4-Aminobenzyl alcohol

The IUPAC name of Benzenemethanol,4-amino- is (4-aminophenyl)methanol. With the CAS registry number 623-04-1, it is also named as 4-(Hydroxymethyl)aniline. The product's categories are fine chemical & intermediates; benzhydrols, benzyl & special alcohols. It is white to light yellow crystalline powder which is combustible and stable, but air and light sensitive. Additionally, this chemical should be sealed in the container and stored at cool and dry place. Keep it away from oxidizing agents and acid.

The other characteristics of this product can be summarized as: (1)ACD/LogP: -0.25; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.28; (4)ACD/LogD (pH 7.4): -0.25; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 16.22; (8)ACD/KOC (pH 7.4): 17.46; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.617; (12)Molar Refractivity: 36.94 cm³; (13)Molar Volume: 105.5 cm³; (14)Polarizability: 14.64×10^-24 cm³; (15)Surface Tension: 54.4 dyne/cm; (16)Enthalpy of Vaporization: 55.32 kJ/mol; (17)Vapour Pressure: 0.00137 mmHg at 25°C; (18)Rotatable Bond Count: 1; (19)Exact Mass: 123.068414; (20)MonoIsotopic Mass: 123.068414; (21)Topological Polar Surface Area: 46.2; (22)Heavy Atom Count: 9.

Preparation of Benzenemethanol,4-amino-: It can be obtained by (4-nitro-phenyl)-methanol. This reaction needs reagent Ba(BH2S3)2 and solvent tetrahydrofuran by heating. The reaction time is 1.75 hours. The yield is 85%. 

Uses of Benzenemethanol,4-amino-: It reacts 6-chloro-1H-pyrimidine-2,4-dione to get 6-(4-hydroxymethyl-phenylamino)-1H-pyrimidine-2,4-dione. This reaction needs reagent bis-(2-methoxy-ethyl) ether by heating. The yield is 75%.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed. And it is also irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
1. SMILES:OCc1ccc(N)cc1
2. InChI:InChI=1/C7H9NO/c8-7-3-1-6(5-9)2-4-7/h1-4,9H,5,8H2 
3. InChIKey:AXKGIPZJYUNAIW-UHFFFAOYAG