Product Name

Stability

    Stable. Combustible. Incompatible with acids, alkalies,strong oxidizing agents.

Toxicology

    Harmful if swallowed or inhaled.

    Toxicity data
    (T

  • Melting Point 118 C
  • Formula C7H13 Br N2 O2
  • Boiling Point
  • Molecular Weight 237.096
  • Flash Point
  • Transport Information
  • Appearance white crystalline powder
  • Safety Poison by ingestion, subcutaneous, and possibly other routes. Moderately toxic via intravenous and intraperitoneal routes. Mutation data reported. A sedative, hypnotic, and central nervous system depressant. When heated to decomposition it emits very toxic fumes of NOx and Br−.
  • Risk Codes
  • Molecular Structure Molecular Structure of 77-65-6 ((2-BROMO-2-ETHYLBUTYRYL)UREA)
  • Hazard Symbols
  • Synonyms Carbromal(6CI); Urea, (2-bromo-2-ethylbutyryl)- (8CI); (a-Bromo-a-ethylbutyryl)carbamide; (a-Bromo-a-ethylbutyryl)urea;2-Bromo-2-ethylbutyrylurea; Adalin; Adisomnol; Bromacetocarbamide; Bromadal;Bromdiethylacetylurea; Bromodiethylacetylcarbamide; Diacid; Dormiturin; Hoggar;Karbromal; Kartryl; NSC 49191; NSC 9916; Nenesin; Nyctal; Parkosed; Pelidorm;Planadalin; Tildin; Uradal; a-Ethyl-a-bromobutyrylurea
  • PSA 72.19000
  • LogP 2.22620

Carbromal Chemical Properties

Empirical Formula: C7H13BrN2O2
Molecular Weight: 237.0943 g/mol
EINECS: 201-046-6
Index of Refraction: 1.513
Density: 1.445 g/cm3
Solubility: Insoluble in water
Appearance: Odorless tasteless white crystalline powder
Structure of Carbromal (CAS NO.77-65-6):
                    
IUPAC Name of Carbromal (CAS NO.77-65-6): 2-Bromo-N-carbamoyl-2-ethylbutanamide

Carbromal Toxicity Data With Reference

1.    

cyt-smc 10 mmol/tube

     HEREAY    Hereditas. 33 (1947),457.
2.    

ipr-rat LD50:427 mg/kg

     ITMZBJ    Intensivmedizin. 17 (1980),305.
3.    

ivn-rat LD50:427 mg/kg

     ARTODN    Archives of Toxicology. 40 (1978),211.
4.    

unr-rat LDLo:350 mg/kg

     JPHAA3    Journal of the American Pharmaceutical Association. 23 (1934),788.
5.    

orl-mus LD50:464 mg/kg

     NCILB*    Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to the National Cancer Institute by Litton Bionetics, Inc. (Bethesda, MD) NIH-NCI-E-C-72-3252 (1973).
6.    

orl-dog LD50:450 mg/kg

     MEIEDD    Merck Index. 10 (1983),254.
7.    

scu-dog LDLo:300 mg/kg

     HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1292.
8.    

orl-cat LDLo:350 mg/kg

     HBAMAK    “Abdernalden’s Handbuch der Biologischen Arbeitsmethoden.“ 4 (1935),1293.
9.    

orl-rbt LDLo:600 mg/kg

     SAPHAO    Skandinavisches Archiv fuer Physiologic. 28 (1913),193.
10.    

scu-frg LDLo:1667 mg/kg

     HBAMAK    “Abdernalden&rsqu

Carbromal Consensus Reports

NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-173 (1979). . Reported in EPA TSCA Inventory.

Carbromal Safety Profile

Poison by ingestion, subcutaneous, and possibly other routes. Moderately toxic via intravenous and intraperitoneal routes. Mutation data reported. A sedative, hypnotic, and central nervous system depressant. When heated to decomposition it emits very toxic fumes of NOx and Br−.

Carbromal Specification

 Carbromal ,its cas register number is 77-65-6. It also can be called 2-Bromo-2-ethylbutyrylurea ; Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl- ; and Urea, (2-bromo-2-ethylbutyryl)- . Carbromal (CAS NO.77-65-6) may be sensitive to prolonged exposure to air and light, and is incompatible with acids and alkalis.

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