Product Name

  • Name

    CONGOCIDINE

  • EINECS
  • CAS No. 63770-20-7
  • Density
  • Solubility
  • Melting Point
  • Formula C18H26 N10 O3 . x Cl H
  • Boiling Point 724.2°C at 760 mmHg
  • Molecular Weight 467.00
  • Flash Point 391.8°C
  • Transport Information
  • Appearance
  • Safety Poison by subcutaneous and intravenous routes. Mutation data reported. An antibacterial agent. When heated to decomposition it emits very toxic fumes of HCl and NOx.
  • Risk Codes R22
  • Molecular Structure Molecular Structure of 63770-20-7 (CONGOCIDINE)
  • Hazard Symbols Xn
  • Synonyms 1H-Pyrrole-2-carboxamide,4-[[[(aminoiminomethyl)amino]acetyl]amino]-N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-,hydrochloride (9CI); Netropsin hydrochloride (7CI)
  • PSA 208.93000
  • LogP 3.22520

Netropsin Hydrochloride Chemical Properties

Chemistry informtion about Netropsin Hydrochloride (CAS NO.63770-20-7) is:
IUPAC Name: 4-[[4-[[1-Amino-2-(Diaminomethylideneamino)Ethylidene]Amino]-1-Methylpyrrole-2-Carbonyl]Amino]-N-(3-Amino-3-Oxopropyl)-1-Methylpyrrole-2-Carboxamide Hydrochloride
Synonyms: Congocidin Dihydrochloride ; Congocidine ; Netropsin 2HCl ; Netropsin Dihydrochloride ; Netropsin, Dihydrochloride, Streptomyces Netropsis ; Sinanomycin ; Sinanomycin Dihydrochloride
MF: C18H28Cl2N10O3
MW: 503.39 
Flash Point: 391.8 °C
Boiling Point: 724.2 °C at 760 mmHg
Vapour Pressure: 3E-21 mmHg at 25°C 
Enthalpy of Vaporization: 107.64 kJ/mol
Storage temp.: −20°C
Following is the molecular structure of Netropsin Hydrochloride (CAS NO.63770-20-7) is:

Netropsin Hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 17mg/kg (17mg/kg)   Journal of the American Chemical Society. Vol. 73, Pg. 341, 1951.
mouse LD50 oral > 300mg/kg (300mg/kg)   Journal of the American Chemical Society. Vol. 73, Pg. 341, 1951.
mouse LD50 subcutaneous 70mg/kg (70mg/kg)   Journal of the American Chemical Society. Vol. 73, Pg. 341, 1951.

Netropsin Hydrochloride Safety Profile

Poison by subcutaneous and intravenous routes. Mutation data reported. An antibacterial agent. When heated to decomposition it emits very toxic fumes of HCl and NOx
Hazard Codes:
HarmfulXn
Risk Statements:
R22:Harmful if swallowed. 
Safety Statements:
S36:Wear suitable protective clothing. 
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: DW2973000

Netropsin Hydrochloride Specification

Netropsin Hydrochloride (CAS NO.63770-20-7) is a faint yellow powder. Unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin Hydrochloride disrupts the cell cycle, prolonging G and arresting in G.

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View