Amino-2-propanol

The 1-Amino-2-propanol with CAS registry number of 78-96-6 is also known as 1-Amino-2-hydroxypropane. The IUPAC name is 1-Aminopropan-2-ol. Its EINECS registry number is 201-162-7. In addition, the formula is C₃H₉NO and the molecular weight is 75.11. This chemical is a colorless or light yellow liquid and immiscible with water, ethanol phase and insoluble in ether.

Physical properties about 1-Amino-2-propanol are: (1)ACD/LogP: -0.96; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.03; (4)ACD/LogD (pH 7.4): -3.27; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 12.47Ų; (13)Index of Refraction: 1.439; (14)Molar Refractivity: 20.97 cm³; (15)Molar Volume: 79.6 cm³; (16)Polarizability: 8.31×10^-24cm³; (17)Surface Tension: 35.7 dyne/cm; (18)Density: 0.943 g/cm³; (19)Flash Point: 73.9 °C; (20)Enthalpy of Vaporization: 46.18 kJ/mol; (21)Boiling Point: 159.9 °C at 760 mmHg; (22)Vapour Pressure: 0.858 mmHg at 25 °C.

Preparation of 1-Amino-2-propanol: it is prepared by reaction of propylene oxide with ammonia. Mixing propylene oxide and ammonia. Preheating the mixture. After deamination, dehydration, vacuum distillation, distillation, product is obtained.

Uses of 1-Amino-2-propanol: it is used as solvents, surfactants, plasticizers, emulsifiers, antistatic agents in fiber industry and rubber vulcanization accelerator. This chemical also can be used as surfactants of raw materials, detergent and so on. What's more, it can be used to prepare non-water-soluble detergent such as dry cleaning products.

When you are using this chemical, please be cautious about it. As a chemical, it can cause burns. During using it, wear suitable protective clothing and do not breathe gas/fumes/vapour/spray. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, if accident happens or you feel unwell seek medical advice immediately.

You can still convert the following datas into molecular structure:
1. SMILES: OC(C)CN
2. InChI: InChI=1/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3
3. InChIKey: HXKKHQJGJAFBHI-UHFFFAOYAP
4. Std. InChI: InChI=1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3
5. Std. InChIKey: HXKKHQJGJAFBHI-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LD50	skin	> 1gm/kg (1000mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(7), Pg. 46, 1986.
mouse	LDLo	intraperitoneal	250mg/kg (250mg/kg)	BEHAVIORAL: EXCITEMENT	"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 4, Pg. 232, 1952.
rabbit	LD50	skin	1640uL/kg (1.64mL/kg)		Union Carbide Data Sheet. Vol. 5/21/1971,
rat	LD50	oral	1715mg/kg (1715mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(7), Pg. 46, 1986.