Product Name

  • Name

    4-Fluoroacetanilide

  • EINECS 206-515-9
  • CAS No. 351-83-7
  • Article Data158
  • CAS DataBase
  • Density 1.1655 (estimate)
  • Solubility Water Solubility : practically insoluble
  • Melting Point 153-155 ºC
  • Formula C8H8 F N O
  • Boiling Point 300.6±25.0 °C(Predicted)
  • Molecular Weight 153.156
  • Flash Point
  • Transport Information
  • Appearance Off-white powder.
  • Safety 26-37/39-24/25
  • Risk Codes 36/37/38
  • Molecular Structure Molecular Structure of 351-83-7 (4-Fluoroacetanilide)
  • Hazard Symbols IrritantXi
  • Synonyms Acetanilide,4'-fluoro- (6CI,7CI,8CI); 4-Fluoroacetanilide; 4'-Fluoroacetanilide;N-(4-Fluorophenyl)acetamide; N-p-Fluorophenylacetamide; NSC 10349;p-Fluoroacetanilide
  • PSA 29.10000
  • LogP 1.85710

4-Fluoroacetanilide Chemical Properties

Product Name: 4-Fluoroacetanilide (CAS NO.351-83-7)


Molecular Formula: C8H8FNO
Molecular Weight: 153.15g/mol
Mol File: 351-83-7.mol
EINECS: 206-515-9
Melting Point: 153-155 °C(lit.)
Boiling point: 300.6 °C at 760 mmHg
Flash Point: 135.6 °C
Density: 1.208 g/cm3
Water Solubility: practically insoluble
Surface Tension: 39.7 dyne/cm
Enthalpy of Vaporization: 54.07 kJ/mol
Vapour Pressure: 0.00111 mmHg at 25°C
XLogP3-AA: 1.5
H-Bond Donor: 1
H-Bond Acceptor: 2
Structure Descriptors of 4-Fluoroacetanilide (CAS NO.351-83-7):
  IUPAC Name: N-(4-fluorophenyl)acetamide
  Canonical SMILES: CC(=O)NC1=CC=C(C=C1)F
  InChI: InChI=1S/C8H8FNO/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5H,1H3,(H,10,11) 
  InChIKey: JHEFOJNPLXSWNZ-UHFFFAOYSA-N
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts; Anilines, Amides & Amines;Fluorine Compounds

4-Fluoroacetanilide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo oral 250mg/kg (250mg/kg)   Journal of the American Pharmaceutical Association. Vol. 28, Pg. 70, 1939.
mouse LD50 oral > 3gm/kg (3000mg/kg)   French Demande Patent Document. Vol. #2081563,

4-Fluoroacetanilide Safety Profile

Safety Information of 4-Fluoroacetanilide (CAS NO.351-83-7):
Hazard Codes: XiIrritant
Risk Statements: 36/37/38 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 26-37/39-24/25-36
24:  Avoid contact with skin 
25:  Avoid contact with eyes 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing  
37:  Wear suitable gloves  
39:  Wear eye/face protection 
RTECS: AE2977000
Hazard Note: Irritant
HazardClass: IRRITANT

4-Fluoroacetanilide Specification

 4-Fluoroacetanilide , its CAS NO. is 351-83-7, the synonyms are AI3-52222 ; BRN 2208090 ; EINECS 206-515-9 ; N-(4-Fluorophenyl)acetamide ; N-p-Fluorophenylacetamide ; NSC 10349 ; p-Fluoroacetanilide ; Acetamide, N-(4-fluorophenyl)- (9CI) ; Acetanilide, 4'-fluoro- ; N-(4-Fluorophenyl)acetamide .

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