-
Name
Oryzaemate
- EINECS
- CAS No. 27605-76-1
- Article Data15
- CAS DataBase
- Density 1.33 g/cm3
- Solubility 150 mg l-1
- Melting Point 136～141℃
- Formula C10H9NO3S
- Boiling Point 369 °C at 760 mmHg
- Molecular Weight 223.252
- Flash Point 177 °C
- Transport Information
- Appearance
- Safety
- Risk Codes R22; R20/21/22; R36/37/38
-
Molecular Structure
-
Hazard Symbols
Xn,
Xi
- Synonyms 1,2-Benzisothiazole,3-(2-propenyloxy)-, 1,1-dioxide (9CI);1,2-Benzisothiazole, 3-(allyloxy)-,1,1-dioxide (8CI);3-Allyloxy-1,2-benzisothiazol-1,1-dioxide;3-Allyloxy-1,2-benzisothiazole 1,1-dioxide;3-Allyloxy-1,2-benzisothiazole-1,1-oxide;Oryzemate;PO 20;PO 20(pharmaceutical);Probenazole;
- PSA 64.11000
- LogP 1.85450
Oryzaemate Chemical Properties
Chemistry informtion about Oryzaemate (27605-76-1) is:
IUPAC Name: 3-prop-2-enoxy-1,2-benzothiazole 1,1-dioxide
Synonyms: Allyloxy-1,2-Benz[D]Isothiazole-1,1-Dioxide ; Oryzamate(R) ; Oryzemate;Probenazole ; 1,2-Benzisothiazole,3-(2-Propenyloxy)-,1,1-Dioxide ; 1,2-Benzisothiazole,3-(Allyloxy)-,1,1-Dioxide ; 3-(2-Propenyloxy)-1,2-Benzisothiazole1,1-Dioxide ; 3-(Allyloxy)-1,2-Benzisothiazole1,1-Dioxide
MF: C10H9NO3S
MW: 223.25
Density: 1.33 g/cm3
Flash Point: 177 °C
Boiling Point: 369 °C at 760 mmHg
Vapour Pressure: 2.6E-05 mmHg at 25°C
Enthalpy of Vaporization: 59.15 kJ/mol
Storage temp.: 0-6°C
Following is the molecular structure of Oryzaemate (27605-76-1) is:
Oryzaemate Toxicity Data With Reference
| Organism | Test | Route | Reported Dose (Normalized Dose) | Effect | Source |
| mouse | LD50 | intraperitoneal | 745mg/kg (745mg/kg) | Behavioral: somnolence (general depressed activity) | Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 205, 1977. |
| mouse | LD50 | oral | 2750mg/kg (2750mg/kg) | Behavioral: altered sleep time (including change in righting reflex) behavioral: ataxia | Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 205, 1977. |
| mouse | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | | Japan Pesticide Information. Vol. (37), Pg. 37, 1980. |
| rat | LD50 | intraperitoneal | 850mg/kg (850mg/kg) | | Oyo Yakuri. Pharmacometrics. Vol. 13, Pg. 219, 1977. |
| rat | LD50 | oral | 2030mg/kg (2030mg/kg) | | Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 7, Pg. 307, 1982. |
| rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | | Japan Pesticide Information. Vol. (37), Pg. 37, 1980. |
Oryzaemate Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SOx and NOx.
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