DITHIOOXAMIDE supplier | CasNO.79-40-3

Name
Dithiooxamide
EINECS 201-203-9
CAS No. 79-40-3
Article Data16
CAS DataBase
Density 1.523 g/cm³
Solubility Soluble in alcohols. Slightly soluble in water. Insoluble in ether
Melting Point ≥300 °C(lit.)
Formula C₂H₄N₂S₂
Boiling Point 252.1 °C at 760 mmHg
Molecular Weight 120.199
Flash Point 106.2 °C
Transport Information
Appearance orange to brown crystalline powder
Safety 36/37
Risk Codes 22-36/37/38
Molecular Structure
Hazard Symbols Xn
Synonyms Oxamide,dithio- (8CI);Dithiooxalic acid diamide;Ethanedithioamide;Hydrorubeanic acid;NSC 1893;Rubean;Rubeane;Rubeanic acid;
PSA 116.22000
LogP 0.95920

Synthetic route

: 471-46-5
Oxalamide

: 79-40-3
dithiooxamide

Conditions

Conditions	Yield
With Lawessons reagent In acetonitrile Heating;	67.36%

: 14011-21-3
2-nitroacetamide

A: 16475-48-2
thiooxalamide

B: 79-40-3
dithiooxamide

Conditions

Conditions	Yield
With Lawessons reagent In toluene at 80℃; for 0.5h; Other reagent;	A 32% B 14%
With tetraphosphorus decasulfide In 1,4-dioxane at 80℃; for 0.2h; other reagent;	A 21% B 14%

: 460-19-5
ethanedinitrile

: 79-40-3
dithiooxamide

Conditions

Conditions	Yield
With hydrogen sulfide in alkoh.Loesung;
With sodium hydrogensulfide das Natriumsalz entsteht, in alkoholischer Loesung;
With cyclohexane-1,1-dithiol In ethanol
With hydrogen sulfide in alkoh.Loesung;
With hydrogenchloride; sodium hydrogensulfide; water

: 64-17-5
ethanol

: 100-63-0
phenylhydrazine

thiooxalamic acid nitrile: thiooxalamic acid nitrile

A: 178168-62-2
amino-(N'-phenyl-hydrazono)-acetonitrile

B: 7783-06-4
hydrogen sulfide

C: 79-40-3
dithiooxamide

...Expand

: 79844-63-6
dimethyl thiooxalimidate

: 7783-06-4
hydrogen sulfide

: 79-40-3
dithiooxamide

: 460-19-5
ethanedinitrile

H2S (2 mol): H2S (2 mol)

: 79-40-3
dithiooxamide

: 460-19-5
ethanedinitrile

: 7783-06-4
hydrogen sulfide

A: 471-24-9
Flaveanwasserstoff

B: 79-40-3
dithiooxamide

...Expand

: 48044-14-0, 127569-88-4, 1010689-97-0
Cd(DTO)Br2

A: 79-40-3
dithiooxamide

B: cadmium(II) bromide

Conditions

Conditions	Yield
Kinetics; decomposition in a N2 gas flow;

: 40086-66-6
2-Bromoacetylpyridine

: 79-40-3
dithiooxamide

: 4,4'-di(pyrid-2-yl)-2,2'-bithiazole

Conditions

Conditions	Yield
In ethanol at 78℃;	100%

: 109-76-2
Trimethylenediamine

: 79-40-3
dithiooxamide

: 21786-88-9
1,1',4,4',5,5',6,6'-octahydro-2,2'-bipyrimidine

Conditions

Conditions	Yield
Stage #1: dithiooxamide With ethyl bromide In ethanol at 60℃; for 4h; Inert atmosphere; Schlenk technique; Stage #2: Trimethylenediamine In ethanol at 60 - 80℃; for 1.33333h; Inert atmosphere; Schlenk technique;	100%

: 645-36-3
2,2-diethoxy-ethanamine

: 79-40-3
dithiooxamide

: N,N'-(2,2-diethoxyethyl)dithiooxamide

Conditions

Conditions	Yield
In ethanol	99%

: 79-40-3
dithiooxamide

: 471-46-5
Oxalamide

Conditions

Conditions	Yield
With bismuth(III) nitrate In acetonitrile for 0.25h; Heating;	99%
With Oxone In acetonitrile for 1h; Heating;	97%
With 12-tungstosilic acid In acetonitrile for 1.5h; Reflux;	97%

: 79-40-3
dithiooxamide

: 762-42-5
dimethyl acetylenedicarboxylate

: 603-35-0
triphenylphosphine

: 1204685-94-8
dimethyl 2-[(2-amino-2-thioxoethanthioyl)amino]-3-(1,1,1-triphenyl-λ5-phosphanylidene)succinate

Conditions

Conditions	Yield
In hexane; ethyl acetate at 20℃; for 1h;	95%

...Expand

: 98416-35-4
N-(2-benzene-2,2-dichloroethylidene)-4-chlorobenzenesulfonamide

: 79-40-3
dithiooxamide

: 1377583-54-4
N-[2,2-dichloro-1-(4-chlorophenylsulfonylamino)-2-phenylethyl]ethanedithioamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 15h;	95%

: 79-40-3
dithiooxamide

: 16475-48-2
thiooxalamide

Conditions

Conditions	Yield
With 2,2'-bipyridinium chlorochromate In acetonitrile for 0.0833333h; Product distribution; Further Variations:; Reagents; Temperatures; without microwave irradiation; solvent-free; microwave irradiation;	94%

: 40396-53-0
1-(3-bromophenyl)-2-phenylethan-1-one

: 79-40-3
dithiooxamide

: 1260214-92-3
5-amino-2-benzyl-2-(3-bromophenyl)-2H-imidazole-4-thiol

Conditions

Conditions	Yield
With ammonia In methanol at 150℃; for 1h; Microwave irradiation;	94%

: 79-40-3
dithiooxamide

: 2-bromo-7-methyl-5-oxo-5H-1,3,4-thiadiazolo<3,2-a>pyrimidine

: C8H7N5S3O*HBr

Conditions

Conditions	Yield
In ethanol for 2h; Heating;	93%

: bis(acetylacetonato)dioxidomolybdenum(VI)

: 79-40-3
dithiooxamide

: 1414938-99-0
bis(dithiooxamidate)dioxomolybdenum(VI)

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃; for 15h;	92%

: 1117953-26-0
2-Bromo-1-(5-hexylthiophen-2-yl)ethanone

: 79-40-3
dithiooxamide

: 4,4'-Bis(5-hexylthiophen-2-yl)-2,2'-bithiazole

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 90℃; for 12h; Inert atmosphere;	91.6%

: 3385-78-2
trimethyl indium

: 79-40-3
dithiooxamide

: 86356-19-6
((CH3)2In)2(NHCS)2

Conditions

Conditions	Yield
In toluene byproducts: CH4; under N2, to dithiooxamide dissolved or suspended in toluene added dropwise alkyl component (pure or dild. with toluene); elem. anal.;	90%

: oxopentachlororhenic acid

: 79-40-3
dithiooxamide

: 104067-54-1, 88784-48-9
dithiooxamide ReOCl3 complex

Conditions

Conditions	Yield
With HCl In acetic acid under N2 soln. of ligand in AcOH/HCl was added to soln. of Re compd. inthe same solvent; filtration, washing with AcOH/HCl followed by petrolem ether; drying invac. over NaOH; elem. anal.;	90%

: 79-40-3
dithiooxamide

: 603-35-0
triphenylphosphine

: 762-21-0
acetylenedicarboxylic acid diethyl ester

: 1204685-95-9
diethyl 2-[(2-amino-2-thioxoethanthioyl)amino]-3-(1,1,1-triphenyl-λ5-phosphanylidene)succinate

Conditions

Conditions	Yield
In hexane; ethyl acetate at 20℃; for 1h;	90%

...Expand

: 73121-60-5
1-bromo-undecan-2-one

: 79-40-3
dithiooxamide

: 180729-91-3
4,4'-dinonyl-2,2'-bithiazole

Conditions

Conditions	Yield
In ethanol for 6h; Heating;	89%
In ethanol Hantzsch Thiazole Synthesis; Inert atmosphere; Schlenk technique;

: 23754-53-2
3-(α-bromoacetyl)-4-hydroxy-6-methyl-2H-pyran-2-one

: 79-40-3
dithiooxamide

: 1295500-84-3
4-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)thiazole-2-carbothioamide

Conditions

Conditions	Yield
In ethanol for 0.166667h; Hantzsch reaction; Reflux; Microwave irradiation;	88%

: 79-40-3
dithiooxamide

: 236404-04-9
N-(2-benzene-2,2-dichloroethylidene)-4-methylbenzenesulfonamide

: 1377583-52-2
N-[2,2-dichloro-1-(4-methylphenylsulfonylamino)-2-phenylethyl]ethanedithioamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 15h;	88%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 79-40-3
dithiooxamide

: 21634-42-4
dibenzo[b,i]thianthrene-5,7,12,14-tetraone

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 50℃; for 10h;	88%

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 79-40-3
dithiooxamide

: 96354-84-6
2,2'-bis(naphtho<2,3-d>thiazole-4,9-dione)

Conditions

Conditions	Yield
With sodium hydrogencarbonate In ethanol for 2h; Heating;	86%
With triethylamine In N,N-dimethyl-formamide at 50℃; for 10h;	57%

: 75-64-9
tert-butylamine

: 79-40-3
dithiooxamide

: 26818-54-2
N,N'-Bis(tert-butyl)dithioxamid

Conditions

Conditions	Yield
In ethanol 1.) 40 deg C, 2.) 5 h, RT;	85%

: nickel(II) chloride hexahydrate

: 79-40-3
dithiooxamide

: ((NH2)2(CS)2)2NiCl2*2H2O

Conditions

Conditions	Yield
In ethanol refluxed 1-2.5 h, 1:1 mol. ratio, concd.; washed (ethanol), dried in vac. over P2O5; elem.anal.;	85%

: Mo2(N,N'-di-p-anisyl-formamidinato)3(O2CCH3)

: 124-41-4
sodium methylate

: 79-40-3
dithiooxamide

: [Mo2(N,N'-di-p-anisylformamidinato)3]2(dithiooxamidato)

Conditions

Conditions	Yield
In tetrahydrofuran; methanol byproducts: NaCH3COO, CH3OH; (N2); NaOCH3 in MeOH added to a soln. of Mo complex and ligand in THF, stirred at ambient temp. for 2 h; evapd. (vac.), extd. (CH2Cl2), filtered, concd. (vac.), pptd. (EtOH), washed (EtOH and hexanes), dried (vac.), dissolved in CH2Cl2, layered withhexanes, crystd. for 3 d; elem. anal.;	85%

...Expand

: 98416-35-4
N-(2-benzene-2,2-dichloroethylidene)-4-chlorobenzenesulfonamide

: 79-40-3
dithiooxamide

: 1377583-60-2
N,N'-bis[2,2-dichloro-1-(4-chlorophenylsulfonylamino)-2-phenylethyl]ethanebis(thioamide)

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 15h;	85%

: 79-40-3
dithiooxamide

: 335330-07-9
1-acetyl-1,2,3,4-tetrahydro-9H-carbazole

: (Z)-N1-[1-(2,3,4,9-tetrahydro-1H-carbazol-1-yl)ethylidene]ethanebis(thioamide)

Conditions

Conditions	Yield
With acetic acid for 0.0166667h; Microwave irradiation; Green chemistry;	85%

: 31949-21-0
bromomethyl 2-methoxyphenyl ketone

: 79-40-3
dithiooxamide

: 1242469-34-6
C20H16N2O2S2

Conditions

Conditions	Yield
In ethanol at 20℃; for 5h; Reflux;	84%
In ethanol

: 90134-10-4
4-(N,N-dibutylamino)benzaldehyde

: 79-40-3
dithiooxamide

: 1442657-00-2
C32H44N4S2

Conditions

Conditions	Yield
In propan-1-ol at 120℃; Schlenk technique; Inert atmosphere;	83%

: 5122-16-7
1-(2,3,4,5,6-pentafluorophenyl)-2-bromo-1-ethanone

: 79-40-3
dithiooxamide

: 1422972-57-3
4,4'-bis(perfluorophenyl)-2,2'-bithiazole

Conditions

Conditions	Yield
In ethanol Hantzsch Thiazole Synthesis; Reflux;	83%

: 26818-08-6
1-bromooctan-2-one

: 79-40-3
dithiooxamide

: 180729-92-4
4,4'-dihexyl 2,2'-bithiazole

Conditions

Conditions	Yield
In ethanol for 4h; Reflux;	81%
In ethanol for 4h; Reflux; Inert atmosphere;	80.8%
In ethanol for 4h; Reflux;
In ethanol
In ethanol

: 55596-11-7
N-(2,2,2-trichloroethylidene)benzenesulfonamide

: 79-40-3
dithiooxamide

: 1257096-40-4
N-[2,2,2-trichloro-1-(phenylsulfonylamino)ethyl]ethanedithioamide

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 90 - 100℃; for 12h;	81%

: 79-40-3
dithiooxamide

: 204905-77-1
3,4-ethylenedioxythiophene-2-carboxaldehyde

: 1544476-48-3
2,5-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)thiazolo[5,4-d]thiazole

Conditions

Conditions	Yield
Stage #1: dithiooxamide; 3,4-ethylenedioxythiophene-2-carboxaldehyde In nitrobenzene at 150℃; for 0.5h; Inert atmosphere; Microwave irradiation; Stage #2: With chloranil In tetrahydrofuran; nitrobenzene for 0.166667h; Reflux; Inert atmosphere;	81%

DITHIOOXAMIDE Chemical Properties

Molecular Formula:C₂H₄N₂S₂
Molecular Weight:120.20
EINECS:201-203-9
Density:1.523 g/cm³
Melting Point:>300 °C
Boiling Point:252.1 °C at 760 mmHg
Flash Point:106.2 °C
Solubility:negligible
Stability:Stable.

Dithiooxamide's Synonyms: DITHIOOXALAMIDE;DITHIOOXALIC DIAMIDE;DITHIOOXAMIDE;ETHANEDITHIOAMIDE;RUBEANE;RUBEAN-HYDROGEN;RUBEANIC ACID;dithiono-oxalicacidiamide

DITHIOOXAMIDE Uses

Insecticide.Reagent for the spectrophotometric determination of palladium in the presence of piperidine, quinoline, a-picoline and collidine.

DITHIOOXAMIDE Toxicity Data With Reference

1.	orl-rat LDLo:500 mg/kg	NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. 5 (1953),43.
2.	orl-mus LD50:350 mg/kg	FATOAO Farmakologiya i Toksikologiya (Moscow). 28 (1965),230.
3.	ipr-mus LD50:100 mg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD277-689 .
4.	ivn-mus LD50:56 mg/kg	CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) NX#04475 .

DITHIOOXAMIDE Consensus Reports

Reported in EPA TSCA Inventory.

DITHIOOXAMIDE Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.

Dithiooxamide's Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 36/37
WGK Germany 3
RTECS RP1575000
HS Code 29309070

Product Name

Dithiooxamide

Synthetic route

DITHIOOXAMIDE Chemical Properties

DITHIOOXAMIDE Uses

DITHIOOXAMIDE Toxicity Data With Reference

DITHIOOXAMIDE Consensus Reports

DITHIOOXAMIDE Safety Profile

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