Product Name

  • Name

    OXACILLIN SODIUM

  • EINECS 214-636-3
  • CAS No. 1173-88-2
  • Article Data3
  • CAS DataBase
  • Density 1.49g/cm3
  • Solubility
  • Melting Point 188 °C
  • Formula C19H18N3NaO5S
  • Boiling Point 686.8 °C at 760 mmHg
  • Molecular Weight 423.425
  • Flash Point 369.2 °C
  • Transport Information
  • Appearance Crystalline
  • Safety 22-24/25
  • Risk Codes
  • Molecular Structure Molecular Structure of 1173-88-2 (OXACILLIN SODIUM)
  • Hazard Symbols IrritantXi
  • Synonyms Penicillin P 12;Penstapho;Penstaphocid;Prostaphlin;SQ 16423;Sodium(5-methyl-3-phenyl-2-isoxazoline-4-carboxamido)penicillanate;Sodium5-methyl-3-phenyl-4-isoxazolyl penicillin;Sodium[(3-phenyl-5-methyl-4-isoxazolyl)carbonyl]penicillin;Sodium oxacillin;Stapenor;Staphcillin V;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamido)-7-oxo-,monosodium salt (8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-,monosodium salt, [2S-(2a,5a,6b)]-;5-Methyl-3-phenyl-4-isoxazolyl penicillin sodiumsalt;BRL 1400;Bactocil;Bactocil sodium;Bristopen;Cryptocillin;Micropenin;Monosodium oxacillin;NSC 527712;
  • PSA 140.87000
  • LogP 0.88940

Oxacillin sodium salt Chemical Properties

IUPAC Name:  3,3-Dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; sodium
Synonyms：  4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3,3-dimethyl-6-(5-methyl-3 ; 5-Methyl-3-phenyl-4-isoxazolylpenicillin sodium ; Bactocill ; Bristopen ; Brl1400 ; Cryptocillin ; Micropenin ; Monosodiumoxacillin
The Molecular Formula of  5-Methyl-3-phenyl-4-isoxazolyl penicillin, sodium (1173-88-2) :C19H19N3NaO5S
The Molecular Weight of  5-Methyl-3-phenyl-4-isoxazolyl penicillin, sodium (1173-88-2) :424.426030 g/mol
The Molecular Structure of  5-Methyl-3-phenyl-4-isoxazolyl penicillin, sodium (1173-88-2) :
Index of Refraction: 1.678
Molar Refractivity: 101.32 cm3
Molar Volume: 268.4 cm3
Surface Tension: 77.3 dyne/cm
Density: 1.49 g/cm3
Flash Point: 369.2 °C
Enthalpy of Vaporization: 105.76 kJ/mol
Boiling Point: 686.8 °C at 760 mmHg
Vapour Pressure: 8.32E-20 mmHg at 25°C 

Oxacillin sodium salt Uses

   5-Methyl-3-phenyl-4-isoxazolyl penicillin, sodium (1173-88-2) can be used as anti-bacterial agents.

Oxacillin sodium salt Toxicity Data With Reference

1.    

orl-wmn TDLo:4560 mg/kg/11W-I:LIV,MSK

     RMMJAK    Rocky Mountain Medical Journal. 62 (1965),34.
2.    

ivn-hmn TDLo:1200 mg/kg/7D:LIV

     AIMDAP    Archives of Internal Medicine. 138 (1978),915.
3.    

scu-rat LD50:3900 µg/kg

     NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),147.
4.    

ivn-rat LD50:2150 µg/kg

     NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),147.
5.    

scu-mus LD50:2600 µg/kg

     NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),147.
6.    

ivn-mus LD50:1399 mg/kg

     FATOAO    Farmakologiya i Toksikologiya (Moscow). 31 (1968),232.

Oxacillin sodium salt Safety Profile

Poison by subcutaneous and intravenous routes. Human systemic effects by ingestion and intravenous routes: blood effects, liver function impaired and other liver changes. When heated to decomposition it emits very toxic fumes of NOx, Na2O, and SOx.
Hazard Codes: Xi
Safety Statements: 22-24/25
S22:  Do not breathe dust
24/25:  Avoid contact with skin and eyes
WGK Germany: 2

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