Mevinphos supplier | CasNO.7786-34-7

Name
MEVINPHOS
EINECS 232-095-1
Annex I Index No: 015-020-00-5
B
CAS No. 7786-34-7
Density 1.216g/cm³
Solubility

Stability

Stable. Combustible. Incompatible with strong oxidizing agents.

Toxicology

Very toxic, and may be fatal, in contact with the skin, if inhaled and if swallowed. Exposure cancause a wide range of s

Melting Point -56 C (quoted by chemical supplier, though other sources givevalues in the range +7 to +14C)
Formula C7H13 O6 P
Boiling Point 110 C
Molecular Weight 224.15
Flash Point 115.1°C
Transport Information
Appearance colourless liquid
Safety Poison by ingestion, inhalation, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: peripheral motor nerve recording changes. An insecticide. When heated to decomposition it emits toxic fumes of PO_x.
Analytical Methods:

For occupational chemical analysis use NIOSH: Mevinphos (Phosdrin) 2503.
Risk Codes R27/28; R50/53; R67; R65; R38; R11
Molecular Structure
Hazard Symbols Toxic by ingestion, inhalation, and skin absorption; use may be restricted; cholinesterase inhibitor. TLV: TWA 0.01 ppm; STEL 0.03 ppm.
Synonyms Crotonicacid, 3-hydroxy-, methyl ester, dimethyl phosphate (6CI,8CI);1-Methoxycarbonyl-1-propen-2-yl dimethyl phosphate;2-Carbomethoxy-1-methylvinyl dimethyl phosphate;2-Methoxycarbonyl-1-methylvinyl dimethyl phosphate; CMDP; Fosdrin; Gesfid;Meniphos; Mevinphos; NSC 46470; O,O-Dimethyl O-(1-carbomethoxy-1-propen-2-yl)phosphate; PD 5; PD 5 (pesticide); Phosdrin; Phosdrin W 10
PSA 91.87000
LogP 0.86910

Synthetic route

: 4755-81-1
methyl 2-chloroacetoacetate

: 121-45-9
phosphorous acid trimethyl ester

: 7786-34-7
phosdrin

Conditions

Conditions	Yield
Heating;

: 7786-34-7
phosdrin

: C20H12EuNO12

: C20H12EuNO12*C7H13O6P

Conditions

Conditions	Yield
In ethanol at 19.84℃; Temperature; Solvent;

: 7786-34-7
phosdrin

: C20H12EuNO12

: C20H12NO12Tb*C7H13O6P

Conditions

Conditions	Yield
In ethanol at 19.84℃; Temperature; Solvent;

Mevinphos Chemical Properties

The IUPAC name of Mevinphos (CAS NO.7786-34-7): Methyl (E)-3-dimethoxyphosphoryloxybut-2-enoate
Synonyms: Duraphos ; E-Mevinphos;e-mevinphos (trans) ; Mevindrin ; Mevinphos ; 3-Hydroxy-crotonic acid methyl ester dimethyl phosphate ; 2-Carbomethoxy-1-methylvinyldimethyl phosphate ; 2-Methoxycarbonyl-1-methylvinyl dimethyl phosphate
CAS: 7786-34-7
EINECS: 232-095-1
Molecular Formula: C₇H₁₃O₆P
Molecular Structure:

Formula Weight: 224.15 g/mol
Index of Refraction: 1.437
Density: 1.216 g/cm³
Flash Point: 115.1 °C
Boiling Point: 243.4 °C at 760 mmHg

Mevinphos Toxicity Data With Reference

The toxicity of Mevinphos (CAS NO.7786-34-7):

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD₅₀	oral	1400ug/kg (1.4mg/kg)		Journal de Toxicologie Clinique et Experimentale. Vol. 6(3), Pg. 175, 1986.
duck	LD₅₀	oral	4600ug/kg (4.6mg/kg)		Down to Earth. Vol. 35, Pg. 25, 1979.
duck	LD₅₀	skin	11mg/kg (11mg/kg)		Toxicology and Applied Pharmacology. Vol. 47, Pg. 451, 1979.
gerbil	LD₅₀	intraperitoneal	450ug/kg (0.45mg/kg)		Toxicology and Applied Pharmacology. Vol. 36, Pg. 195, 1976.
man	TDLo	oral	700ug/kg/28D- (0.7mg/kg)	PERIPHERAL NERVE AND SENSATION: RECORDING FROM PERIPHERAL MOTOR NERVE	Toxicology and Applied Pharmacology. Vol. 42, Pg. 351, 1977.
mouse	LD₅₀	intraperitoneal	2mg/kg (2mg/kg)		Canadian Journal of Biochemistry and Physiology. Vol. 39, Pg. 1790, 1961.
mouse	LD₅₀	intravenous	680ug/kg (0.68mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967.
mouse	LD₅₀	oral	4mg/kg (4mg/kg)	GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: TREMOR	AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 45, 1954.
mouse	LD₅₀	skin	12mg/kg (12mg/kg)		Journal of Toxicology and Environmental Health. Vol. 9, Pg. 491, 1982.
mouse	LD₅₀	subcutaneous	1180ug/kg (1.18mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 19, Pg. 612, 1967.
pigeon	LD₅₀	oral	4210ug/kg (4.21mg/kg)		ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
quail	LD₅₀	oral	23700ug/kg (23.7mg/kg)		ASTM Special Technical Publication. Vol. (680), Pg. 157, 1979.
rabbit	LD₅₀	skin	4700ug/kg (4.7mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 353, 1973.
rat	LC₅₀	inhalation	14ppm/1H (14ppm)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 45, 1954.
rat	LD₅₀	intraperitoneal	800ug/kg (0.8mg/kg)		Advances in Pest Control Research. Vol. 4, Pg. 117, 1961.
rat	LD₅₀	oral	3mg/kg (3mg/kg)		Down to Earth. Vol. 35, Pg. 25, 1979.
rat	LD₅₀	skin	4200ug/kg (4.2mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT	Toxicology and Applied Pharmacology. Vol. 2, Pg. 88, 1960.
rat	LD₅₀	subcutaneous	940ug/kg (0.94mg/kg)		Folia Medica Vol. 24(4), Pg. 23, 1982.

Mevinphos Consensus Reports

EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.

Mevinphos Safety Profile

The Hazard Codes of Mevinphos (CAS NO.7786-34-7): Very T+ Dangerous N Harmful XnF
Risk Statements:R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R67:Vapours may cause drowsiness and dizziness. R65:Harmful: may cause lung damage if swallowed. R38:Irritating to skin. R11:Highly flammable.
Safety Statements:S23:Do not breathe vapour. S28:After contact with skin, wash immediately with plenty of soap-suds. S36/37:Wear suitable protective clothing and gloves. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S60:This material and its container must be disposed of as hazardous waste. S61:Avoid release to the environment. Refer to special instructions / safety data sheets. S62:If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label.
Poison by ingestion, inhalation, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: peripheral motor nerve recording changes. An insecticide. When heated to decomposition it emits toxic fumes of PO_x.