IUPAC Name: 1-(4-Aminophenyl)sulfonyl-3-butylurea
The molecular formula of Carbutamide (CAS NO.339-43-5) is C11H17N3O3S.
e molecular weight of Carbutamide (CAS NO.339-43-5) is 271.336.
Synonyms of Carbutamide (CAS NO.339-43-5): Benzenesulfonamide, 4-amino-N-((butylamino)carbonyl)- ; 1-Butyl-3-sulfanilylurea ; 1-[(4-aminobenzene)sulfonyl]-3-butylurea ; 4-Amino-N-((butylamino)carbonyl)benzenesulfonamide
Index of Refraction: 1.564
EINECS: 206-424-4
Density: 1.266 g/ml
Carbutamide (CAS NO.339-43-5) is used as hypoglycemic.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 250mg/kg (250mg/kg) | National Technical Information Service. Vol. AD691-490, | |
mouse | LD50 | intravenous | 1920mg/kg (1920mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Diabetes. Vol. 6, Pg. 2, 1957. |
mouse | LD50 | oral | 2800mg/kg (2800mg/kg) | Farmakologiya i Toksikologiya Vol. 25, Pg. 93, 1962. | |
mouse | LD50 | subcutaneous | 2640mg/kg (2640mg/kg) | Diabetes. Vol. 6, Pg. 2, 1957. | |
rat | LD50 | intravenous | 980mg/kg (980mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Diabetes. Vol. 6, Pg. 2, 1957. |
rat | LD50 | oral | 4400mg/kg (4400mg/kg) | French Demande Patent Document. Vol. #2390165, |
Reported in EPA TSCA Inventory.
A poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.
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