L(+)-Arginine supplier | CasNO.74-79-3

Name
L(+)-Arginine
EINECS 200-811-1
CAS No. 74-79-3
Article Data212
CAS DataBase
Density 1.467 g/cm³
Solubility 148.7 g/L (20 °C) in water
Melting Point 222 °C (dec.)(lit.)
Formula C₆H₁₄N₄O₂
Boiling Point 409.14 °C at 760 mmHg
Molecular Weight 174.203
Flash Point 201.241 °C
Transport Information
Appearance white crystalline powder
Safety 24/25-36-26
Risk Codes 36-36/37/38-20/21/22
Molecular Structure
Hazard Symbols Xn
Synonyms Arginine,L- (8CI);(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid;Arginine;L-Arg;L-Norvaline,5-[(aminoiminomethyl)amino]-;L-Ornithine, N5-(aminoiminomethyl)-;L-a-Amino-d-guanidinovalericacid;NSC 206269;Pentanoic acid, 2-amino-5-[(aminoiminomethyl)amino]-, (S)-;H-Arg-OH;L-Arginine (Base);L-Arginine Base;
PSA 125.22000
LogP 0.55280

Synthetic route

: 13836-37-8
Boc-Arg(Tos)-OH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With phenylthiotrimethylsilane; pertrimethylsilylated Nafion; 3-methyl-phenol; trifluoroacetic acid for 3h;	100%

: 68262-73-7
Z(OMe)-Arg(Mts)-OH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; diphenyl sulfide In trifluoroacetic acid at 0℃; for 30h;	100%
With trimethylsilyl trifluoromethanesulfonate; diphenyl sulfide In trifluoroacetic acid at 0℃; for 0.5h; Product distribution; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed; effect of var. hard bases; var. reaction cond.;	100%

: 2149-70-4
Nω-nitro-L-arginine

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With phenylthiotrimethylsilane; pertrimethylsilylated Nafion; 3-methyl-phenol; trifluoroacetic acid for 3h;	100%

: 78221-85-9
cyclohexylammonium salt of Nα-benzyloxycarbonyl-NG-p-toluenesolfonyl-L-arginine

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; methoxybenzene In trifluoroacetic acid at 0℃; for 1h; Product distribution; various time, various temperature;	100%

: 91000-69-0
Fmoc-L-Arg-OH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With sodium azide In N,N-dimethyl-formamide at 50℃; for 3h;	95%

: 75806-97-2
NG-Mds-Arg

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With methyl-phenyl-thioether; trifluoroacetic acid at 50℃; for 4h; Product distribution; deprotection of several NG-protected arginine derivatives;	94.4%

: 67320-28-9
Z(OMe)-Arg(MBS)-OH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether In trifluoroacetic acid at 0℃; for 0.5h;	93.5%
With trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether In trifluoroacetic acid at 0℃; for 0.5h; Product distribution; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed.;	93.5%

: 13650-38-9
Nα-Benzyloxycarbonyl-Nω-tosyl-L-arginin

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether In trifluoroacetic acid at 0℃; for 1h; Product distribution; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed.;	86%
With trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether In trifluoroacetic acid at 0℃; for 0.5h;	62.1%

: 5-[amino(iminomethyl)]amino-2-[(E,Z)-4,4,4-trichloro-3-oxo-1-butenylamino]pentanoic acid

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 70℃; for 20h;	83%

: 5-[amino(iminomethyl)]amino-2-[(E,Z)-4,4,4-trifluoro-3-oxo-1-butenylamino]pentanoic acid

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 70℃; for 20h;	82%

: (S)-4-(3-guanidinopropyl)-2,2-borabyciclo[3.3.1]nonane-1,3,2-oxazaborolidin-5-one

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With hydrogenchloride In methanol; water at 20℃; for 0.5h; Inert atmosphere;	74%

: C6H14N4O2*H3N*ClH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane	68%

: 2304-98-5
N5-[imino(nitroamino)methyl]-N2-[(phenylmethoxy)carbonyl]-L-ornithine

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether In trifluoroacetic acid at 0℃; for 0.5h;	11%

: Z-Arg(NO2)-OH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With trimethylsilyl trifluoromethanesulfonate; methyl-phenyl-thioether In trifluoroacetic acid at 0℃; for 0.5h; Product distribution; New peptide deprotection procedure: hard-soft acid-base concept; the role of soft bases (thioanisole, dimethylsulfide, diphenylsulfide) employed.;	11%

: 70-26-8, 348-66-3, 616-07-9, 7006-33-9
D-ornithine

: 420-04-2
CYANAMID

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With barium dihydroxide; water

: 7200-25-1
Arg

A: 70-26-8, 348-66-3, 616-07-9, 7006-33-9
D-ornithine

B: 74-79-3
L-arginine

C: 57-13-6
urea

Conditions

Conditions	Yield
Reaktion des Carbonats bei der Einw. von Leberpresssaft (Arginase);

...Expand

: 372-75-8
Citrulline

: 74-79-3
L-arginine

Conditions

Conditions	Yield
Ueber die enzymatische Bildung;

: 1159-15-5
Nα-p-tosyl-L-arginine

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid; phenol

: 70-26-8
L-ornithine

: 2986-19-8
carbamimidothioic acid methyl ester

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With barium dihydroxide

: 506-68-3
bromocyane

: 70-26-8
L-ornithine

: 74-79-3
L-arginine

Conditions

Conditions	Yield
Yield given. Multistep reaction;

: 7200-25-1
Arg

A: 157-06-2
D-arginine

B: 74-79-3
L-arginine

: 1234-35-1
Z-Arg-OH

A: 74-79-3
L-arginine

B: 100-51-6
benzyl alcohol

Conditions

Conditions	Yield
With cobalt(II); urethane hydrolase II at 33℃; for 2h; Product distribution; Kinetics; phosphate buffer pH 6.5;

: 7182-70-9, 13345-48-7
L-arginine β-naphthylamide

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With phosphate buffer; bovine leukocyte aminopeptidase (BL-APase) at 37℃; pH=7.0;

: 58810-06-3
H-Arg(Mts)-OH

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With methyl-phenyl-thioether; trifluoroacetic acid at 28℃; for 24h; Product distribution; var. reag.: dimethylsulfide, ethanedithiol, 2-mercaptoethanol; var. time;

: 58-82-2
bradykinin

A: 74-79-3
L-arginine

B: 15958-92-6
des-Arg(9)-BK

Conditions

Conditions	Yield
With wheat carboxypeptidase from wheat bran at 30℃; Rate constant; pH 4.0; structure-reactivity relationship;

: 58-82-2
bradykinin

A: 56-45-1
L-serin

B: 74-79-3
L-arginine

C: 63-91-2
L-phenylalanine

D: 56-40-6
glycine

E: 147-85-3
L-proline

Conditions

Conditions	Yield
With 155K Aspergillus oryzae ACID CPASE O at 30℃; for 1h; pH 3.7, release of C-terminal amino acid residues at longer incubation times;

...Expand

: Pyoverdine Pa

: 74-79-3
L-arginine

Conditions

Conditions	Yield
hydrolysis;

: 126399-19-7
L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycyl-L-arginine

A: 74-79-3
L-arginine

B: L-Tyrosyl-D-alanyl-glycyl-L-phenylalanyl-L-neopentylglycine

Conditions

Conditions	Yield
With TES buffer; carboxypeptidase B at 37℃; Product distribution; Determination of the rate of enzymatic degradation;

: 112160-37-9
NG-2,2,5,7,8-pentamethylchroman-6-sulfonyl-L-arginine

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With hydrogen bromide In acetic acid for 0.0833333h; Ambient temperature;
With TFA - thioanisole; hydrogen bromide; acetic acid; trifluoroacetic acid for 2h; Product distribution; Ambient temperature;

: 105330-48-1
3-(N-suberoylargininyl)hellebrigenin

: 74-79-3
L-arginine

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 10h;

: 2-ethoxy-3-[4-{3-(4-methanesulfonyloxyphenyl)propylamino}phenyl]propionic acid

: 74-79-3
L-arginine

: 2-ethoxy-3-[4-{3-(4-methanesulfonyloxyphenyl) propylamino}phenyl]propionic acid arginine salt

Conditions

Conditions	Yield
In methanol at 20℃; for 2 - 3h;	100%

: (S)-2-methoxy-3-[4-{6-methanesulfonyloxynaphth-2-ylmethylamino}phenyl]propanoic acid

: 74-79-3
L-arginine

: (S)-2-methoxy-3-[4-{6-methanesulfonyloxynaphth-2-ylmethylamino}phenyl]propanoic acid arginine salt

Conditions

Conditions	Yield
In methanol at 20℃; for 2 - 3h;	100%

: 74-79-3
L-arginine

: 119141-88-7
esomeprazole

: 942472-45-9
esomeprazole L-arginine salt

Conditions

Conditions	Yield
In methanol; water	100%

: 74-79-3
L-arginine

: 41639-83-2
latanoprost acid

: 1224443-39-3
latanoprost L-arginine salt

Conditions

Conditions	Yield
In methanol; water for 0.5h; Product distribution / selectivity;	100%
In methanol; water for 0.5h; Product distribution / selectivity;

: 74-79-3
L-arginine

: 54276-17-4
(+)-fluprostenol

: 1224443-24-6
arginyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-enyl)cyclopentyl)hept-5-enoate

Conditions

Conditions	Yield
In methanol; water for 0.5h;	100%
In methanol; water for 0.5h;

: 74-79-3
L-arginine

: (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo [1,5-a]pyrazine-1-carboxylic acid

: (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxylic acid (2S)-2-amino-5-guanidino-pentanoic acid

Conditions

Conditions	Yield
In methanol; water for 4h;	100%

: 74-79-3
L-arginine

: 1174122-63-4
(R)-7-[3-amino-4-(2,4,5-trifluorophenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo [1,5-a]pyrazine-1-carboxylic acid

: 1242332-84-8
(R)-7-[3-amino-4-(2,4,5-trifluorophenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo [1,5-a]pyrazine-1-carboxylic acid-(2S)-2-amino-5-carbamimidamidopentanoic acid

Conditions

Conditions	Yield
In methanol; water for 4h;	100%
In methanol; water for 4h;	100%

: 74-79-3
L-arginine

: (S)-2-((5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenamido)-4-methylpentanoic acid

: C6H14N4O2*C26H41NO3

Conditions

Conditions	Yield
In methanol at 20℃; for 2h;	100%

: 74-79-3
L-arginine

: 4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acid

: 4-{[(6-bromo-3-methyl-2-phenylquinolin-4-yl)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acid L-arginine salt

Conditions

Conditions	Yield
In ethanol; water Heating;	100%

: 74-79-3
L-arginine

: 17720-18-2
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate (S)-2-ammonio-5-guanidinopentanoate

Conditions

Conditions	Yield
In water Cooling with ice;	100%

: 74-79-3
L-arginine

: nicotinic acid riboside 5'-monophosphate

: (S)-1-carboxy-4-guanidinobutan-1-aminium 1-((2R,3R,4S,5R)-5-(((hydrogenphosphonato)oxy)methyl)-3,4-dihydroxyterahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

Conditions

Conditions	Yield
In water at 10℃; pH=Ca. 4.6 - 4.9;	100%

: 74-79-3
L-arginine

: nicotinic acid riboside 5'-monophosphate

: bis((S)-1-carboxy-4-guanidinobutan-1-aminium)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonatooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

Conditions

Conditions	Yield
In water at 10℃; pH=Ca. 7 - 7.2;	100%

: 59-67-6
nicotinic acid

: 74-79-3
L-arginine

: L-arginine nicotinate

Conditions

Conditions	Yield
In water for 0.166667h; pH=Ca. 6 - 6.2; Cooling with ice;	100%

: 223607-27-0
(-)-3-[4-[2-(2,3-dihydro-1,4-benzothiazin-4-yl)ethoxy]phenyl]-2-ethoxypropanoic acid

: 74-79-3
L-arginine

: 305827-56-9
(-)-3-[4-[2-(2,3-dihydro-1,4-benzothiazin-4-yl)ethoxy]phenyl]-2-ethoxypropanoic acid, arginine salt

Conditions

Conditions	Yield
In ethanol; water at 20 - 50℃; for 10h;	99.5%

: 74-79-3
L-arginine

: C43H51N7O9S2

: (x)C6H14N4O2*C43H51N7O9S2

Conditions

Conditions	Yield
In methanol at 20℃;	99.31%

: 74-79-3
L-arginine

: nicotinic acid riboside 5'-monophosphate

: (S)-1-carboxy-4-guanidinobutan-1-aminium ((2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate

Conditions

Conditions	Yield
In water at 10℃; pH=Ca. 6.8 - 7;	99%

: 74-79-3
L-arginine

: 125111-32-2
1H,2H,2H-perfluoro-1-octyl succinic acid monoester

: C12H9F13O4*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 1H,1H,2H,2H-perfluoro-1-decyl succinic acid monoester

: C14H9F17O4*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 1H,1H,2H,2H-perfluoro-1-octyl glutaric acid monoester

: C13H11F13O4*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 1H,1H,2H,2H-perfluoro-1-decyl glutaric acid monoester

: C15H11F17O4*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 1H,1H,2H,2H-perfluoro-1-octylphthalic acid monoester

: C16H9F13O4*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 1H,1H,2H,2H-perfluoro-1-decyl phthalic acid monoester

: C18H9F17O4*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 36390-05-3
2-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-malonic acid

: 2C6H14N4O2*C13H7F17O4

Conditions

Conditions	Yield
In methanol; water Heating;	99%

: 74-79-3
L-arginine

: 220072-62-8
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-1-octa-6-thiohexanoic acid

: C14H15F13O2S*C6H14N4O2

Conditions

Conditions	Yield
In methanol; water for 2h; Reflux;	99%

: 74-79-3
L-arginine

: 87333-19-5
Ramipril

: ramipril-(L)-arginine

Conditions

Conditions	Yield
In water; isopropyl alcohol at 20℃; for 0.5h;	98%
In butanone for 0.5h; Product distribution / selectivity; Heating / reflux;

: 74-79-3
L-arginine

: 90-02-8
salicylaldehyde

: L-salicylidenearginine

Conditions

Conditions	Yield
In ethanol for 12h; Reflux;	98%
In methanol for 24.5h; Reflux;

L(+)-Arginine Specification

L(+)-Arginine (CAS NO.74-79-3) is also named as (S)-2-Amino-5-((aminoiminomethyl)amino)pentanoic acid. It is white crystalline powder. In mammals, L(+)-Arginine is classified as a semiessential or conditionally essential amino acid, depending on the developmental stage and health status of the individual. This chemical belongs to the Product Categories which include pharmacetical;chiral;Arginine [Arg, R];Amino Acids;Amino Acids and Derivatives;for Resolution of Acids;Optical Resolution;alpha-Amino Acids;Biochemistry;Synthetic Organic Chemistry;L-Amino Acids;Amino Acids;Nitric Oxide.

Physical properties about L(+)-Arginine are: (1)ACD/LogP: -0.999; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -4.50; (4)ACD/LogD (pH 7.4): -4.49; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00 ; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 6; (10)#H bond donors: 7; (11)#Freely Rotating Bonds: 6; (12)Index of Refraction: 1.601; (13)Molar Refractivity: 40.696 cm³; (14)Molar Volume: 118.724 cm³; (15)Polarizability: 16.133 10-24cm³; (16)Surface Tension: 66.1480026245117 dyne/cm; (17)Density: 1.467 g/cm³; (18)Flash Point: 201.241 °C; (19)Enthalpy of Vaporization: 72.555 kJ/mol; (20)Boiling Point: 409.14 °C at 760 mmHg

Preparation of L(+)-Arginine: L(+)-Arginine (CAS NO.74-79-3) is synthesized from citrulline by the sequential action of the cytosolic enzymes argininosuccinate synthetase (ASS) and argininosuccinate lyase (ASL).

Uses of L(+)-Arginine: L(+)-Arginine plays an important role in cell division, the healing of wounds, removing ammonia from the body, immune function, and the release of hormones. It is also used as precursor for the synthesis of nitric oxide (NO). And it can reduces healing time of injuries (particularly bone), quickens repair time of damaged tissue and helps decrease blood pressure.

When you are using this chemical, please be cautious about it as the following:
1. Avoid contact with skin and eyes;
2. Wear suitable protective clothing;
3. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice;

You can still convert the following datas into molecular structure:
(1).Canonical SMILES: C(CC(C(=O)O)N)CN=C(N)N
(2).Isomeric SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N
(3).InChI: InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
(4).InChIKey: ODKSFYDXXFIFQN-BYPYZUCNSA-N

Product Name

L(+)-Arginine

Synthetic route

L(+)-Arginine Specification

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