Product Name

  • Name

    2-Pyridinemethanamine,N-phenyl-N-[2-(1-piperidinyl)ethyl]-, hydrochloride (1:1)

  • EINECS
  • CAS No. 24699-40-9
  • Density
  • Solubility
  • Melting Point 183-185°
  • Formula C19H25 N3 . Cl H
  • Boiling Point
  • Molecular Weight 331.93
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 24699-40-9 (2-Pyridinemethanamine,N-phenyl-N-[2-(1-piperidinyl)ethyl]-, hydrochloride (1:1))
  • Hazard Symbols
  • Synonyms 2-Pyridinemethanamine,N-phenyl-N-[2-(1-piperidinyl)ethyl]-, monohydrochloride (9CI); Piperidine,1-[2-[N-(2-pyridylmethyl)anilino]ethyl]-, monohydrochloride (8CI); Coben;N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride; Picoperidaminehydrochloride; Picoperine hydrochloride
  • PSA 19.37000
  • LogP 4.31400

Coben Chemical Properties

 
Product Name: Coben
Molecular Formula: C19H25N3
Molecular Weight: 295.4219 g/mol
Mol File: 24699-40-9.mol 
Index of Refraction: 1.596
Molar Refractivity: 92.41 cm3
Molar Volume: 271.3 cm3 
Surface Tension: 48.6 dyne/cm
Boiling point: 448.5 °C at 760 mmHg
Flash Point: 225.1 °C
Density: 1.088 g/cm3
Surface Tension: 48.6 dyne/cm
Enthalpy of Vaporization: 70.71 kJ/mol
Vapour Pressure: 3.08E-08 mmHg at 25 °C

Coben Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 25mg/kg (25mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969.
dog LDLo oral 100mg/kg (100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1916, 1969.
mouse LD50 intraperitoneal 55500ug/kg (55.5mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.
mouse LD50 intravenous 10mg/kg (10mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.
mouse LD50 oral 195mg/kg (195mg/kg)   Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 29, Pg. 310, 1970.
mouse LD50 subcutaneous 142mg/kg (142mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.
rat LD50 intraperitoneal 69mg/kg (69mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.
rat LD50 intravenous 11500ug/kg (11.5mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.
rat LD50 oral 740mg/kg (740mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.
rat LD50 subcutaneous 480mg/kg (480mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Kiso to Rinsho. Clinical Report. Vol. 4, Pg. 403, 1970.

Coben Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx and HCl.

Coben Specification

 Coben ,its CAS NO. is 24699-40-9,the synonyms is -(2-(N-(2-Pyridylmethyl)anilino)ethyl)piperidine hydrochloride ; 1-(2-(Phenyl(2-pyridylmethyl)amino)ethyl)piperidine hydrochloride ; 2-Pyridinemethanamine, N-phenyl-N-(2-(1-piperidinyl)ethyl)-, monohydrochloride ; N-(2-Picolyl)-N-phenyl-N-(2-piperidinoethyl)amine hydrochloride ; N-(2-Piperidinoethyl)-N-(2-pyridylmethyl)aniline hydrochloride ; N-(2-Pyridylmethyl)-N-phenyl-N-2-(piperidinoethyl)amine hydrochloride ; N-Phenyl-N-(2-pyridylmethyl)-2-piperidinoethylamine hydrochloride ; Picoperidamine hydrochloride ; Picoperine HCl ; Picoperine hydrochloride ; Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, monohydrochloride ; TAT-3 hydrochloride ; Piperidine, 1-(2-(N-(2-pyridylmethyl)anilino)ethyl)-, hydrochloride .

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