Bis(2-chloroisopropyl) ether supplier

Name
BIS(2-CHLOROISOPROPYL)ETHER
EINECS 203-598-3
CAS No. 108-60-1
Article Data10
CAS DataBase
Density 1.086 g/cm³
Solubility Solubility in water, g/100 ml at 20ºC: 0.2, poor
Melting Point -97 to -102ºC
Formula C6H12 Cl2 O
Boiling Point 187 °C at 760 mmHg
Molecular Weight 171.067
Flash Point 36.4 °C
Transport Information
Appearance COLOURLESS TO BROWN, OILY LIQUID
Safety Poison by ingestion. Moderately toxic by skin contact and inhalation. An eye irritant. Questionable carcinogen. Mutation data reported. A corrosive material. Moderate fire hazard when exposed to heat, flame, or powerful oxidizers. Incompatible with oxidizing materials. To fight fire, use water to blanket fire; foam, CO₂, dry chemical. When heated to decomposition it emits highly toxic fumes of Cl⁻. See also ETHERS.
Risk Codes 22-36/37/38-39/23/24/25-23/24/25-11
Molecular Structure
Hazard Symbols Toxic by ingestion and inhalation, strong irritant.
Synonyms Ether,bis(2-chloro-1-methylethyl) (6CI,7CI,8CI);2,2'-Dichlorodiisopropyl ether;2,2'-Oxybis(1-chloropropane);Bis(1-chloro-2-propyl) ether;Bis(2-chloro-1-methylethyl) ether;DCIP;DCIP (nematocide);NSC 2849;b,b'-Dichlorodiisopropyl ether;
PSA 9.23000
LogP 2.95280

Synthetic route

: 187737-37-7
propene

: 108-60-1
bis(1-chloro-2-propyl) ether

Conditions

Conditions	Yield
With metal salt; water; chlorine

: 77-78-1
dimethyl sulfate

: 127-00-4
1-Chloro-2-propanol

A: 5390-72-7
2-methoxy-1-chloropropane

B: 108-60-1
bis(1-chloro-2-propyl) ether

...Expand

: 127-00-4
1-Chloro-2-propanol

: 108-60-1
bis(1-chloro-2-propyl) ether

Conditions

Conditions	Yield
With sulfuric acid

: 187737-37-7
propene

: 75-56-9, 16033-71-9
methyloxirane

: 108-60-1
bis(1-chloro-2-propyl) ether

Conditions

Conditions	Yield
With water; chlorine
With water; chlorine

: 187737-37-7
propene

A: 26198-63-0, 78-87-5
1,2-Dichloropropane

B: 629-36-7
bis(3-chloropropyl)ether

C: 108-60-1
bis(1-chloro-2-propyl) ether

D: 127-00-4
1-Chloro-2-propanol

Conditions

Conditions	Yield
With hypochloric acid; chlorine In butanone at 20℃; for 0.00833333h; in a rotor-pulsation apparatus; Title compound not separated from byproducts;	A 15.8 % Spectr. B n/a C n/a D 68.6 % Spectr.
With hypochloric acid; chlorine In butanone at 20℃; for 0.00833333h; Product distribution; Mechanism; yield of products at different temperatures and in different solvents, in a rotor-pulsation apparatus;	A 15.8 % Spectr. B n/a C n/a D 68.6 % Spectr.

...Expand

: 187737-37-7
propene

: 127-00-4
1-Chloro-2-propanol

A: 26198-63-0, 78-87-5
1,2-Dichloropropane

B: 108-60-1
bis(1-chloro-2-propyl) ether

C: 83270-31-9
1-chloro-2-propyl 2-chloro-1-propyl ether

Conditions

Conditions	Yield
With chlorine In dichloromethane at -20℃; Yield given. Yields of byproduct given;

...Expand

: 187737-37-7
propene

: 75-56-9, 16033-71-9
methyloxirane

A: 26198-63-0, 78-87-5
1,2-Dichloropropane

B: 108-60-1
bis(1-chloro-2-propyl) ether

C: 54460-96-7
bis-(2-chloro-propyl) ether

D: 83270-31-9
1-chloro-2-propyl 2-chloro-1-propyl ether

Conditions

Conditions	Yield
With chlorine In dichloromethane at -20℃; Yield given. Further byproducts given. Yields of byproduct given;

...Expand

: 187737-37-7
propene

: 7732-18-5
water

: 7782-50-5
chlorine

: 108-60-1
bis(1-chloro-2-propyl) ether

Conditions

Conditions	Yield
durch Propylenoxyd;

...Expand

: 187737-37-7
propene

: 7732-18-5
water

: 7782-50-5
chlorine

A: 26198-63-0, 78-87-5
1,2-Dichloropropane

B: 108-60-1
bis(1-chloro-2-propyl) ether

C: 78-95-5
chloroacetone

D: 127-00-4
1-Chloro-2-propanol

Conditions

Conditions	Yield
at 34 - 43℃;

...Expand

: 187737-37-7
propene

: 7732-18-5
water

: 7782-50-5
chlorine

A: 26198-63-0, 78-87-5
1,2-Dichloropropane

B: 108-60-1
bis(1-chloro-2-propyl) ether

C CH3+CH(OH)+CH2Cl: CH3+CH(OH)+CH2Cl

D CH3+CHCl+CH2+OH: CH3+CHCl+CH2+OH

Conditions

Conditions	Yield
at 60℃;
at 60℃;

...Expand

: 108-60-1
bis(1-chloro-2-propyl) ether

: 22487-02-1
sodium n-hexylmercaptide

: 9,11-Dimethyl-10-oxa-7,13-dithia-nonadecan

Conditions

Conditions	Yield
In pentan-1-ol for 8h; Heating;	53%

: 110-91-8
morpholine

: 108-60-1
bis(1-chloro-2-propyl) ether

: 2,6-dimethyl-4-(2-vinyloxy-ethyl)-morpholine

Conditions

Conditions	Yield
With sodium hydroxide Erwaermen des Reaktionsprodukts mit wss. NaOH;
With sodium hydroxide Erwaermen des Reaktionsprodukts mit aethanol. NaOH;

: 124-22-1
n-Dodecylamine

: 108-60-1
bis(1-chloro-2-propyl) ether

: 1704-28-5
aldimorph

Conditions

Conditions	Yield
With sodium carbonate; butan-1-ol

: 108-60-1
bis(1-chloro-2-propyl) ether

: 78-96-6, 1674-56-2
3-amino-2-propanol

: 4-(2-methoxy-propyl)-2,6-dimethyl-morpholine

Conditions

Conditions	Yield
Erwaermen des Reaktionsprodukts mit Dimethylsulfat und wss. NaOH;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 3007-31-6
N,N-didodecylamine

: 4,4-didodecyl-2,6-dimethyl-morpholinium; chloride

Conditions

Conditions	Yield
With sodium carbonate; butan-1-ol

: 108-60-1
bis(1-chloro-2-propyl) ether

: 112-99-2
Dioctadecylamine

: 121446-92-2
2,6-dimethyl-4,4-dioctadecyl-morpholinium; chloride

Conditions

Conditions	Yield
With sodium carbonate; butan-1-ol

: 108-60-1
bis(1-chloro-2-propyl) ether

: 127-08-2
potassium acetate

: 20726-65-2
bis-(β-acetoxy-isopropyl)-ether

Conditions

Conditions	Yield
With acetic acid

: 108-60-1
bis(1-chloro-2-propyl) ether

: 71172-25-3
2,6-dimethyl-[1,4]oxathiane

Conditions

Conditions	Yield
With sodium sulfide; ethanol

: 108-60-1
bis(1-chloro-2-propyl) ether

: 141-91-3
2,6-dimethyl morpholine

Conditions

Conditions	Yield
With ammonium hydroxide at 120℃;
With ammonium hydroxide at 120℃;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 26103-10-6
(β-chloro-isopropyl)-isopropenyl ether

Conditions

Conditions	Yield
With sodium hydroxide; triethanolamine at 240℃;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 4188-73-2
bisisopropenyl ether

Conditions

Conditions	Yield
With sodium hydroxide; triethanolamine at 240℃; beim Erwaermen des Reaktionsprodukts mit Natriumhydroxid und Tris-<2-hydroxy-aethyl>-amin;
With potassium hydroxide

: 108-60-1
bis(1-chloro-2-propyl) ether

: 89-40-7
4-nitrophthalimide

: 5,5'-dinitro-2,2'-(2,4-dimethyl-3-oxa-pentanediyl)-bis-isoindoline-1,3-dione

Conditions

Conditions	Yield
With potassium carbonate; N,N-dimethyl-formamide; potassium iodide at 135 - 140℃;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 141-43-5
ethanolamine

: 73813-49-7
4-(2-hydroxyethyl)-2,6-dimethylmorpholine

Conditions

Conditions	Yield
With potassium carbonate at 150℃;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 108-98-5
thiophenol

: 2-(β-phenylsulfanyl-isopropoxy)-propane-1-thiol

Conditions

Conditions	Yield
With ethanol; sodium ethanolate Erhitzen des Reaktionsprodukts mit KHS in Methanol auf 150-160grad;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 140-66-9
tert-octylphenol

: 857578-97-3
2-(β-chloro-isopropoxy)-1-[4-(1,1,3,3-tetramethyl-butyl)-phenoxy]-propane

Conditions

Conditions	Yield
With sodium hydroxide at 110℃;
With sodium hydroxide at 110℃;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 124-30-1
1-aminooctadecane

: 1541-93-1
2,6-dimethyl-4-octadecyl-morpholine

Conditions

Conditions	Yield
With sodium carbonate; butan-1-ol

: 57-55-6
propylene glycol

: 108-60-1
bis(1-chloro-2-propyl) ether

: 72562-47-1
1,1'-(2,4-dimethyl-3-oxa-pentane-1,5-diyldioxy)-bis-propan-2-ol

Conditions

Conditions	Yield
(i) Na, (ii) /BRN= 1735833/; Multistep reaction;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 107-21-1
ethylene glycol

: 72562-46-0
2,2'-(2,4-dimethyl-3-oxa-pentane-1,5-diyldioxy)-bis-ethanol

Conditions

Conditions	Yield
(i) Na, (ii) /BRN= 1735833/; Multistep reaction;

: 108-60-1
bis(1-chloro-2-propyl) ether

: 75-36-5
acetyl chloride

: 623-60-9
1-chloro-2-acetoxypropane

Conditions

Conditions	Yield
With zinc(II) chloride

: 108-60-1
bis(1-chloro-2-propyl) ether

: 201230-82-2
carbon monoxide

: 71-43-2
benzene

: 1005420-27-8, 10474-32-5, 887255-49-4
(±)-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
With aluminium trichloride at 22 - 24℃; for 2.5h;

...Expand

: 23116-94-1
bis(2-hydroxyphenoxyethyl)ether

: 108-60-1
bis(1-chloro-2-propyl) ether

: 6,8-dimethyldibenzo-18-crown-6

Conditions

Conditions	Yield
With potassium hydroxide; butan-1-ol

: 110-91-8
morpholine

: 108-60-1
bis(1-chloro-2-propyl) ether

: furan-2,3,5(4H)-trione pyridine (1:1)

2.6.2'.6'-tetramethyl-dimorphousolynium chloride: 2.6.2'.6'-tetramethyl-dimorphousolynium chloride

Conditions

Conditions	Yield
at 100℃;

...Expand

Bis(2-chloroisopropyl) ether Chemical Properties

Bis(2-chloroisopropyl) ether ,its CAS register number is 108-60-1,it's called for DCIP ; Dichloroisopropyl ether ; Bis-(2-chloro-1-methylethyl)ether ; (2-Chloro-1-methylethyl) ether ; (2-Chloro-1-methylethyl)ether ; 1-Chloro-2-(2-chloro-1-methylethoxy)propane ; 2,2’-Dichlorodiisopropylether ; Nemamol ; Isopropylchlorex ; Pichloram ,and so on. Bis(2-chloroisopropyl) ether (CAS No.108-60-1 ) is colorless to light brown liquid.

IUPAC Name: 1-Chloro-2-(1-chloropropan-2-yloxy)propane
CAS: 108-60-1
Molecular Formula: C₆H₁₂Cl₂O
Molecular Weight: 171.06
Molecular structure:
EINECS: 203-598-3
Storage temp.: 0-6°C
ACD/LogD (pH 5.5): 1.88
ACD/LogD (pH 7.4): 1.88
ACD/BCF (pH 5.5): 15.84
ACD/BCF (pH 7.4): 15.84
ACD/KOC (pH 5.5): 251.45
ACD/KOC (pH 7.4): 251.45
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 4
Index of Refraction: 1.436
Molar Refractivity: 41.2 cm³
Molar Volume: 157.4 cm³
Polarizability: 16.33 10^-24cm³
Surface Tension: 27.9 dyne/cm
Density: 1.086 g/cm³
Flash Point: 36.4 °C
Enthalpy of Vaporization: 40.59 kJ/mol
Boiling Point: 187 °C at 760 mmHg
Vapour Pressure: 0.887 mmHg at 25°C

Bis(2-chloroisopropyl) ether Uses

Bis(2-chloroisopropyl) ether (CAS No.108-60-1 ) is commonly used as the standard agent for analysis.

Bis(2-chloroisopropyl) ether Toxicity Data With Reference

1.	eye-rbt 500 mg open	AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
2.	mmo-sat 1 mL/plate/3H	DHEFDK HEW Publication (FDA. United States). (Washington, DC) 19??-1979(?). FDA-78-1046 ,1978.
3.	mma-sat 333 µg/plate	ENMUDM Environmental Mutagenesis. 8 (Suppl 7)(1986),1.
4.	orl-rat LD50:240 mg/kg	AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.
5.	skn-rat LD50:>2 g/kg	PEMNDP Pesticide Manual. 9 (1991),83.
6.	orl-mus LD50:503 mg/kg	FMCHA2 Farm Chemicals Handbook .(Meister Publishing, 37841 Euclid Ave.,Willoughy, OH.: 44094)1991,C216.
7.	ihl-rat LCLo:700 ppm/5H	BJIMAG British Journal of Industrial Medicine. 27 (1970),1.
8.	skn-rbt LD50:3000 mg/kg	AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. 4 (1951),119.

Bis(2-chloroisopropyl) ether Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 41 (1986),p. 149.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (gavage); No Evidence: rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-191 ,1979. . Community Right-To-Know List. Reported in EPA TSCA Inventory.

Bis(2-chloroisopropyl) ether Safety Profile

Poison by ingestion. Moderately toxic by skin contact and inhalation. An eye irritant. Questionable carcinogen. Mutation data reported. A corrosive material. Moderate fire hazard when exposed to heat, flame, or powerful oxidizers. Incompatible with oxidizing materials. To fight fire, use water to blanket fire; foam, CO₂, dry chemical. When heated to decomposition it emits highly toxic fumes of Cl⁻.

Hazard Codes: Xn,T,F
Risk Statements: 22-36/37/38-39/23/24/25-23/24/25-11 (R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin. R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. R11:Highly flammable.)
Safety Statements: 26-45-36/37-16-7 (S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37:Wear suitable protective clothing and gloves. S16:Keep away from sources of ignition. S7:Keep container tightly closed.)
RIDADR: 2490
RTECS: KN1750000
HazardClass: 6.1(a)
PackingGroup: II

Bis(2-chloroisopropyl) ether Standards and Recommendations

DOT Classification: 6.1; Label: Poison

Bis(2-chloroisopropyl) ether Specification

Removal in wastewater treatment of Bis(2-chloroisopropyl) ether (CAS No.108-60-1 ) can be stated as follows:
Total removal:8.29 percent
Total biodegradation:0.10 percent
Total sludge adsorption:2.83 percent
Total to Air:5.37 percent
(using 10000 hr Bio P,A,S)

Product Name

BIS(2-CHLOROISOPROPYL)ETHER

Synthetic route

Bis(2-chloroisopropyl) ether Chemical Properties

Bis(2-chloroisopropyl) ether Uses

Bis(2-chloroisopropyl) ether Toxicity Data With Reference

Bis(2-chloroisopropyl) ether Consensus Reports

Bis(2-chloroisopropyl) ether Safety Profile

Bis(2-chloroisopropyl) ether Standards and Recommendations

Bis(2-chloroisopropyl) ether Specification

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