Budipine supplier | CasNO.57982-78-2

Name
BUDIPINE
EINECS
CAS No. 57982-78-2
Article Data1
CAS DataBase
Density 1.009g/cm³
Solubility
Melting Point 108.5°C
Formula C21H27 N
Boiling Point 387.6°Cat760mmHg
Molecular Weight 293.452
Flash Point 168.7°C
Transport Information
Appearance
Safety Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1-tert-Butyl-4,4-diphenylpiperidine;Budipine
PSA 3.24000
LogP 4.80490

Synthetic route

: 1465-76-5
1-tert-butyl-piperidin-4-one

: 71-43-2
benzene

: 57982-78-2
budipine

Conditions

Conditions	Yield
With aluminium trichloride at 60℃; for 2h; Yield given;

: 81831-81-4
(1-tert-butyl-4-hydroxy-4-phenyl-piperidin-3-yl)-phenyl-methanone

: 71-43-2
benzene

A: 57982-78-2
budipine

B: 1,4-Bis<1-tert-butyl-4-phenyl-piperidyl-(4)>-benzol

Conditions

Conditions	Yield
With aluminium trichloride 1.) 45 deg C, 30 min, 2.) 50-55 deg C, 1 h; Yield given;

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Budipine Chemical Properties

Chemistry informtion about Budipine (CAS NO.57982-78-2) is:
IUPAC Name: 1-Tert-Butyl-4,4-Diphenylpiperidine
Synonyms: Budipine ; 1-(1,1-Dimethylethyl)-4,4-Diphenyl-Piperidin ; 1-(1,1-Dimethylethyl)-4,4-Diphenylpiperidine ; Budipin ; 1-Tert-Butyl-4,4-Diphenyl-Piperidine ; Budipine(Forr&Donly) ; 4,4-Diphenyl-1-Tert-Butyl-Piperidine
MF: C₂₁H₂₇N
MW: 293.45
EINECS: 261-062-4
Density: 1.009 g/cm³
Flash Point: 168.7 °C
Boiling Point: 387.6 °C at 760 mmHg
Vapour Pressure: 3.25E-06 mmHg at 25°C
Enthalpy of Vaporization: 63.67 kJ/mol
Following is the molecular structure of Budipine (CAS NO.57982-78-2) is:

Budipine Uses

Budipine (CAS NO.57982-78-2) is believed to be a NMDA receptor antagonist, and to promote the synthesis of dopamine. Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment.

Budipine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intravenous	33mg/kg (33mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.
mouse	LD50	oral	120mg/kg (120mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.
rat	LD50	intravenous	28mg/kg (28mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.
rat	LD50	oral	165mg/kg (165mg/kg)	Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 85, 1982.

Budipine Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x.

Budipine Specification

Budipine (CAS NO.57982-78-2) is a dopaminergic agent. Its mechanism is not well characterized.

Product Name

BUDIPINE