Cyclopropylacetic acid supplier

Name
Cyclopropylacetic acid
EINECS -0
CAS No. 5239-82-7
Article Data27
CAS DataBase
Density 1.171 g/cm³
Solubility
Melting Point
Formula C₅H₈O₂
Boiling Point 191.7 °C at 760 mmHg
Molecular Weight 100.117
Flash Point 93.8 °C
Transport Information UN 3265 8/PG 2
Appearance
Safety 26-36/37/39-45
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms 2-Cyclopropaneaceticacid;2-Cyclopropylacetic acid;
PSA 37.30000
LogP 0.87110

Synthetic route

: 5617-88-9
cyclopropyl-malonic acid

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
at 160℃;	98%

: 6542-60-5
2-cyclopropylacetonitrile

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With water; potassium hydroxide In ethanol at 90℃; for 18h;	96%
With dihydrogen peroxide; sodium hydroxide In water at 0℃; for 48h; Reflux; Inert atmosphere;	83%
With dihydrogen peroxide; sodium hydroxide In water Reflux;	81%

: 75-11-6
diiodomethane

: 625-38-7
but-3-enoic acid

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With diethylzinc In toluene Ambient temperature;	75%
With hydrogenchloride

: 124-38-9
carbon dioxide

: 1,3-dioxoisoindolin-2-yl 2-cyclopropylacetate

A: 591-80-0
pent-4-enoic acid

B: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With (1,2-dimethoxyethane)dichloronickel(II); 2.9-dimethyl-1,10-phenanthroline; silver fluoride In N,N-dimethyl acetamide at 20℃; under 5171.62 Torr; for 24h;	A 7% B 21%

...Expand

: 186581-53-3, 908094-01-9
diazomethane

: 4023-34-1
cyclopropanecarboxylic acid chloride

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With diethyl ether Erwaermen des Reaktionsprodukts mit Ag2O in Methanol und mit wss. KOH;

: 56105-19-2
2-cyclopropylacetaldehyde

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With silver(l) oxide

: 14902-14-8
-triphenyl-phosphoran

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With sodium hydroxide

: 7379-74-0
β-vinyl-β-propiolactone

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With 9-borabicyclo[3.3.1]nonane dimer; sodium methylate 1.) THF, r.t., 6 h; 2.) r.t., 12 h; Yield given. Multistep reaction;

: 128871-21-6
cyclopropylketene

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With water Rate constant;

: 124-38-9
carbon dioxide

: 7051-34-5
cyclopropylcarbinyl bromide

A: 591-80-0
pent-4-enoic acid

B: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With magnesium In tetrahydrofuran at -120 - -30℃; Yield given. Yields of byproduct given;

...Expand

: 56-23-5
tetrachloromethane

: 1607-28-9
Bis(cyclopropylacetyl) peroxide

A: 124-38-9
carbon dioxide

B: 61919-47-9
cyclopropyl-acetic acid cyclopropylmethyl ester

C: 5239-82-7
cyclopropylacetic acid

...Expand

: 2566-44-1
1-cyclopropylethanol

aqueous potassium permanganate solution: aqueous potassium permanganate solution

A: 5239-82-7
cyclopropylacetic acid

B: 1759-53-1
cyclopropanecarboxylic acid

...Expand

: 42392-68-7
diethyl cyclopropylmalonate

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: aqueous NaOH View Scheme

: 2566-44-1
1-cyclopropylethanol

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: durch Dehydrierung an einem Kupfer-Silber-Katalysator 2: Ag2O View Scheme

jones reagent: jones reagent

: 56105-19-2
2-cyclopropylacetaldehyde

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With sulfuric acid In water; acetone
With sulfuric acid In water; acetone

: 2-(cyclopropanemethyl)-1,3-dithiane

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrahydrofuran 2: sulfuric acid / water; acetone View Scheme

: 6746-94-7
Cyclopropylacetylene

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
Stage #1: Cyclopropylacetylene With n-butyllithium In tetrahydrofuran at -78℃; for 1h; Stage #2: With 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran for 2h; Stage #3: With oxone In acetone at 50℃; for 12h;	475.6 mg

: 1432491-43-4
2-(2-cyclopropylethynyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 5239-82-7
cyclopropylacetic acid

Conditions

Conditions	Yield
With oxone\|\|potassium monopersulfate triple salt; water In acetone at 50℃; for 12h; Inert atmosphere;	475 mg

: 5239-82-7
cyclopropylacetic acid

: 124435-71-8
7-tert-butyl-3,3-dimethyl-2,3-dihydrobenzo[b]furan

: 1-(7-tert-butyl-2,3-dihydro-3,3-dimethyl-5-benzofuranyl)-2-cyclopropylethan-1-one

Conditions

Conditions	Yield
With trifluoroacetic anhydride at -20 - 20℃;	100%

: 885232-51-9
1-(4-chloro-benzyl)-5-fluoro-2-phenoxymethyl-6-piperazin-1-yl-1H-benzoimidazole

: 5239-82-7
cyclopropylacetic acid

: 1-{4-[3-(4-chloro-benzyl)-6-fluoro-2-phenoxymethyl-3H-benzoimidazol-5-yl]-piperazin-1-yl}-2-cyclopropyl-ethanone

Conditions

Conditions	Yield
Stage #1: cyclopropylacetic acid With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 0.0166667h; Stage #2: 1-(4-chloro-benzyl)-5-fluoro-2-phenoxymethyl-6-piperazin-1-yl-1H-benzoimidazole In N,N-dimethyl-formamide at 20℃; for 22h;	100%

: 1310036-75-9
[3-(4',5'-Difluoro-2'-methoxy-biphenyl-4-yloxymethyl)benzylamino]-acetic acid ethyl ester hydrochloride

: 5239-82-7
cyclopropylacetic acid

: 1310038-17-5
{(2-cyclopropyl-acetyl)-[3-(4',5'-difluoro-2'-methoxy-biphenyl-4-yloxymethyl)-benzyl]-amino}-acetic acid ethyl ester

Conditions

Conditions	Yield
With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In dichloromethane at 20℃;	100%

: 5239-82-7
cyclopropylacetic acid

: 6942-37-6
5-amino-2-bromo-benzoic acid methyl ester

: methyl 2-bromo-5-(2-cyclopropylacetamido)benzoate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃;	100%

: 5239-82-7
cyclopropylacetic acid

: 54322-65-5
cyclopropylacetyl chloride

Conditions

Conditions	Yield
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 25℃; for 4h;	99.6%
With oxalyl dichloride In dichloromethane at 20℃; for 4h;	98%
With thionyl chloride In dichloromethane at 60℃; for 2h;	90%

: 884538-52-7
methyl (2R,12Z,13aS,14aR,16aS)-6-amino-5,16-dioxo-2-[(5-pyridin-2-ylthieno[3,2-b]pyridin-7-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate

: 5239-82-7
cyclopropylacetic acid

: methyl (2R,12Z,13aS,14aR,16aS)-6-[(cyclopropylacetyl)amino]-5,16-dioxo-2-[(5-pyridin-2-ylthieno[3,2-b]pyridin-7-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane for 15.5h;	99%

: 1219511-65-5
C39H49BrN6O9S

: 5239-82-7
cyclopropylacetic acid

: 1219511-75-7
C39H47BrN6O8S

Conditions

Conditions	Yield
Stage #1: C39H49BrN6O9S With hydrogenchloride In dioxanes at 20℃; for 1h; Stage #2: cyclopropylacetic acid With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane at 20℃; for 18h;	99%

: 5239-82-7
cyclopropylacetic acid

: 337915-79-4
4-bromo-N2-methylbenzene-1,2-diamine

: 1447911-05-8
6-bromo-2-(cyclopropylmethyl)-1-methyl-1H-benzimidazole

Conditions

Conditions	Yield
Stage #1: cyclopropylacetic acid; 4-bromo-N2-methylbenzene-1,2-diamine With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: With acetic acid at 80℃; for 1h;	96%

: 5239-82-7
cyclopropylacetic acid

: 1630067-58-1
(R,E)-6-(benzyloxy)-1-(methoxymethoxy)hex-3-en-2-ol

: 1630067-83-2
(R,E)-6-(benzyloxy)-1-(methoxymethoxy)hex-3-en-2-yl 2-cyclopropylacetate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 7.5h; Inert atmosphere;	95.4%

: 884538-66-3
methyl (2R,6S,12Z,13aS,14aR,16aS)-6-amino-5,16-dioxo-2-[(2-pyridin-2-ylthieno[2,3-d]pyrimidin-4-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate

: 5239-82-7
cyclopropylacetic acid

: methyl (2R,6S,12Z,13aS,14aR,16aS)-6-[(cyclopropylacetyl)amino]-5,16-dioxo-2-[(2-pyridin-2-ylthieno[2,3-d]pyrimidin-4-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate

Conditions

Conditions	Yield
Stage #1: methyl (2R,6S,12Z,13aS,14aR,16aS)-6-amino-5,16-dioxo-2-[(2-pyridin-2-ylthieno[2,3-d]pyrimidin-4-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate; cyclopropylacetic acid With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane for 15h; Stage #2: With citric acid In dichloromethane; ethyl acetate pH=4.5;	95%

: 766545-20-4
2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride

: 5239-82-7
cyclopropylacetic acid

: 2-chloro-6-(cyclopropylacetyl)-5,6,7,8-tetrahydro-1,6-naphthyridine

Conditions

Conditions	Yield
Stage #1: cyclopropylacetic acid With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.25h; Stage #2: 2-chloro-5,6,7,8-tetrahydro[1,6]naphthyridine hydrochloride With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h;	95%

: 5239-82-7
cyclopropylacetic acid

: (±)-(2R,3R)-2-azido-3-phenyl-3-hydroxypropionic acid methyl ester

: (±)-(2R,3R)-2-azido-3-(2-cyclopropylacetoxy)-3-phenylpropionic acid methyl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h; Steglich Esterification;	95%

: 5239-82-7
cyclopropylacetic acid

: (±)-(2R,3R)-2-azido-3-hydroxy-3-(3-methoxyphenyl)propionic acid methyl ester

: (±)-(2R,3R)-2-azido-3-(2-cyclopropylacetoxy)-3-(3-methoxyphenyl)propionic acid methyl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h; Steglich Esterification;	94%

: 5239-82-7
cyclopropylacetic acid

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 227322-00-1
2-cyclopropyl-N-methoxy-N-methyl-acetamide

Conditions

Conditions	Yield
Stage #1: cyclopropylacetic acid With 1,1'-carbonyldiimidazole In dichloromethane at 25℃; for 1h; Inert atmosphere; Stage #2: N,O-dimethylhydroxylamine*hydrochloride In dichloromethane at 25℃; for 12h;	93.96%
Stage #1: cyclopropylacetic acid With 1,1'-carbonyldiimidazole In dichloromethane at 20℃; Stage #2: N,O-dimethylhydroxylamine*hydrochloride In dichloromethane	89%
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃;	84%

: 5239-82-7
cyclopropylacetic acid

: 62-53-3
aniline

: 5687-69-4
2-cyclopropyl-N-phenylacetamide

Conditions

Conditions	Yield
Stage #1: cyclopropylacetic acid; aniline With 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate In N,N-dimethyl-formamide at 0℃; for 0.5h; Inert atmosphere; Stage #2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere;	93%
With 1-methyl-3-(4-sulfonylbutyl)-1H-imidazol-3-ium trifluoromethanesulfonate at 96 - 100℃; for 7h; chemoselective reaction;	42%

: 5239-82-7
cyclopropylacetic acid

: 126-81-8
dimedone

: 908117-02-2
2-(2-cyclopropylacetyl)-5,5-dimethylcyclohexane-1,3-dione

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 16.2h;	92%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 25℃; for 14h;	85%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 25℃;	85%

: 5239-82-7
cyclopropylacetic acid

: 130517-92-9
(2R,3R)-2-azido-3-phenyl-3-hydroxypropionic acid methyl ester

: (2R,3R)-2-azido-3-(2-cyclopropylacetoxy)-3-phenylpropionic acid methyl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h; Steglich Esterification;	92%

: 5239-82-7
cyclopropylacetic acid

: 133179-94-9
(2S,3S)-2-azido-3-phenyl-3-hydroxypropionic acid methyl ester

: (2S,3S)-2-azido-3-(2-cyclopropylacetoxy)-3-phenylpropionic acid methyl ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h; Steglich Esterification;	92%

: 5239-82-7
cyclopropylacetic acid

: 163765-44-4
(R)-tert-butyl 3-methylpiperazine-1-carboxylate

: (R)-tert-butyl 4-(2-cyclopropylacetyl)-3-methylpiperazine-1-carboxylate

Conditions

Conditions	Yield
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;	92%
With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 16h;	92%

: 95-14-7
1,2,3-Benzotriazole

: 5239-82-7
cyclopropylacetic acid

: 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-cyclopropylethan-1-one

Conditions

Conditions	Yield
Stage #1: 1,2,3-Benzotriazole With thionyl chloride In dichloromethane at 20℃; for 0.5h; Inert atmosphere; Stage #2: cyclopropylacetic acid for 6h; Inert atmosphere; Cooling with ice;	92%
Stage #1: 1,2,3-Benzotriazole With thionyl chloride In dichloromethane at 20℃; for 0.5h; Stage #2: cyclopropylacetic acid In dichloromethane at 20℃; for 4h;	91%

: 5239-82-7
cyclopropylacetic acid

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

1,1'-carbonyldiimidazole: 1,1'-carbonyldiimidazole

: 227322-00-1
2-cyclopropyl-N-methoxy-N-methyl-acetamide

Conditions

Conditions	Yield
Stage #1: cyclopropylacetic acid; 1,1'-carbonyldiimidazole In dichloromethane at 15 - 25℃; for 2h; Stage #2: N,O-dimethylhydroxylamine*hydrochloride In dichloromethane at 20 - 25℃; for 15h;	90.5%

...Expand

: 5239-82-7
cyclopropylacetic acid

: 34108-21-9
methyl cyclopropylacetate

Conditions

Conditions	Yield
With sulfuric acid In methanol	90%
Multi-step reaction with 2 steps 1: (COCl)2, DMF / benzene / 3 h / Ambient temperature 2: pyridine / Ambient temperature View Scheme

: 5239-82-7
cyclopropylacetic acid

: 150-76-5
4-methoxy-phenol

: 4-methoxyphenyl 2-bromo-2-cyclopropylacetate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In diethyl ether at 20℃; for 5h; Inert atmosphere;	90%

: 884538-80-1
methyl (2R,6S,12Z,13aS,14aR,16aS)-6-amino-5,16-dioxo-2-[(2-pyridin-2-ylthieno[3,2-d]pyrimidin-4-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate

: 5239-82-7
cyclopropylacetic acid

: methyl (2R,6S,12Z,13aS,14aR,16aS)-6-[(cyclopropylacetyl)amino]-5,16-dioxo-2-[(2-pyridin-2-ylthieno[3,2-d]pyrimidin-4-yl)oxy]-1,2,3,6,7,8,9,10,11,13a,14,15,16,16a-tetradecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecine-14a(5H)-carboxylate

Conditions

Conditions	Yield
With dimethyl amine; triethylamine; HATU at 50℃; for 1.5h;	89%

: 5239-82-7
cyclopropylacetic acid

: 100-39-0
benzyl bromide

: 59698-18-9
benzyl 2-cyclopropylacetate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	89%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 16h;
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 90℃; Inert atmosphere;

: 5239-82-7
cyclopropylacetic acid

: 8-((3R,4S)-4-methylpyrrolidin-3-yl)-3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazine dihydrobromide

: 1428243-48-4
2-cyclopropyl-1-((3S,4R)-3-methyl-4-(3-tosyl-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)pyrrolidin-1-yl)ethanone

Conditions

Conditions	Yield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 16h;	89%

: 5239-82-7
cyclopropylacetic acid

: 87768-65-8
N-β-Z-L-diaminopropionic acid methyl ester

: C17H22N2O5

Conditions

Conditions	Yield
With 1-hydroxy-7-aza-benzotriazole; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 1h;	87%

: 497-25-6
dimethylenecyclourethane

: 5239-82-7
cyclopropylacetic acid

: 1330681-58-7
3-(2-cyclopropylacetyl)oxazolidin-2-one

Conditions

Conditions	Yield
Stage #1: dimethylenecyclourethane; cyclopropylacetic acid With lithium chloride In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere; Stage #2: With pivaloyl chloride; triethylamine In tetrahydrofuran at 0 - 20℃; for 2.33333h; Inert atmosphere;	87%

Cyclopropylacetic acid Specification

The Cyclopropylacetic acid, with the CAS registry number 5239-82-7, is also known as Cyclopropyl acetic acid. This chemical's molecular formula is C₅H₈O₂ and molecular weight is 100.12. What's more, its IUPAC name is called 2-Cyclopropylacetic acid. It should be stored in a cool, dry and well-ventilated place.

Physical properties about Cyclopropylacetic acid are: (1)ACD/LogP: 0.578; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -0.23; (4)ACD/LogD (pH 7.4): -2.03; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 7.57; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 37.3 Å²; (13)Index of Refraction: 1.491; (14)Molar Refractivity: 24.726 cm³; (15)Molar Volume: 85.437 cm³; (16)Surface Tension: 49.00 dyne/cm; (17)Density: 1.172 g/cm³; (18)Flash Point: 93.757 °C; (19)Enthalpy of Vaporization: 47.172 kJ/mol; (20)Boiling Point: 191.73 °C at 760 mmHg; (21)Vapour Pressure: 0.22 mmHg at 25 °C.

Preparation of Cyclopropylacetic acid: this chemical can be prepared by Cyclopropyl-acetonitrile. This reaction needs reagent 25percent aq. NaOH at temperature of 130-140 °C. The reaction time is 7 hours.

Cyclopropylacetic acid can be prepared by Cyclopropyl-acetonitrile.

Uses of Cyclopropylacetic acid: it is used to produce other chemicals. For example, it can react with 1-Hydroxy-1H-pyridine-2-thione to get 1-{[(Cyclopropylmethyl)carbonyl]oxy}-2(1H)-pyridinethione. The reaction occurs with reagents p-(dimethylamino)pyridine, dicyclohexylcarbodiimide and solvent CH₂Cl₂ at ambient temperature. The yield is 45 %.

Cyclopropylacetic acid can react with 1-Hydroxy-1H-pyridine-2-thione to get 1-{[(Cyclopropylmethyl)carbonyl]oxy}-2(1H)-pyridinethione.

When you are dealing with this chemical, you should be very careful. This chemical is inflammation to the skin or other mucous membranes and may destroy living tissue on contacting. What's more, it may cause burns. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. In case of contacting with eyes or skin, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: O=C(O)CC1CC1
(2) InChI: InChI=1S/C5H8O2/c6-5(7)3-4-1-2-4/h4H,1-3H2,(H,6,7)
(3) InChIKey: KVVDRQDTODKIJD-UHFFFAOYSA-N

Product Name

Cyclopropylacetic acid

Synthetic route

Cyclopropylacetic acid Specification

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