7-Anilino-4-hydroxy-2-naphthalenesulfonic acid supplier

Name
7-Anilino-4-hydroxy-2-naphthalenesulfonic acid
EINECS 204-320-3
CAS No. 119-40-4
Article Data5
CAS DataBase
Density 1.495 g/cm³
Solubility 587.97mg/L at 25℃
Melting Point
Formula C₁₆H₁₃NO₄S
Boiling Point
Molecular Weight 315.35
Flash Point
Transport Information
Appearance
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1-Naphthol-3-sulfonicacid, 6-anilino- (5CI);2-Naphthalenesulfonic acid, 7-anilino-4-hydroxy-(7CI,8CI);1-Hydroxy-6-anilinonaphthalene-3-sulfonic acid;2-Anilino-5-naphthol-7-sulfonicacid;2-Phenylamino-5-naphthol-7-sulfonic acid;4-Hydroxy-7-(phenylamino)-2-naphthalenesulfonic acid;6-(Phenylamino)-1-naphthol-3-sulfonic acid;6-Phenylamino-1-hydroxynaphthalene-3-sulfonic acid;7-Anilino-4-hydroxy-2-naphthalenesulfonic acid;N-Phenyl I acid;N-Phenyl Jacid;NSC 1745;NSC 37153;
PSA 95.01000
LogP 4.68950

Synthetic route

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 62-53-3
aniline

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

Conditions

Conditions	Yield
With sodium metabisulfite at 100 - 110℃; pH=4-6; Reagent/catalyst;	70.2%
With sodium disulfite

: 118-33-2
6-amino-naphthalene-1,3-disulfonic acid

: 62-53-3
aniline

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

Conditions

Conditions	Yield
With aniline hydrochloride man macht mit Soda alkalisch, dampft ein und erhitzt mit Kalilauge auf 210-220grad;

: 6357-94-4
4,7-dihydroxy-naphthalene-2-sulfonic acid

: 62-53-3
aniline

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

Conditions

Conditions	Yield
With ammonium sulfite

: 87-02-5
1-hydroxy-6-amino-3-naphthalenesulfonic acid

: 62-53-3
aniline

sodium disulfite: sodium disulfite

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

...Expand

: 62-53-3
aniline

naphthol-(2)-disulfonic acid-(5.7): naphthol-(2)-disulfonic acid-(5.7)

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

Conditions

Conditions	Yield
With aniline hydrochloride man macht mit Soda alkalisch, dampft ein und erhitzt mit Kalilauge auf 210-220grad;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 98-88-4
benzoyl chloride

: 4-(benzoyloxy)-7-(phenylamino)naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;	85%

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 3-{4-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazoline-6-diazonium

: 3-(3-{4-[(E)-2-(2,4-Dichloro-phenyl)-vinyl]-phenyl}-2-mercapto-4-oxo-3,4-dihydro-quinazolin-6-ylazo)-4-hydroxy-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium carbonate; sodium chloride In water 1.) 0-5 deg C, 3 h; 2.) 60 deg C;	84%

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 874-60-2
4-methyl-benzoyl chloride

: 4-(4-methylbenzoyloxy)-7-(phenylamino)naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;	82%

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 3282-30-2
pivaloyl chloride

: 4-(2,2-dimethylpropanoyloxy)-7-(phenylamino)naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;	80%

: 2736-40-5
chlorure d'acide ethyl-2 butyrique

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 4-(2-ethylbutanoyloxy)-7-(phenylamino)naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With triethylamine In ethyl acetate at 20℃; for 12h; Green chemistry;	78%

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 96-91-3
picramic acid

: C22H15N5O9S

Conditions

Conditions	Yield
Stage #1: picramic acid With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 1h; Stage #2: With aminosulfonic acid In water for 0.05h; Stage #3: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid In water at 10℃; for 2h;	3.4%

: 64-18-6
formic acid

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 7-(N-formyl-anilino)-4-hydroxy-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With sodium formate

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: diazonium chloride of 2-methyl-6-amino-4-oxoquinazoline

: Sodium; 4-hydroxy-3-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylazo)-7-phenylamino-naphthalene-2-sulfonate

Conditions

Conditions	Yield
With sodium carbonate In water at 0 - 5℃; for 3h;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 128031-43-6
6-Amino-2-{(E)-2-[4-((E)-styryl)-phenyl]-vinyl}-3H-quinazolin-4-one

: 4-Hydroxy-3-(4-oxo-2-{(E)-2-[4-((E)-styryl)-phenyl]-vinyl}-3,4-dihydro-quinazolin-6-ylazo)-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium carbonate; sodium nitrite 2.) from 0 to 5 deg C, 3 h; Multistep reaction;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 163732-38-5
6-Amino-2-((E)-2-{4-[(E)-2-(4-chloro-phenyl)-vinyl]-phenyl}-vinyl)-3H-quinazolin-4-one

: 3-[2-((E)-2-{4-[(E)-2-(4-Chloro-phenyl)-vinyl]-phenyl}-vinyl)-4-oxo-3,4-dihydro-quinazolin-6-ylazo]-4-hydroxy-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium carbonate; sodium nitrite 2.) from 0 deg C to 5 deg C, 3 h; Multistep reaction;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 179910-68-0
6-Amino-3-(4-chloro-phenyl)-2-mercapto-3H-quinazolin-4-one

: 3-[3-(4-Chloro-phenyl)-2-mercapto-4-oxo-3,4-dihydro-quinazolin-6-ylazo]-4-hydroxy-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium carbonate; sodium nitrite 2.) from 0 deg C to 5 deg C, 3 h; Multistep reaction;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 179910-67-9
6-Amino-3-(4-bromo-phenyl)-2-mercapto-3H-quinazolin-4-one

: 3-[3-(4-Bromo-phenyl)-2-mercapto-4-oxo-3,4-dihydro-quinazolin-6-ylazo]-4-hydroxy-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium carbonate; sodium nitrite 2.) from 0 deg C to 5 deg C, 3 h; Multistep reaction;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 179910-69-1
6-Amino-2-mercapto-3-(4-methoxy-phenyl)-3H-quinazolin-4-one

: 4-Hydroxy-3-[2-mercapto-3-(4-methoxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-6-ylazo]-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium carbonate; sodium nitrite 2.) from 0 deg C to 5 deg C, 3 h; Multistep reaction;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 179910-70-4
6-Amino-2-((E)-2-{4-[(E)-2-(4-dimethylamino-phenyl)-vinyl]-phenyl}-vinyl)-3H-quinazolin-4-one

: 3-[2-((E)-2-{4-[(E)-2-(4-Dimethylamino-phenyl)-vinyl]-phenyl}-vinyl)-4-oxo-3,4-dihydro-quinazolin-6-ylazo]-4-hydroxy-7-phenylamino-naphthalene-2-sulfonic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium carbonate; sodium nitrite 2.) from 0 deg C to 5 deg C, 3 h; Multistep reaction;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

tetrazotized 4.4'-diamino-diphenyl-dicarboxylic acid-(3.3'): tetrazotized 4.4'-diamino-diphenyl-dicarboxylic acid-(3.3')

: 4-(6-anilino-1-hydroxy-3-sulfo-[2]naphthylazo)-4'-(1-hydroxy-5-sulfo-[2]naphthylazo)-biphenyl-3,3'-dicarboxylic acid

Conditions

Conditions	Yield
With dicarbonate und Behandeln mit Naphthol-(1)-sulfonsaeure-(5) in sodaalkalischer Loesung bei Gegenwart von Pyridin;

: 1149376-22-6
C24H20N6O6S2

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 1149431-23-1
C40H30N8O10S3

Conditions

Conditions	Yield
Stage #1: C24H20N6O6S2 With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 25 - 30℃; for 2h; Stage #2: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With sodium carbonate In water pH=7 - 10;

: 1149376-32-8
C32H28N8O6S2

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: 1149431-29-7
C48H38N10O10S3

Conditions

Conditions	Yield
Stage #1: C32H28N8O6S2 With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 25 - 30℃; for 2h; Stage #2: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With sodium carbonate In water pH=7 - 10;

: C32H29N7O9S3

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: C48H39N9O13S4

Conditions

Conditions	Yield
Stage #1: C32H29N7O9S3 With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 20 - 30℃; for 1h; Stage #2: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With sodium carbonate In water pH=8-10;

: C39H43N7O11S3

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: C55H53N9O15S4

Conditions

Conditions	Yield
Stage #1: C39H43N7O11S3 With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 20 - 30℃; for 1h; Stage #2: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With sodium carbonate In water pH=8-10;

: C28H27N7O6S2

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: C44H37N9O10S3

Conditions

Conditions	Yield
Stage #1: C28H27N7O6S2 With sodium hydroxide In water Stage #2: With hydrogenchloride; sodium nitrite In water at 20 - 30℃; for 1h; Stage #3: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With sodium carbonate In water at 20 - 30℃; pH=8 - 10;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: C36H36N6O8S2

: C52H46N8O12S3

Conditions

Conditions	Yield
Stage #1: C36H36N6O8S2 With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 20 - 30℃; for 1h; Stage #2: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With sodium carbonate In water pH=8-10;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: C46H48N8O12S3

: C62H58N10O16S4

Conditions

Conditions	Yield
Stage #1: C46H48N8O12S3 With hydrogenchloride; sodium hydroxide; sodium nitrite In water at 20 - 30℃; for 1h; Stage #2: 2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid With hydrogenchloride; sodium carbonate In water pH=8-10;

: 119-40-4
2-phenylamino-5-hydroxynaphthalene-7-sulphonic acid

: C25H27N6O8S2(1+)*Cl(1-)

: C41H39N7O12S3

Conditions

Conditions	Yield
With sodium carbonate In water pH=8-10;

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid Chemical Properties

Product Name: 2-Naphthalenesulfonicacid, 4-hydroxy-7-(phenylamino)- (CAS NO.119-40-4)

Molecular Formula: C₁₆H₁₃NO₄S
Molecular Weight: 315.34g/mol
Mol File: 119-40-4.mol
EINECS: 204-320-3
Density: 1.495 g/cm³
Surface Tension: 75.1 dyne/cm
XLogP3-AA: 1.4
H-Bond Donor: 3
H-Bond Acceptor: 5
Structure Descriptors of 2-Naphthalenesulfonicacid, 4-hydroxy-7-(phenylamino)- (CAS NO.119-40-4):
IUPAC Name: 7-anilino-4-hydroxynaphthalene-2-sulfonic acid
Canonical SMILES: C1=CC=C(C=C1)NC2=CC3=CC(=CC(=C3C=C2)O)S(=O)(=O)O
InChI: InChI=1S/C16H13NO4S/c18-16-10-14(22(19,20)21)9-11-8-13(6-7-15(11)16)17-12-4-2-1-3-5-12/h1-10,17-18H,(H,19,20,21)
InChIKey: YGNDWDUEMICDLW-UHFFFAOYSA-N
Product Categories: Intermediates of Dyes and Pigments

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid Safety Profile

Safety Information of 2-Naphthalenesulfonicacid, 4-hydroxy-7-(phenylamino)- (CAS NO.119-40-4):
Safety Statements: 22-24/25
22: Do not breathe dust
24: Avoid contact with skin
25: Avoid contact with eyes

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid Specification

2-Naphthalenesulfonicacid, 4-hydroxy-7-(phenylamino)- , its CAS NO. is 119-40-4, the synonyms are 4-Hydroxy-7-(phenylamino)-2-naphthalenesulfonic acid ; 7-Anilino-4-hydroxy-2-naphthalenesulfonic acid ; Phenyl J Acid ; 2-Naphthalenesulfonic acid, 7-anilino-4-hydroxy- (8CI) .

Product Name

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid

Synthetic route

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid Chemical Properties

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid Safety Profile

7-Anilino-4-hydroxy-2-naphthalenesulfonic acid Specification

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