Mercurophylline supplier | CasNO.8012-34-8

Name
MERCUROPHYLLINE
EINECS
CAS No. 8012-34-8
Density
Solubility
Melting Point
Formula C₁₄H₂₄HgNO₅•C₇H₈N₄O₂•Na
Boiling Point 442.9°C at 760 mmHg
Molecular Weight 690.16
Flash Point 221.7°C
Transport Information
Appearance
Safety Poison by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by intravenous route: cardiac arrythmias. When heated to decomposition it emits toxic fumes of Hg. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms novurit;mercuzanthin;mercuzan;merthylline;mercupurin;mixturewiththeophylline;mercurin;novurite;
PSA 95.86000
LogP 1.82390

Mercurophylline Chemical Properties

IUPAC Name: Sodium; 1,3-dimethyl-7H-purine-2,6-dione; mercury(2+); 3-(2-methoxypropylcarbamoyl)-1,2,2-trimethylcyclopentane-1-carboxylate; hydroxide
Synonyms of Mercurophylline (CAS NO.8012-34-8): A mixture of sodium salt of 3-(3-(hydroxymercuri)-2-methoxypropyl)camphoramic acid (C₁₄H₂₄HgNNaO₅) and theophylline (C₇H₈N₄O₂) ; Mercupurin ; Mercurin ; Mercurofilina ; Mercurophyllinum ; Novurite ; Osmuryl ; Mercurate(1-), (3-(((3-carboxylato-2,2,3-trimethylcyclopentyl)carbonyl)amino)-2-methoxypropyl)hydroxy-, monosodium salt, mixt.with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione ; Sodium (3-(((3-carboxylato-2,2,3-trimethylcyclopentyl)carbonyl)amino)-2-methoxypropyl)hydroxymer curate(1-), mixt. with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
CAS NO: 8012-34-8
Molecular Formula: C₂₁H₃₂HgN₅NaO7
Molecular Weight : 690.0878
Molecular Structure:
H bond acceptors: 5
H bond donors: 2
Freely Rotating Bonds: 5
Polar Surface Area: 66.84 Å²
Flash Point: 221.7 °C
Enthalpy of Vaporization: 76.79 kJ/mol
Boiling Point: 442.9 °C at 760 mmHg
Vapour Pressure: 4.41E-09 mmHg at 25°C

Mercurophylline Uses

Mercurophylline (CAS NO.8012-34-8) is kidney / urinary system drug.

Mercurophylline Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	250mg/kg (250mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 149, 1950.
human	TDLo	intravenous	28mg/kg (28mg/kg)	CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)	JAMA, Journal of the American Medical Association. Vol. 117, Pg. 1806, 1941.
mouse	LD50	intravenous	1410mg/kg (1410mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 149, 1950.
mouse	LD50	subcutaneous	163mg(Hg)/kg (163mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 336, 1952.
rabbit	LDLo	intravenous	177mg/kg (177mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 149, 1950.
rat	LD50	intraperitoneal	121mg/kg (121mg/kg)		Therapie. Vol. 10, Pg. 936, 1955.

Mercurophylline Consensus Reports

Mercury and its compounds are on the Community Right-To-Know List.

Mercurophylline Safety Profile

Poison by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by intravenous route: cardiac arrythmias. When Mercurophylline (CAS NO.8012-34-8) is heated to decomposition, it emits toxic fumes of Hg. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC.

Mercurophylline Standards and Recommendations

OSHA PEL: CL 0.1 mg(Hg)/m³ (skin)
ACGIH TLV: TWA 0.1 mg(Hg)/m³ (skin); BEI: 35 µg/g creatinine total inorganic mercury in urine preshift; 15 µg/g creatinine total inorganic mercury in blood at end of shift at end of workweek.
DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans
NIOSH REL: (Mercury, Aryl and Inorganic) CL 0.1 mg/m³ (skin)

Product Name

MERCUROPHYLLINE