-
Name
CYCLOPENTOLATE HYDROCHLORIDE
- EINECS 227-521-8
- CAS No. 5870-29-1
- Article Data1
- CAS DataBase
- Density g/cm3
- Solubility
- Melting Point 137-141°
- Formula C17H25 N O3 . Cl H
- Boiling Point 409.7°Cat760mmHg
- Molecular Weight 327.851
- Flash Point 201.5°C
- Transport Information
- Appearance
- Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: convulsions, distorted perceptions, hallucinations, toxic psychosis. When heated to decomposition it emits toxic fumes of NOx and HCl. See also ESTERS.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Benzeneaceticacid, a-(1-hydroxycyclopentyl)-,2-(dimethylamino)ethyl ester, hydrochloride (9CI); Cyclopentaneacetic acid,1-hydroxy-a-phenyl-, 2-(dimethylamino)ethylester hydrochloride (8CI); (?à)-Cyclopentolate-hydrochloride; 2-(Dimethylamino)ethyl 1-hydroxy-a-phenylcyclopentaneacetatehydrochloride; Ak-Pentolate; Alnide; Cyclopentolate hydrochloride; Cyplegin;Mydplegic; Mydrilate; Zyklolat; b-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate hydrochloride
- PSA 49.77000
- LogP 2.98210
CYCLOPENTOLATE HYDROCHLORIDE Chemical Properties
Product Name: Cyclopentolate hydrochloride (CAS NO.5870-29-1)
Molecular Formula: C17H26ClNO3
Molecular Weight: 327.85g/mol
Mol File: 5870-29-1.mol
Einecs: 227-521-8
Boiling point: 409.7 °C at 760 mmHg
Storage Temperature: −20°C
Flash Point: 201.5 °C
Enthalpy of Vaporization: 69.79 kJ/mol
Vapour Pressure: 1.91E-07 mmHg at 25°C
XLogP3-AA:
H-Bond Donor: 2
H-Bond Acceptor: 4
CYCLOPENTOLATE HYDROCHLORIDE Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| child | TDLo | ocular | 50ug/kg/I (0.05mg/kg) | BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: TOXIC PSYCHOSIS | American Journal of Ophthalmology. Vol. 105, Pg. 91, 1988. |
| child | TDLo | subcutaneous | 40ug/kg (0.04mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archives of Ophthalmology Vol. 87, Pg. 634, 1972. |
| mouse | LD50 | intraperitoneal | 314mg/kg (314mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 106, Pg. 141, 1952. | |
| mouse | LD50 | intravenous | 63mg/kg (63mg/kg) | Drugs in Japan Vol. -, Pg. 516, 1995. | |
| mouse | LD50 | oral | 960mg/kg (960mg/kg) | Drugs in Japan Vol. 6, Pg. 314, 1982. | |
| mouse | LD50 | subcutaneous | 292mg/kg (292mg/kg) | Drugs in Japan Vol. -, Pg. 444, 1990. | |
| rat | LD50 | oral | > 4gm/kg (4000mg/kg) | Drugs in Japan Vol. 6, Pg. 314, 1982. | |
| rat | LD50 | subcutaneous | 2235mg/kg (2235mg/kg) | Drugs in Japan Vol. -, Pg. 444, 1990. |
CYCLOPENTOLATE HYDROCHLORIDE Safety Profile
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: convulsions, distorted perceptions, hallucinations, toxic psychosis. When heated to decomposition it emits toxic fumes of NOx and HCl. See also ESTERS.
CYCLOPENTOLATE HYDROCHLORIDE Specification
Cyclopentolate hydrochloride ,its CAS NO. is 5870-29-1,the synonyms is Labotest-bb lt00244824 ; 2-Dimethylaminoethyl 1-hydroxy-alpha-phenylcyclopentaneacetate hydrochloride ; 2-(Dimethylamino)ethyl1-hydroxy-alpha-phenylcyclopentaneacetatehydrochlorid ; Alpha-(1-hydroxycyclopentyl)-benzeneaceticaci2-(dimethylamino)ethylest ; Beta-dimethylaminoethyl(1-hydroxycyclopentyl)phenylacetatehydrochloride ; Cyclogyl ; Cyclopentaneaceticacid,1-hydroxy-alpha-phenyl-,2-(dimethylamino)ethylester .
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