Dimethyl acetylenedicarboxylate supplier

Name
Dimethyl acetylenedicarboxylate
EINECS 212-098-4
CAS No. 762-42-5
Article Data40
CAS DataBase
Density 1.206 g/cm³
Solubility Soluble in most organic solvents. Insoluble in water.
Melting Point -18 °C
Formula C₆H₆O₄
Boiling Point 204.309 °C at 760 mmHg
Molecular Weight 142.111
Flash Point 86.111 °C
Transport Information UN 3265 8/PG 2
Appearance clear colorless to light yellow liquid
Safety 23-26-27-36/37/39-45
Risk Codes 34-22
Molecular Structure
Hazard Symbols C
Synonyms Dimethyl acetylenedicarboxylic acid;1,2-Bis(methoxycarbonyl)acetylene;Dimethyl ethynedicarboxylate;Di(carbomethoxy)acetylene;Dimethyl butynedioate;2-Butynedioic acid, dimethyl ester;Bis(methoxycarbonyl)acetylene;dimethyl but-2-ynedioate;Dimethyl but-2-yndioate;But-2-ynedioic acid dimethyl ester;Dimethyl 2-butynedioate;1, 2-Bis(methoxycarbonyl)acetylene;Methyl acetylenedicarboxylate;Acetylenedicarboxylic acid, dimethyl ester;1,2-Bis(methoxycarbonyl)ethyne;Acetylenedicarboxylic acid dimethyl ester;Acetylenedicarboxylic acid, dimethyl ester (8CI);
PSA 52.60000
LogP -0.66420

Synthetic route

: 67-56-1
methanol

: 142-45-0
Acetylenedicarboxylic acid

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In 1,2-dichloro-ethane; toluene Reflux;	93%
With sulfuric acid at 20℃; for 24h; Inert atmosphere;	88%
With sulfuric acid
With toluene-4-sulfonic acid

: 1114-20-1, 62675-22-3, 116631-94-8
trans-2,3-dibromobutenedioic acid dimethyl ester

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With zinc In tetrahydrofuran for 2h; Heating;	93%
With zinc In tetrahydrofuran for 2h; Heating; Yield given;

: (C5H5)2VC2(CO2CH3)2

A: 12083-48-6
bis(cyclopentadienyl)vanadium dichloride

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With chlorine In tetrachloromethane	A 68% B 37%
With Cl2 In tetrachloromethane	A 68% B 37%

: 86625-25-4
3-methoxycarbonyl-5-pyrazolinone

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene In methanol 1.) -23 deg C, 45 min; 2.) rt, 1 h;	59%

: 64995-84-2
dimethyl 2-oxo-3-triphenylphosphoranylidenebutanedioate

A: 762-42-5
dimethyl acetylenedicarboxylate

B: 791-28-6
Triphenylphosphine oxide

Conditions

Conditions	Yield
at 500℃; under 0.01 Torr;	A 59% B n/a
at 500℃; under 0.001 - 0.1 Torr; for 1h;	A 59 % Spectr. B n/a

: 68827-52-1
methyl 7-oxo-2-phenyl-7H-[1,2,4]triazolo[3,2-b][1,3]thiazine-5-carboxylate

: 67-56-1
methanol

A: 762-42-5
dimethyl acetylenedicarboxylate

B: 3414-94-6
3-phenyl-4,5-dihydro-1H-1,2,4-triazole-5-thione

Conditions

Conditions	Yield
Stage #1: methyl 7-oxo-2-phenyl-7H-[1,2,4]triazolo[3,2-b][1,3]thiazine-5-carboxylate With potassium hydroxide In methanol; water for 48h; Stage #2: methanol at 20℃; for 96h;	A n/a B 59%

...Expand

: 183586-23-4
(Z)-1-hydroperoxy-N-[(Z)-3-(methoxycarbonyl)-2-propenylidene]cyclohexylamine N-oxide

A: 57314-32-6
Maleinaldehydsaeure-methylester

B: 108-94-1
cyclohexanone

C: 762-42-5
dimethyl acetylenedicarboxylate

D: 183813-49-2
(Z)-4-[(E)-Hydroxyimino]-but-2-enoic acid methyl ester

Conditions

Conditions	Yield
In benzene for 0.5h; Heating; Further byproducts given;	A 32% B 6% C 32% D n/a

...Expand

: 183586-23-4
(Z)-1-hydroperoxy-N-[(Z)-3-(methoxycarbonyl)-2-propenylidene]cyclohexylamine N-oxide

A: 108-94-1
cyclohexanone

B: 762-42-5
dimethyl acetylenedicarboxylate

C: 183586-28-9
(Z)-anti-methyl 4-(hydroxyimino)but-2-enoate

D: 183813-49-2
(Z)-4-[(E)-Hydroxyimino]-but-2-enoic acid methyl ester

Conditions

Conditions	Yield
In benzene for 0.5h; Heating; Further byproducts given. Title compound not separated from byproducts;	A 6% B 32% C n/a D n/a

...Expand

: 58150-95-1
(1S,3aR)-1H-1,3a-Etheno-azulene-9,10-dicarboxylic acid dimethyl ester

A: 58150-88-2
dimethyl heptalene-4,5-dicarboxylate

B: 762-42-5
dimethyl acetylenedicarboxylate

C: 275-51-4
azulene

Conditions

Conditions	Yield
In (2)H8-toluene at 60℃; under 750.06 Torr; for 30h; thermolyse, other pressure;

...Expand

: 116935-20-7
2-(2-thienyl)-4,5-dimethoxycarbonyl-1,3-dithiole

: 74-88-4
methyl iodide

A: 2168-83-4
thiophene-2-carbodithioic acid methyl ester

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With n-butyllithium 1) 2 h -30 deg C THF hexane, 2) 2 h; Multistep reaction;

...Expand

: Bicyclo[2.2.2]octa-2,5,7-triene-2,3,5,6-tetracarboxylic acid tetramethyl ester

A: 131-11-3
phthalic acid dimethyl ester

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With base

: 67-56-1
methanol

: 608-37-7
dibromomaleic acid

A: 762-42-5
dimethyl acetylenedicarboxylate

B: 624-49-7
dimethylfumarate

C: 106-65-0
Dimethyl succinate

Conditions

Conditions	Yield
With samarium; sulfuric acid 1) MeOH, 24 h, RT, 2) reflux; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 67-56-1
methanol

: 916065-46-8
meso-2,3-dibromosuccinic acid

A: 762-42-5
dimethyl acetylenedicarboxylate

B: 624-49-7
dimethylfumarate

C: 106-65-0
Dimethyl succinate

Conditions

Conditions	Yield
With samarium; sulfuric acid 1) MeOH, 24 h, Rt, 2) reflux; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

: 194220-96-7
Dimethyl 1-(2-chlorophenyl)-7-oxabicyclo[2.2.1]heptadiene-2,3-dicarboxylate

A: 38527-56-9
2-(2-chlorophenyl)furan

B: 762-42-5
dimethyl acetylenedicarboxylate

C: 2'-Chloro-4-hydroxy-biphenyl-2,3-dicarboxylic acid dimethyl ester

D: 5-[1-(2-Chloro-phenyl)-1-hydroxy-meth-(Z)-ylidene]-cyclopenta-1,3-diene-1,2-dicarboxylic acid dimethyl ester

Conditions

Conditions	Yield
With hydrogenchloride; water In dichloromethane for 24h; Product distribution; Further Variations:; Reagents; Solvents; Temperatures; retro-Diels-Alder reaction; Heating;

...Expand

: 67-56-1
methanol

monopotassium salt of/the/ acetylenedicarboxylic acid: monopotassium salt of/the/ acetylenedicarboxylic acid

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With sulfuric acid at 25℃;
With sulfuric acid

: 67-56-1
methanol

monopotassium-salt of/the/ butynedioic acid: monopotassium-salt of/the/ butynedioic acid

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With sulfuric acid; sulfur trioxide; 1,2-dichloro-ethane

: 67-56-1
methanol

: 7664-93-9
sulfuric acid

: 142-45-0
Acetylenedicarboxylic acid

A: 2215-12-5
2-methoxyfumaric acid

B: 26579-97-5
2-methoxy-2-butenedioic acid dimethyl ester

C: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
Veresterung;

...Expand

: 121619-92-9
tetrakis(2-bromobenzoato)bis(dimethyl acetylenedicarboxylate)tetracopper(I)

A: tetrakis(2-bromobenzoato)(dimethyl acetylenedicarboxylate)tetracopper(I)

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
In (2)H8-toluene N2, NMR tube, T: 213 - 293 K; (1)H NMR spectroscopy;

: 121619-91-8
tetrakis(2-chlorobenzoato)bis(dimethyl acetylenedicarboxylate)tetracopper(I)

A: tetrakis(2-chlorobenzoato)(dimethyl acetylenedicarboxylate)tetracopper(I)

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
In (2)H8-toluene N2, NMR tube, T: 213 - 293 K; (1)H NMR spectroscopy;

: 121619-90-7
tetrakisbenzoatobis(dimethyl acetylenedicarboxylate)tetracopper(I)

A: tetrakisbenzoato(dimethyl acetylenedicarboxylate)tetracopper(I)

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
In (2)H8-toluene N2, NMR tube, T: 213 - 298 K; (1)H NMR spectroscopy;

: 1,1,2-tricarbonyl-μ-(dimethyl 2-butynedioate-μ-C(2),μ-C(3)3)(2-3-η-dimethyl 2-butynedioate)-μ-(1-5:1'-5'-.eta-fulvalene)-dimolybdenum (Mo-Mo)

A: (η5:η5-fulvalene)tetracarbonyl(dimethyl ethynedicarboxylate)dimolybdenum

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
In toluene heating in toluene at 110°C; alkyne detected by NMR;

: 77590-29-5
Pd2((C6H5)4P2CH2)2C2(CO2CH3)2I2

A: 67477-87-6
Pd2I2(μ-bis(diphenylphosphino)methane)2

B: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
In dichloromethane Irradiation (UV/VIS); Exposure of a CH2Cl2-soln. to light from Hg lamp;;

: 1,3-bis(azidopropyl)tetramethyldisiloxane

: 762-42-5
dimethyl acetylenedicarboxylate

: 18434-84-9
dimethyl (2E)-2,3-diiodo-2-butenedioate

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide In nitrobenzene-d5 at 45℃; for 40h; Inert atmosphere; Darkness;

: 51575-86-1
dimethyl 2,3-dibromobutane-1,4-dicarboxylate

: 762-42-5
dimethyl acetylenedicarboxylate

Conditions

Conditions	Yield
With potassium hydroxide In ethanol for 4h; Time; Reflux;

: 96-54-8
N-Methylpyrrole

: 762-42-5
dimethyl acetylenedicarboxylate

: 1444-11-7
1-methyl-1,7a-dihydro-indole-2,3,3a,4-tetracarboxylic acid tetramethyl ester

Conditions

Conditions	Yield
In dichloromethane at 40℃; under 11250900 Torr; for 6h;	100%

: 762-42-5
dimethyl acetylenedicarboxylate

: 6237-59-8
hexamethyl benzenehexacarboxylate

Conditions

Conditions	Yield
[Rh(CO)Cl(1,2-bis(diphenylphosphino)ethane)] In tetrahydrofuran-d8 at 65℃; for 1h; cyclotrimerization;	100%
With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; (R)-(+)-2,2'-bis(diphenylphosphanyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl In dichloromethane at 20℃; for 1h;	100%
Rh[C60(PhCH2)2Ph](cod) In 1,2-dichloro-benzene at 60℃; for 24h;	99%

: 110-91-8
morpholine

: 762-42-5
dimethyl acetylenedicarboxylate

: 24432-42-6
dimethyl (Z)-2-(morpholino)-2-butenedioate

Conditions

Conditions	Yield
at 20℃; for 0.05h; Michael addition;	100%
at 100℃; for 3h;
With water; potassium carbonate at 20℃; stereoselective reaction;

: 106-49-0
p-toluidine

: 762-42-5
dimethyl acetylenedicarboxylate

: 24559-80-6
dimethyl (Z)-N-(4-methylphenyl)aminofumarate

Conditions

Conditions	Yield
at 20℃; for 0.133333h; Michael addition;	100%
In benzene at 5 - 10℃;	70%
In diethyl ether

: 109-89-7
diethylamine

: 762-42-5
dimethyl acetylenedicarboxylate

: 996-85-0
dimethyl (2E)-2-(diethylamino)but-2-enedioate

Conditions

Conditions	Yield
In water at 20℃; for 2h; Michael-type addition;	100%
In diethyl ether

: 95-55-6
2-amino-phenol

: 762-42-5
dimethyl acetylenedicarboxylate

: 66628-73-7
(2Z)-[2-oxo-2H-1,4-benzoxazine-3(4H)-ylidene]acetic acid methyl ester

Conditions

Conditions	Yield
at 20℃; for 0.0666667h; Michael addition;	100%
In neat (no solvent) at 20℃; for 0.166667h; regioselective reaction;	98%
In ethanol at 0℃; for 3h;	94%

: 107-10-8
propylamine

: 762-42-5
dimethyl acetylenedicarboxylate

: 24559-78-2
dimethyl (Z)-2-(n-propylamino)fumarate

Conditions

Conditions	Yield
at 20℃; for 0.05h; Michael addition;	100%
In diethyl ether

: 762-42-5
dimethyl acetylenedicarboxylate

: 100-61-8
N-methylaniline

: 125735-97-9
2-(methylphenylamino)but-2-enedioic acid dimethyl ester

Conditions

Conditions	Yield
In water at 20℃; for 2h; Michael-type addition;	100%
In water at 20℃;	71%
In water at 0 - 20℃; for 2h;	69%
In diethyl ether

: 110-89-4
piperidine

: 762-42-5
dimethyl acetylenedicarboxylate

: 4596-77-4
1,4-dimethyl (2E)-2-(piperidin-1-yl)but-2-enedioate

Conditions

Conditions	Yield
In water at 20℃; for 2h; Michael-type addition;	100%
With silica gel for 0.0833333h; Neat (no solvent); optical yield given as %de; chemoselective reaction;	82%
In 1,4-dioxane at 80℃; for 10h;	60%
In diethyl ether
In diethyl ether at 0℃;

: 110-91-8
morpholine

: 762-42-5
dimethyl acetylenedicarboxylate

: 26138-59-0
dimethyl α-morpholinomaleate

Conditions

Conditions	Yield
In water at 20℃; for 2h; Michael-type addition;	100%
In diethyl ether for 24h; Ambient temperature;	86%
With silica gel for 0.0833333h; Neat (no solvent); optical yield given as %de; chemoselective reaction;	84%
In diethyl ether for 15h; Ambient temperature;	70%

: 625-86-5
2,5-dimethylfuran

: 762-42-5
dimethyl acetylenedicarboxylate

: 18063-93-9
dimethyl 1,4-dimethyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

Conditions

Conditions	Yield
In 1,4-dioxane at 103℃;	100%
In dichloromethane under 7500600 Torr; for 20h; Ambient temperature;	95%
In 1,4-dioxane at 101℃; for 17.5h;	81%

: 625-86-5
2,5-dimethylfuran

: 762-42-5
dimethyl acetylenedicarboxylate

: 18063-93-9
dimethyl 1,4-dimethyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate

Conditions

Conditions	Yield
at 100℃; for 21h;	100%
at 100℃; for 2h; Sealed tube;	78%
In 1,4-dioxane at 100℃; for 24h; Diels-Alder reaction;
In toluene at 150℃; Diels-Alder reaction; Microwave irradiation;

: (E)-2H-chromen-2-one oxime

: 762-42-5
dimethyl acetylenedicarboxylate

: dimethyl (2H-<1>benzopyran-2-ylidenaminoxy)butenedioate

Conditions

Conditions	Yield
With triethylamine In dichloromethane Ambient temperature;	100%

: 6476-40-0
1-methyl-cis-2-benzoyl-3-phenylaziridine

: 762-42-5
dimethyl acetylenedicarboxylate

: 113405-17-7
(E)-2-[((E)-1-Benzoyl-2-phenyl-vinyl)-methyl-amino]-but-2-enedioic acid dimethyl ester

Conditions

Conditions	Yield
for 24h; Ambient temperature;	100%

: 2835-98-5
2-Hydroxy-4-methylanilin

: 762-42-5
dimethyl acetylenedicarboxylate

: 104827-36-3
(Z)-3-methoxycarbonylmethylene-7-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-one

Conditions

Conditions	Yield
at 20℃; for 0.0333333h; Michael addition;	100%
In ethanol at 0℃; for 3h;	92%
In methanol Ambient temperature;	88.89%

: 95-54-5
1,2-diamino-benzene

: 762-42-5
dimethyl acetylenedicarboxylate

: 53700-46-2
(Z)-methyl 2-(3-oxo-3,4-dihydroquinoxalin-2(1H)-ylidene)acetate

Conditions

Conditions	Yield
at 20℃; for 0.0166667h; Michael addition;	100%
for 0.0833333h; microwave irradiation;	90%
In methanol Heating;
at 20℃; for 0.0833333h; Milling;

: 95-84-1
3-amino-4-hydroxytoluene

: 762-42-5
dimethyl acetylenedicarboxylate

: 70917-48-5
(Z)-3-methoxycarbonylmethylene-6-methyl-3,4-dihydro-2H-1,4-benzoxazin-2-one

Conditions

Conditions	Yield
at 20℃; for 0.0333333h; Michael addition;	100%
In ethanol at 0℃; for 3h;	93%
In methanol Ambient temperature;	92.27%

: 922-69-0
1,1-dimethoxyethylene

: 762-42-5
dimethyl acetylenedicarboxylate

: 142645-55-4
dimethyl 3,3-dimethoxycyclobutene-1,2-dicarboxylate

Conditions

Conditions	Yield
In chloroform at 18℃; for 3h;	100%
In toluene at 28 - 32℃; for 15h;	93%
In acetonitrile at 18 - 22℃; for 3h;	53%

: 74-90-8
hydrogen cyanide

: 762-42-5
dimethyl acetylenedicarboxylate

: 6237-59-8
hexamethyl benzenehexacarboxylate

Conditions

Conditions	Yield
With triphenyl phosphite; tetrakis(triphenylphosphite)nickel(0); zinc(II) chloride In toluene at 60℃; for 0.5h;	100%

: 5634-52-6
1,1-dimethoxy-propene

: 762-42-5
dimethyl acetylenedicarboxylate

: 142645-56-5
3,3-Dimethoxy-4-methyl-cyclobut-1-ene-1,2-dicarboxylic acid dimethyl ester

Conditions

Conditions	Yield
In chloroform at 18℃; for 3h;	100%
In acetonitrile at 18 - 22℃; for 3h; Product distribution; Mechanism; other solvents, other temperatures, other times, other acetylenic ester; other 1,1-dimethoxyalkenes;	58%
In acetonitrile at 18 - 22℃; for 3h;	58%

: 99115-93-2
1,1-dimethoxy-but-1-ene

: 762-42-5
dimethyl acetylenedicarboxylate

: 4-Ethyl-3,3-dimethoxy-cyclobut-1-ene-1,2-dicarboxylic acid dimethyl ester

Conditions

Conditions	Yield
In chloroform at 18℃; for 3h;	100%

: 29634-51-3
tris(methylseleno)borane

: 762-42-5
dimethyl acetylenedicarboxylate

A: 132330-33-7
(Z)-2-Methylselanyl-but-2-enedioic acid dimethyl ester

B: 82849-75-0
(E)-2,3-Bis-methylselanyl-but-2-enedioic acid dimethyl ester

Conditions

Conditions	Yield
In dichloromethane for 0.5h; Ambient temperature;	A 100% B n/a
In dichloromethane for 0.5h; Ambient temperature; Yields of byproduct given;	A 75% B n/a

...Expand

: 29680-62-4
Tris(phenylseleno)borane

: 762-42-5
dimethyl acetylenedicarboxylate

: 15642-80-5
Phenylselenoethylendicarbonsaeure-dimethylester

Conditions

Conditions	Yield
In dichloromethane for 0.5h; Ambient temperature;	100%

: 2446-52-8
ethyl N-hydroxyiminobenzoate

: 762-42-5
dimethyl acetylenedicarboxylate

: 139172-68-2
ethyl O-(2'-ethoxycarbonylvinyl)-N-hydroxyiminobenzoate

Conditions

Conditions	Yield
With triethylamine In dichloromethane Ambient temperature;	100%

: 30907-73-4
2-(methylamino)-N'-(2-phenylacetyl)benzohydrazide

: 762-42-5
dimethyl acetylenedicarboxylate

: 2-Methoxycarbonylmethyl-1-methyl-4-oxo-3-phenylacetylamino-1,2,3,4-tetrahydro-quinazoline-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
In methanol for 2h; Heating;	100%

: 124944-28-1
<4.3.2>Propella-2,4,8-trien-7-one

: 762-42-5
dimethyl acetylenedicarboxylate

: C17H16O5

Conditions

Conditions	Yield
at 80℃; for 12h;	100%

: 89241-38-3
1,3-dimethyl-4-(phenylsulfonyl)-4H-furo[3,4-b]indole

: 762-42-5
dimethyl acetylenedicarboxylate

: 92399-38-7
Dimethyl 1,4-Epoxy-1,4-dimethyl-1,4-dihydro-5-(phenylsulfonyl)-2,3-carbazoledicarboxylate

Conditions

Conditions	Yield
In benzene 1.) 1h, room temp., 2.) 5h, reflux;	100%

: 116375-45-2
3,4-di-tert-butyl-thiophene 1,1-dioxide

: 762-42-5
dimethyl acetylenedicarboxylate

: 116375-46-3
4,5-Di-tert-butyl-phthalic acid dimethyl ester

Conditions

Conditions	Yield
In 1,2-dichloro-benzene for 7h; Heating;	100%

: 4473-99-8
<4.3.2>propella-2,4,7,10-tetraene

: 762-42-5
dimethyl acetylenedicarboxylate

: 131236-31-2
C17H16O4

Conditions

Conditions	Yield
at 70℃; for 3h;	100%

: 130935-28-3
N-(diazoacetoacetyl)-N-phenyl-1-pyrrolidinecarboxamide

: 762-42-5
dimethyl acetylenedicarboxylate

: 130935-29-4
dimethyl 2-acetyl-5-pyrrolidine-3,4-furandicarboxylate

Conditions

Conditions	Yield
rhodium(II) octanoate In benzene at 25℃; for 0.25h;	100%

Dimethyl acetylenedicarboxylate Chemical Properties

IUPAC Name: Dimethyl but-2-ynedioate
Molecular Formula: C₆H₆O₄
Molecular Weight: 142.11 g/mol
Canonical SMILES: C(C(OC)=O)#CC(OC)=O
InChI: InChI=1/C6H6O4/c1-9-5(7)3-4-6(8)10-2/h1-2H3
EINECS: 212-098-4
Classification Code: Agricultural Chemical; Experimental pesticide; Unspecified / Unclassified pesticide
Product Categories: Aromatic Esters;Small molecule; Acetylenes; Acetylenic Carboxylic Acids & Their Derivatives
Sensitive: Light Sensitive
Surface Tension: 41.1 dyne/cm
Density: 1.205 g/cm³
Flash Point: 86.1 °C
Enthalpy of Vaporization: 44.05 kJ/mol
Boiling Point: 204.3 °C at 760 mmHg
Melting Point: -18 °C
Vapour Pressure of Dimethyl acetylenedicarboxylate (CAS NO.762-42-5): 0.265 mmHg at 25 °C

Dimethyl acetylenedicarboxylate Uses

Dimethyl acetylenedicarboxylate (CAS NO.762-42-5) is mainly used in organic synthesis. It is is a lachrymator and a vesicant.

Dimethyl acetylenedicarboxylate Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	550mg/kg (550mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: COMA	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 28(6), Pg. 55, 1984.
rat	LDLo	oral	50mg/kg (50mg/kg)		National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 13, 1953.

Dimethyl acetylenedicarboxylate Consensus Reports

Reported in EPA TSCA Inventory.

Dimethyl acetylenedicarboxylate Safety Profile

Poison by ingestion. A dienophile. Explosive reaction with 1-methylsilacyclopenta-2,4-diene at 150°C. Octakis(trifluorophosphine)dirhodium catalyzes explosive polymerization of the acid above 20°C. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes: Corrosive C
Risk Statements: 34-22
R34: Causes burns.
R22: Harmful if swallowed.
Safety Statements: 23-26-27-36/37/39-45
S23: Do not breathe vapour.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27: Take off immediately all contaminated clothing.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3265 8/PG 2
WGK Germany: 3
RTECS: ES0175000
F: 8-19
HazardClass: 8
PackingGroup of Dimethyl acetylenedicarboxylate (CAS NO.762-42-5): III

Dimethyl acetylenedicarboxylate Specification

Dimethyl acetylenedicarboxylate (CAS NO.762-42-5), its Synonyms are Acetylenedicarboxylic acid dimethyl ester ; 2-Butynedioic acid, 1,4-dimethyl ester ; 2-Butynedioic acid, dimethyl ester ; 1,2-Bis(methoxycarbonyl)acetylene ; Bis(methoxycarbonyl)acetylene . It is clear colorless to light yellow liquid.

Product Name

Dimethyl acetylenedicarboxylate

Synthetic route

Dimethyl acetylenedicarboxylate Chemical Properties

Dimethyl acetylenedicarboxylate Uses

Dimethyl acetylenedicarboxylate Toxicity Data With Reference

Dimethyl acetylenedicarboxylate Consensus Reports

Dimethyl acetylenedicarboxylate Safety Profile

Dimethyl acetylenedicarboxylate Specification

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