4-Hydroxy-3,5-dimethylbenzoic acid supplier

Name
4-Hydroxy-3,5-dimethylbenzoic acid
EINECS
CAS No. 4919-37-3
Article Data21
CAS DataBase
Density 1.249g/cm³
Solubility
Melting Point 221-226 ºC
Formula C9H10 O3
Boiling Point 331.3°Cat760mmHg
Molecular Weight 166.177
Flash Point 168.4°C
Transport Information
Appearance off-white to light pink or light beige crystalline
Safety Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26
RTECS DG8997500
Risk Codes R36/37/38
Molecular Structure
Hazard Symbols
Synonyms 2,6-Dimethyl-4-carboxyphenol;3,5-Dimethyl-4-hydroxybenzoic acid; 4-Hydroxy-3,5-dimethylbenzoic acid; NSC68319
PSA 57.53000
LogP 1.70720

Synthetic route

: 21553-46-8
4-methoxy-3,5-dimethylbenzoic acid

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With pyridine hydrochloride at 200℃; for 0.5h; Microwave irradiation; Ionic liquid;	96%
With hydrogen bromide

: 97888-80-7
3,5-dimethyl-4-benzyloxy-benzoic acid

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With tetrabutylammomium bromide; hydrogen bromide In dichloromethane for 24h; Heating;	87.3%

: 67-56-1
methanol

: 99-96-7
4-hydroxy-benzoic acid

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
at 40 - 60℃; Microwave irradiation;	85%

: 201230-82-2
carbon monoxide

: 10570-67-9
4-iodo-2,6-dimethylphenol

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With water; potassium carbonate at 100℃; for 24h;	79%

: 124-38-9
carbon dioxide

: 10570-67-9
4-iodo-2,6-dimethylphenol

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
Stage #1: 4-iodo-2,6-dimethylphenol With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.333333h; Stage #2: carbon dioxide In tetrahydrofuran; hexane at -78℃; for 0.5h;	41%

: 576-26-1
2.6-dimethylphenol

: 124-38-9
carbon dioxide

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
Stage #1: 2.6-dimethylphenol With sodium hydride Stage #2: carbon dioxide Kolbe-Schmidt reaction;	34%
(i) NaOMe, (ii) /BRN= 1900390/; Multistep reaction;

: 527-60-6
Mesitol

A: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

B: 6245-04-1
3,5-dimethylsalicylic acid

Conditions

Conditions	Yield
With potassium carbonate beim Schmelzen;

: 2233-18-3
4-hydroxy-3,5-dimethylbenzaldehyde

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With sodium hydroxide; silver(l) oxide

: 4919-40-8
4-amino-3,5-dimethylbenzoic acid

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With potassium nitrite; sulfuric acid
With copper(II) sulfate Diazotization;

: 527-60-6
Mesitol

potassium hydroxide: potassium hydroxide

A: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

B: 6245-04-1
3,5-dimethylsalicylic acid

Conditions

Conditions	Yield
beim Schmelzen;

...Expand

: 2233-18-3
4-hydroxy-3,5-dimethylbenzaldehyde

potash: potash

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
beim Schmelzen;

3.5-dimethyl-benzoic acid sulfamide-(4): 3.5-dimethyl-benzoic acid sulfamide-(4)

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With potassium carbonate beim Schmelzen;
With sodium hydroxide beim Schmelzen;

: 124-38-9
carbon dioxide

: 16081-16-6
sodium 2,6-dimethylphenolate

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

: 4919-40-8
4-amino-3,5-dimethylbenzoic acid

: 7782-77-6
cis-nitrous acid

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

4-oxy-3.5-dimethyl-benzaldehyde: 4-oxy-3.5-dimethyl-benzaldehyde

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
With potassium hydroxide

: 4198-90-7
3,5-dimethyl-4-hydroxybenzonitrile

KOH: KOH

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
beim Schmelzen;

: 3,5-dimethyl-4-sulfamoyl-benzoic acid

potassium hydroxide: potassium hydroxide

: 4919-37-3
3,5-dimethyl-4-hydroxybenzoic acid

Conditions

Conditions	Yield
gelindes Schmelzen;

4-Hydroxy-3,5-dimethylbenzoic acid Chemical Properties

Molecular structure of 4-Hydroxy-3,5-dimethylbenzoic acid (CAS NO.4919-37-3) is:

Product Name: 4-Hydroxy-3,5-dimethylbenzoic acid
CAS Registry Number: 4919-37-3
IUPAC Name: 4-Hydroxy-3,5-dimethylbenzoic acid
Molecular Weight: 166.1739 [g/mol]
Molecular Formula: C₉H₁₀O₃
XLogP3: 0.9
H-Bond Donor: 2
H-Bond Acceptor: 3
Melting Point: 221-226 °C
Index of Refraction: 1.587
Molar Refractivity: 44.71 cm³
Molar Volume: 132.9 cm³
Surface Tension: 53.5 dyne/cm
Density: 1.249 g/cm³
Flash Point: 168.4 °C
Enthalpy of Vaporization: 60.58 kJ/mol
Boiling Point: 331.3 °C at 760 mmHg
Vapour Pressure: 6.29E-05 mmHg at 25 °C
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
Canonical SMILES: CC1=CC(=CC(=C1O)C)C(=O)O
InChI: InChI=1S/C9H10O3/c1-5-3-7(9(11)12)4-6(2)8(5)10/h3-4,10H,1-2H3,(H,11,12)
InChIKey: OMNHTTWQSSUZHO-UHFFFAOYSA-N

4-Hydroxy-3,5-dimethylbenzoic acid Safety Profile

Safty information about 4-Hydroxy-3,5-dimethylbenzoic acid (CAS NO.4919-37-3) is:
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 37/39-26
S37/39:Wear suitable gloves and eye/face protection.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RTECS: DG8997500

4-Hydroxy-3,5-dimethylbenzoic acid Specification

4-Hydroxy-3,5-dimethylbenzoic acid , its cas register number is 4919-37-3. It also can be called Benzoic acid,4-hydroxy-3,5-dimethyl- .It is a off-white to light pink or light beige crystalline.

Product Name

4-Hydroxy-3,5-dimethylbenzoic acid

Synthetic route

4-Hydroxy-3,5-dimethylbenzoic acid Chemical Properties

4-Hydroxy-3,5-dimethylbenzoic acid Safety Profile

4-Hydroxy-3,5-dimethylbenzoic acid Specification

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Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	37/39-26
RTECS	DG8997500