• Name

  4-Methoxy-1-butanol

• EINECS 203-858-6
• CAS No. 111-32-0
• Article Data30
• CAS DataBase
• Density 0.906 g/cm³
• Solubility Slightly soluble in water.
• Melting Point
• Formula C₅H₁₂O₂
• Boiling Point 165.7 °C at 760 mmHg
• Molecular Weight 104.149
• Flash Point 54.1 °C
• Transport Information UN 1993
• Appearance
• Safety 26-36/37/39
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols F
• Synonyms 4-Methoxybutyl alcohol;Dowanol BMAT;NSC 245191;
• PSA 29.46000
• LogP 0.40530

Synthetic route

110-63-4

Butane-1,4-diol

74-88-4

methyl iodide

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With mercury(II) oxide In dichloromethane at 20℃; for 28h;	78%
(i) TlOEt, benzene, (ii) /BRN= 969135/, MeCN; Multistep reaction;
With thallium (I) ethoxide 1) MeCN, r.t., 2) MeCN, 20 deg C, 14 h; Yield given. Multistep reaction;

O-methyltetrahydrofuranium perchlorate

A

109-99-9

tetrahydrofuran

B

67-56-1

methanol

C

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With perchloric acid; sodium perchlorate; water at 25℃;	A n/a B n/a C 98%

...Expand

186581-53-3, 908094-01-9

diazomethane

A

67-56-1

methanol

B

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With perchloric acid; sodium perchlorate; water In tetrahydrofuran at 25℃; Product distribution; Kinetics; Rate constant; pH 4.0; reaction with different pH;	A 88% B 12%

505-65-7

1,3-dioxepane

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With diisobutylaluminium hydride In benzene for 2h; Heating;	90%
With lithium aluminium tetrahydride; boron trichloride 1.) CH2Cl2, 0.2 h, 2.) Et2O, 30 min; Yield given. Multistep reaction;

29006-01-7

Methyl 4-methoxybutyrate

762-72-1

allyl-trimethyl-silane

A

111-32-0

4-methoxybutanol

B

1238320-08-5

7-methoxy-1-hepten-4-ol

Conditions

Conditions	Yield
With indium (III) iodide; Dimethylphenylsilane In dichloromethane at 20℃; for 3h; Inert atmosphere; chemoselective reaction;	A 11 %Spectr. B 50%

...Expand

110-63-4

Butane-1,4-diol

77-78-1

dimethyl sulfate

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In hexane; water for 6h;	80%

3276-41-3

2-nitroso-3,6-dihydro-2H-[1,2]oxazine

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With hydrogen; nickel In methanol

98-01-1

furfural

67-56-1

methanol

A

97-99-4

Tetrahydrofurfuryl alcohol

B

19354-27-9

methyl tetrahydrofurfuryl ether

C

111-89-7

1,5-dimethoxypentane

D

111-32-0

4-methoxybutanol

E

4799-62-6

O-methyl-pentamethylene glycol

F

13679-46-4

2-(methoxymethyl)furan

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen at 170℃; under 52505.3 Torr; for 2h; Autoclave;	A 44.3% B 8.4% C n/a D n/a E n/a F n/a

...Expand

928-51-8

4-Chloro-1-butanol

124-41-4

sodium methylate

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
In methanol Heating;	82%

696-59-3

cis,trans-2,5-dimethoxytetrahydrofuran

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride; aluminium trichloride In tetrahydrofuran

74-87-3

methylene chloride

C4H9O2(1-)

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
at 76.84℃; under 3E-07 - 5E-06 Torr; Kinetics;

50-00-0

formaldehyd

magnesium compound of 3-chloro-1-methoxy-propane

magnesium compound of 3-chloro-1-methoxy-propane

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With diethyl ether; zinc(II) chloride
With benzene

33691-61-1

3-bromo-2-methoxy-tetrahydrofuran

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride; aluminium trichloride for 10h;

74-88-4

methyl iodide

sodium-<4-hydroxy-butylate>

sodium-<4-hydroxy-butylate>

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With Butane-1,4-diol; toluene

4696-30-4

methoxy-1 butene-3

A

41223-27-2

propylene glycol methyl ether

B

111-32-0

4-methoxybutanol

Conditions

Conditions	Yield
With sodium hydroxide; sodium tetrahydroborate; mercury(II) diacetate In tetrahydrofuran; water Product distribution; 1) 30 min, 2) ca. 0.5 h;
With sodium hydroxide; sodium tetrahydroborate; mercury(II) diacetate 1) 30 min, 2) aq. NaOH, NaBH4; Yield given. Multistep reaction. Yields of byproduct given;

potassium 4-hydroxy-1-butoxide

74-88-4

methyl iodide

111-32-0

4-methoxybutanol

4-Methoxy-1-butanol Chemical Properties

4-Methoxy-1-butanol Toxicity Data With Reference

4-Methoxy-1-butanol Safety Profile

4-Methoxy-1-butanol Specification