Product Name

  • Name

    Cefazedone sodium salt

  • EINECS 264-293-9
  • CAS No. 63521-15-3
  • Article Data8
  • CAS DataBase
  • Density 1.78g/cm3
  • Solubility
  • Melting Point
  • Formula C18H15 Cl2 N5 O5 S3 . Na
  • Boiling Point
  • Molecular Weight 570.433
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. Used as an antibacterial agent. When heated to decomposition, it emits very toxic fumes of Cl, NOx, Na2O, and SOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 63521-15-3 (Cefazedone sodium salt)
  • Hazard Symbols
  • Synonyms 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(3,5-dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7R)- (9CI); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(3,5-dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-,monosodium salt, (6R-trans)-; Cefazedone sodium; Cefazedone sodium salt; EMD30087; NSC 304118; Refosporin
  • PSA 216.16000
  • LogP 0.84000

Cefazedone sodium salt Chemical Properties

IUPAC Name: Sodium (6R,7R)-7-[[2-(3,5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Synonyms: Sodium (6R-trans)-7-[[(3,5-dichloro-4-oxo-1(4H)-pyridyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;Cefazedone, sodium salt ; Sodium (6R,7R)-7-[[(3,5-dichloro-4-oxo-1(4H)-pyridyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ; (6R,7R)-7-[[2-(3,5-Dichloro-4-oxopyridin-1(4H)-yl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
Molecular Structure of Refosporen (CAS NO.63521-15-3) :
Molecular Formula of Refosporen (CAS NO.63521-15-3) : C18H14Cl2N5NaO5S3
Molecular Weight of Refosporen (CAS NO.63521-15-3) : 570.42
CAS NO: 63521-15-3
EINECS: 264-293-9

Cefazedone sodium salt Uses

 Refosporen (CAS NO.63521-15-3) has a significant effect of broad-spectrum antibacterial.

Cefazedone sodium salt Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous 3gm/kg (3000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.
mouse LD50 intramuscular > 10gm/kg (10000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.
mouse LD50 intravenous 6800mg/kg (6800mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.
rabbit LD50 intravenous 3200mg/kg (3200mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.
rat LD50 intramuscular > 10gm/kg (10000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.
rat LD50 intravenous 4225mg/kg (4225mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979.

 

Cefazedone sodium salt Safety Profile

Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. Used as an antibacterial agent. When heated to decomposition, it emits very toxic fumes of Cl, NOx, Na2O, and SOx.

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