1. Introduction of ConjugatedEstrogens
ConjugatedEstrogens is a dark yellow to orange powder. ConjugatedEstrogens belongs to the product categories which is Steroids. Besides, the Classification Code of this chemical is Drug / Therapeutic Agent; Estrogens; Hormone; Hormones; Hormones, Hormone Substitutes, and Hormone Antagonists; Human Data; Natural Product; Reproductive Effect; Tumor data.
2. Toxicity of ConjugatedEstrogens
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 1740mg/kg (1740mg/kg) | Drugs in Japan Vol. -, Pg. 178, 1990. | |
rat | LD50 | intraperitoneal | 325mg/kg (325mg/kg) | Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971. |
3. Uses of ConjugatedEstrogens
ConjugatedEstrogens is the commercial name for a compound cream of vaginally administered estrogens, consisting primarily of conjugated estrogens. It is available in oral (0.3/ 0.45/ 0.625/ 0.9/ 1.25 mg), IV, and topical form. ConjugatedEstrogens can be used for menopause and postmenopausal estrogen replacement therapy and is the most commonly used drugs.
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