Batyl alcohol supplier | CasNO.544-62-7

Name
Batyl alcohol
EINECS 208-874-7
CAS No. 544-62-7
Article Data40
CAS DataBase
Density 0.914 g/cm³
Solubility
Melting Point 71-73 °C(lit.)
Formula C₂₁H₄₄O₃
Boiling Point 471.1 °C at 760 mmHg
Molecular Weight 344.579
Flash Point 238.7 °C
Transport Information
Appearance
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms (RS)-Batylalcohol;1-O-Octadecylglycerol;1-Octadecyloxy-2,3-dihydroxypropane;Batilalcohol;Glycerol 1-octadecyl ether;NikkolBatyl Alcohol 100;Nikkol Batyl Alcohol EX;Stearylmonoglyceride;a-Monostearyl glyceryl ether;
PSA 49.69000
LogP 5.61770

Synthetic route

: 16725-43-2
4-(n-octadecyloxymethyl)-2,2-dimethyl-1,3-dioxolane

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With hydrogenchloride In water for 4h; Reflux;	96%
With hydrogenchloride; methanol for 1h; Heating; Yield given;
With sulfuric acid In tetrahydrofuran at 100℃; for 2h;

: 112-61-8
Methyl stearate

: 56-81-5
glycerol

A: 544-62-7
batyl alcohol

B: 927-18-4
2-octadecyloxy-propane-1,3-diol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; camphor-10-sulfonic acid; hydrogen at 120℃; under 37503.8 Torr; for 16h; Autoclave; regioselective reaction;	A 73% B n/a

...Expand

: 25580-78-3
1-[(prop-2'-en-1'-yl)oxy]octadecane

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With cethyltrimethylammonium permanganate In dichloromethane at 20℃; for 5h; Addition;	65%
With Perbenzoic acid; chloroform at 70 - 80℃; beim folgenden Hydrolyse mit wss.-alkoh.H2SO4 oder KOH;
With formic acid; sulfuric acid; dihydrogen peroxide Erwaermen des Reaktionsprodukts mit wss.-aethanol.Kalilauge;
With dihydrogen peroxide; acetic acid at 70 - 80℃; beim folgenden Hydrolyse mit wss.-alkoh.H2SO4 oder KOH;

: 111-03-5, 2716-53-2, 30836-40-9, 34487-30-4, 69483-90-5, 99297-71-9, 129784-87-8
1-monooleoyl glycerol

: 56-81-5
glycerol

A: 544-62-7
batyl alcohol

B: 927-18-4
2-octadecyloxy-propane-1,3-diol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen at 120℃; under 37503.8 Torr; for 16h; Autoclave; regioselective reaction;	A 35% B n/a

...Expand

: 22610-63-5
octadecanoic acid 2,3-dihydroxypropyl ester

: 56-81-5
glycerol

A: 544-62-7
batyl alcohol

B: 927-18-4
2-octadecyloxy-propane-1,3-diol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen at 120℃; under 37503.8 Torr; for 16h; Autoclave; regioselective reaction;	A 34% B n/a

...Expand

: 57-11-4
stearic acid

: 56-81-5
glycerol

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; camphor-10-sulfonic acid; hydrogen at 20 - 140℃; under 37503.8 Torr; for 24h; Autoclave;	30%
With palladium on activated charcoal; hydrogen at 120℃; under 37503.8 Torr; for 16h; Autoclave; Inert atmosphere;	29%

: 31081-59-1
1-octadecyl methanesulfonate

: 100-79-8
(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
(i) K, benzene, (ii) /BRN= 1913366/, (iii) aq. HCl, MeOH; Multistep reaction;

: 3386-32-1
n-octadecyl p-toluenesulfonate

: 100-79-8
(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
(i) NaNH2, toluene, (ii) /BRN= 2011780/, (iii) aq. AcOH; Multistep reaction;

: 923-62-6
1,2-bis-octadecanoyloxy-3-octadecyloxy-propane

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With sodium hydroxide In methanol; chloroform

: 3386-32-1
n-octadecyl p-toluenesulfonate

: 33145-48-1
(2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol; sodium salt

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
(i) NaNH2, toluene, (ii) /BRN= 2011780/, toluene, (iii) aq. HCl, EtOH; Multistep reaction;

: 4,4'-(3-heptadecyl-2,4-dioxa-pentane-1,5-diyl)-bis-[1,3]dioxolan-2-one

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
(i) AcCl, (ii) Et3N, (iii) H2, NaHCO3, PtO2, Et2O; Multistep reaction;

: 16245-97-9
octadecyl glycidyl ether

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With perchloric acid In 1,4-dioxane; water pH 2;

glycerol-1-octadecyl ether-2.3-isopropylidene ether: glycerol-1-octadecyl ether-2.3-isopropylidene ether

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With acetic acid

O1,O2-isopropyliden-O3-octyl-glycerol: O1,O2-isopropyliden-O3-octyl-glycerol

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With acetic acid Erwaermen des Reaktionsprodukts mit wss.Natronlauge;
With hydrogenchloride

monosodium glycerate: monosodium glycerate

sodium octadecyl sulfate: sodium octadecyl sulfate

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With glycerol at 210 - 215℃;
With glycerol at 210 - 215℃;

: 67-56-1
methanol

: batyl alcohol-3-O-α-L-fucoside

A: 65310-00-1
(3S,4R,5S,6S)-2-methoxy-6-methyltetrahydro-2H-pyran-3,4,5-triol

B: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With sulfuric acid for 6h; Hydrolysis; methylation; etherification; Heating;	A n/a B 12 mg

...Expand

: 1116-44-5
α-O-(1-Octadecenyl)-β,α'-distearoyl-glycerin

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: H2 / Pd / cyclohexane 2: aq. NaOH / CHCl3; methanol View Scheme

: 112-89-0
1-Bromooctadecane

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrabutylammonium bromide; potassium hydroxide / 18 h / 35 - 40 °C 2: 903 mg / p-toluenesulfonic acid / tetrahydrofuran; H2O / Heating View Scheme
Multi-step reaction with 2 steps 1: NaH / dimethylformamide / 6 h / 60 °C 2: aq. H2SO4 / tetrahydrofuran / 2 h / 100 °C View Scheme
Multi-step reaction with 2 steps 1: sodium hydride / toluene / Inert atmosphere; Schlenk technique; Reflux 2: hydrogenchloride / water; methanol / 2 h / Inert atmosphere; Schlenk technique; Reflux View Scheme

: 3386-32-1
n-octadecyl p-toluenesulfonate

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 75 percent / NaH / tetrahydrofuran 2: aq. p-TsOH / tetrahydrofuran / Heating View Scheme
Multi-step reaction with 2 steps 1: NaH / dimethylformamide; petroleum ether / 50 °C 2: 1N HCl / dioxane / Heating View Scheme

: 112-92-5
1-octadecanol

CS2: CS2

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 73 percent / 48 percent aq. NaOH / TBAB / hexane / 6 h / 45 °C 2: 65 percent / cetyltrimethylammonium permanganate / CH2Cl2 / 5 h / 20 °C View Scheme

: 112-92-5
1-octadecanol

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: K2CO3 / benzene / 5 h / Heating 2: perchloric acid / dioxane; H2O / pH 2 View Scheme
Multi-step reaction with 3 steps 1: 76 percent / pyridine / 5 h / Ambient temperature 2: 1.) KOH / 1.) xylene, 1h, reflux; 2.) xylene, 5h, reflux 3: HCl/methanol / 1 h / Heating View Scheme
Multi-step reaction with 2 steps 1: Py 2: (i) K, benzene, (ii) /BRN= 1913366/, (iii) aq. HCl, MeOH View Scheme
Multi-step reaction with 3 steps 1.1: sodium hydroxide / neat (no solvent) / 7 h / 70 °C 1.2: 255 1.3: 255 2.1: 1,3-dimethylimidazolim iodide / toluene / 5 h 3.1: sodium hydroxide; ethanol View Scheme

: 31081-59-1
1-octadecyl methanesulfonate

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) KOH / 1.) xylene, 1h, reflux; 2.) xylene, 5h, reflux 2: HCl/methanol / 1 h / Heating View Scheme
With hydrogenchloride; potassium hydroxide In methanol; dimethyl sulfoxide

: 3386-33-2
1-chlorooctadecane

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 2: H2O2; glacial acetic acid / 70 - 80 °C / beim folgenden Hydrolyse mit wss.-alkoh.H2SO4 oder KOH View Scheme

: 629-93-6
n-iodooctadecane

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 60 - 65 °C 2: H2O2; glacial acetic acid / 70 - 80 °C / beim folgenden Hydrolyse mit wss.-alkoh.H2SO4 oder KOH View Scheme

: 1198155-32-6
2,3-dibutyroil-1-O-octadecyl glycerol

A: 544-62-7
batyl alcohol

B: 2-butyroyl-1-O-octadecyl glycerol

C: 107-92-6
butyric acid

Conditions

Conditions	Yield
Stage #1: 2,3-dibutyroil-1-O-octadecyl glycerol With pancreatin; sodium cholate; sodium cholate; sodium chloride; calcium chloride at 37℃; for 1h; pH=6.5 - 7.2; Trizma-maleate buffer; Stage #2: With hydrogenchloride In water

...Expand

: 40630-77-1, 113723-74-3
1-O-benzoyl3-O-octadecyl-sn-glycerol

: 544-62-7
batyl alcohol

Conditions

Conditions	Yield
With ethanol; sodium hydroxide

: 544-62-7
batyl alcohol

: 76-83-5
trityl chloride

: 86334-56-7
1-octadecyloxy-3-trityloxy-propan-2-ol

Conditions

Conditions	Yield
With pyridine for 48h; Ambient temperature;	100%
With pyridine at 70℃; for 24h;	96%
With pyridine

: 544-62-7
batyl alcohol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 115945-64-7
<(tert-butyl)dimethylsilyl>oxy-1-(octadecyloxy)-3-propanol-2

Conditions

Conditions	Yield
With 1H-imidazole In N,N-dimethyl-formamide for 24h; Ambient temperature;	100%
With 1H-imidazole 1.) THF, reflux, 5 min, 2.) THF, reflux, 24 h; Yield given. Multistep reaction;

: 544-62-7
batyl alcohol

: 75-36-5
acetyl chloride

: 21994-81-0
1-O-octadecyl-2,3-diacetylglycerol

Conditions

Conditions	Yield
at 140℃; for 0.0833333h; Inert atmosphere; Sealed tube;	93%

: 108-05-4
vinyl acetate

: 544-62-7
batyl alcohol

: 1-O-octadecyl-3-acetylglycerol

Conditions

Conditions	Yield
With immobilised Candida antarctica lipase In chloroform at 0 - 4℃; for 2h;	91%

: 108-05-4
vinyl acetate

: 544-62-7
batyl alcohol

: 21994-81-0
1-O-octadecyl-2,3-diacetylglycerol

Conditions

Conditions	Yield
With immobilised Candida antarctica lipase at 65℃; for 17h;	90%

: 51792-34-8
2,3-dimethoxythiophene

: 544-62-7
batyl alcohol

: 1409917-62-9
2-[(octadecyloxy)methyl]-2,3-dihydrothieno[3,4-b][1,4]dioxine

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene for 72h; Reflux;	88%

: 544-62-7
batyl alcohol

: 5146-30-5
10-phenyl-10-hydroxy-9-anthracenone

: 77588-21-7
1-Octadecyloxy-3-tritylonoxy-2-propanol

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In benzene for 22h; Heating;	67.5%

: 544-62-7
batyl alcohol

: (octadecyloxy)methyl formate

Conditions

Conditions	Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutylammomium bromide; 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 4h; Time; Inert atmosphere;	66%

: 544-62-7
batyl alcohol

: 98-59-9
p-toluenesulfonyl chloride

: 86541-07-3
2-hydroxy-3-(octadecyloxy)propyl p-toluenesulfonate

Conditions

Conditions	Yield
With pyridine In dichloromethane for 48h; Ambient temperature;	55%
With pyridine

: 544-62-7
batyl alcohol

: 25580-78-3
1-[(prop-2'-en-1'-yl)oxy]octadecane

Conditions

Conditions	Yield
With ammonium perrhenate; zinc In benzene at 150℃; for 24h; Inert atmosphere; Sealed tube;	47%
With ammonium perrhenate; benzyl alcohol In toluene at 150℃; for 24h; Sealed tube; regioselective reaction;	83 %Spectr.
With ammonium perrhenate; 2,4-dimethyl-3-pentanol In toluene at 140℃; for 24h; Sealed tube; regioselective reaction;	73 %Chromat.

: 112-16-3
n-dodecanoyl chloride

: 544-62-7
batyl alcohol

: 182277-36-7
1-O-octadecyl-3-O-lauroyl-rac-glycerol

Conditions

Conditions	Yield
With pyridine In chloroform for 1h; Ambient temperature;	41%

: 19172-47-5
Lawessons reagent

: 544-62-7
batyl alcohol

: 2-(4-Methoxy-phenyl)-4-octadecyloxymethyl-[1,3,2]dioxaphospholane 2-sulfide

Conditions

Conditions	Yield
In toluene at 100℃; for 3h;	37.85%

: 544-62-7
batyl alcohol

: 596-43-0
bromo-triphenyl-methane

: 118477-26-2
1-octadecyloxy-2,3-bis-trityloxy-propane

Conditions

Conditions	Yield
With pyridine
With pyridine

: 544-62-7
batyl alcohol

: 31081-59-1
1-octadecyl methanesulfonate

: 6297-03-6
19-oxaheptatriacontane

Conditions

Conditions	Yield
With potassium hydroxide In xylene Heating;

: 544-62-7
batyl alcohol

: 31081-59-1
1-octadecyl methanesulfonate

: 6076-42-2
1,2,3-tri(octadecyloxy)propane

Conditions

Conditions	Yield
With potassium hydroxide In xylene Heating;

: 544-62-7
batyl alcohol

: 31081-59-1
1-octadecyl methanesulfonate

: 18794-74-6
1,3-bis(octadecyloxy)-2-propanol

Conditions

Conditions	Yield
With potassium hydroxide In xylene Heating;

: 544-62-7
batyl alcohol

: 60956-72-1
octadecan-1-yloxyacetaldehyde

Conditions

Conditions	Yield
With sodium periodate In methanol
(i) aq. NaIO4, CHCl3, EtOH, (ii) aq. AcOH; Multistep reaction;
With sodium periodate In water; acetone for 1.5h; Ambient temperature;

: 544-62-7
batyl alcohol

: 96235-95-9
1-octadecyloxy-3-stearoyloxy-propan-2-ol

Conditions

Conditions	Yield
In pyridine; chloroform (monoacylation);

: 544-62-7
batyl alcohol

: 29909-05-5
1-O-Octadecyl-3-O-benzoyl-2-propanon

Conditions

Conditions	Yield
(i) (benzoylation), (ii) DCC, DMSO, CF3CO2H; Multistep reaction;

: 544-62-7
batyl alcohol

: 108-24-7
acetic anhydride

: 21994-81-0
1-O-octadecyl-2,3-diacetylglycerol

Batyl alcohol Chemical Properties

Molecular Structure of 3-Octadecoxypropane-1,2-diol (CAS NO.51-74-1):

IUPAC Name: 3-Octadecoxypropane-1,2-diol
Empirical Formula: C₂₁H₄₄O₃
Molecular Weight: 344.5723
H bond acceptors: 3
H bond donors: 2
Freely Rotating Bonds: 22
Polar Surface Area: 27.69Å²
Index of Refraction: 1.464
Molar Refractivity: 104.11 cm³
Molar Volume: 376.9 cm³
Surface Tension: 35.2 dyne/cm
Density: 0.914 g/cm³
Flash Point: 238.7 °C
Enthalpy of Vaporization: 84.6 kJ/mol
Boiling Point: 471.1 °C at 760 mmHg
Vapour Pressure: 7.44E-11 mmHg at 25°C
Classification Code: Drug / Therapeutic Agent
Apperance: white crystalline powder
InChI
InChI=1/C21H44O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-20-21(23)19-22/h21-23H,2-20H2,1H3
Smiles
C(CCCCCCCCCCCCCCC)CCOC[C@@H](CO)O

Batyl alcohol Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	750mg/kg (750mg/kg)		National Technical Information Service. Vol. AD691-490,
mouse	LD50	subcutaneous	> 3032mg/kg (3032mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: MUSCLE WEAKNESS	Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 470, 1948.

Batyl alcohol Consensus Reports

Reported in EPA TSCA Inventory.

Batyl alcohol Safety Profile

Moderately toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating vapors.

Batyl alcohol Specification

3-Octadecoxypropane-1,2-diol , with CAS number of 51-74-1, can be called 1,2-Propanediol, 3- (octadecyloxy)- ; 3-(Octadecyloxy)-1,2-propandiol ; 3-(Octadecyloxy)propane-1,2-diol ; Batylol ; (+)-Batylalcohol ; .alpha.-Octadecylether of glycerol . 3-Octadecoxypropane-1,2-diol (CAS NO.544-62-7) is one of the commonly used drugs promoted the proliferation of white blood cell proliferation.

Product Name

Batyl alcohol

Synthetic route

Batyl alcohol Chemical Properties

Batyl alcohol Toxicity Data With Reference

Batyl alcohol Consensus Reports

Batyl alcohol Safety Profile

Batyl alcohol Specification

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