Product Name

  • Name

    FUMAGILLIN

  • EINECS 245-433-8
  • CAS No. 23110-15-8
  • Article Data2
  • CAS DataBase
  • Density 1.199 g/cm3
  • Solubility ethanol: 1 mg/mL
  • Melting Point >190oC-192oC
  • Formula C26H34O7
  • Boiling Point 608.772 °C at 760 mmHg
  • Molecular Weight 458.552
  • Flash Point 198.793 °C
  • Transport Information
  • Appearance white powder
  • Safety 36
  • Risk Codes 22
  • Molecular Structure Molecular Structure of 23110-15-8 (FUMAGILLIN)
  • Hazard Symbols HarmfulXn
  • Synonyms 2,4,6,8-Decatetraenedioicacid 4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-1-oxaspiro[2.5]oct-6-ylester (6CI);2,4,6,8-Decatetraenedioic acid,mono[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl]ester, (2E,4E,6E,8E)- (9CI);2,4,6,8-Decatetraenedioic acid,mono[4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-1-oxaspiro[2.5]oct-6-yl]ester (8CI);2,4,6,8-Decatetraenedioic acid,mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl]ester, [3R-[3a,4a(2R*,3R*),5b,6b(2E,4E,6E,8E)]]-;Amebacilin;Fugillin;Fumadil B;Fumagillin;Fumagillin DCH;Fumidil;NSC 9168;297-95-0;
  • PSA 97.89000
  • LogP 3.91540

Fumagillin Chemical Properties

Molecular Structure of FUMIDIL(23110-15-8):

IUPAC Name:(2E,4E,6E,8E)-10-[[(3S,4R,5R,6S)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid
Molecular Formula:C26H34O7
Molecular Weight:458.543960 g/mol
Appearance:white powder
Density:1.19 g/cm3
Flash Point:198.8 °C
Enthalpy of Vaporization:103.73 kJ/mol
Boiling Point:608.8 °C at 760 mmHg
Vapour Pressure:2.31E-17 mmHg at 25 °C
Ethanol Solubility:1 mg/mL
Water Solubility:11.93 mg/L at 25 °C
EINECS:245-433-8
Synonyms of FUMIDIL(23110-15-8):
1-oxaspiro(2,5)oct-6-ylester;2,4,6,8-decatetraenedioicacid,mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-buteny;5beta,6beta(all-e)]]-theta;6,8-decatetraenedioicacid,4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-4;amebacillin;fugilin;fumidil;h-3
Categories of FUMIDIL(23110-15-8):
Peptide Synthesis/Antibiotics

Fumagillin Toxicity Data With Reference

1.    

orl-mus LD50:2000 mg/kg

    85ERAY    Antibiotics: Origin, Nature, and Properties. 3 (1978),1834.
2.    

scu-mus LD50:800 mg/kg

    ANTCAO    Antibiotics and Chemotherapy. 1 (1951),54.

Fumagillin Safety Profile

The safety information of FUMIDIL(23110-15-8) is as follows:
Hazard Codes:Xn
Risk Statements:22
22:Harmful if swallowed
Safety Statements:36
36:Wear suitable protective clothing
WGK Germany:3
RTECS:HE1750000
Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes.

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