-
Name
Cefradine
- EINECS 254-137-8
- CAS No. 38821-53-3
- Article Data12
- CAS DataBase
- Density 1.47 g/cm3
- Solubility Soluble in water
- Melting Point 140-142 °C
- Formula C16H19N3O4S
- Boiling Point 693.1 °C at 760 mmHg
- Molecular Weight 349.411
- Flash Point 373 °C
- Transport Information
- Appearance Solid
- Safety 26-36
- Risk Codes 36/37/38-42/43-20/21/22
-
Molecular Structure
-
Hazard Symbols
Xn, 
Xi
- Synonyms 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-(9CI);7-[D-a-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranicacid;Anspor;Cefradex;Cefradin;Cefradine;Cefrag;Cefro;Celex;Cephradin;Cephradine;Cesporan;Dimacef;Easkacef;Ecosporina;Eskacef;Lenzacef;Lisacef;Megacef;SQ 11436;Samedrin;Sefril;Velocef;Velosef;
- PSA 138.03000
- LogP 1.37770
Cefradine Chemical Properties
Product Name: (6R-(6alpha,7))-((Amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (6r-(6alpha,7))-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;CEPHRADINE;CEPHRADINE HYDRATE;CEFRADIN;CEFRADINE;(6r-(6-alpha,7-beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-oxo;(6r-6alpha,7beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-ox;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((amino-1,4-cyclohexad
Product Categories: Drug bulk
The Molecular formula of Sefril (CAS NO.38821-53-3): C16H21N3O5S
The Molecular Weight of Sefril (CAS NO.38821-53-3): 367.42 g/mol
Molecular Structure of Sefril (CAS NO.38821-53-3): 
EINECS: 254-137-8
Melting point: 140-142 deg C
storage temp.: Store at 0-5°C
Appearance: Solid
Density: 1.47 g/cm3
Flash Point: 373 °C
Index of Refraction: 1.683
Surface Tension: 74.6 dyne/cm
Enthalpy of Vaporization: 110.65 kJ/mol
Boiling Point: 693.1 °C at 760 mmHg
Vapour Pressure of Sefril (CAS NO.38821-53-3): 4.85E-21 mmHg at 25 °C
Cefradine Toxicity Data With Reference
| 1. | orl-wmn TDLo:5 mg/kg:SKN | CUTIBC CUTIS; Cutaneous Medicine for the Practitioner. 38 (1986),58. | ||
| 2. | orl-mus LD50:3549 mg/kg | NKRZAZ Chemotherapy (Tokyo). 23 (1975),37. | ||
| 3. | ipr-mus LD50:597 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680. | ||
| 4. | scu-mus LD50:2890 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680. | ||
| 5. | ivn-mus LD50:3539 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680. |
Cefradine Safety Profile
Moderately toxic by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: dermatitis. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
The Hazard Codes of Sefril (CAS NO.38821-53-3):
Xi,
Xn
The Risk Statements information of SEFRIL(38821-53-3): 20/21/22-36/37/38-42/43
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R42/43:May cause sensitization by inhalation and skin contact.
The Safety Statements information of Sefril (CAS NO.38821-53-3): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
RTECS XI0336000
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