5-Methyl-3-phenylisoxazole-4-carboxylic acid supplier

Name
5-Methyl-3-phenylisoxazole-4-carboxylic acid
EINECS 214-497-9
CAS No. 1136-45-4
Article Data26
CAS DataBase
Density 1.273g/cm³
Solubility
Melting Point 192-194 °C(lit.)
Formula C₁₁H₉NO₃
Boiling Point 365 °C at 760 mmHg
Molecular Weight 203.197
Flash Point 174.5 °C
Transport Information
Appearance cream to pale brown solid
Safety 24/25-36/37-22
Risk Codes 22
Molecular Structure
Hazard Symbols Xi
Synonyms 3-Phenyl-5-methylisoxazole-4-carboxylicacid;4-Carboxy-5-methyl-3-phenylisoxazole;NSC 76870;
PSA 63.33000
LogP 2.34820

5-Methyl-3-phenylisoxazole-4-carboxylic acid Chemical Properties

Molecular structure of 5-Methyl-3-phenylisoxazole-4-carboxylic acid (CAS NO.1136-45-4) is:

Product Name: 5-Methyl-3-phenylisoxazole-4-carboxylic acid
CAS Registry Number: 1136-45-4
IUPAC Name: 5-methyl-3-phenyl-1,2-oxazole-4-carboxylic acid
Molecular Weight: 203.19406 [g/mol]
Molecular Formula: C₁₁H₉NO₃
XLogP3-AA: 2
H-Bond Donor: 1
H-Bond Acceptor: 4
EINECS: 214-497-9
Melting Point: 192-194 °C(lit.)
Surface Tension: 52 dyne/cm
Density: 1.273 g/cm³
Flash Point: 174.5 °C
Enthalpy of Vaporization: 64.49 kJ/mol
Boiling Point: 365 °C at 760 mmHg
Vapour Pressure: 5.74E-06 mmHg at 25°C
Product Categories: Heterocyclic Series;Oxazole&Isoxazole;Organic acids;Oxacilline;Building Blocks;Heterocyclic Building Blocks;Isoxazoles

5-Methyl-3-phenylisoxazole-4-carboxylic acid Uses

5-Methyl-3-phenylisoxazole-4-carboxylic acid (CAS NO.1136-45-4) can be used for the production of sodium oxacillin.

5-Methyl-3-phenylisoxazole-4-carboxylic acid Production

5-Methyl-3-phenylisoxazole-4-carboxylic acid (CAS NO.1136-45-4) can be derived by the reaction of cyclization of the benzyl chloride and acetyl ethyl oxime and then hydrolysis.

5-Methyl-3-phenylisoxazole-4-carboxylic acid Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	300mg/kg (300mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 322, 1965.
rat	LD50	intraperitoneal	1500mg/kg (1500mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 781, 1962.

5-Methyl-3-phenylisoxazole-4-carboxylic acid Consensus Reports

Reported in EPA TSCA Inventory.

5-Methyl-3-phenylisoxazole-4-carboxylic acid Safety Profile

Hazard Codes: Irritant Xi
Risk Statements: 22
R22:Harmful if swallowed.
Safety Statements: 24/25-36/37-22
S24/25:Avoid contact with skin and eyes.
S36/37:Wear suitable protective clothing and gloves.
S22:Do not breathe dust.
WGK Germany: 3
RTECS: NY2750000
HazardClass: IRRITANT

5-Methyl-3-phenylisoxazole-4-carboxylic acid Specification

5-Methyl-3-phenylisoxazole-4-carboxylic acid , its cas register number is 1136-45-4. It also can be called 3-Phenyl-5-methylisoxazol-4-carbonsaeure ; 3-Phenyl-5-methylisoxazole-4-carboxylic acid ; Isoxazole-4-carboxylic acid, 5-methyl-3-phenyl- ; 4-Isoxazolecarboxylic acid, 5-methyl-3-phenyl- .It is a cream to pale brown solid.

Product Name

5-Methyl-3-phenylisoxazole-4-carboxylic acid