• Name

  4-Bromo-2-Indanone

• EINECS
• CAS No. 846032-36-8
• Article Data3
• CAS DataBase
• Density 1.608g/cm3
• Solubility
• Melting Point
• Formula C9H7 Br O
• Boiling Point 312.2ºC at 760 mmHg
• Molecular Weight 211.058
• Flash Point 126.3ºC
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms 4-bromo-2-indanone;4-Bromo-1,3-dihydro-2H-inden-2-one;4-BROMO-INDAN-2-ONE;2-INDANONE,4-BROMO;4-Bromo-1H-inden-2(3H)-one;
• PSA 17.07000
• LogP 2.11680

Synthetic route

16657-07-1

4-bromo-3H-indene

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

Conditions

Conditions	Yield
Stage #1: 4-bromo-3H-indene With 4-methylmorpholine N-oxide; osmium(VIII) oxide Stage #2: With toluene-4-sulfonic acid

125114-82-1

C9H7BrO

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

Conditions

Conditions	Yield
With zinc(II) iodide In benzene at 0 - 20℃; Product distribution / selectivity; Inert atmosphere;

125114-77-4

7-bromo-2,3-dihydro-1H-inden-1-one

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: sodium tetrahydroborate / ethanol; dichloromethane / 3 h / 0 - 20 °C 2: toluene-4-sulfonic acid / toluene / 0.5 h / Reflux 3: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C 4: zinc(II) iodide / toluene / 4 h / 0 - 20 °C View Scheme

rac-7-bromo-2,3-dihydro-1H-inden-1-ol

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: toluene-4-sulfonic acid / toluene / 0.5 h / Reflux 2: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C 3: zinc(II) iodide / toluene / 4 h / 0 - 20 °C View Scheme

45738-35-0

4-bromo-indene

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3 h / 0 - 20 °C 2: zinc(II) iodide / toluene / 4 h / 0 - 20 °C View Scheme

C9H7BrO

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

Conditions

Conditions	Yield
With zinc(II) iodide In toluene at 0 - 20℃; for 4h;

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

943749-58-4

8-bromo-1,4-dihydro-2H-isoquinolin-3-one

Conditions

Conditions	Yield
With hydrogenchloride; sodium azide at 0 - 12℃; for 12.3333h;	33%

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

846032-40-4

4-bromo-2,2-difluoro-indan

Conditions

Conditions	Yield
With diethylamino-sulfur trifluoride

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

123324-71-0

4-tert-butylphenylboronic acid

4-(4-t-butylphenyl)-2-indanone

Conditions

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; water; toluene at 80℃; for 16h;

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

A

2-[2-(5-methylfuryl)]-4-(4-t-butylphenyl)indene

B

C24H24O

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; toluene; water / 16 h / 80 °C 2.1: n-butyllithium / tetrahydrofuran / 4 h / -25 - 20 °C 2.2: 16 h / -25 - 20 °C 2.3: 0.17 h / Reflux View Scheme

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

bis(2-[2-(5-methylfuryl)]-4-(4-t-butylphenyl)inden-1-yl)(6-t-butoxyhexyl)methylsilane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; toluene; water / 16 h / 80 °C 2.1: n-butyllithium / tetrahydrofuran / 4 h / -25 - 20 °C 2.2: 16 h / -25 - 20 °C 2.3: 0.17 h / Reflux 3.1: n-butyllithium / tetrahydrofuran / 3 h / -25 - 20 °C 3.2: 15 h / 0 - 20 °C View Scheme

846032-36-8

4-bromo-1,3-dihydro-2H-inden-2-one

3-oxo-1,2,3,4-tetrahydroisoquinoline-8-carbonitrile

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium azide; hydrogenchloride / 12.33 h / 0 - 12 °C 2: tetrakis(triphenylphosphine) palladium(0) / N,N-dimethyl-formamide / 6 h / 150 °C / Inert atmosphere View Scheme

4-Bromo-2-Indanone Chemical Properties