-
Name
Etifoxine
- EINECS
- CAS No. 21715-46-8
- Article Data2
- CAS DataBase
- Density 1.2g/cm3
- Solubility
- Melting Point 90-92℃
- Formula C17H17 Cl N2 O
- Boiling Point 421.2°Cat760mmHg
- Molecular Weight 300.788
- Flash Point 208.5°C
- Transport Information
- Appearance
- Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. A tranquilizer. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 4H-3,1-Benzoxazine,6-chloro-2-(ethylamino)-4-methyl-4-phenyl- (8CI); 2-Ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine;Etifoxin; Etifoxine; HOE 36-801
- PSA 33.62000
- LogP 4.05720
6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine Chemical Properties
IUPAC Name: 6-chloro-N-ethyl-4-methyl-4-phenyl-3,1-benzoxazin-2-amine
Empirical Formula: C17H17ClN2O
Molecular Weight: 300.7827g/mol
Structure of 6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine (CAS NO.21715-46-8):
.bmp)
Index of Refraction: 1.601
Molar Refractivity: 85.5 cm3
Molar Volume: 249.5 cm3
Polarizability: 33.89×10-24cm3
Surface Tension: 41.5 dyne/cm
Density: 1.2 g/cm3
Flash Point: 208.5 °C
Enthalpy of Vaporization: 67.51 kJ/mol
Boiling Point: 421.2 °C at 760 mmHg
Vapour Pressure: 2.66E-07 mmHg at 25°C
Classification Code: Anti-Anxiety Agents, Central Nervous System Agents, Central Nervous System Depressants, Drug / Therapeutic Agent, Psychotropic Drugs, Tranquilizing Agents
Canonical SMILES: CCNC1=NC2=C(C=C(C=C2)Cl)C(O1)(C)C3=CC=CC=C3
InChI: InChI=1S/C17H17ClN2O/c1-3-19-16-20-15-10-9-13(18)11-14(15)17(2,21-16)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3,(H,19,20)
InChIKey: IBYCYJFUEJQSMK-UHFFFAOYSA-N
6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine Toxicity Data With Reference
| 1. | orl-rat LD50:1500 mg/kg | THERAP Therapie. 27 (1972),325. | ||
| 2. | ipr-rat LD50:292 mg/kg | THERAP Therapie. 27 (1972),325. | ||
| 3. | ivn-rat LD50:55 mg/kg | THERAP Therapie. 27 (1972),325. | ||
| 4. | orl-mus LD50:1388 mg/kg | THERAP Therapie. 27 (1972),325. | ||
| 5. | ipr-mus LD50:450 mg/kg | THERAP Therapie. 27 (1972),325. | ||
| 6. | ivn-mus LD50:120 mg/kg | THERAP Therapie. 27 (1972),325. | ||
| 7. | ivn-gpg LDLo:133 mg/kg | THERAP Therapie. 27 (1972),325. |
6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine Safety Profile
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. A tranquilizer. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine Specification
6-Chloro-2-ethylamino-4-methyl-4-phenyl-4H-3,1-benzoxazine , its cas register number is 21715-46-8. It also can be called 2-Aethylamino-6-chlor-4-methyl-4-phenyl-4H-3,1-benzoxazin ; BRN 0548223 ; Etifoxin ; Etifoxina ; Etifoxine ;
Etifoxinum ; HOE 36801 ; UNII-X24X82MX4X .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View