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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

DL-Pantolactone

Cas:79-50-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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GIHI CHEMICALS CO.,LIMITED

Product Name:DL-Pantolactone CAS No.: 79-50-5 Chemical formula: C6H10O3 Molecular weight:130.14 Product Usage: Pharmaceutical intermediates Packaging and Shipping: 25kgs /drum, or customized. Storage: Notes: Keep stored in cool, dry condit

Biggest manufacturer of DL-Pantolactone

Cas:79-50-5

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic PANTOLACTONE 79-50-5 Manufacturer

Cas:79-50-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

DL-Pantolactone

Cas:79-50-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

79-50-5 DL-Pantolactone

Cas:79-50-5

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

CAS No.79-50-5 DL-Pantolactone Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relati

CAS No.79-50-5 DL-Pantolactone

Cas:79-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 79-50-5 with best quality

Cas:79-50-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2(3H)-Furanone,dihydro-3-hydroxy-4,4-dimethyl- 79-50-5

Cas:79-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

DL-Pantolactone CAS:79-50-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

DL-Pantolactone CAS:79-50-5

Cas:79-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2(3H)-Furanone,dihydro-3-hydroxy-4,4-dimethyl-

Cas:79-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

best price,best quality and fast delivery assurance available in sample product and customization with years of export experience along with excellent quality, advanced services and competitive prices the quality of products conform u

DL-Pantolactone CAS NO.79-50-5

Cas:79-50-5

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:79-50-5

Cas:79-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Dl-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

DL-Pantolactone

Cas:79-50-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. Kind Pharma has its own laboratory, we can do analytical testing for API (Active Pharmaceutical Ingredient), pharmaceutical intermediate, pesticide intermediate, additive and other chemical products, so it

DL-Pantolactone

Cas:79-50-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

DL-PANTOLACTONE

Cas:79-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

DL-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hefei Zhaobo Technology Co., Ltd.

Our Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci

DL-Pantolactone CAS.79-50-5

Cas:79-50-5

Min.Order:1 Kilogram

FOB Price: $150.0 / 180.0

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

DL-Pantolactone

Cas:79-50-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

DL-Pantolactone Basic information Product Name: DL-Pantolactone Synonyms: 2(3H)-Furanone, dihydro-3-hydroxy-4,4-dimethyl-, (+-)-;DL-alpha-Hydroxy-beta,beta-dimethyl-alpha-butyrolactone;DL-ALPHA-HYDROXY-BETA,BETA-DIMETHYL-GAMME-BUTYROLACTONE;DL

DL-Pantolactone

Cas:79-50-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

79-50-5 CAS NO.79-50-5

Cas:79-50-5

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

DL-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

DL-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Other

inquiry

Wuhan Fortuna Chemical Co.,Ltd

good quality and cheap price Package:25kg/200kg Application:as intermediates Transportation:by courier/sea/air

DL-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec DL-Pantolactone 1kg

Cas:79-50-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

DL-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Dl-Pantolactone 90%

Cas:79-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

DL-Pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

Dl-pantolactone

Cas:79-50-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

A

pantolactone
79-50-5

pantolactone

B

3-amino propanoic acid
107-95-9

3-amino propanoic acid

Conditions
ConditionsYield
With hydrogenchloride In water at 80℃; for 1.75h; Rate constant;A 100%
B 100%
pantothenic acid sodium salt
75033-16-8

pantothenic acid sodium salt

A

pantolactone
79-50-5

pantolactone

B

3-amino propanoic acid
107-95-9

3-amino propanoic acid

Conditions
ConditionsYield
With hydrogenchloride In water at 80℃; for 1.25h; Rate constant;A 100%
B 100%
ketopantolactone
13031-04-4

ketopantolactone

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With hydrogen; Et4N99%
With F6P(1-)*C20H36IrN6P2(1+); hydrogen In water at 80℃; under 15001.5 Torr; for 4h; Catalytic behavior; Reagent/catalyst; Time; Autoclave; Green chemistry;99.9%
With iron(II) triflate; phenanthridine; triiron dodecarbonyl; hydrogen In 1,4-dioxane at 65℃; under 37503.8 Torr; for 24h; Autoclave;91%
sodium cyanide
773837-37-9

sodium cyanide

2,2-dimethyl-3-hydroxypropionaldehyde
597-31-9

2,2-dimethyl-3-hydroxypropionaldehyde

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With sulfuric acid for 3h; pH=9.5; Reflux;98.9%
With sulfuric acid In water at 100℃; for 1h;86.9%
(+-)-2,4-dihydroxy-3,3-dimethyl-butyric acid
470-29-1

(+-)-2,4-dihydroxy-3,3-dimethyl-butyric acid

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With sulfuric acid at 80 - 85℃; for 3h; Temperature;98.3%
2,2-dimethyl-3-hydroxypropionaldehyde
597-31-9

2,2-dimethyl-3-hydroxypropionaldehyde

hydrogen cyanide
74-90-8

hydrogen cyanide

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Stage #1: 2,2-dimethyl-3-hydroxypropionaldehyde; hydrogen cyanide In water at 0 - 10℃; for 0.25h;
Stage #2: With sulfuric acid for 1h; Reflux;
93.1%
Verseifung des Reaktionsprodukts mit Salzsaeure;
(R,S)-2,4-Dihydroxy-3,3-dimethylbutyronitrile
10232-92-5

(R,S)-2,4-Dihydroxy-3,3-dimethylbutyronitrile

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With sulfuric acid for 6h; Reagent/catalyst; Reflux;92.5%
With ammonium hydroxide; sulfuric acid at 94 - 96℃; under 435.044 Torr; for 2.25h; pH=5.0; Pressure; Temperature; pH-value; Inert atmosphere;
pantolactone p-nitrobenzoate
134734-33-1

pantolactone p-nitrobenzoate

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With lithium hydroxide In methanol; water for 0.166667h; Ambient temperature;90%
N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide
100618-94-8

N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide

A

pantolactone
79-50-5

pantolactone

B

1-benzyl-3-hydroxy-4,4-dimethylpyrrolidin-2-one

1-benzyl-3-hydroxy-4,4-dimethylpyrrolidin-2-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In diethylene glycol dimethyl ether for 5h; Heating;A 14 % Spectr.
B 69%
glyoxylic acid ethyl ester
924-44-7

glyoxylic acid ethyl ester

2-methyl-propan-1-ol
78-83-1

2-methyl-propan-1-ol

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Stage #1: glyoxylic acid ethyl ester; 2-methyl-propan-1-ol With N-(2-hydroxyethyl)pyrrolidine-2-carboxamide In toluene; tert-butyl alcohol at 20℃; for 24h;
Stage #2: With [RhCl2(p-cymene)]2; sodium formate In water; toluene; tert-butyl alcohol Reagent/catalyst; Temperature; Inert atmosphere;
62%
N-heptyl-2,4-dihydroxy-3,3-dimethylbutyramide
43180-77-4

N-heptyl-2,4-dihydroxy-3,3-dimethylbutyramide

A

pantolactone
79-50-5

pantolactone

B

1-heptyl-3-hydroxy-4,4-dimethylpyrrolidin-2-one

1-heptyl-3-hydroxy-4,4-dimethylpyrrolidin-2-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid In diethylene glycol dimethyl ether for 15h; Heating;A 41%
B 15%
(R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide
4417-86-1

(R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide

A

DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid lactam
70006-38-1

DL-4-amino-2-hydroxy-3,3-dimethylbutanoic acid lactam

B

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With ammonia; toluene-4-sulfonic acid In methanol at 250℃; under 7220 - 11400 Torr; for 4h; Heating;A 9 % Spectr.
B 40%
formaldehyd
50-00-0

formaldehyd

sodium 3-methyl-2-oxobutyrate
3715-29-5

sodium 3-methyl-2-oxobutyrate

A

ketopantolactone
13031-04-4

ketopantolactone

B

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With hydrogenchloride; potassium carbonate 1.) H2O, 38-40 deg C, (well controlled addition of formaldehyde); Yield given. Multistep reaction. Yields of byproduct given;
Conditions
ConditionsYield
With water; sodium 1,2-naphthoquinone-4-sulfonate In ethanol Kinetics; Rate constant; Mechanism; various temperatures, times, concentrations, pH, ionic strengths, and dielectric constants;
isobutyraldehyde
78-84-2

isobutyraldehyde

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

A

ketopantolactone
13031-04-4

ketopantolactone

B

dihydro-4,4-dimethyl-5-(1-methylethyl)-2,3-furandione
96305-22-5

dihydro-4,4-dimethyl-5-(1-methylethyl)-2,3-furandione

C

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With formaldehyd; sodium methylate 1.) methanol, 10 deg C, 20 min, 2.) methanol, 40 deg C, 20 min; Yield given. Multistep reaction. Yields of byproduct given;
(RS)-2-acetoxy-3,3-dimethyl-γ-butyrolactone
28227-35-2

(RS)-2-acetoxy-3,3-dimethyl-γ-butyrolactone

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With potassium hydroxide In methanol Heating; Yield given;
formaldehyd
50-00-0

formaldehyd

potassium-salt of/the/ α-oxo-isovaleric acid

potassium-salt of/the/ α-oxo-isovaleric acid

A

ketopantolactone
13031-04-4

ketopantolactone

B

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With potassium carbonate Erwaermen der mit wss. Salzsaeure angesaeuerten Reaktionsloesung;
(+-)-2,4-dihydroxy-3,3-dimethyl-butyrimidic acid-4-lactone

(+-)-2,4-dihydroxy-3,3-dimethyl-butyrimidic acid-4-lactone

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With water
ketopantolactone
13031-04-4

ketopantolactone

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

A

pantolactone
79-50-5

pantolactone

B

2,2-diethyl-3-hydroxy-4,4-dimethyltetrahydrofuran

2,2-diethyl-3-hydroxy-4,4-dimethyltetrahydrofuran

Conditions
ConditionsYield
In tetrahydrofuran at 0℃; for 1h; Title compound not separated from byproducts;
2,4-dihydroxy-N-phenyl-3,3-dimethylbutyramide
565430-86-6

2,4-dihydroxy-N-phenyl-3,3-dimethylbutyramide

A

rac-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone
70006-37-0

rac-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone

B

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In diethylene glycol dimethyl ether for 15h; Heating;A 40 % Spectr.
B 53 % Spectr.
(R)-Pantolacton
599-04-2

(R)-Pantolacton

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
With Lactobacillus paracasei DSM 20207 In water at 42℃; for 24h; pH=6; Product distribution; Further Variations:; Reagents;
N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide
100618-94-8

N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: 14 percent Spectr. / p-TsOH*H2O / bis-(2-methoxy-ethyl) ether / 5 h / Heating
2.1: n-BuLi / tetrahydrofuran; hexane / 3 h / 0 °C
2.2: 59 percent / tetrahydrofuran; hexane / 12 h / 20 °C
3.1: 53 percent Spectr. / p-TsOH*H2O / bis-(2-methoxy-ethyl) ether / 15 h / Heating
View Scheme
2,4-dihydroxy-N-phenyl-3,3-dimethylbutyramide
565430-86-6

2,4-dihydroxy-N-phenyl-3,3-dimethylbutyramide

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 53 percent Spectr. / p-TsOH*H2O / bis-(2-methoxy-ethyl) ether / 15 h / Heating
2: 100 percent / methanol / 24 h / 20 °C
3: 14 percent Spectr. / p-TsOH*H2O / bis-(2-methoxy-ethyl) ether / 5 h / Heating
View Scheme
(3R)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl methanesulfonate
20374-32-7

(3R)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl methanesulfonate

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 38 percent / 18-crown-6 / benzene / 48 h / Heating
2: 5percent KOH / methanol / Heating
View Scheme
Chloro-methanesulfonic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester
182243-70-5

Chloro-methanesulfonic acid (R)-4,4-dimethyl-2-oxo-tetrahydro-furan-3-yl ester

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 94 percent / 18-crown-6 / benzene / 3 h / Heating
2: 5percent KOH / methanol / Heating
View Scheme
(R)-Pantolacton
599-04-2

(R)-Pantolacton

taurine-p-toluidide

taurine-p-toluidide

pantolactone
79-50-5

pantolactone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 98 percent / pyridine / 0.17 h / 0 - 20 °C
2: 94 percent / 18-crown-6 / benzene / 3 h / Heating
3: 5percent KOH / methanol / Heating
View Scheme
Multi-step reaction with 3 steps
1: 88 percent / pyridine / 0.17 h / 0 - 20 °C
2: 38 percent / 18-crown-6 / benzene / 48 h / Heating
3: 5percent KOH / methanol / Heating
View Scheme
1-Heptylamine
111-68-2

1-Heptylamine

pantolactone
79-50-5

pantolactone

N-heptyl-2,4-dihydroxy-3,3-dimethylbutyramide
43180-77-4

N-heptyl-2,4-dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
In methanol at 20℃; for 20h;100%
at 100 - 110℃;
at 100 - 110℃;
diethylamine
109-89-7

diethylamine

pantolactone
79-50-5

pantolactone

N,N-Diethyl-2,4-dihydroxy-3,3-dimethyl-butyramide

N,N-Diethyl-2,4-dihydroxy-3,3-dimethyl-butyramide

Conditions
ConditionsYield
In acetonitrile at 30℃; under 6750540 Torr; for 168h;100%
methylamine
74-89-5

methylamine

pantolactone
79-50-5

pantolactone

β,β-dimethyl-α,γ-dihydroxybutyric acid N-methylamide
79691-41-1

β,β-dimethyl-α,γ-dihydroxybutyric acid N-methylamide

Conditions
ConditionsYield
In methanol; water at 20℃; for 3h;100%
In water Ring cleavage;
benzylamine
100-46-9

benzylamine

pantolactone
79-50-5

pantolactone

N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide
100618-94-8

N-benzyl-2,4-dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
In methanol at 20℃; for 24h;100%
In methanol for 3h; Ambient temperature;93%
pantolactone
79-50-5

pantolactone

(R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide
4417-86-1

(R,S)-2,4-Dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
With ammonia at -60 - 20℃; Ring cleavage;100%
With ammonium hydroxide In methanol at 20℃; for 14h;84%
Multi-step reaction with 3 steps
1: 100 percent / methanol / 24 h / 20 °C
2: 14 percent Spectr. / p-TsOH*H2O / bis-(2-methoxy-ethyl) ether / 5 h / Heating
3: 84 percent / aq. NH3 / methanol / 14 h / 20 °C
View Scheme
2-Methoxyethoxymethyl chloride
3970-21-6

2-Methoxyethoxymethyl chloride

pantolactone
79-50-5

pantolactone

4,4-dimethyl-2-methoxyethoxymethoxy-γ-butyrolactone
915097-01-7

4,4-dimethyl-2-methoxyethoxymethoxy-γ-butyrolactone

Conditions
ConditionsYield
With 15-crown-5; sodium hydride In tetrahydrofuran at 22℃; for 15h;100%
pantolactone
79-50-5

pantolactone

ketopantolactone
13031-04-4

ketopantolactone

Conditions
ConditionsYield
With oxygen In 1,2-dichloro-benzene at 180℃; for 3h;99.5%
With trichloroisocyanuric acid; tetrabutylammomium bromide; water; potassium carbonate; ruthenium trichloride In acetonitrile at 20 - 45℃; for 1 - 3h; Product distribution / selectivity;97.7%
With ruthenium(III) chloride trihydrate; trichloroisocyanuric acid; tetrabutylammomium bromide; sodium acetate In water; acetonitrile at 25 - 45℃; Green chemistry; chemoselective reaction;97.7%
pantolactone
79-50-5

pantolactone

potassium pantoate

potassium pantoate

Conditions
ConditionsYield
With water; potassium hydroxide at 60℃; for 4h;99.2%
triethylmethoxystannane
1067-21-6

triethylmethoxystannane

pantolactone
79-50-5

pantolactone

DL-2-triethylstannoxy-3,3-dimethyl-γ-butyrolactone
56150-63-1

DL-2-triethylstannoxy-3,3-dimethyl-γ-butyrolactone

Conditions
ConditionsYield
In neat (no solvent) byproducts: MeOH; mixt. of the hydroxy deriv. and triethylmethoxystannane heated (formed MeOH removed continuously during react.); distn.; elem. anal.;99%
benzyl bromide
100-39-0

benzyl bromide

pantolactone
79-50-5

pantolactone

3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one
117895-47-3

3-(benzyloxy)-4,4-dimethyldihydrofuran-2(3H)-one

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide; silver(l) oxide In dichloromethane at 20℃; for 48h; Darkness;98%
pantolactone
79-50-5

pantolactone

DL-sodium pantoate
1902-01-8

DL-sodium pantoate

Conditions
ConditionsYield
With water; sodium hydroxide at 60℃; for 4h;96.3%
With sodium hydroxide In ethanol for 2h; Yield given;
chloromethyl methyl ether
107-30-2

chloromethyl methyl ether

pantolactone
79-50-5

pantolactone

3,3-dimethyl-2-methoxymethoxy-4-butanolide
90113-81-8

3,3-dimethyl-2-methoxymethoxy-4-butanolide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In 1,2-dichloro-ethane at 40℃; for 24h;96%
1-amino-3-(dimethylamino)propane
109-55-7

1-amino-3-(dimethylamino)propane

pantolactone
79-50-5

pantolactone

N-[3-(dimethylamino)propyl]-2,4-dihydroxy-3,3-dimethylbutyramide

N-[3-(dimethylamino)propyl]-2,4-dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
In 1,4-dioxane for 5h; Heating;96%
1-hydroxygermatrane monohydrate
101151-96-6

1-hydroxygermatrane monohydrate

pantolactone
79-50-5

pantolactone

DL-2-germatranoxy-3,3-dimethyl-γ-butyrolactone
133517-05-2

DL-2-germatranoxy-3,3-dimethyl-γ-butyrolactone

Conditions
ConditionsYield
In m-xylene=m-xylol byproducts: H2O; mixt. of the germatrane with the hydroxy compd. in m-xylene refluxed with azeotropic distn. of H2O; residue filtered off, washed with n-pentane, recrystn. from CH3CN; elem. anal.;96%
(1R,2R,3S,4S)-3-Amino-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol
29900-93-4

(1R,2R,3S,4S)-3-Amino-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol

pantolactone
79-50-5

pantolactone

2,4-dihydroxy-N-<(1R)-2-endo-hydroxy-3-endo-bornyl>-3,3-dimethylbutyramide

2,4-dihydroxy-N-<(1R)-2-endo-hydroxy-3-endo-bornyl>-3,3-dimethylbutyramide

Conditions
ConditionsYield
In toluene at 110℃; for 1.5h;95.7%
ethylamine
75-04-7

ethylamine

pantolactone
79-50-5

pantolactone

N-ethyl-2,4-dihydroxy-3,3-dimethylbutyramide
4417-90-7

N-ethyl-2,4-dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
In methanol for 3h; Ambient temperature;95%
at 100℃;
aniline
62-53-3

aniline

pantolactone
79-50-5

pantolactone

rac-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone
70006-37-0

rac-3-hydroxy-4,4-dimethyl-1-phenyl-2-pyrrolidinone

Conditions
ConditionsYield
With toluene-4-sulfonic acid In methanol at 250℃; under 7220 - 11400 Torr; for 4h; Heating;93%
82%
methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

pantolactone
79-50-5

pantolactone

4,4-dimethyl-2-oxotetrahydro-3-furyl methane sulfonate
20664-78-2

4,4-dimethyl-2-oxotetrahydro-3-furyl methane sulfonate

Conditions
ConditionsYield
With triethylamine In dichloromethane at -5℃;92%
2,3-dihydro-2H-furan
1191-99-7

2,3-dihydro-2H-furan

pantolactone
79-50-5

pantolactone

3,3-dimethyl-2-(2-tetrahydrofuryloxy)-4-butanolide
371198-80-0

3,3-dimethyl-2-(2-tetrahydrofuryloxy)-4-butanolide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In dichloromethane at 0℃;91%
cyclohexylamine
108-91-8

cyclohexylamine

pantolactone
79-50-5

pantolactone

N-cyclohexyl-2,4-dihydroxy-3,3-dimethylbutyramide
16424-76-3

N-cyclohexyl-2,4-dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
In methanol for 3h; Ambient temperature;90%
N-butylamine
109-73-9

N-butylamine

pantolactone
79-50-5

pantolactone

N-butyl-2,4-dihydroxy-3,3-dimethylbutyramide
43180-76-3

N-butyl-2,4-dihydroxy-3,3-dimethylbutyramide

Conditions
ConditionsYield
In methanol for 3h; Ambient temperature;89%
at 100 - 110℃;
at 100 - 110℃;
propionic acid anhydride
123-62-6

propionic acid anhydride

pantolactone
79-50-5

pantolactone

(+/-)-pantolactone propionate

(+/-)-pantolactone propionate

Conditions
ConditionsYield
With 4-pyrrolidin-1-ylpyridine; triethylamine In dichloromethane for 10h; Ambient temperature;89%
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