Product Name: Linadryl hydrochloride
CAS Registry Number: 5928-69-8
IUPAC Name: 4-(2-benzhydryloxyethyl)morpholine hydrochloride
Molecular Weight: 333.85236 [g/mol]
Molecular Formula: C19H24ClNO2
H-Bond Donor: 1
H-Bond Acceptor: 3
Flash Point: 128.9 °C
Enthalpy of Vaporization: 65.38 kJ/mol
Boiling Point: 402.6 °C at 760 mmHg
Vapour Pressure: 1.08E-06 mmHg at 25°C
Following is the molecular structure of Linadryl hydrochloride (CAS NO.5928-69-8) is:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | 70mg/kg (70mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
guinea pig | LD50 | intraperitoneal | 160mg/kg (160mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 83, Pg. 120, 1945. | |
mouse | LD50 | intraperitoneal | 185mg/kg (185mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
mouse | LD50 | oral | 327mg/kg (327mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
mouse | LD50 | subcutaneous | 440mg/kg (440mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
rabbit | LD50 | intravenous | 21mg/kg (21mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
rat | LD50 | intraperitoneal | 185mg/kg (185mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 102, Pg. 250, 1951. | |
rat | LD50 | intravenous | 35mg/kg (35mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
rat | LD50 | oral | 916mg/kg (916mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 89, Pg. 227, 1947. |
Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl.
Linadryl hydrochloride , its cas register number is 5928-69-8. It also can be called A 446 ; A 446 hydrochloride ; Linadryl hydrochloride ; beta-Morpholinoethyl benzhydryl ether hydrochloride ; Morpholine, 4-(2-(diphenylmethoxy)ethyl)-, hydrochloride .
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