|
In ethanol for 6h; Reflux; | 100% |
Conditions | Yield |
---|---|
With cyclohexane at 105℃; for 1h; Dean-Stark; | 100% |
Conditions | Yield |
---|---|
Stage #1: 1-bromo-1-propene With magnesium In tetrahydrofuran Stage #2: (4-nitrophenyl)ethanone at 20℃; Cooling with ice; | 100% |
ethane-1,2-dithiol
(4-nitrophenyl)ethanone
2-methyl-2-(4-nitrophenyl)-1,3-dithiolane
Conditions | Yield |
---|---|
With amberlyst-15 In acetonitrile for 1h; | 99.95% |
In hexane for 1h; Reflux; | 99% |
With 9,10-dihydro-10-methylacridine at 50℃; for 36h; Green chemistry; | 86% |
1.3-propanedithiol
(4-nitrophenyl)ethanone
2-methyl-2-(4-nitrophenyl)-1,3-dithiane
Conditions | Yield |
---|---|
With amberlyst-15 In acetonitrile for 1h; | 99.95% |
With sulfamic acid functionalized magnetic Fe3O4 nanoparticles In neat (no solvent) at 25℃; for 2h; | 94% |
With magnesium hydrogen sulfate In acetonitrile at 80℃; for 10h; chemoselective reaction; | 93% |
trimethylsilyl cyanide
(4-nitrophenyl)ethanone
2-(4-nitro-phenyl)-2-hydroxypropanenitrile
Conditions | Yield |
---|---|
With titanium tetrachloride In dichloromethane at 20℃; for 18h; | 99.7% |
With titanium tetrachloride In dichloromethane at 20℃; for 18h; | 99.69% |
With titanium tetrachloride 1.) CH2Cl2, 0 deg C; 2.) CH2Cl2, RT, 24 h; | 45% |
IUPAC Name: 1-(4-Nitrophenyl)ethanone
Product Categories: Aromatic Acetophenones & Derivatives (substituted);C7 to C8;Carbonyl Compounds;Ketones
Synonyms of p-Nitroacetophenone (CAS NO.100-19-6): 4'-Nitroacetophenone ; 4-Nitroacetophenone ; Ethanone, 1-(4-nitrophenyl)- ; Methyl-p-nitrophenyl ketone ; Paranitroacetophenone ; p-Acetylnitrobenzene ; p-Nitrophenyl methyl ketone ; Acetophenone, 4'-nitro- ; Ethanone, 1-(4-nitrophenyl)- (9CI)
CAS NO: 100-19-6
Molecular Formula: C8H7NO3
Molecular Weight : 165.1461
Molecular Structure:
EINECS: 202-827-4
H bond acceptors: 4
H bond donors: 0
Freely Rotating Bonds: 2
Polar Surface Area: 62.89 Å2
Index of Refraction: 1.558
Molar Refractivity: 42.82 cm3
Molar Volume: 132.8 cm3
Surface Tension: 47.1 dyne/cm
Density: 1.243 g/cm3
Flash Point: 129.4 °C
Enthalpy of Vaporization: 51.38 kJ/mol
Boiling Point: 275.4 °C at 760 mmHg
Vapour Pressure: 0.00511 mmHg at 25°C
Melting Point: 75-78 °C(lit.)
Appearance: P-Nitroacetophenone (CAS NO.100-19-6) is yellow prisms or bright yellow powder.
Solubility: Insoluble in water,soluble in hot ethanol, ether and benzene.
P-Nitroacetophenone (CAS NO.100-19-6) is used as intermediate of pharmaceutical Chloramphenicol and dye intermediate.
Hazard Codes: Xn
Risk Statements: 36-22
R22: Harmful if swallowed.
R36: Irritating to eyes.
Safety Statements: 22-24/25
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: AM9627000
Hazard Note: Harmful
HS Code: 29147090
Mutation data reported. A flammable liquid. When heated to decomposition it emits toxic vapors of NOx.
DOT Classification: 3; Label: Flammable Liquid
p-Nitroacetophenone (CAS NO.100-19-6) is a nitrated ketone which is reactive with many acids and bases liberating heat and flammable gases (e.g., H2). The amount of heat may be sufficient to start a fire in the unreacted portion of the ketone. Ketones also react with reducing agents such as hydrides, alkali metals, and nitrides to produce flammable gas (H2) and heat. They react violently with aldehydes, HNO3, HNO3 + H2O2, and HClO4.Ketones are incompatible with isocyanates, aldehydes, cyanides, peroxides, and anhydrides.
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