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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

3-Fluorophenylacetonitrile Manufacturer/High quality/Best price/In stock

Cas:501-00-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 501-00-8 with fast shipping

Cas:501-00-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name 3-Fluorophenylacetonitrile Synonyms 3-Fluorobenzeneacetonitrile; 3-Fluorobenzyl cyanide Molecular Structure

3-Fluorophenylacetonitrile CAS: 501-00-8

Cas:501-00-8

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Liquid Storage:Store in sealed containers at cool & dry plac

high quality 3-Fluorophenylacetonitrile cas 501-00-8

Cas:501-00-8

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzeneacetonitrile,3-fluoro- 501-00-8

Cas:501-00-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Pharm Intermediates, 3-Fluorophenylacetonitrile CAS:501-00-8

Cas:501-00-8

Min.Order:1 Kilogram

FOB Price: $21.6 / 24.5

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Fluorophenylacetonitrile CAS:501-00-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

3-Fluorophenylacetonitrile CAS:501-00-8

Cas:501-00-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzeneacetonitrile,3-fluoro-

Cas:501-00-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzeneacetonitrile,3-fluoro-

Cas:501-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We have s

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Fluorobenzylcyanide

Cas:501-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 3-Fluorophenylacetonitrile CAS No.:501-00-8 Molecule Formula:C8H6FN Molecule Weight:135.14 Purity: 99.0% Package: 200kg/drum Description:Colorless transparent liquid Manufacture Standards:Enterprise Standard TESTING

High Quality 3-Fluorophenylacetonitrile in stock

Cas:501-00-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

3-Fluorobenzyl cyanide-

Cas:501-00-8

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 3-Fluorophenylacetonitrile Synonyms: Inter-fluorophenyl acetonitrile;3-fluoro-benzeneacetonitril;Acetonitrile, (m-fluorophenyl)-;m-Fluorobenzylcyanide;3-FLUOROBENZYL CYANIDE;3-FLUOROBENZENEACETONITRILE;3-FLUOROPHENYLACETONITRILE;M

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-Fluorophenylacetonitrile cas no. 501-00-8 98%

Cas:501-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

3-Fluorobenzyl cyanide

Cas:501-00-8

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3-Fluorophenylacetonitrile

Cas:501-00-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

potassium thioacyanate
333-20-0

potassium thioacyanate

4-methyl-N'-(3-fluorobenzylidene)benzenesulfonohydrazide
343229-18-5

4-methyl-N'-(3-fluorobenzylidene)benzenesulfonohydrazide

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

Conditions
ConditionsYield
With copper(l) iodide; oxygen; 1,8-diazabicyclo[5.4.0]undec-7-ene; toluene-4-sulfonic acid hydrazide In 1-methyl-pyrrolidin-2-one; acetonitrile at 80℃; under 760.051 Torr; for 7h; Molecular sieve; Green chemistry;65%
sodium cyanide
773837-37-9

sodium cyanide

1-(Bromomethyl)-3-fluorobenzene
456-41-7

1-(Bromomethyl)-3-fluorobenzene

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

Conditions
ConditionsYield
In dimethyl sulfoxide at 30℃;50%
In dimethyl sulfoxide at 30℃;50%
fluorobenzene
462-06-6

fluorobenzene

chloroacetonitrile
107-14-2

chloroacetonitrile

A

butanedinitrile
110-61-2

butanedinitrile

B

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

C

2-fluorophenyl acetonitrile
326-62-5

2-fluorophenyl acetonitrile

D

4-fluorophenylacetonitrile
459-22-3

4-fluorophenylacetonitrile

Conditions
ConditionsYield
In acetonitrile Product distribution; Mechanism; Irradiation; different concentration ratios;A 0.5%
B n/a
C n/a
D n/a
In acetonitrile for 22h; Kinetics; Product distribution; Mechanism; Irradiation;
sodium cyanide
143-33-9

sodium cyanide

1-(Bromomethyl)-3-fluorobenzene
456-41-7

1-(Bromomethyl)-3-fluorobenzene

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

sodium cyanide
143-33-9

sodium cyanide

m-fluorobenzyl chloride
456-42-8

m-fluorobenzyl chloride

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

phenylacetonitrile
140-29-4

phenylacetonitrile

A

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

B

2-fluorophenyl acetonitrile
326-62-5

2-fluorophenyl acetonitrile

C

4-fluorophenylacetonitrile
459-22-3

4-fluorophenylacetonitrile

D

α-(Fluorophenyl)acetonitrile
10036-43-8

α-(Fluorophenyl)acetonitrile

Conditions
ConditionsYield
With triethylamine tris(hydrogen fluoride) In sulfolane at 50℃; electrolysis; Further byproducts given. Yields of byproduct given;A n/a
B n/a
C n/a
D 48 % Chromat.
potassium cyanide
151-50-8

potassium cyanide

1-(Bromomethyl)-3-fluorobenzene
456-41-7

1-(Bromomethyl)-3-fluorobenzene

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

Conditions
ConditionsYield
In ethanol
ethanolic solution of 3-fluoro-benzyl bromide

ethanolic solution of 3-fluoro-benzyl bromide

aqueous sodium cyanide solution

aqueous sodium cyanide solution

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

m-Fluorotoluene
352-70-5

m-Fluorotoluene

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: benzene; bromine / Irradiation.UV-Licht
View Scheme
Multi-step reaction with 2 steps
1: Cl2 / Irradiation
View Scheme
Multi-step reaction with 2 steps
1: (bromination)
2: aq. ethanol
View Scheme
Multi-step reaction with 2 steps
1: SO2Cl2 / Heating
2: ethanol / Heating
View Scheme
Multi-step reaction with 2 steps
1: NBS
View Scheme
sodium cyanide
773837-37-9

sodium cyanide

3-fluorobenzyl methanesulfonate
1000370-26-2

3-fluorobenzyl methanesulfonate

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 0.5h;
Methyl formate
107-31-3

Methyl formate

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

2-(3-fluorophenyl)-3-hydroxyacrylonitrile
154858-22-7

2-(3-fluorophenyl)-3-hydroxyacrylonitrile

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 0 - 20℃; Inert atmosphere;100%
With sodium hydride In tetrahydrofuran at 0 - 20℃; Inert atmosphere;
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

5-[(3-fluorophenyl)methyl]-1H-1,2,3,4-tetrazole

5-[(3-fluorophenyl)methyl]-1H-1,2,3,4-tetrazole

Conditions
ConditionsYield
With sodium azide; triethylamine hydrochloride In toluene at 110℃; for 16h; Inert atmosphere;99%
2-Aminonicotinaldehyde
7521-41-7

2-Aminonicotinaldehyde

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

2-amino-3-(3-fluorophenyl)-1,8-naphthyridine
1082419-13-3

2-amino-3-(3-fluorophenyl)-1,8-naphthyridine

Conditions
ConditionsYield
With potassium hydroxide In water for 0.0416667h; Microwave irradiation;98%
ethanol
64-17-5

ethanol

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

ethyl 2-(3-fluorophenyl)acetimidate hydrochloride

ethyl 2-(3-fluorophenyl)acetimidate hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 0℃; for 48h;94%
With acetyl chloride at 0℃; Inert atmosphere;87%
With hydrogenchloride at 0 - 5℃;
With hydrogenchloride In toluene at 0 - 20℃; for 1h;6.12 g
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

methyl iodide
74-88-4

methyl iodide

2-(3-fluoro-phenyl)-2-methyl-propionitrile
93748-10-8

2-(3-fluoro-phenyl)-2-methyl-propionitrile

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile With lithium hexamethyldisilazane In tetrahydrofuran at -70 - -50℃; for 1h; Inert atmosphere;
Stage #2: methyl iodide In tetrahydrofuran at -50 - 20℃;
93%
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 17.5h;
With sodium hexamethyldisilazane In tetrahydrofuran at 0℃; for 0.75h;
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

diisopropyl-carbodiimide
693-13-0

diisopropyl-carbodiimide

C15H20FN3

C15H20FN3

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at 60℃; under 760.051 Torr; for 6h; Inert atmosphere; Sealed tube;92%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

3,3,3-trifluoro-2-phenylpropene
384-64-5

3,3,3-trifluoro-2-phenylpropene

C26H18F5N

C26H18F5N

Conditions
ConditionsYield
With lithium tert-butoxide In dimethyl sulfoxide at 80℃; for 12h; Inert atmosphere;92%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

methyl chloroformate
79-22-1

methyl chloroformate

methyl 2-cyano-2-(3-fluorophenyl)acetate

methyl 2-cyano-2-(3-fluorophenyl)acetate

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile With n-butyllithium; diisopropylamine In tetrahydrofuran; hexane at 20℃; for 0.166667h;
Stage #2: methyl chloroformate In tetrahydrofuran; hexane at -78℃; for 4.5h;
91%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

Phenyl azide
622-37-7

Phenyl azide

C14H11FN4

C14H11FN4

Conditions
ConditionsYield
With caesium carbonate In water; dimethyl sulfoxide at 25℃; regioselective reaction;90%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

benzyl alcohol
100-51-6

benzyl alcohol

2-(3-fluorophenyl)-3-phenylpropanamide

2-(3-fluorophenyl)-3-phenylpropanamide

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; triphenylphosphine; potassium hydroxide In tert-Amyl alcohol at 130℃; for 2h; Microwave irradiation;89%
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; triphenylphosphine; potassium hydroxide at 130℃; for 2h; Microwave irradiation; Green chemistry;89%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

N-hydroxybenzenecarboximidamide
613-92-3

N-hydroxybenzenecarboximidamide

5-(3-fluorobenzyl)-3-phenyl-1,2,4-oxadiazole
1165931-58-7

5-(3-fluorobenzyl)-3-phenyl-1,2,4-oxadiazole

Conditions
ConditionsYield
With toluene-4-sulfonic acid; zinc(II) chloride In N,N-dimethyl-formamide at 80℃; Inert atmosphere;88%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

benzoic acid tert-butyl ester
774-65-2

benzoic acid tert-butyl ester

N-(tert-butyl)-2-(3-fluorophenyl)acetamide
1091953-80-8

N-(tert-butyl)-2-(3-fluorophenyl)acetamide

Conditions
ConditionsYield
With zinc perchlorate In neat (no solvent) at 50℃; for 5h; Ritter Amidation;87%
acetic acid tert-butyl ester
540-88-5

acetic acid tert-butyl ester

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

N-(tert-butyl)-2-(3-fluorophenyl)acetamide
1091953-80-8

N-(tert-butyl)-2-(3-fluorophenyl)acetamide

Conditions
ConditionsYield
With water; iodine In toluene at 110℃; for 6h; Ritter reaction;86%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

2-amino-4-(N,N-dimethylamino)benzaldehyde
56669-96-6

2-amino-4-(N,N-dimethylamino)benzaldehyde

3-(3-fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

3-(3-fluorophenyl)-N7,N7-dimethylquinoline-2,7-diamine

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile With potassium tert-butylate In N,N-dimethyl-formamide at 0℃; for 0.25h;
Stage #2: 2-amino-4-(N,N-dimethylamino)benzaldehyde In N,N-dimethyl-formamide at 0 - 90℃;
84%
Stage #1: 3-fluorophenylacetonitrile With potassium tert-butylate In N,N-dimethyl-formamide at 0 - 20℃; for 0.25h;
Stage #2: 2-amino-4-(N,N-dimethylamino)benzaldehyde In N,N-dimethyl-formamide at 0 - 90℃;
methanol
67-56-1

methanol

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

2-(3-fluorophenyl)propanenitrile

2-(3-fluorophenyl)propanenitrile

Conditions
ConditionsYield
With cobalt(II) tetrafluoroborate hexahydrate; tris(2-diphenylphosphinoethyl)phosphine; potassium carbonate at 100℃; for 24h; Autoclave; Glovebox; Inert atmosphere;84%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

thiosemicarbazide
79-19-6

thiosemicarbazide

5-[(3-fluorophenyl)methyl]-1,3,4-thiadiazol-2-heptane
39181-54-9

5-[(3-fluorophenyl)methyl]-1,3,4-thiadiazol-2-heptane

Conditions
ConditionsYield
In trifluoroacetic acid at 60℃; for 3h;82%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

1-naphthyl tosylate
68211-49-4

1-naphthyl tosylate

2-(3-fluorophenyl)-2-(naphthalen-1-yl)acetonitrile

2-(3-fluorophenyl)-2-(naphthalen-1-yl)acetonitrile

Conditions
ConditionsYield
With potassium phosphate; palladium diacetate; XPhos In dichloromethane; tert-butyl alcohol at 110℃; for 4h; Inert atmosphere; Schlenk technique; Sealed tube;82%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

4-tert-butylphenyl mesylate
59970-38-6

4-tert-butylphenyl mesylate

2-(4-(tert-butyl)phenyl)-2-(3-fluorophenyl)acetonitrile

2-(4-(tert-butyl)phenyl)-2-(3-fluorophenyl)acetonitrile

Conditions
ConditionsYield
With potassium phosphate; palladium diacetate; XPhos In dichloromethane; tert-butyl alcohol at 110℃; for 4h; Inert atmosphere; Schlenk technique; Sealed tube;82%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

N,N-bis(2-chloro-ethyl)-benzenemethanamine
55-51-6

N,N-bis(2-chloro-ethyl)-benzenemethanamine

1-benzyl-4-(3-fluorophenyl)piperidine-4-carbonitrile
1158750-54-9

1-benzyl-4-(3-fluorophenyl)piperidine-4-carbonitrile

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile With 18-crown-6 ether; sodium hydride In tetrahydrofuran; N,N-dimethyl-formamide at 0℃; for 0.25h;
Stage #2: N,N-bis(2-chloro-ethyl)-benzenemethanamine In tetrahydrofuran; N,N-dimethyl-formamide at 0 - 20℃;
80%
Stage #1: 3-fluorophenylacetonitrile With sodium hydride In tetrahydrofuran at 20℃; for 2h;
Stage #2: N,N-bis(2-chloro-ethyl)-benzenemethanamine In tetrahydrofuran at 80℃; for 3h;
77%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

2-(3-fluorophenyl)ethan-1-amine hydrochloride

2-(3-fluorophenyl)ethan-1-amine hydrochloride

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile With borane-ammonia complex; C17H16BrMnN2O3S In hexane at 60℃; for 6h;
Stage #2: With hydrogenchloride In diethyl ether; water
80%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

C15H14NO3F

C15H14NO3F

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 25℃; for 0.25h;79%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

methyl 5-cyano-5-(3-fluorophenyl)-2-oxocyclohexanecarboxylate

methyl 5-cyano-5-(3-fluorophenyl)-2-oxocyclohexanecarboxylate

Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at 0 - 27℃; for 1h;78.8%
3,4-dimethylbenzaldehyde
5973-71-7

3,4-dimethylbenzaldehyde

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

(2E)-3-(3,4-dimethylphenyl)-2-(3-fluorophenyl)acrylonitrile
1379649-42-9

(2E)-3-(3,4-dimethylphenyl)-2-(3-fluorophenyl)acrylonitrile

Conditions
ConditionsYield
With sodium methylate In ethanol at 20℃; for 2h;78%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

N-(4-formylphenyl)carbazole
110677-45-7

N-(4-formylphenyl)carbazole

(Z)-3-(-4-(9H-carbazol-9-yl)phenyl)-2-(3-fluorophenyl)acrylonitrile

(Z)-3-(-4-(9H-carbazol-9-yl)phenyl)-2-(3-fluorophenyl)acrylonitrile

Conditions
ConditionsYield
With sodium methylate In methanol at 60℃; for 3h;78%
2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

2-[Cyano-(3-fluoro-phenyl)-methyl]-benzonitrile
127667-15-6

2-[Cyano-(3-fluoro-phenyl)-methyl]-benzonitrile

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 20℃; for 3h;77%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

formic acid ethyl ester
109-94-4

formic acid ethyl ester

2-(3'-Fluorophenyl)-3-oxopropanenitrile
75175-23-4

2-(3'-Fluorophenyl)-3-oxopropanenitrile

Conditions
ConditionsYield
With sodium hydride In various solvent(s) at 70 - 80℃; for 6h; Carbonylation;77%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

benzenecarbothioamide
2227-79-4

benzenecarbothioamide

3-(3-fluorobenzyl)-5-phenyl-1,2,4-thiadiazole

3-(3-fluorobenzyl)-5-phenyl-1,2,4-thiadiazole

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile; benzenecarbothioamide With aluminum (III) chloride In acetic acid butyl ester at 70℃; for 5h; Sealed tube;
Stage #2: With water; iodine In acetic acid butyl ester at 20℃; for 24h; Sealed tube; chemoselective reaction;
77%
1,1-Diphenylmethanol
91-01-0

1,1-Diphenylmethanol

3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

N-benzhydryl-2-(3-fluorophenyl)acetamide
791126-32-4

N-benzhydryl-2-(3-fluorophenyl)acetamide

Conditions
ConditionsYield
With water; iodine In toluene at 110℃; for 7h; Ritter reaction;76%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

1-naphthyl mesylate
38262-42-9

1-naphthyl mesylate

2-(3-fluorophenyl)-2-(naphthalen-1-yl)acetonitrile

2-(3-fluorophenyl)-2-(naphthalen-1-yl)acetonitrile

Conditions
ConditionsYield
With potassium phosphate; palladium diacetate; XPhos In dichloromethane; tert-butyl alcohol at 110℃; for 4h; Inert atmosphere; Schlenk technique; Sealed tube;76%
3-fluorophenylacetonitrile
501-00-8

3-fluorophenylacetonitrile

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N-(tert-butyl)-2-(3-fluorophenyl)acetamide
1091953-80-8

N-(tert-butyl)-2-(3-fluorophenyl)acetamide

Conditions
ConditionsYield
Stage #1: 3-fluorophenylacetonitrile; di-tert-butyl dicarbonate With copper(II) bis(trifluoromethanesulfonate) In neat (no solvent) at 20℃; for 5h; Ritter Amidation;
Stage #2: With water Ritter Amidation;
76%

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