Product Name

  • Name

    Hexobarbital sodium

  • EINECS
  • CAS No. 50-09-9
  • Density
  • Solubility
  • Melting Point
  • Formula C12H15N2O3•Na
  • Boiling Point 368.8°C at 760 mmHg
  • Molecular Weight 258.252
  • Flash Point 176.8°C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal, parenteral, and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Used intravenously as a general anesthetic. When heated to decomposition it emits toxic fumes of NOx and Na2O. See also EVIPAL and BARBITURATES.
  • Risk Codes
  • Molecular Structure Molecular Structure of 50-09-9 (Hexobarbital sodium)
  • Hazard Symbols
  • Synonyms
  • PSA
  • LogP

Evipal sodium Chemical Properties

IUPAC Name: Sodium 5-cyclohexen-1-yl-1,5-dimethylpyrimidin-3-ide-2,4,6-trione
Synonyms of Evipal sodium (CAS NO.50-09-9) : 1,5-Dimethyl-5-cyclohexenyl-1'-barbituric acid, sodium salt ; 5-(1-Cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione monosodium salt ; Cyclohexenylmethyl-N-methyl barbituric acid sodium salt ; Cyclonal sodium ; Hexenal sodium ; Methexenyl sodium ; Sodium 5-(1-cyclohexen-1-yl)-1,5-dimethylbarbiturate ; Sodium methylhexabitol ; Sombulex 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-, sodium salt ; Barbituric acid, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-, sodium salt
CAS NO:50-09-9
Molecular Formula:C12H15N2NaO3
Molecular Weight :258.2568
Molecular Structure :
EINECS: 200-009-1
Flash Point: 176.8 °C
Enthalpy of Vaporization: 71.22 kJ/mol
Boiling Point: 368.8 °C at 760 mmHg
Vapour Pressure: 6.12E-07 mmHg at 25°C

Evipal sodium Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 85mg/kg (85mg/kg) BEHAVIORAL: GENERAL ANESTHETIC Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 125, 1937.
dog LDLo subcutaneous 107mg/kg (107mg/kg) BEHAVIORAL: SLEEP Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 323, 1937.
frog LDLo parenteral 30mg/kg (30mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 50, Pg. 347, 1934.
guinea pig LDLo intraperitoneal 100mg/kg (100mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

BEHAVIORAL: COMA		 Journal of Pharmacology and Experimental Therapeutics. Vol. 50, Pg. 347, 1934.
mouse LD50 intraperitoneal 240mg/kg (240mg/kg)   Acta Biologica et Medica Germanica. Vol. 6, Pg. 407, 1961.
mouse LD50 intravenous 165mg/kg (165mg/kg)   Toxicology and Applied Pharmacology. Vol. 23, Pg. 537, 1972.
mouse LD50 oral 1325mg/kg (1325mg/kg)   Toxicology and Applied Pharmacology. Vol. 27, Pg. 70, 1974.
mouse LD50 subcutaneous 410mg/kg (410mg/kg)   Toxicology and Applied Pharmacology. Vol. 27, Pg. 70, 1974.
rabbit LD50 intravenous 72mg/kg (72mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 265, 1946.
rabbit LDLo intraperitoneal 150mg/kg (150mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 54, Pg. 77, 1935.
rat LCLo inhalation 2000ppm/4H (2000ppm)   AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 10, Pg. 61, 1954.
rat LD50 intraperitoneal 375mg/kg (375mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 21, Pg. 109, 1969.
rat LD50 oral 1gm/kg (1000mg/kg)   Archives of Toxicology. Vol. 54, Pg. 275, 1983.
rat LDLo subcutaneous 363mg/kg (363mg/kg) BEHAVIORAL: SLEEP Journal of Pharmacology and Experimental Therapeutics. Vol. 60, Pg. 323, 1937.

Evipal sodium Safety Profile

Poison by intraperitoneal, parenteral, and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Used intravenously as a general anesthetic. When Evipal sodium (CAS NO.50-09-9) is heated to decomposition ,it emits toxic fumes of NOx and Na2O. See also EVIPAL and BARBITURATES.

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

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