Product Name

  • Name

    MEFEXAMIDE HYDROCHLORIDE

  • EINECS
  • CAS No. 1227-61-8
  • Density 1.0586 (rough estimate)
  • Solubility
  • Melting Point
  • Formula C15H24 N2 O3
  • Boiling Point 460.4°C at 760 mmHg
  • Molecular Weight 280.367
  • Flash Point 232.2°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1227-61-8 (MEFEXAMIDE HYDROCHLORIDE)
  • Hazard Symbols T+
  • Synonyms Acetamide,N-[2-(diethylamino)ethyl]-2-(p-methoxyphenoxy)- (7CI,8CI); ANP 297; Mefexadyne;Mefexamide; Mephexamide; Mexephenamide;N-[2-(Diethylamino)ethyl]-2-(p-methoxyphenoxy)acetamide; NP 297; Timodyne
  • PSA 50.80000
  • LogP 2.72490

N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide Chemical Properties

IUPAC Name: N-(2-Diethylaminoethyl)-2-(4-methoxyphenoxy)acetamide
Synonyms of N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide (CAS NO.1227-61-8): 2-(p-Methoxyphenoxy)-N-(2-(diethylamino)ethyl)acetamide ; Acetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)- ; Mefaxadyne ; Mefexamidum ; Mexephenamide ; Timodyne ; Acetamide, N-(2-(diethylamino)ethyl)-2-(p-methoxyphenoxy)-
InChI: InChI=1/C15H24N2O3/c1-4-17(5-2)11-10-16-15(18)12-20-14-8-6-13(19-3)7-9-14/h6-9H,4-5,10-12H2,1-3H3,(H,16,18)
InChIKey: HUNIPYLVUPMFCZ-UHFFFAOYAJ
Std. InChI: InChI=1S/C15H24N2O3/c1-4-17(5-2)11-10-16-15(18)12-20-14-8-6-13(19-3)7-9-14/h6-9H,4-5,10-12H2,1-3H3,(H,16,18)
Std. InChIKey: HUNIPYLVUPMFCZ-UHFFFAOYSA-N
CAS NO: 1227-61-8
Molecular Formula: C15H24N2O3
Molecular Weight: 280.3627
Molecular Structure :
H bond acceptors: 5
H bond donors: 1
Freely Rotating Bonds: 9
Polar Surface Area: 42.01 Å2
Index of Refraction: 1.508
Molar Refractivity: 79.38 cm3
Molar Volume: 266.1 cm3
Surface Tension: 37.3 dyne/cm
Density: 1.053 g/cm3
Flash Point: 232.2 °C
Enthalpy of Vaporization: 72.1 kJ/mol
Boiling Point: 460.4 °C at 760 mmHg
Vapour Pressure: 1.17E-08 mmHg at 25°C

N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 110mg/kg (110mg/kg)   French Medicament Patent Document. Vol. #2702M,
mouse LD50 oral 1500ug/kg (1.5mg/kg)   Chimica Therapeutica. Vol. 1, Pg. 444, 1966.
rabbit LD50 intravenous 135mg/kg (135mg/kg)   Annales Medico-Psychologiques. Vol. 123, Pg. 141, 1965.

N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide Safety Profile

Poison by ingestion and intravenous routes. When N-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamide (CAS NO.1227-61-8) is heated to decomposition, it emits toxic fumes of NOx.

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