Product Name

  • Name

    1H-1,2,4-Triazole-3,5-diamine

  • EINECS 215-937-2
  • CAS No. 1455-77-2
  • Article Data24
  • CAS DataBase
  • Density 1.686 g/cm3
  • Solubility Soluble in water.
  • Melting Point 202-205 °C(lit.)
  • Formula C2H5N5
  • Boiling Point 473.7 °C at 760 mmHg
  • Molecular Weight 99.0952
  • Flash Point 271.6 °C
  • Transport Information
  • Appearance colourless crystals or faintly yellow powder
  • Safety 36/37-45-36/37/39-27-26
  • Risk Codes 22-34
  • Molecular Structure Molecular Structure of 1455-77-2 (1H-1,2,4-Triazole-3,5-diamine)
  • Hazard Symbols HarmfulXn, IrritantXi, CorrosiveC
  • Synonyms Guanazole(6CI,7CI,8CI);3,5-Diamino-1,2,4-triazole;3,5-Diamino-1H-1,2,4-triazole;3,5-Diamino-s-triazole;NSC 166592;NSC 167391;NSC 167392;NSC 1895;
  • PSA 93.61000
  • LogP 0.13150

Guanazole Chemical Properties

The Molecular formula of 3,5-DIAMINO-s-TRIAZOLE(1455-77-2): C2H5N5
The Molecular Weight of 3,5-DIAMINO-s-TRIAZOLE(1455-77-2): 99.09
Molecular Structure : 
EINECS: 215-937-2
Index of Refraction: 1.809 
Molar Refractivity: 25.34 cm
Molar Volume: 58.7 cm
Polarizability: 10.04 10-24 cm3 
Surface Tension: 153.5 dyne/cm 
Density: 1.686 g/cm
Boiling Point: 473.7 °C at 760 mmHg 
Flash Point: 271.6 °C 
Enthalpy of Vaporization: 73.69 kJ/mol 
Vapour Pressure: 3.85E-09 mmHg at 25°C
Appearance: colourless crystals or faintly yellow powder
Stability: Stability Air sensitive. Reacts with acids and oxidizing agents.
IUPAC Name: 1H-1,2,4-triazole-3,5-diamine
Synonyms: 4H-1,2,4-TRIAZOLE-3,5-DIAMINE;3,5-DIAMINO-1H-1,2,4-TRIAZOLE;1H-1,2,4-TRIAZOLE-3,5-DIAMINE;GUANAZOLE;TIMTEC-BB SBB004371;1,2,4-Triazolidine, 3,5-diimino-;3-AMINO-1H-1,2,4-TRIAZOL-5-YLAMINE;3,5-DIAMINO-1,2,4-TRIAZOLE;

Guanazole Toxicity Data With Reference

1.human TDLo intravenous 8620mg/kg/5D (8620mg/kg)
  Effect: BLOOD: LEUKOPENIA ;   BLOOD: THROMBOCYTOPENIA
  Source: Cancer Chemotherapy Reports, Part 1. Vol. 59, Pg. 1117, 1975.
2.quail LD50 oral > 316mg/kg (316mg/kg)   Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982.

Guanazole Consensus Reports

NCI Carcinogenesis Studies (ipr); Equivocal Evidence: rat CANCAR    Cancer. 40 (1977),1935. ; No Evidence: mouse CANCAR    Cancer. 40 (1977),1935. . Reported in EPA TSCA Inventory.

Guanazole Safety Profile

Human systemic effects by intravenous route: leukopenia (reduced white blood cell count) and thrombocytopenia (reduced blood platelet count). Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
The Hazard Codes of 3,5-DIAMINO-s-TRIAZOLE(1455-77-2):   Xn,Xi,   C
HS Code: 29339990
The Risk Statements information of 3,5-DIAMINO-s-TRIAZOLE(1455-77-2):
22:  Harmful if swallowed 
34:  Causes burns 
The Safety Statements information of 3,5-DIAMINO-s-TRIAZOLE(1455-77-2):
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
27:  Take off immediately all contaminated clothing 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
36/37:  Wear suitable protective clothing and gloves 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 
WGK Germany: 3
RTECS: XZ4535000
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